FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6237, 240 aa
  1>>>pF1KE6237 240 - 240 aa - 240 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2155+/-0.000294; mu= 15.6855+/- 0.018
 mean_var=78.1659+/-15.690, 0's: 0 Z-trim(118.6): 5  B-trim: 10 in 1/54
 Lambda= 0.145066
 statistics sampled from 31791 (31795) to 31791 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.373), width:  16
 Scan time:  6.280

The best scores are:                                      opt bits E(85289)
NP_003093 (OMIM: 185490) extracellular superoxide  ( 240) 1662 356.6 2.2e-98
NP_000445 (OMIM: 105400,147450) superoxide dismuta ( 154)  355 82.9 3.4e-16
NP_005116 (OMIM: 603864) copper chaperone for supe ( 274)  292 70.0 4.9e-12


>>NP_003093 (OMIM: 185490) extracellular superoxide dism  (240 aa)
 initn: 1662 init1: 1662 opt: 1662  Z-score: 1887.5  bits: 356.6 E(85289): 2.2e-98
Smith-Waterman score: 1662; 99.6% identity (100.0% similar) in 240 aa overlap (1-240:1-240)

               10        20        30        40        50        60
pF1KE6 MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGTLH
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_003 MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA
              190       200       210       220       230       240

>>NP_000445 (OMIM: 105400,147450) superoxide dismutase [  (154 aa)
 initn: 351 init1: 205 opt: 355  Z-score: 411.8  bits: 82.9 E(85289): 3.4e-16
Smith-Waterman score: 355; 42.3% identity (66.9% similar) in 142 aa overlap (78-212:15-152)

        50        60        70        80        90       100       
pF1KE6 EVMQRRDDDGTLHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPN
                                     : :.. :.:    . . .. ...:. ::  
NP_000                 MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGL-TE--
                               10        20        30         40   

       110       120       130         140            150       160
pF1KE6 SSSRAIHVHQFGDLSQGCESTGPHYNPLAVPH--PQ----HPGDFGNF-AVRDGSLWRYR
        . ...:::.::: . :: :.:::.:::.  :  :.    : ::.::  : .::      
NP_000 -GLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSI
               50        60        70        80        90       100

              170       180       190       200       210       220
pF1KE6 AGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWER
          . ::.: : :.::..:::   ::::.:::. :...:::: :::: :.:.        
NP_000 EDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ      
              110       120       130       140       150          

              230       240
pF1KE6 QAREHSERKKRRRESECKAA

>>NP_005116 (OMIM: 603864) copper chaperone for superoxi  (274 aa)
 initn: 333 init1: 152 opt: 292  Z-score: 337.1  bits: 70.0 E(85289): 4.9e-12
Smith-Waterman score: 298; 35.8% identity (60.3% similar) in 179 aa overlap (78-235:99-267)

        50        60        70        80         90       100      
pF1KE6 EVMQRRDDDGTLHAACQVQPSATLDAAQPRVTGVVLFRQLAP-RAKLDAFFALEGFPTEP
                                     : ::: : ::.: :  ...  ...:.  ::
NP_005 TGRQAVLKGMGSGQLQNLGAAVAILGGPGTVQGVVRFLQLTPERCLIEG--TIDGL--EP
       70        80        90       100       110         120      

        110       120       130         140           150       160
pF1KE6 NSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPH--PQ----HPGDFGNFAVRDGSLWRYR
       .   ...::::.:::...:.: : :.:: .. :  ::    : ::.::  ::  .  :  
NP_005 GL--HGLHVHQYGDLTNNCNSCGNHFNPDGASHGGPQDSDRHRGDLGN--VRADADGRAI
            130       140       150       160       170         180

              170       180       190       200       210          
pF1KE6 AGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVG---------
         .        ...::....  :::::::::.  :  .::.:.:::: ...         
NP_005 FRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSAGLFQNP
              190       200       210       220       230       240

                  220       230       240  
pF1KE6 --VC---GPGLWERQAREHSERKKRRRESECKAA  
         .:   :  .::...:  .   : :.::       
NP_005 KQICSCDGLTIWEERGRPIA--GKGRKESAQPPAHL
              250       260         270    




240 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 11:20:50 2016 done: Tue Nov  8 11:20:51 2016
 Total Scan time:  6.280 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]