Result of FASTA (omim) for
pFN21AE6337
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6337, 385 aa
1>>>pF1KE6337 385 - 385 aa - 385 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6705+/-0.000436; mu= 14.8349+/- 0.027
mean_var=67.8523+/-13.394, 0's: 0 Z-trim(110.1): 43 B-trim: 328 in 3/51
Lambda= 0.155701
statistics sampled from 18391 (18420) to 18391 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.216), width: 16
Scan time: 5.770
The best scores are: opt bits E(85289)
NP_008830 (OMIM: 604526,612572) isocitrate dehydro ( 385) 2494 569.5 4.5e-162
NP_001317692 (OMIM: 604526,612572) isocitrate dehy ( 387) 2494 569.5 4.5e-162
NP_777280 (OMIM: 604526,612572) isocitrate dehydro ( 383) 2403 549.1 6.4e-156
NP_001245313 (OMIM: 604526,612572) isocitrate dehy ( 376) 2319 530.2 3e-150
NP_004126 (OMIM: 300089) isocitrate dehydrogenase ( 393) 1169 271.9 1.8e-72
NP_777358 (OMIM: 300089) isocitrate dehydrogenase ( 380) 1115 259.8 7.9e-69
NP_005521 (OMIM: 601149) isocitrate dehydrogenase ( 366) 941 220.7 4.5e-57
XP_016877607 (OMIM: 601149) PREDICTED: isocitrate ( 316) 857 201.8 1.9e-51
XP_016877609 (OMIM: 601149) PREDICTED: isocitrate ( 257) 780 184.4 2.5e-46
XP_016877608 (OMIM: 601149) PREDICTED: isocitrate ( 257) 780 184.4 2.5e-46
XP_005254393 (OMIM: 601149) PREDICTED: isocitrate ( 257) 780 184.4 2.5e-46
>>NP_008830 (OMIM: 604526,612572) isocitrate dehydrogena (385 aa)
initn: 2494 init1: 2494 opt: 2494 Z-score: 3030.7 bits: 569.5 E(85289): 4.5e-162
Smith-Waterman score: 2494; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
:::::::::::::::::::::::::
NP_008 RDMGGYSTTTDFIKSVIGHLQTKGS
370 380
>>NP_001317692 (OMIM: 604526,612572) isocitrate dehydrog (387 aa)
initn: 2494 init1: 2494 opt: 2494 Z-score: 3030.6 bits: 569.5 E(85289): 4.5e-162
Smith-Waterman score: 2494; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
:::::::::::::::::::::::::
NP_001 RDMGGYSTTTDFIKSVIGHLQTKGSNL
370 380
>>NP_777280 (OMIM: 604526,612572) isocitrate dehydrogena (383 aa)
initn: 2427 init1: 2403 opt: 2403 Z-score: 2920.2 bits: 549.1 E(85289): 6.4e-156
Smith-Waterman score: 2403; 97.6% identity (98.7% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
:::::.: :: ..::. :
NP_777 SDMGGYATCHDFTEAVIAALPHP
370 380
>>NP_001245313 (OMIM: 604526,612572) isocitrate dehydrog (376 aa)
initn: 2319 init1: 2319 opt: 2319 Z-score: 2818.4 bits: 530.2 E(85289): 3e-150
Smith-Waterman score: 2319; 99.7% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KE6 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAALSGVRWLTRALVSAGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESAR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 AVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKIPS
310 320 330 340 350 360
370 380
pF1KE6 RDMGGYSTTTDFIKSVIGHLQTKGS
NP_001 AVPSFLLHPLPFSWAI
370
>>NP_004126 (OMIM: 300089) isocitrate dehydrogenase [NAD (393 aa)
initn: 1190 init1: 1010 opt: 1169 Z-score: 1422.0 bits: 271.9 E(85289): 1.8e-72
Smith-Waterman score: 1169; 54.6% identity (78.5% similar) in 335 aa overlap (47-381:53-384)
20 30 40 50 60 70
pF1KE6 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
: :::.::::.::::: :: ::. : :
NP_004 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE6 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
NP_004 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
90 100 110 120 130
140 150 160 170 180 190
pF1KE6 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
NP_004 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE6 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
NP_004 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE6 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
NP_004 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE6 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
.::::::: ::.. :: ::.:. ... : :: . ...: :.:: .::.. :..:
NP_004 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV
320 330 340 350 360 370
380
pF1KE6 IGHLQTKGS
: :..
NP_004 IRHIRVINGRAVEA
380 390
>>NP_777358 (OMIM: 300089) isocitrate dehydrogenase [NAD (380 aa)
initn: 993 init1: 965 opt: 1115 Z-score: 1356.7 bits: 259.8 E(85289): 7.9e-69
Smith-Waterman score: 1115; 55.9% identity (78.3% similar) in 313 aa overlap (47-359:53-362)
20 30 40 50 60 70
pF1KE6 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
: :::.::::.::::: :: ::. : :
NP_777 CRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACV
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE6 PVEFQEHHLSEVQNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKL
::.:.: :.: . :.:: ..... ....:.::. :.:.: . : . :: .:
NP_777 PVDFEEVHVS---SNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSL
90 100 110 120 130
140 150 160 170 180 190
pF1KE6 DLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQR
::.:::.: ::::: .:::...:..:.::.::::::::::::. ::.: :::.:.::: :
NP_777 DLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLR
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE6 IAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQ
::..:: : ..:: ::::::::::::::::::::::.::: ::.: ::.::.:: ::
NP_777 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ
200 210 220 230 240 250
260 270 280 290 300 310
pF1KE6 LVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG
::. : ::::.:::::::::..:. :::::: :.: : .:. ::::::..:. . ..
NP_777 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIAN
260 270 280 290 300 310
320 330 340 350 360 370
pF1KE6 RNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSV
.::::::: ::.. :: ::.:. ... : :: . .::
NP_777 KNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENVRFPSHPTLLPRPVSPCSL
320 330 340 350 360 370
380
pF1KE6 IGHLQTKGS
NP_777 L
380
>>NP_005521 (OMIM: 601149) isocitrate dehydrogenase [NAD (366 aa)
initn: 935 init1: 768 opt: 941 Z-score: 1145.7 bits: 220.7 E(85289): 4.5e-57
Smith-Waterman score: 941; 45.0% identity (75.4% similar) in 333 aa overlap (47-376:30-358)
20 30 40 50 60 70
pF1KE6 AGNPGAWRGLSTSAAAHAASRSQAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAV
: ::..::::.:::. :: ..: :: .
NP_005 MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKA
10 20 30 40 50
80 90 100 110 120 130
pF1KE6 PVEFQEHHLSEVQNMASEEKLE-QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRK
:....:.... .:. ... . .. :: .::... : ..::. :. :... ::.
NP_005 PIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKT
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE6 LDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQ
.::.::: :. :: : ......: :::.::::::..:: . ::.. .:..:.. :.
NP_005 FDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASK
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE6 RIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCM
:::.:::.:: .. :..::::::::::...:::::: :.:::: :::. : .:. :.
NP_005 RIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCL
180 190 200 210 220 230
260 270 280 290 300 310
pF1KE6 QLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQA
..::.: ::::::::::::.:...: :::.:: ::.:. . .:. :.::. : :
NP_005 NMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPD
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE6 V-GRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFI
. :...:::::.:::: ::::..: :.. : : .:: :: :.:.:: . .::
NP_005 IAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFT
300 310 320 330 340 350
380
pF1KE6 KSVIGHLQTKGS
. .
NP_005 EEICRRVKDLD
360
>>XP_016877607 (OMIM: 601149) PREDICTED: isocitrate dehy (316 aa)
initn: 805 init1: 768 opt: 857 Z-score: 1044.7 bits: 201.8 E(85289): 1.9e-51
Smith-Waterman score: 857; 44.4% identity (75.6% similar) in 311 aa overlap (69-376:2-308)
40 50 60 70 80 90
pF1KE6 QAEDVRVEGSFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKLE
..: :: .:....:.... .:. ... .
XP_016 MKIFDAAKAPIQWEERNVTAIQGPGGKWMIP
10 20 30
100 110 120 130 140 150
pF1KE6 -QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNN
.. :: .::... : ..::. :. :... ::. .::.::: :. :: : ...
XP_016 SEAKESMDKNKMGLKGPLKTPIA-AGH-PSMNLLLRKTFDLYANVRPCVSIEGYKTPYTD
40 50 60 70 80
160 170 180 190 200 210
pF1KE6 LDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVH
...: :::.::::::..:: . ::.. .:..:.. :.:::.:::.:: .. :..:::::
XP_016 VNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVH
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE6 KANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNII
:::::...:::::: :.:::: :::. : .:. :...::.: ::::::::::::.:.
XP_016 KANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDIL
150 160 170 180 190 200
280 290 300 310 320 330
pF1KE6 DNLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQAV-GRNIANPTAMLLSASNMLRH
..: :::.:: ::.:. . .:. :.::. : : . :...:::::.:::: ::::
XP_016 SDLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPDIAGKDMANPTALLLSAVMMLRH
210 220 230 240 250 260
340 350 360 370 380
pF1KE6 LNLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS
..: :.. : : .:: :: :.:.:: . .:: . .
XP_016 MGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
270 280 290 300 310
>>XP_016877609 (OMIM: 601149) PREDICTED: isocitrate dehy (257 aa)
initn: 787 init1: 768 opt: 780 Z-score: 952.7 bits: 184.4 E(85289): 2.5e-46
Smith-Waterman score: 780; 49.2% identity (76.8% similar) in 250 aa overlap (129-376:2-249)
100 110 120 130 140 150
pF1KE6 QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNL
.. ::. .::.::: :. :: : ....
XP_016 MNLLLRKTFDLYANVRPCVSIEGYKTPYTDV
10 20 30
160 170 180 190 200 210
pF1KE6 DLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHK
..: :::.::::::..:: . ::.. .:..:.. :.:::.:::.:: .. :..::::::
XP_016 NIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHK
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE6 ANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIID
::::...:::::: :.:::: :::. : .:. :...::.: ::::::::::::.:..
XP_016 ANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE6 NLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQAV-GRNIANPTAMLLSASNMLRHL
.: :::.:: ::.:. . .:. :.::. : : . :...:::::.:::: ::::.
XP_016 DLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPDIAGKDMANPTALLLSAVMMLRHM
160 170 180 190 200
340 350 360 370 380
pF1KE6 NLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS
.: :.. : : .:: :: :.:.:: . .:: . .
XP_016 GLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
210 220 230 240 250
>>XP_016877608 (OMIM: 601149) PREDICTED: isocitrate dehy (257 aa)
initn: 787 init1: 768 opt: 780 Z-score: 952.7 bits: 184.4 E(85289): 2.5e-46
Smith-Waterman score: 780; 49.2% identity (76.8% similar) in 250 aa overlap (129-376:2-249)
100 110 120 130 140 150
pF1KE6 QVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNL
.. ::. .::.::: :. :: : ....
XP_016 MNLLLRKTFDLYANVRPCVSIEGYKTPYTDV
10 20 30
160 170 180 190 200 210
pF1KE6 DLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHK
..: :::.::::::..:: . ::.. .:..:.. :.:::.:::.:: .. :..::::::
XP_016 NIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHK
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE6 ANIMKLGDGLFLQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIID
::::...:::::: :.:::: :::. : .:. :...::.: ::::::::::::.:..
XP_016 ANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILS
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE6 NLAAGLVGGAGVVPGESYSAE-YAVFETGARHPFAQAV-GRNIANPTAMLLSASNMLRHL
.: :::.:: ::.:. . .:. :.::. : : . :...:::::.:::: ::::.
XP_016 DLCAGLIGGLGVTPSGNIGANGVAIFES--VHGTAPDIAGKDMANPTALLLSAVMMLRHM
160 170 180 190 200
340 350 360 370 380
pF1KE6 NLEYHSSMIADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTKGS
.: :.. : : .:: :: :.:.:: . .:: . .
XP_016 GLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD
210 220 230 240 250
385 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:14:20 2016 done: Tue Nov 8 12:14:21 2016
Total Scan time: 5.770 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]