Result of FASTA (ccds) for
pFN21AE6281
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6281, 252 aa
1>>>pF1KE6281 252 - 252 aa - 252 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7045+/-0.000729; mu= 17.7602+/- 0.044
mean_var=64.3742+/-12.700, 0's: 0 Z-trim(109.4): 34 B-trim: 884 in 2/48
Lambda= 0.159852
statistics sampled from 10802 (10836) to 10802 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.333), width: 16
Scan time: 1.900
The best scores are: opt bits E(32554)
CCDS12510.1 SPINT2 gene_id:10653|Hs108|chr19 ( 252) 1722 405.4 1.9e-113
CCDS54261.1 SPINT2 gene_id:10653|Hs108|chr19 ( 195) 1087 258.9 1.9e-69
CCDS44773.1 APLP2 gene_id:334|Hs108|chr11 ( 751) 277 72.6 8.9e-13
CCDS58196.1 APLP2 gene_id:334|Hs108|chr11 ( 761) 277 72.6 9e-13
CCDS8486.1 APLP2 gene_id:334|Hs108|chr11 ( 763) 277 72.6 9e-13
CCDS10067.1 SPINT1 gene_id:6692|Hs108|chr15 ( 529) 273 71.5 1.3e-12
CCDS45231.1 SPINT1 gene_id:6692|Hs108|chr15 ( 513) 259 68.3 1.2e-11
>>CCDS12510.1 SPINT2 gene_id:10653|Hs108|chr19 (252 aa)
initn: 1722 init1: 1722 opt: 1722 Z-score: 2150.3 bits: 405.4 E(32554): 1.9e-113
Smith-Waterman score: 1722; 99.6% identity (100.0% similar) in 252 aa overlap (1-252:1-252)
10 20 30 40 50 60
pF1KE6 MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 DHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LRCFRQQENPPLPLGSKVVLLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGD
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
CCDS12 LRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGD
190 200 210 220 230 240
250
pF1KE6 DKEQLVKNTYVL
::::::::::::
CCDS12 DKEQLVKNTYVL
250
>>CCDS54261.1 SPINT2 gene_id:10653|Hs108|chr19 (195 aa)
initn: 1087 init1: 1087 opt: 1087 Z-score: 1360.3 bits: 258.9 E(32554): 1.9e-69
Smith-Waterman score: 1177; 77.0% identity (77.4% similar) in 252 aa overlap (1-252:1-195)
10 20 30 40 50 60
pF1KE6 MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTD
:::::::::::::::::::::::::::::::::::
CCDS54 MAQLCGLRRSRAFLALLGSLLLSGVLAADRERSIH-------------------------
10 20 30
70 80 90 100 110 120
pF1KE6 GSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSE
::::::::::::::::::::::::::::
CCDS54 --------------------------------ENATGDLATSRNAADSSVPSAPRRQDSE
40 50 60
130 140 150 160 170 180
pF1KE6 DHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACM
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE6 LRCFRQQENPPLPLGSKVVLLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGD
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
CCDS54 LRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGD
130 140 150 160 170 180
250
pF1KE6 DKEQLVKNTYVL
::::::::::::
CCDS54 DKEQLVKNTYVL
190
>>CCDS44773.1 APLP2 gene_id:334|Hs108|chr11 (751 aa)
initn: 262 init1: 262 opt: 277 Z-score: 342.9 bits: 72.6 E(32554): 8.9e-13
Smith-Waterman score: 277; 31.2% identity (59.6% similar) in 141 aa overlap (59-199:242-374)
30 40 50 60 70 80
pF1KE6 DRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC
:... . :. .. : .... :: ..
CCDS44 VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDR
220 230 240 250 260 270
90 100 110 120 130 140
pF1KE6 ATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPR
.. :: . .: :. : . . . . . . :. .:.:::::: .::
CCDS44 DYYYDTFKGDDYNEEN------PTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPR
280 290 300 310 320
150 160 170 180 190 200
pF1KE6 WYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVLLAGLFVMV
::::. ...: :::::: ::.:...::. :: : . :: :: .. :
CCDS44 WYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC--KAMIPPTPLPTNDVDVYFETSAD
330 340 350 360 370 380
210 220 230 240 250
pF1KE6 LILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL
CCDS44 DNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEK
390 400 410 420 430 440
>>CCDS58196.1 APLP2 gene_id:334|Hs108|chr11 (761 aa)
initn: 262 init1: 262 opt: 277 Z-score: 342.8 bits: 72.6 E(32554): 9e-13
Smith-Waterman score: 277; 31.2% identity (59.6% similar) in 141 aa overlap (59-199:252-384)
30 40 50 60 70 80
pF1KE6 DRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC
:... . :. .. : .... :: ..
CCDS58 VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDR
230 240 250 260 270 280
90 100 110 120 130 140
pF1KE6 ATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPR
.. :: . .: :. : . . . . . . :. .:.:::::: .::
CCDS58 DYYYDTFKGDDYNEEN------PTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPR
290 300 310 320 330
150 160 170 180 190 200
pF1KE6 WYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVLLAGLFVMV
::::. ...: :::::: ::.:...::. :: : . :: :: .. :
CCDS58 WYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC--KAMIPPTPLPTNDVDVYFETSAD
340 350 360 370 380 390
210 220 230 240 250
pF1KE6 LILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL
CCDS58 DNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEK
400 410 420 430 440 450
>>CCDS8486.1 APLP2 gene_id:334|Hs108|chr11 (763 aa)
initn: 262 init1: 262 opt: 277 Z-score: 342.8 bits: 72.6 E(32554): 9e-13
Smith-Waterman score: 277; 31.2% identity (59.6% similar) in 141 aa overlap (59-199:242-374)
30 40 50 60 70 80
pF1KE6 DRERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC
:... . :. .. : .... :: ..
CCDS84 VSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDR
220 230 240 250 260 270
90 100 110 120 130 140
pF1KE6 ATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPR
.. :: . .: :. : . . . . . . :. .:.:::::: .::
CCDS84 DYYYDTFKGDDYNEEN------PTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPR
280 290 300 310 320
150 160 170 180 190 200
pF1KE6 WYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVLLAGLFVMV
::::. ...: :::::: ::.:...::. :: : . :: :: .. :
CCDS84 WYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC--KAMIPPTPLPTNDVDVYFETSAD
330 340 350 360 370 380
210 220 230 240 250
pF1KE6 LILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL
CCDS84 DNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEK
390 400 410 420 430 440
>>CCDS10067.1 SPINT1 gene_id:6692|Hs108|chr15 (529 aa)
initn: 416 init1: 245 opt: 273 Z-score: 339.9 bits: 71.5 E(32554): 1.3e-12
Smith-Waterman score: 383; 31.0% identity (55.0% similar) in 242 aa overlap (32-219:244-485)
10 20 30 40 50 60
pF1KE6 AQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDG
.. .:.::.:. :::::.:.:::.:. :.
CCDS10 KEGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQ
220 230 240 250 260 270
70 80 90 100
pF1KE6 SCQLFVYGGCDGNSNNYLTKEECLKKCATVT----ENATGDLAT--------SRNAA---
:. :::::: ::.:::: .:::. : : ....: :: :. .
CCDS10 ICKSFVYGGCLGNKNNYLREEECILACRGVQGGPLRGSSGAQATFPQGPSMERRHPVCSG
280 290 300 310 320 330
110 120 130
pF1KE6 ---------------DS-----SVPSAPRRQDS---EDHSSDM-------FNYEE-YCTA
:: ..:. : .: : ..: . : .. .:.
CCDS10 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVD
340 350 360 370 380 390
140 150 160 170 180
pF1KE6 NAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--------FRQQ
:: :. :.::::.. . : : :::: ::::... :. :. : : .
CCDS10 LPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLR
400 410 420 430 440 450
190 200 210 220 230 240
pF1KE6 ENPPLPLGSKVVLLAGLFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVK
.. :.: ..: . ...:... :. . : . :
CCDS10 REIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFHGHHHHPPPTPASSTVST
460 470 480 490 500 510
250
pF1KE6 NTYVL
CCDS10 TEDTEHLVYNHTTRPL
520
>>CCDS45231.1 SPINT1 gene_id:6692|Hs108|chr15 (513 aa)
initn: 430 init1: 259 opt: 259 Z-score: 322.7 bits: 68.3 E(32554): 1.2e-11
Smith-Waterman score: 404; 32.3% identity (56.6% similar) in 226 aa overlap (32-219:244-469)
10 20 30 40 50 60
pF1KE6 AQLCGLRRSRAFLALLGSLLLSGVLAADRERSIHDFCLVSKVVGRCRASMPRWWYNVTDG
.. .:.::.:. :::::.:.:::.:. :.
CCDS45 KEGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQ
220 230 240 250 260 270
70 80 90 100
pF1KE6 SCQLFVYGGCDGNSNNYLTKEECLKKCATV--------------TENATGDLATSRNAAD
:. :::::: ::.:::: .:::. : : : . : .. :
CCDS45 ICKSFVYGGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCID
280 290 300 310 320 330
110 120 130 140 150
pF1KE6 S-----SVPSAPRRQDS---EDHSSDM-------FNYEE-YCTANAVTGPCRASFPRWYF
: ..:. : .: : ..: . : .. .:. :: :. :.::::.
CCDS45 SFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYY
340 350 360 370 380 390
160 170 180 190 200
pF1KE6 DVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--------FRQQENPPLPLGSKVVLLAG
. . : : :::: ::::... :. :. : : ... :.: ..: . ..
CCDS45 NPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVA
400 410 420 430 440 450
210 220 230 240 250
pF1KE6 LFVMVLILFLGASMVYLIRVARRNQERALRTVWSSGDDKEQLVKNTYVL
.:... :. . : . :
CCDS45 VFLVICIVVVVAILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
460 470 480 490 500 510
252 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:44:41 2016 done: Tue Nov 8 11:44:41 2016
Total Scan time: 1.900 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]