Result of FASTA (ccds) for
pFN21AE6250
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6250, 258 aa
1>>>pF1KE6250 258 - 258 aa - 258 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1341+/-0.000712; mu= 12.8148+/- 0.043
mean_var=107.3503+/-21.634, 0's: 0 Z-trim(112.8): 51 B-trim: 0 in 0/53
Lambda= 0.123786
statistics sampled from 13481 (13532) to 13481 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.758), E-opt: 0.2 (0.416), width: 16
Scan time: 1.910
The best scores are: opt bits E(32554)
CCDS1229.2 MPZ gene_id:4359|Hs108|chr1 ( 248) 1665 307.1 7.5e-84
CCDS1264.1 MPZL1 gene_id:9019|Hs108|chr1 ( 269) 427 86.0 2.9e-17
CCDS44273.1 MPZL1 gene_id:9019|Hs108|chr1 ( 209) 420 84.7 5.7e-17
CCDS8392.1 MPZL3 gene_id:196264|Hs108|chr11 ( 235) 366 75.1 4.9e-14
CCDS66241.1 MPZL3 gene_id:196264|Hs108|chr11 ( 223) 355 73.1 1.9e-13
CCDS8393.1 MPZL2 gene_id:10205|Hs108|chr11 ( 215) 349 72.0 3.8e-13
>>CCDS1229.2 MPZ gene_id:4359|Hs108|chr1 (248 aa)
initn: 1665 init1: 1665 opt: 1665 Z-score: 1618.8 bits: 307.1 E(32554): 7.5e-84
Smith-Waterman score: 1665; 100.0% identity (100.0% similar) in 248 aa overlap (11-258:1-248)
10 20 30 40 50 60
pF1KE6 MLRAPAPAPAMAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHC
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHC
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 SFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 LLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRSTK
180 190 200 210 220 230
250
pF1KE6 AVSEKKAKGLGESRKDKK
::::::::::::::::::
CCDS12 AVSEKKAKGLGESRKDKK
240
>>CCDS1264.1 MPZL1 gene_id:9019|Hs108|chr1 (269 aa)
initn: 494 init1: 382 opt: 427 Z-score: 423.5 bits: 86.0 E(32554): 2.9e-17
Smith-Waterman score: 456; 36.8% identity (65.6% similar) in 250 aa overlap (2-236:1-247)
10 20 30 40 50
pF1KE6 MLRAPAPAPAMAPGAPSSSPS--PILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTL
. : : : :. .::.: .::. : .:. . ..:. ::: .:. : :.. :
CCDS12 MAASAGAGAVI-AAPDSRRWLWSVLAAAL--GLLTAGVSALEVYTPKEIFVANGTQGKL
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 HCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWK
:.: :. .. : .: .::::. ..:.:::..:: :. . ::.::.:.:: :
CCDS12 TCKFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 DGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEK--VPTR-YGVVLGAVIGGV
:.:: :.:... :::. :::::::::: . ... ::: :: .:. ::.: : . :
CCDS12 DASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVV
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 LGVVLLLLLLFYVV-RYCWLRRQ---AALQRRLSAMEKGKLHKPG------KDASKRGRQ
::..::. ... :. : .:. . .. :: .... ..:. :. . ..:
CCDS12 LGLTLLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQ
180 190 200 210 220 230
230 240 250
pF1KE6 TPVLYAMLDHSRSTKAVSEKKAKGLGESRKDKK
::.::.::::
CCDS12 GPVIYAQLDHSGGHHSDKINKSESVVYADIRKN
240 250 260
>>CCDS44273.1 MPZL1 gene_id:9019|Hs108|chr1 (209 aa)
initn: 445 init1: 382 opt: 420 Z-score: 418.2 bits: 84.7 E(32554): 5.7e-17
Smith-Waterman score: 420; 39.9% identity (67.9% similar) in 193 aa overlap (2-189:1-190)
10 20 30 40 50
pF1KE6 MLRAPAPAPAMAPGAPSSSPS--PILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTL
. : : : :. .::.: .::. : .:. . ..:. ::: .:. : :.. :
CCDS44 MAASAGAGAVI-AAPDSRRWLWSVLAAAL--GLLTAGVSALEVYTPKEIFVANGTQGKL
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 HCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWK
:.: :. .. : .: .::::. ..:.:::..:: :. . ::.::.:.:: :
CCDS44 TCKFKSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 DGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEK--VPTR-YGVVLGAVIGGV
:.:: :.:... :::. :::::::::: . ... ::: :: .:. ::.: : . :
CCDS44 DASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVVEKENLPVFPVWVVVGIVTAVV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LGVVLLLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDH
::..::. ... :.
CCDS44 LGLTLLISMILAVLYRRKNSKRDYTGAQSYMHS
180 190 200
>>CCDS8392.1 MPZL3 gene_id:196264|Hs108|chr11 (235 aa)
initn: 271 init1: 179 opt: 366 Z-score: 365.4 bits: 75.1 E(32554): 4.9e-14
Smith-Waterman score: 366; 33.7% identity (67.9% similar) in 196 aa overlap (12-203:6-191)
10 20 30 40 50 60
pF1KE6 MLRAPAPAPAMAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHC
: :. . . :.:.::.:... . . .. . .: .:.: :: .. :.:
CCDS83 MQQRGAAGSRGCALFPLLGVLFFQGVYI--VFSLEIRADAHVRGYVGEKIKLKC
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 SFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDG
.: :. :.: ... : :.: .. ..::::: . : : .:::..::.:::. :.
CCDS83 TFKSTSDVTDKLTIDWTYRPPSSSHTVSIFHYQSFQ-YPTTAGTFRDRISWVGNVYKGDA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVL
:: : : .:::::.: ::::::. . .. : : :. .:..:..: ..:....
CCDS83 SISISNPTIKDNGTFSCAVKNPPDVHHNIPMTELTVTER---GFGTMLSSV--ALLSILV
120 130 140 150 160
190 200 210 220 230
pF1KE6 LL----LLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHS
.. .. . .::. :. :.:..:
CCDS83 FVPSAVVVALLLVRMG--RKAAGLKKRSRSGYKKSSIEVSDDTDQEEEEACMARLCVRCA
170 180 190 200 210 220
>>CCDS66241.1 MPZL3 gene_id:196264|Hs108|chr11 (223 aa)
initn: 271 init1: 179 opt: 355 Z-score: 355.1 bits: 73.1 E(32554): 1.9e-13
Smith-Waterman score: 355; 35.1% identity (67.2% similar) in 174 aa overlap (34-203:14-179)
10 20 30 40 50 60
pF1KE6 APAPAPAMAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFW
: : ... . : .:.: :: .. :.:.:
CCDS66 MQQRGAAGSRGCALFPLLGVLFFQDAHVRGYVGEKIKLKCTFK
10 20 30 40
70 80 90 100 110 120
pF1KE6 SSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIV
:. :.: ... : :.: .. ..::::: . : : .:::..::.:::. :.::
CCDS66 STSDVTDKLTIDWTYRPPSSSHTVSIFHYQSFQ-YPTTAGTFRDRISWVGNVYKGDASIS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 IHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGVLGVVLLL-
: : .:::::.: ::::::. . .. : : :. .:..:..: ..:......
CCDS66 ISNPTIKDNGTFSCAVKNPPDVHHNIPMTELTVTER---GFGTMLSSV--ALLSILVFVP
110 120 130 140 150
190 200 210 220 230
pF1KE6 ---LLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRST
.. . .::. :. :.:..:
CCDS66 SAVVVALLLVRMG--RKAAGLKKRSRSGYKKSSIEVSDDTDQEEEEACMARLCVRCAECL
160 170 180 190 200 210
>>CCDS8393.1 MPZL2 gene_id:10205|Hs108|chr11 (215 aa)
initn: 229 init1: 203 opt: 349 Z-score: 349.5 bits: 72.0 E(32554): 3.8e-13
Smith-Waterman score: 349; 31.6% identity (65.8% similar) in 193 aa overlap (18-208:5-192)
10 20 30 40 50 60
pF1KE6 MLRAPAPAPAMAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHC
:: .: .: .. .: : :. .::.: .... :. . :.:
CCDS83 MYGKSSTRAVLLLLGIQLTALWPIAAVEIYTSRVLEAVNGTDARLKC
10 20 30 40
70 80 90 100 110 120
pF1KE6 SFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDG
.: : :.: .. :: ..: : .:.: . .:. : ::.:..: :.:. :.
CCDS83 TFSSFAPVGDALTVTWNFRPLDGGPEQFVFYY-HIDPFQPMSGRFKDRVSWDGNPERYDA
50 60 70 80 90 100
130 140 150 160 170
pF1KE6 SIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKVPTRYGVV--LGAVIGGVLGV
::.. .:...::::.::.::::::. : ... : : . : :.. . :. .::..
CCDS83 SILLWKLQFDDNGTYTCQVKNPPDVDGVIGEIRLSVVHTV--RFSEIHFLALAIGSA--C
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 VLLLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKDASKRGRQTPVLYAMLDHSRS
.:...... :: . :.. .: ...:
CCDS83 ALMIIIVIVVVLFQHYRKKRWAERAHKVVEIKSKEEERLNQEKKVSVYLEDTD
170 180 190 200 210
258 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:27:52 2016 done: Tue Nov 8 11:27:52 2016
Total Scan time: 1.910 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]