Result of FASTA (omim) for
pFN21AE6240
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6240, 195 aa
1>>>pF1KE6240 195 - 195 aa - 195 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2196+/-0.000246; mu= 14.3382+/- 0.016
mean_var=66.0454+/-13.059, 0's: 0 Z-trim(121.8): 26 B-trim: 0 in 0/56
Lambda= 0.157817
statistics sampled from 38890 (38917) to 38890 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.81), E-opt: 0.2 (0.456), width: 16
Scan time: 4.270
The best scores are: opt bits E(85289)
NP_006658 (OMIM: 300435) membrane-associated proge ( 195) 1314 306.8 1.4e-83
NP_001269550 (OMIM: 300435) membrane-associated pr ( 143) 744 177.0 1.3e-44
NP_006311 (OMIM: 607735) membrane-associated proge ( 247) 664 158.9 6.1e-39
XP_011529835 (OMIM: 607735) PREDICTED: membrane-as ( 217) 262 67.3 1.9e-11
NP_037481 (OMIM: 611874) neudesin precursor [Homo ( 172) 233 60.7 1.6e-09
>>NP_006658 (OMIM: 300435) membrane-associated progester (195 aa)
initn: 1314 init1: 1314 opt: 1314 Z-score: 1621.5 bits: 306.8 E(85289): 1.4e-83
Smith-Waterman score: 1314; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KE6 MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVY
130 140 150 160 170 180
190
pF1KE6 SDEEEPKDESARKND
:::::::::::::::
NP_006 SDEEEPKDESARKND
190
>>NP_001269550 (OMIM: 300435) membrane-associated proges (143 aa)
initn: 944 init1: 736 opt: 744 Z-score: 922.1 bits: 177.0 E(85289): 1.3e-44
Smith-Waterman score: 843; 72.8% identity (72.8% similar) in 195 aa overlap (1-195:1-143)
10 20 30 40 50 60
pF1KE6 MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRD
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPPPLPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGP-----------
70 80 90 100
130 140 150 160 170 180
pF1KE6 ASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGEEPTVY
::::::::::::::::::
NP_001 -----------------------------------------VKYHHVGKLLKEGEEPTVY
110 120
190
pF1KE6 SDEEEPKDESARKND
:::::::::::::::
NP_001 SDEEEPKDESARKND
130 140
>>NP_006311 (OMIM: 607735) membrane-associated progester (247 aa)
initn: 636 init1: 636 opt: 664 Z-score: 820.1 bits: 158.9 E(85289): 6.1e-39
Smith-Waterman score: 664; 59.4% identity (82.4% similar) in 165 aa overlap (30-190:80-244)
10 20 30 40 50
pF1KE6 MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKI-VR-GDQPAASGDS
::. :..: .. :.. :: : . ..: .
NP_006 ESPGDAGAAAEGGGWAAAALALLTGGGEMLLNVALVALVLLGAYRLWVRWGRRGLGAGAG
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE6 DDDEPPP--LPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGV
.: : :::.:.:::. .::..:: ..::::.:.:::::::::: ::::: ::::.
NP_006 AGEESPATSLPRMKKRDFSLEQLRQYDGSRNPRILLAVNGKVFDVTKGSKFYGPAGPYGI
110 120 130 140 150 160
120 130 140 150 160 170
pF1KE6 FAGRDASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGE
:::::::::::::::::.::.:::::::::.:.:.:.. .:: :: :: .::.::: ::
NP_006 FAGRDASRGLATFCLDKDALRDEYDDLSDLNAVQMESVREWEMQFKEKYDYVGRLLKPGE
170 180 190 200 210 220
180 190
pF1KE6 EPTVYSDEEEPKDESARKND
::. :.:::. ::..
NP_006 EPSEYTDEEDTKDHNKQD
230 240
>>XP_011529835 (OMIM: 607735) PREDICTED: membrane-associ (217 aa)
initn: 246 init1: 246 opt: 262 Z-score: 326.3 bits: 67.3 E(85289): 1.9e-11
Smith-Waterman score: 262; 50.0% identity (76.2% similar) in 84 aa overlap (30-109:80-163)
10 20 30 40 50
pF1KE6 MAAEDVVATGADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKI-VR-GDQPAASGDS
::. :..: .. :.. :: : . ..: .
XP_011 ESPGDAGAAAEGGGWAAAALALLTGGGEMLLNVALVALVLLGAYRLWVRWGRRGLGAGAG
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE6 DDDEPPP--LPRLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTKGRKFYGPEGPYGV
.: : :::.:.:::. .::..:: ..::::.:.:::::::::: :::::
XP_011 AGEESPATSLPRMKKRDFSLEQLRQYDGSRNPRILLAVNGKVFDVTKGSKFYGPGEELEG
110 120 130 140 150 160
120 130 140 150 160 170
pF1KE6 FAGRDASRGLATFCLDKEALKDEYDDLSDLTAAQQETLSDWESQFTFKYHHVGKLLKEGE
XP_011 EGKDPLQLKHNPLRTGRPLGTGPRLGACKVPTLQSLKSRRISNTSDSL
170 180 190 200 210
>>NP_037481 (OMIM: 611874) neudesin precursor [Homo sapi (172 aa)
initn: 163 init1: 138 opt: 233 Z-score: 292.1 bits: 60.7 E(85289): 1.6e-09
Smith-Waterman score: 233; 33.3% identity (60.5% similar) in 162 aa overlap (41-189:18-171)
20 30 40 50 60
pF1KE6 ADPSDLESGGLLHEIFTSPLNLLLLGLCIFLLYKIVRGDQPAASGDSDD--DEPPPLPRL
:. .. : : .:.. .. ::.
NP_037 MVGPAPRRRLRPLAALALVLALAPGLPTARAGQTPRPAERGPPV---
10 20 30 40
70 80 90 100 110 120
pF1KE6 KRRDFTPAELRRFDGVQ-DPRILMAINGKVFDVTKGRKFYGPEGPYGVFAGRDASRGLAT
: :: :: :. : . : : .:..: :::::.:..::: .::....:.:..::.:
NP_037 --RLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE6 FCLDKEALKDEYDDLSDLTAAQQETLSDWESQ-FTFKYHHVG----KLLKEGEEPTV-YS
. :: : : . ::: . :.:.. .. . :: :: ..:.: :.. ..
NP_037 MSLDPA---DLTHDTTGLTAKELEALDEVFTKVYKAKYPIVGYTARRILNEDGSPNLDFK
110 120 130 140 150
190
pF1KE6 DEEEP----KDESARKND
:..: :::
NP_037 PEDQPHFDIKDEF
160 170
195 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:22:19 2016 done: Tue Nov 8 11:22:20 2016
Total Scan time: 4.270 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]