Result of FASTA (ccds) for
pFN21AE6285
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6285, 279 aa
1>>>pF1KE6285 279 - 279 aa - 279 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6705+/-0.00087; mu= 13.2323+/- 0.052
mean_var=66.5851+/-13.277, 0's: 0 Z-trim(106.0): 15 B-trim: 0 in 0/51
Lambda= 0.157176
statistics sampled from 8721 (8730) to 8721 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.268), width: 16
Scan time: 1.880
The best scores are: opt bits E(32554)
CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 ( 279) 1896 438.7 2.2e-123
CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX ( 357) 673 161.4 8.5e-40
CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX ( 353) 641 154.1 1.3e-37
CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 ( 290) 597 144.1 1.1e-34
CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 ( 291) 457 112.4 3.9e-25
CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 ( 303) 317 80.6 1.5e-15
>>CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 (279 aa)
initn: 1896 init1: 1896 opt: 1896 Z-score: 2328.5 bits: 438.7 E(32554): 2.2e-123
Smith-Waterman score: 1896; 100.0% identity (100.0% similar) in 279 aa overlap (1-279:1-279)
10 20 30 40 50 60
pF1KE6 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 MLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 LKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPN
190 200 210 220 230 240
250 260 270
pF1KE6 NTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
:::::::::::::::::::::::::::::::::::::::
CCDS31 NTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
250 260 270
>>CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX (357 aa)
initn: 518 init1: 220 opt: 673 Z-score: 828.0 bits: 161.4 E(32554): 8.5e-40
Smith-Waterman score: 673; 38.3% identity (72.6% similar) in 274 aa overlap (11-275:84-353)
10 20 30 40
pF1KE6 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLIL
:.: . ....: ::.::..::.:::
CCDS48 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLIL
60 70 80 90 100 110
50 60 70 80 90 100
pF1KE6 LFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDP
:.:. ::. :::.... :.... :.. .: . ... ::.:. : . .:...:. :.:
CCDS48 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPF-AHSLNFNFNVSEP
120 130 140 150 160 170
110 120 130 140 150
pF1KE6 TSYAGYIEDLKKFLKPYTLEEQKNLTV-CPDGALFEQKGPV---YVACQFPISLLQACSG
.. :. .:. ::. :. :....: :: : : : : :::: :.:. :::
CCDS48 DTWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSG
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE6 MNDPDFGYSQGNPCILVKMNRIIGLKPE-GVP-RIDC-VSKNE--DIPNVAVYPHNGMID
..:: :::: :.::::.:::::.:..:: : : ...: :.... :: ... ::... .:
CCDS48 LEDPTFGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFD
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE6 LKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRV
:.:.::::: ::.: .::::.. . . .: . : :.:.. :.. ... . :.:.:::
CCDS48 LRYYPYYGKLTHVNYTSPLVAMHFTDVVKN--QAVPVQCQLKGKGVINDVIN-DRFVGRV
300 310 320 330 340
pF1KE6 MFKITARA
.: .
CCDS48 IFTLNIET
350
>>CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX (353 aa)
initn: 479 init1: 220 opt: 641 Z-score: 788.8 bits: 154.1 E(32554): 1.3e-37
Smith-Waterman score: 641; 38.0% identity (71.2% similar) in 274 aa overlap (11-275:84-349)
10 20 30 40
pF1KE6 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLIL
:.: . ....: ::.:: ::::
CCDS14 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLART----GLIL
60 70 80 90 100
50 60 70 80 90 100
pF1KE6 LFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDP
:.:. ::. :::.... :.... :.. .: . ... ::.:. : . .:...:. :.:
CCDS14 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPF-AHSLNFNFNVSEP
110 120 130 140 150 160
110 120 130 140 150
pF1KE6 TSYAGYIEDLKKFLKPYTLEEQKNLTV-CPDGALFEQKGPV---YVACQFPISLLQACSG
.. :. .:. ::. :. :....: :: : : : : :::: :.:. :::
CCDS14 DTWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSG
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE6 MNDPDFGYSQGNPCILVKMNRIIGLKPE-GVP-RIDC-VSKNE--DIPNVAVYPHNGMID
..:: :::: :.::::.:::::.:..:: : : ...: :.... :: ... ::... .:
CCDS14 LEDPTFGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFD
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE6 LKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRV
:.:.::::: ::.: .::::.. . . .: . : :.:.. :.. ... . :.:.:::
CCDS14 LRYYPYYGKLTHVNYTSPLVAMHFTDVVKN--QAVPVQCQLKGKGVINDVIN-DRFVGRV
290 300 310 320 330 340
pF1KE6 MFKITARA
.: .
CCDS14 IFTLNIET
350
>>CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 (290 aa)
initn: 817 init1: 385 opt: 597 Z-score: 736.3 bits: 144.1 E(32554): 1.1e-34
Smith-Waterman score: 863; 47.6% identity (73.6% similar) in 288 aa overlap (3-275:4-285)
10 20 30 40 50
pF1KE6 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMW
..:::: .: . ::: :..:: : .:.:::. ::..::::::::::::.:.:..:::
CCDS32 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFILLFYLVFYGFLTAMFTLTMW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPY--
:::::..:..:::.:.. .::::. :: . :. . :: :. ... :.:::.::
CCDS32 VMLQTVSDHTPKYQDRLATPGLMIRPK-TENLDVIVNVSDTESWDQHVQKLNKFLEPYND
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TLEEQKNLTVCPDGALFEQ--KGPVYV---ACQFPISLLQACSGMNDPD-FGYSQGNPCI
... ::: :: : .:: .: . :::: . : :::..: .::: :.::.
CCDS32 SIQAQKN-DVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCSGIGDSTHYGYSTGQPCV
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 LVKMNRIIGLKPEGVPRID--CVSKN----EDIPNVAVYPHNGMIDLKYFPYYGKKLHVG
..::::.:.. . .. :..: :.. : ...: :: ::: ::::::::.::.
CCDS32 FIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANGNIDLMYFPYYGKKFHVN
180 190 200 210 220 230
230 240 250 260 270
pF1KE6 YLQPLVAVQ-VSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
: ::::::. .. .:: ::.:::.:. .::. ..:.:::: ::: ::.
CCDS32 YTQPLVAVKFLNVTPNV---EVNVECRIN-AANIATDDERDKFAGRVAFKLRINKT
240 250 260 270 280 290
>>CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 (291 aa)
initn: 580 init1: 237 opt: 457 Z-score: 564.7 bits: 112.4 E(32554): 3.9e-25
Smith-Waterman score: 632; 35.4% identity (67.0% similar) in 285 aa overlap (5-275:6-287)
10 20 30 40 50
pF1KE6 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMW
:::. .: . :.. . .:: ::..:::: . : : :.:..:: ...::.. ..
CCDS95 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCLY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VMLQTLNDEVPKYRDQIPSPGLMVFPKPV--TALEYTFSRSDPTSYAGYIEDLKKFLKPY
:..::.. .: :.::. :::. . : .:: ... :: ..: . :. :: :
CCDS95 VLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVSDNRTWADLTQTLHAFLAGY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 TLEEQKNLTVCPDGALFEQ---KGPVYV--ACQFPISLLQACSGMNDPDFGYSQGNPCIL
. :.. : . : : ..: .. .:.: ..:: :::. ::.::. .:.::..
CCDS95 SPAAQEDSINCTSEQYFFQESFRAPNHTKFSCKFTADMLQNCSGLADPNFGFEEGKPCFI
130 140 150 160 170 180
180 190 200 210 220
pF1KE6 VKMNRIIGLKPEG--VPRIDC--VSKNEDI--P-NVAVYPHNGMIDLKYFPYYGKKLHVG
.:::::. . : . .::.:: ... ... : .: :: :: ..:.:::::::: .
CCDS95 IKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYPPNGTFSLHYFPYYGKKAQPH
190 200 210 220 230 240
230 240 250 260 270
pF1KE6 YLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
: .::::... : :. ::.. ::. . .. .. .: . :.: ::.
CCDS95 YSNPLVAAKLLNIPRNA--EVAIVCKV-MAEHVTFNNPHDPYEGKVEFKLKIEK
250 260 270 280 290
>>CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 (303 aa)
initn: 580 init1: 241 opt: 317 Z-score: 392.8 bits: 80.6 E(32554): 1.5e-15
Smith-Waterman score: 603; 36.6% identity (60.4% similar) in 298 aa overlap (16-279:12-303)
10 20 30 40 50 60
pF1KE6 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWV
:: ::.: ::::::. :: :::::..::: ::..: :. :
CCDS12 MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 MLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLE
:: :... : :.:.. ::: .:. . : .: .:: :: .:. .. .::. :
CCDS12 MLLTISEFKPTYQDRVAPPGLTQIPQ-IQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDS
60 70 80 90 100 110
130 140 150 160
pF1KE6 EQKNLTV---CPD--------GALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNP
:.. . : : : . ...: : :.: . : :::.:: .::..:.:
CCDS12 AQRDDMIFEDCGDVPSEPKERGDFNHERGERKV-CRFKLEWLGNCSGLNDETYGYKEGKP
120 130 140 150 160 170
170 180 190 200
pF1KE6 CILVKMNRIIGLKP--------EGVPR---------IDCVSK-NEDIPNVAVYPHNGM--
::..:.::..:.:: : : ..:..: .:: .:. . :.
CCDS12 CIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKVGNVEYFGLGN
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE6 ---IDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDK
. :.:.::::: :. :::::.::: :. . :. .::: : :. . ...:.
CCDS12 SPGFPLQYYPYYGKLLQPKYLQPLLAVQ--FTNLTMDTEIRIECKAYGE-NI-GYSEKDR
240 250 260 270 280 290
270
pF1KE6 FLGRVMFKITARA
: :: :: ...
CCDS12 FQGRFDVKIEVKS
300
279 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:47:08 2016 done: Tue Nov 8 11:47:08 2016
Total Scan time: 1.880 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]