Result of FASTA (omim) for
pFN21AE6316
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6316, 418 aa
1>>>pF1KE6316 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7605+/-0.00037; mu= 20.2039+/- 0.023
mean_var=61.7424+/-12.753, 0's: 0 Z-trim(112.9): 29 B-trim: 65 in 1/52
Lambda= 0.163223
statistics sampled from 22034 (22057) to 22034 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.259), width: 16
Scan time: 6.760
The best scores are: opt bits E(85289)
NP_001121082 (OMIM: 602938,607748) bile acid-CoA:a ( 418) 2789 665.4 7.2e-191
NP_001692 (OMIM: 602938,607748) bile acid-CoA:amin ( 418) 2789 665.4 7.2e-191
NP_001032238 (OMIM: 614313) acyl-coenzyme A thioes ( 421) 1151 279.7 9.4e-75
NP_006812 (OMIM: 609972) acyl-coenzyme A thioester ( 483) 1150 279.5 1.2e-74
NP_689544 (OMIM: 614314) acyl-coenzyme A thioester ( 421) 1112 270.5 5.5e-72
XP_011535378 (OMIM: 614267) PREDICTED: putative ac ( 459) 1008 246.1 1.4e-64
XP_016877078 (OMIM: 614313) PREDICTED: acyl-coenzy ( 304) 739 182.6 1.2e-45
XP_016877079 (OMIM: 614313) PREDICTED: acyl-coenzy ( 298) 738 182.4 1.4e-45
XP_006720070 (OMIM: 609972) PREDICTED: acyl-coenzy ( 286) 736 181.9 1.8e-45
XP_016876426 (OMIM: 609972) PREDICTED: acyl-coenzy ( 309) 723 178.8 1.6e-44
XP_016877080 (OMIM: 614313) PREDICTED: acyl-coenzy ( 259) 692 171.5 2.2e-42
XP_016877081 (OMIM: 614313) PREDICTED: acyl-coenzy ( 259) 692 171.5 2.2e-42
NP_001032239 (OMIM: 614267) putative acyl-coenzyme ( 207) 382 98.4 1.8e-20
>>NP_001121082 (OMIM: 602938,607748) bile acid-CoA:amino (418 aa)
initn: 2789 init1: 2789 opt: 2789 Z-score: 3547.7 bits: 665.4 E(85289): 7.2e-191
Smith-Waterman score: 2789; 99.8% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KE6 MIQLTATPVSALVDEPVHIQATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDL
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_001 MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 APKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 GLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGA
310 320 330 340 350 360
370 380 390 400 410
pF1KE6 GHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
370 380 390 400 410
>>NP_001692 (OMIM: 602938,607748) bile acid-CoA:amino ac (418 aa)
initn: 2789 init1: 2789 opt: 2789 Z-score: 3547.7 bits: 665.4 E(85289): 7.2e-191
Smith-Waterman score: 2789; 99.8% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KE6 MIQLTATPVSALVDEPVHIQATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDL
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
NP_001 MIQLTATPVSALVDEPVHIRATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEVDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 APKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 GLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTQVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGA
310 320 330 340 350 360
370 380 390 400 410
pF1KE6 GHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHLIEPPYSPLCCASTTHDLRLHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
370 380 390 400 410
>>NP_001032238 (OMIM: 614313) acyl-coenzyme A thioestera (421 aa)
initn: 1172 init1: 543 opt: 1151 Z-score: 1463.0 bits: 279.7 E(85289): 9.4e-75
Smith-Waterman score: 1151; 45.9% identity (72.3% similar) in 401 aa overlap (14-410:16-410)
10 20 30 40 50
pF1KE6 MIQLTATPVSALVDEPVHIQATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEV
::::.: . :: : : :...:::.::.: .: ..:.:::. .::.
NP_001 MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGEL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 DLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKV
::..: .:::.. :..::::.:.:.::: :.::.:::: :. :.... : . ...
NP_001 DLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDV-RTPLAVELEVLDGHDPDPGRL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 ASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRA
. ::... ::: : :: ::.::.::::: : :::..:.:: :::::.::
NP_001 LCRVRH----ERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGV
::::..::: .::::.::::::. :. :::::::.:.:: ::.: : :::.... .:
NP_001 SLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRT
.. :::: .:: .::.:.:::. : :.:. :. . . :... : .. .
NP_001 ELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 FETTQVGASQYLF-PIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSY
... : .: : :.:.:.. :::.::. :.. .:. .:..: .:. ::. . .. :
NP_001 LNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICY
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 PGAGHLIEPPYSPLCCASTTHDLR---LHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDV
: .:: ::::: ::: :: : : . :::: :: :: :::..: :..:::
NP_001 PETGHYIEPPYFPLCRASL-HALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHE
360 370 380 390 400 410
pF1KE6 TSQL
NP_001 GTIPSKV
420
>>NP_006812 (OMIM: 609972) acyl-coenzyme A thioesterase (483 aa)
initn: 1169 init1: 540 opt: 1150 Z-score: 1460.9 bits: 279.5 E(85289): 1.2e-74
Smith-Waterman score: 1150; 45.9% identity (72.1% similar) in 401 aa overlap (14-410:78-472)
10 20 30 40
pF1KE6 MIQLTATPVSALVDEPVHIQATGLIPFQMVSFQASLEDENGDM
::::.: . :: : : :...:::.::.: .
NP_006 PQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGAL
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE6 FYSQAHYRANEFGEVDLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQV
: ..:.:::. .::.::..: .:::.. :..::::.:.:.::: :.::.:::: :. :
NP_006 FQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDV-RTPLAV
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE6 QVKLYDLELIVNNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGV
.... : . ... . ::... ::: : :: ::.::.::::: : :::.
NP_006 ELEVLDGHDPDPGRLLCQTRH----ERYFLPPGVRREPVRVGRVRGTLFLPPEPGPFPGI
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE6 IDLFGGLGGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPK
.:.:: :::::.::::::..::: .::::.::::::. :. ::::::: :.:: ::.
NP_006 VDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPE
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE6 VFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQ
: : :::.... .: .. :::: .:: .::.:.:::. : :.:. :. . .
NP_006 VKGPGVGLLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLHYKGETLPPVGVNRN
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE6 LISTNALGLLELYRTFETTQVGASQYLF-PIEEAQGQFLFIVGEGDKTINSKAHAEQAIG
:... : .. .... : .: : :.:.:.. :::.::. :.. .:. .:..:
NP_006 RIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACK
350 360 370 380 390 400
350 360 370 380 390
pF1KE6 QLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDLR---LHWGGEVIPHAAAQEHAW
.:. ::. . .. :: .:: ::::: ::: :: : : . :::: :: :: ::
NP_006 RLQAHGRRKPQIICYPETGHYIEPPYFPLCRASL-HALVGSPIIWGGEPRAHAMAQVDAW
410 420 430 440 450 460
400 410
pF1KE6 KEIQRFLRKHLIPDVTSQL
:..: :..:::
NP_006 KQLQTFFHKHLGGHEGTIPSKV
470 480
>>NP_689544 (OMIM: 614314) acyl-coenzyme A thioesterase (421 aa)
initn: 1144 init1: 536 opt: 1112 Z-score: 1413.4 bits: 270.5 E(85289): 5.5e-72
Smith-Waterman score: 1112; 45.6% identity (73.3% similar) in 401 aa overlap (14-410:16-410)
10 20 30 40 50
pF1KE6 MIQLTATPVSALVDEPVHIQATGLIPFQMVSFQASLEDENGDMFYSQAHYRANEFGEV
.:::.: . :: : : :...:::.::.: .: ..:.: :. ::.
NP_689 MSATLILEPPGRCCWNEPVRIAVRGLAPEQRVTLRASLRDEKGALFRAHARYCADARGEL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 DLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQVQVKLYDLELIVNNKV
::..: .:::.. :..::::.:.:.::: . :.:::::. :: :.... : . ...
NP_689 DLERAPALGGSFAGLEPMGLLWALEPEKPFWRFLKRDVQI-PFVVELEVLDGHDPEPGRL
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 ASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRA
. :: .. ::: : .:: ::.:..:::::: : :::.::.:: :::::.::
NP_689 LCQAQH----ERHFLPPGVRRQSVRAGRVRATLFLPPGPGPFPGIIDIFGIGGGLLEYRA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGV
::::..:::.:::::.:.:::: . . .:::::::. ..:.::.: : :.:.... :.
NP_689 SLLAGHGFATLALAYYNFEDLPNNMDNISLEYFEEAVCYMLQHPQVKGPGIGLLGISLGA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRT
.: :::: .::.:.::: :::... . :. . :: .. . :.. ::...
NP_689 DICLSMASFLKNVSATVSINGSGISGNTAINYKHSSIPPLGYDLRRIKVAFSGLVDIV-D
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 FETTQVGASQY--LFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLS
.... ::. . ..:::.::: .:.:::. :.. :. .:. . .:. :::.. ..
NP_689 IRNALVGGYKNPSMIPIEKAQGPILLIVGQDDHNWRSELYAQTVSERLQAHGKEKPQIIC
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 YPGAGHLIEPPYSPLCCASTTHDLRLH--WGGEVIPHAAAQEHAWKEIQRFLRKHLIPDV
:::.:: ::::: ::: :: . : : :::: :. ::: :::.: :. :::
NP_689 YPGTGHYIEPPYFPLCPASLHRLLNKHVIWGGEPRAHSKAQEDAWKQILAFFCKHLGGTQ
360 370 380 390 400 410
pF1KE6 TSQL
NP_689 KTAVPKL
420
>>XP_011535378 (OMIM: 614267) PREDICTED: putative acyl-c (459 aa)
initn: 1009 init1: 461 opt: 1008 Z-score: 1280.5 bits: 246.1 E(85289): 1.4e-64
Smith-Waterman score: 1008; 43.5% identity (68.8% similar) in 400 aa overlap (14-410:54-448)
10 20 30 40
pF1KE6 MIQLTATPVSALVDEPVHIQATGLIPFQMVSFQASLEDENGDM
:::..: . :: : : :....::.::.: .
XP_011 TDSAELGRPCSTQIGMAATLILEPAGRCCWDEPLRIAVRGLAPEQPVTLRTSLRDEEGAL
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE6 FYSQAHYRANEFGEVDLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQV
: ..:.:::. :.::..: .:::.. :..::::.:.:.::: :.::.:::: :: :
XP_011 FRAHARYRADARDELDLERAPALGGSFAGLQPMGLLWALEPEKALVRLVKRDV-RTPFAV
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE6 QVKLYDLELIVNNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGV
.... : . ... . .: .. ::: : :: : .:.:::::: :: :::.
XP_011 ELEVLDGHDTEPGRLLCLAQN----KRDFLRPGVRREPVRAGPVRAALFLPPDEGPFPGI
150 160 170 180 190
170 180 190 200 210 220
pF1KE6 IDLFGGLGGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPK
:::::. :: :.::::::..::: ::::: .::::. . . :::::::..:.:.:::
XP_011 IDLFGSSRGLCEYRASLLAGHGFAVLALAYFRFEDLPEDLNDVHLEYFEEAVDFMLQHPK
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE6 VFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQ
: : ...... .: .. :::: .:: .:::::::. : :. .: : .
XP_011 VKGPSIALLGFSKGGDLCLSMASFLKGITATVLINACVANTVAPLHYKDMIIPKLVDDLG
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE6 LISTNALGLLELYRTFETT-QVGASQYLFPIEEAQGQFLFIVGEGDKTINSKAHAEQAIG
.. . :.: .. :. . . : : :.:.:: :::::: :.. .:. .:. :
XP_011 KVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASE
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE6 QLKRHGKNNWTLLSYPGAGHLIEPPYSPLCCASTTHDL--RLHWGGEVIPHAAAQEHAWK
.:. :::. .. :: .:: :.::: : ::. : . .::: :. :: ::.
XP_011 RLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDAWQ
380 390 400 410 420 430
410
pF1KE6 EIQRFLRKHLIPDVTSQL
.:: :..:::
XP_011 QIQTFFHKHLNGKKSVKHSKI
440 450
>>XP_016877078 (OMIM: 614313) PREDICTED: acyl-coenzyme A (304 aa)
initn: 717 init1: 420 opt: 739 Z-score: 940.7 bits: 182.6 E(85289): 1.2e-45
Smith-Waterman score: 739; 44.9% identity (69.3% similar) in 274 aa overlap (145-410:23-293)
120 130 140 150 160 170
pF1KE6 NNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFL----PPGEGLFPGVIDLFGGL
:: :. .: :: :::..:.::
XP_016 MNKVTINTCQKFLDEHRFSFLVGRYLGVGLLGHMCEPGP--FPGIVDMFGTG
10 20 30 40 50
180 190 200 210 220 230
pF1KE6 GGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVG
:::::.::::::..::: .::::.::::::. :. :::::::.:.:: ::.: : :::
XP_016 GGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVG
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE6 VVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNAL
.... .: .. :::: .:: .::.:.:::. : :.:. :. . . :...
XP_016 LLGISKGGELCLSMASFLKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKD
120 130 140 150 160 170
300 310 320 330 340
pF1KE6 GLLELYRTFETTQVGASQYLF-PIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGK
: .. .... : .: : :.:.:.. :::.::. :.. .:. .:..: .:. ::.
XP_016 GYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGR
180 190 200 210 220 230
350 360 370 380 390 400
pF1KE6 NNWTLLSYPGAGHLIEPPYSPLCCASTTHDLR---LHWGGEVIPHAAAQEHAWKEIQRFL
. .. :: .:: ::::: ::: :: : : . :::: :: :: :::..: :.
XP_016 RKPQIICYPETGHYIEPPYFPLCRASL-HALVGSPIIWGGEPRAHAMAQVDAWKQLQTFF
240 250 260 270 280
410
pF1KE6 RKHLIPDVTSQL
.:::
XP_016 HKHLGGHEGTIPSKV
290 300
>>XP_016877079 (OMIM: 614313) PREDICTED: acyl-coenzyme A (298 aa)
initn: 717 init1: 420 opt: 738 Z-score: 939.5 bits: 182.4 E(85289): 1.4e-45
Smith-Waterman score: 738; 45.9% identity (71.2% similar) in 257 aa overlap (158-410:32-287)
130 140 150 160 170 180
pF1KE6 LERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASLLASRGFA
: :::..:.:: :::::.::::::..:::
XP_016 LRSGTQILVKNDELVKVQLFQELQVTGREPGPFPGIVDMFGTGGGLLEYRASLLAGKGFA
10 20 30 40 50 60
190 200 210 220 230 240
pF1KE6 SLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQIGLSMAIY
.::::.::::::. :. :::::::.:.:: ::.: : :::.... .: .. :::: .
XP_016 VMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASF
70 80 90 100 110 120
250 260 270 280 290 300
pF1KE6 LKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFETTQVGAS
:: .::.:.:::. : :.:. :. . . :... : .. .... : .
XP_016 LKGITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPD
130 140 150 160 170 180
310 320 330 340 350 360
pF1KE6 QYLF-PIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGAGHLIEP
: : :.:.:.. :::.::. :.. .:. .:..: .:. ::. . .. :: .:: :::
XP_016 QKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEP
190 200 210 220 230 240
370 380 390 400 410
pF1KE6 PYSPLCCASTTHDLR---LHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
:: ::: :: : : . :::: :: :: :::..: :..:::
XP_016 PYFPLCRASL-HALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
250 260 270 280 290
>>XP_006720070 (OMIM: 609972) PREDICTED: acyl-coenzyme A (286 aa)
initn: 716 init1: 419 opt: 736 Z-score: 937.2 bits: 181.9 E(85289): 1.8e-45
Smith-Waterman score: 736; 45.9% identity (70.8% similar) in 257 aa overlap (158-410:20-275)
130 140 150 160 170 180
pF1KE6 LERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGVIDLFGGLGGLLEFRASLLASRGFA
: :::..:.:: :::::.::::::..:::
XP_006 MEPEEFGAVPGVSTAEAEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFA
10 20 30 40
190 200 210 220 230 240
pF1KE6 SLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPKVFGSGVGVVSVCQGVQIGLSMAIY
.::::.::::::. :. ::::::: :.:: ::.: : :::.... .: .. :::: .
XP_006 VMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELCLSMASF
50 60 70 80 90 100
250 260 270 280 290 300
pF1KE6 LKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQLISTNALGLLELYRTFETTQVGAS
:: .::.:.:::. : :.:. :. . . :... : .. .... : .
XP_006 LKGITAAVVINGSVANVGGTLHYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPD
110 120 130 140 150 160
310 320 330 340 350 360
pF1KE6 QYLF-PIEEAQGQFLFIVGEGDKTINSKAHAEQAIGQLKRHGKNNWTLLSYPGAGHLIEP
: : :.:.:.. :::.::. :.. .:. .:..: .:. ::. . .. :: .:: :::
XP_006 QKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEP
170 180 190 200 210 220
370 380 390 400 410
pF1KE6 PYSPLCCASTTHDLR---LHWGGEVIPHAAAQEHAWKEIQRFLRKHLIPDVTSQL
:: ::: :: : : . :::: :: :: :::..: :..:::
XP_006 PYFPLCRASL-HALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV
230 240 250 260 270 280
>>XP_016876426 (OMIM: 609972) PREDICTED: acyl-coenzyme A (309 aa)
initn: 758 init1: 426 opt: 723 Z-score: 920.2 bits: 178.8 E(85289): 1.6e-44
Smith-Waterman score: 723; 52.1% identity (77.7% similar) in 211 aa overlap (14-224:78-283)
10 20 30 40
pF1KE6 MIQLTATPVSALVDEPVHIQATGLIPFQMVSFQASLEDENGDM
::::.: . :: : : :...:::.::.: .
XP_016 PQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGAL
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE6 FYSQAHYRANEFGEVDLNHASSLGGDYMGVHPMGLFWSLKPEKLLTRLLKRDVMNRPFQV
: ..:.:::. .::.::..: .:::.. :..::::.:.:.::: :.::.:::: :. :
XP_016 FQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDV-RTPLAV
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE6 QVKLYDLELIVNNKVASAPKASLTLERWYVAPGVTRIKVREGRLRGALFLPPGEGLFPGV
.... : . ... . ::... ::: : :: ::.::.::::: : :::.
XP_016 ELEVLDGHDPDPGRLLCQTRH----ERYFLPPGVRREPVRVGRVRGTLFLPPEPGPFPGI
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE6 IDLFGGLGGLLEFRASLLASRGFASLALAYHNYEDLPRKPEVTDLEYFEEAANFLLRHPK
.:.:: :::::.::::::..::: .::::.::::::. :. ::::::: :.:: ::.
XP_016 VDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPE
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE6 VFGSGVGVVSVCQGVQIGLSMAIYLKQVTATVLINGTNFPFGIPQVYHGQIHQPLPHSAQ
.
XP_016 MESCCVTQAGVQWHDLGSLQTPPPRFN
290 300
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:01:59 2016 done: Tue Nov 8 12:02:00 2016
Total Scan time: 6.760 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]