Result of FASTA (ccds) for
pFN21AE6214
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6214, 271 aa
1>>>pF1KE6214 271 - 271 aa - 271 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6992+/-0.000725; mu= 14.0434+/- 0.044
mean_var=82.3803+/-16.233, 0's: 0 Z-trim(111.1): 20 B-trim: 0 in 0/53
Lambda= 0.141307
statistics sampled from 12116 (12127) to 12116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.373), width: 16
Scan time: 1.990
The best scores are: opt bits E(32554)
CCDS12232.1 ICAM4 gene_id:3386|Hs108|chr19 ( 271) 1828 381.7 3e-106
CCDS42500.1 ICAM4 gene_id:3386|Hs108|chr19 ( 237) 1587 332.5 1.6e-91
CCDS32904.1 ICAM4 gene_id:3386|Hs108|chr19 ( 272) 912 195.0 4.9e-50
CCDS12233.1 ICAM5 gene_id:7087|Hs108|chr19 ( 924) 328 76.3 9e-14
CCDS11657.1 ICAM2 gene_id:3384|Hs108|chr17 ( 275) 289 68.0 8.4e-12
>>CCDS12232.1 ICAM4 gene_id:3386|Hs108|chr19 (271 aa)
initn: 1828 init1: 1828 opt: 1828 Z-score: 2021.1 bits: 381.7 E(32554): 3e-106
Smith-Waterman score: 1828; 100.0% identity (100.0% similar) in 271 aa overlap (1-271:1-271)
10 20 30 40 50 60
pF1KE6 MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 PGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TRWATSRITAYKPPHSVILEPPVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 TRWATSRITAYKPPHSVILEPPVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 ERFTGLDLANVTLTYEFAAGPRDFWQPVICHARLNLDGLVVRNSSAPITLMLAWSPAPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ERFTGLDLANVTLTYEFAAGPRDFWQPVICHARLNLDGLVVRNSSAPITLMLAWSPAPTA
190 200 210 220 230 240
250 260 270
pF1KE6 LASGSIAALVGILLTVGAAYLCKCLAMKSQA
:::::::::::::::::::::::::::::::
CCDS12 LASGSIAALVGILLTVGAAYLCKCLAMKSQA
250 260 270
>>CCDS42500.1 ICAM4 gene_id:3386|Hs108|chr19 (237 aa)
initn: 1587 init1: 1587 opt: 1587 Z-score: 1756.4 bits: 332.5 E(32554): 1.6e-91
Smith-Waterman score: 1587; 98.7% identity (99.6% similar) in 236 aa overlap (1-236:1-236)
10 20 30 40 50 60
pF1KE6 MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TRWATSRITAYKPPHSVILEPPVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TRWATSRITAYKPPHSVILEPPVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 ERFTGLDLANVTLTYEFAAGPRDFWQPVICHARLNLDGLVVRNSSAPITLMLAWSPAPTA
::::::::::::::::::::::::::::::::::::::::::::::::::::. .:
CCDS42 ERFTGLDLANVTLTYEFAAGPRDFWQPVICHARLNLDGLVVRNSSAPITLMLGEAPL
190 200 210 220 230
250 260 270
pF1KE6 LASGSIAALVGILLTVGAAYLCKCLAMKSQA
>>CCDS32904.1 ICAM4 gene_id:3386|Hs108|chr19 (272 aa)
initn: 910 init1: 910 opt: 912 Z-score: 1011.8 bits: 195.0 E(32554): 4.9e-50
Smith-Waterman score: 912; 93.7% identity (96.5% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MGSLFPLSLLFFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 PGKSVQLNCSNSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TRWATSRITAYKPPHSVILEPPVLKGRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESL
:::::::::::. : ... :
CCDS32 TRWATSRITAYSVPGGLLGGDPEAWKPGHLFRKPGALHRPGSGQRDLDLRVCCWTPRLLA
130 140 150 160 170 180
>>CCDS12233.1 ICAM5 gene_id:7087|Hs108|chr19 (924 aa)
initn: 273 init1: 250 opt: 328 Z-score: 360.7 bits: 76.3 E(32554): 9e-14
Smith-Waterman score: 328; 33.0% identity (57.7% similar) in 227 aa overlap (47-264:33-249)
20 30 40 50 60 70
pF1KE6 YPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQPGKSVQLNCSNSCPQP
:::. ..:. . :. : :. ::::..::.:
CCDS12 GPSPGLRRALLGLWAALGLGLFGLSAVSQEPFWADLQPRVAFVERGGSLWLNCSTNCPRP
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE6 QNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGKTRWATSRITAYKPPHS
. ..:.: ::.. : :: :.. ::.:.: . :. :: .: : . : ... :
CCDS12 ERGGLETSLRRNGTQRGLRWLARQLVDIREPETQPVCFFRCARRTLQARGLIRTFQRPDR
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE6 VILEP-PVLK--GRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESLERFTGLD--LANV
: : : : . :...:: :.: . : . :..:: .:.. . .: :.: ..
CCDS12 VELMPLPPWQPVGENFTLSCRVPGAGPRASLTLTLLRGAQELIRRS---FAGEPPRARGA
130 140 150 160 170
200 210 220 230 240
pF1KE6 TLTYEFAAGPRDFWQPVICHARLNL--DGL-VVRNSSAPITL-MLAWSPAPTALASGSIA
.:: : .: :.:.:.: :: . .::::: : .. :: ::.
CCDS12 VLTATVLARREDHGANFSCRAELDLRPHGLGLFENSSAPRELRTFSLSPDAPRLAAPR--
180 190 200 210 220 230
250 260 270
pF1KE6 ALVGILLTVGAAYLCKCLAMKSQA
:: ::. .:
CCDS12 -----LLEVGSERPVSCTLDGLFPASEARVYLALGDQNLSPDVTLEGDAFVATATATASA
240 250 260 270 280 290
>>CCDS11657.1 ICAM2 gene_id:3384|Hs108|chr17 (275 aa)
initn: 196 init1: 95 opt: 289 Z-score: 325.4 bits: 68.0 E(32554): 8.4e-12
Smith-Waterman score: 289; 27.0% identity (62.2% similar) in 230 aa overlap (41-262:20-245)
20 30 40 50 60 70
pF1KE6 FFLAAAYPGVGSALGRRTKRAQSPKGSPLAPSGTSVPFWVRMSPEFVAVQPGKSVQLNCS
:.. : :.. :. .::.: :...:::
CCDS11 MSSFGYRTLTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCS
10 20 30 40
80 90 100 110 120 130
pF1KE6 NSCPQPQNSSLRTPLRQGKTLRGPGWVSYQLLDVRAWSSLAHCLVTCAGKTRWATSRITA
..: ::. ..:.: : . . : : . .. . ... .: ::.:: . .: ...
CCDS11 TTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNI-SHDTVLQCHFTCSGKQESMNSNVSV
50 60 70 80 90 100
140 150 160 170 180
pF1KE6 YKPPHSVIL--EPPVLK-GRKYTLRCHVTQVFPVGYLVVTLRHGSRVIYSESLERFTGLD
:.::..::: .: .. :...:..:.: : :. :.. : .:..... :.. . .
CCDS11 YQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 LANVTLTYEFAAGPRDFWQPVICHARLNL---DGLVVRNSSAPITLMLAWSPAPTALASG
..: :.. .: .: . : : :.: : . .. ::: .. . :. .
CCDS11 -QEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAP-KMLEIYEPVSDSQMV-
170 180 190 200 210 220
250 260 270
pF1KE6 SIAALVGILLT--VGAAYLCKCLAMKSQA
:...:..::. : .. ::
CCDS11 IIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
230 240 250 260 270
271 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:09:02 2016 done: Tue Nov 8 11:09:03 2016
Total Scan time: 1.990 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]