Result of FASTA (ccds) for
pFN21AE6323
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6323, 440 aa
1>>>pF1KE6323 440 - 440 aa - 440 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3448+/-0.00105; mu= 12.2815+/- 0.063
mean_var=92.3861+/-18.582, 0's: 0 Z-trim(105.3): 48 B-trim: 0 in 0/51
Lambda= 0.133435
statistics sampled from 8321 (8364) to 8321 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.257), width: 16
Scan time: 1.820
The best scores are: opt bits E(32554)
CCDS5424.1 PLEKHA8 gene_id:84725|Hs108|chr7 ( 440) 2888 566.5 1.8e-161
CCDS75574.1 PLEKHA8 gene_id:84725|Hs108|chr7 ( 459) 2847 558.6 4.5e-159
CCDS56473.1 PLEKHA8 gene_id:84725|Hs108|chr7 ( 519) 2847 558.7 5e-159
CCDS33336.1 PLEKHA3 gene_id:65977|Hs108|chr2 ( 300) 843 172.8 4.3e-43
CCDS55598.1 OSBPL9 gene_id:114883|Hs108|chr1 ( 723) 290 66.5 1e-10
>>CCDS5424.1 PLEKHA8 gene_id:84725|Hs108|chr7 (440 aa)
initn: 2888 init1: 2888 opt: 2888 Z-score: 3012.3 bits: 566.5 E(32554): 1.8e-161
Smith-Waterman score: 2888; 100.0% identity (100.0% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::::::::::
CCDS54 EVKNGEKDIQTALRNPTENT
430 440
>>CCDS75574.1 PLEKHA8 gene_id:84725|Hs108|chr7 (459 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2969.4 bits: 558.6 E(32554): 4.5e-159
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
CCDS75 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFAGHTNV
430 440 450
>>CCDS56473.1 PLEKHA8 gene_id:84725|Hs108|chr7 (519 aa)
initn: 2900 init1: 2847 opt: 2847 Z-score: 2968.5 bits: 558.7 E(32554): 5e-159
Smith-Waterman score: 2847; 99.8% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEINGEEEILMKNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 NSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSGSDSSCSPECL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 WEEGKEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLT
370 380 390 400 410 420
430 440
pF1KE6 EVKNGEKDIQTALRNPTENT
::::::::::::: :
CCDS56 EVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTVKEGDHQKE
430 440 450 460 470 480
>>CCDS33336.1 PLEKHA3 gene_id:65977|Hs108|chr2 (300 aa)
initn: 889 init1: 729 opt: 843 Z-score: 887.2 bits: 172.8 E(32554): 4.3e-43
Smith-Waterman score: 853; 62.0% identity (84.0% similar) in 213 aa overlap (1-203:1-213)
10 20 30 40 50 60
pF1KE6 MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTR
::::::::::::.:::::::.: .:::::::: .:. :: ::::.::::::.:::.::::
CCDS33 MEGVLYKWTNYLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSEL
:.:::::::.::.:: ..::::::::::::.::::::.::.::::..:..:.::::::::
CCDS33 MELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLTDTRTKKEKEISETSESLKTKMSEL
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 RLYCDLLVQQVDKTKEVT---TTGVSNSEEGID-VGTLLKSTCNTFLKTLEECMQIANAA
:::::::.::: .: . . : : :... ...::..:::::. :::::..::::
CCDS33 RLYCDLLMQQVHTIQEFVHHDENHSSPSAENMNEASSLLSATCNTFITTLEECVKIANAK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 FTSELL---YRTP---PGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEIN
: :.. . : : ::. ... . ...::
CCDS33 FKPEMFQLHHPDPLVSPVSPSPVQMMKRSVSHPGSCSSERSSHSIKEPVSTLHRLSQRRR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 GEEEILMKNKNSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQSG
CCDS33 RTYSDTDSCSDIPLEDPDRPVHCSKNTLNGDLASATIPEESRLMAKKQSESEDTLPSFSS
250 260 270 280 290 300
>>CCDS55598.1 OSBPL9 gene_id:114883|Hs108|chr1 (723 aa)
initn: 217 init1: 119 opt: 290 Z-score: 306.1 bits: 66.5 E(32554): 1e-10
Smith-Waterman score: 290; 26.7% identity (61.9% similar) in 210 aa overlap (1-203:5-211)
10 20 30 40 50
pF1KE6 MEGVLYKWTNYLSGWQPRWFLL--CGGILSYYDSPEDAWKGCK-GSIQMAVCEIQV
::: : :::: ..::: :::.: .:.:::: : . .: . : ... : .
CCDS55 MASIMEGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 HSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENL
. :.. . . . .. :...::.. ::..:. :: . : . .. :. .....
CCDS55 DDEDDSTFTITVD-QKTFHFQARDADEREKWIHALEETILRHTLQLQGLDSGFVPSVQDF
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 KTKMSELRLYCDLLVQQVDKTKEVTTTGVSNSEEGIDVGTLLKSTCNTFLKTLEEC---M
:..: : ..:..:. : . . ...:. . :: : : :........: .
CCDS55 DKKLTEADAYLQILIEQL-KLFDDKLQNCKEDEQRKKIETL-KETTNSMVESIKHCIVLL
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 QIANAAFTS-ELLYRTPPGSPQLAMLKSSKMKHPIIPIHNSLERQMELSTCENGSLNMEI
:::..... . .:. : : .. . :. . :
CCDS55 QIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 NGEEEILMKNKNSLYLKSAEIDCSISSEENTDDNITVQGEIRKEDGMENLKNHDNNLTQS
CCDS55 HQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKR
240 250 260 270 280 290
440 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:06:02 2016 done: Tue Nov 8 12:06:02 2016
Total Scan time: 1.820 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]