Result of FASTA (ccds) for
pFN21AE6262
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6262, 278 aa
1>>>pF1KE6262 278 - 278 aa - 278 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5983+/-0.000753; mu= 13.7163+/- 0.045
mean_var=64.3749+/-13.091, 0's: 0 Z-trim(108.5): 22 B-trim: 71 in 1/48
Lambda= 0.159851
statistics sampled from 10220 (10239) to 10220 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.315), width: 16
Scan time: 1.720
The best scores are: opt bits E(32554)
CCDS6178.1 TTPA gene_id:7274|Hs108|chr8 ( 278) 1860 437.3 5.9e-123
CCDS13332.2 TTPAL gene_id:79183|Hs108|chr20 ( 342) 563 138.2 7.8e-33
CCDS6176.1 CLVS1 gene_id:157807|Hs108|chr8 ( 354) 481 119.3 4e-27
CCDS34525.1 CLVS2 gene_id:134829|Hs108|chr6 ( 327) 480 119.0 4.4e-27
CCDS32324.1 RLBP1 gene_id:6017|Hs108|chr15 ( 317) 441 110.0 2.2e-24
CCDS10280.1 PTPN9 gene_id:5780|Hs108|chr15 ( 593) 310 79.9 4.7e-15
>>CCDS6178.1 TTPA gene_id:7274|Hs108|chr8 (278 aa)
initn: 1860 init1: 1860 opt: 1860 Z-score: 2320.9 bits: 437.3 E(32554): 5.9e-123
Smith-Waterman score: 1860; 100.0% identity (100.0% similar) in 278 aa overlap (1-278:1-278)
10 20 30 40 50 60
pF1KE6 MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 FDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 HWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 AVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 AVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFPDI
190 200 210 220 230 240
250 260 270
pF1KE6 LPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
::::::::::::::::::::::::::::::::::::::
CCDS61 LPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
250 260 270
>>CCDS13332.2 TTPAL gene_id:79183|Hs108|chr20 (342 aa)
initn: 527 init1: 527 opt: 563 Z-score: 702.9 bits: 138.2 E(32554): 7.8e-33
Smith-Waterman score: 563; 39.2% identity (65.8% similar) in 240 aa overlap (30-268:60-295)
10 20 30 40 50
pF1KE6 MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRAR
::: .:. : : :.:::::::::
CCDS13 GYVCSLTEDLVTKAREELQEKPEWRLRDVQALRDMVRKE-YPNLSTSLDDAFLLRFLRAR
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE6 DFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRI
:: : : .:: ::.. : ::. .:.: .. .: .:. :: :: : .:. :
CCDS13 KFDYDRALQLLVNYHSCRRSWPEVFNNLKPSALKDVLASGFLTVLPHTDPRGCHVVCIRP
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE6 AHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKI
.: :. . . .:. .: : ..: ::: ::: . : .: ..:.: .. : .:::.
CCDS13 DRWIPSNYPITENIRAIYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKV
150 160 170 180 190 200
180 190 200 210 220 230
pF1KE6 AAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHFP-
..: :.::......:..::: ::...:..::::: ::: .:. .::.. . :: ..:
CCDS13 IGILQDGFPIRIKAVHVVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLN-SLHTNLPR
210 220 230 240 250 260
240 250 260 270
pF1KE6 DILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
.::: :::: .. :. .. :::
CCDS13 SILPKEYGGTAGELDTAT--WNAVLLASEDDFVKEFCQPVPACDSILGQTLLPEGLTSDA
270 280 290 300 310 320
>>CCDS6176.1 CLVS1 gene_id:157807|Hs108|chr8 (354 aa)
initn: 491 init1: 399 opt: 481 Z-score: 600.5 bits: 119.3 E(32554): 4e-27
Smith-Waterman score: 481; 38.4% identity (69.0% similar) in 203 aa overlap (49-247:73-273)
20 30 40 50 60 70
pF1KE6 DHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRA
:.:.::::::: : :.::: .:...:
CCDS61 NENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQ
50 60 70 80 90 100
80 90 100 110 120 130
pF1KE6 ECPEISADLHPRSIIGLLKA---GYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRV
.. ... . :. .: :. :::..:: : :.:. :.:: . . :..:.
CCDS61 LNLDMFKNFKADDP-GIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRA
110 120 130 140 150 160
140 150 160 170 180 190
pF1KE6 SLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIH
:.. :..... : : ::. :.: ...:..: ..:::. : : :::: . :.:
CCDS61 ILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVH
170 180 190 200 210 220
200 210 220 230 240 250
pF1KE6 LINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHF-PDILPLEYGGEEFSMED
..:.: .::....::::: .: ..:: .:::: . :: : . :..:: :.::
CCDS61 FVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLN-SLHQLIHPEFLPSEFGGTLPPYDM
230 240 250 260 270 280
260 270
pF1KE6 ICQEWTNFIMKSEDYLSSISESIQ
CCDS61 GTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEE
290 300 310 320 330 340
>>CCDS34525.1 CLVS2 gene_id:134829|Hs108|chr6 (327 aa)
initn: 419 init1: 349 opt: 480 Z-score: 599.8 bits: 119.0 E(32554): 4.4e-27
Smith-Waterman score: 480; 39.1% identity (67.3% similar) in 202 aa overlap (49-247:51-251)
20 30 40 50 60 70
pF1KE6 DHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRA
:.:.::::::: : :.::: .:...:
CCDS34 NENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQ
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE6 ECPEISADLHPRS--IIGLLKAGYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRVS
. .. ... . : :: :. : : . : : :.:. :.:: . .: :..:.
CCDS34 QNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAI
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE6 LITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIHL
:.. : .... : : ::. :.: .. :..: ..:::. . : :::: . :::.
CCDS34 LLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHF
150 160 170 180 190 200
200 210 220 230 240 250
pF1KE6 INEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHF-PDILPLEYGGEEFSMEDI
.:.: .::....:.::: :: ..:: .:::: . :: : . :.::: :.::
CCDS34 VNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLN-SLHQLIHPEILPSEFGGMLPPYDMG
210 220 230 240 250
260 270
pF1KE6 CQEWTNFIMKSEDYLSSISESIQ
CCDS34 TWARTLLDHEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEEN
260 270 280 290 300 310
>>CCDS32324.1 RLBP1 gene_id:6017|Hs108|chr15 (317 aa)
initn: 437 init1: 437 opt: 441 Z-score: 551.4 bits: 110.0 E(32554): 2.2e-24
Smith-Waterman score: 441; 32.7% identity (66.8% similar) in 226 aa overlap (24-247:66-291)
10 20 30 40 50
pF1KE6 MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAP-LPLTDS-F
:: . : ..: .: .: . :: :
CCDS32 PCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGF
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE6 LLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTG
.:::.::: :.. :..::..: ..: . ::. .: :... ..::: ::: ::: :
CCDS32 FLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYG
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE6 SKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQI
:... : .:. . .: ..... . : .... ::: ::. : ...:. ...: ..
CCDS32 RVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASL
160 170 180 190 200 210
180 190 200 210 220 230
pF1KE6 TPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQ
: .:.. .: :::: . ..::.:..: : ......:::: :. ::. .::.. .
CCDS32 RTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSG
220 230 240 250 260 270
240 250 260 270
pF1KE6 SLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
. .::: ..::
CCDS32 FYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF
280 290 300 310
>>CCDS10280.1 PTPN9 gene_id:5780|Hs108|chr15 (593 aa)
initn: 267 init1: 167 opt: 310 Z-score: 383.7 bits: 79.9 E(32554): 4.7e-15
Smith-Waterman score: 310; 25.1% identity (60.1% similar) in 243 aa overlap (7-247:2-237)
10 20 30 40 50 60
pF1KE6 MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARD
.:...:. . :. .: . . . .. . : ::. . ..:: ::
CCDS10 MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARK
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 FDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTGSKVLIYRIA
::. : .:...: . : . .. : . . . . .: .: :::::... ..
CCDS10 FDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTAR
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 HWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIA
:. . . :... . . :. ::::::. :.:. : .... :.. ...::.
CCDS10 LHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYAN-FEL--DLGKKVL
120 130 140 150 160 170
190 200 210 220 230
pF1KE6 AVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQS-LLQHFP-
.: .:: ... . ... :. :.. .:.:. .: .:..:::.. : : . ::.:
CCDS10 NLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQI----LKTSEVTQHLPR
180 190 200 210 220
240 250 260 270
pF1KE6 DILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
. :: . ::
CCDS10 ECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTI
230 240 250 260 270 280
278 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:35:10 2016 done: Tue Nov 8 11:35:10 2016
Total Scan time: 1.720 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]