Result of FASTA (omim) for
pFN21AE6213
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6213, 201 aa
1>>>pF1KE6213 201 - 201 aa - 201 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1010+/-0.000312; mu= 9.5586+/- 0.020
mean_var=81.0465+/-16.323, 0's: 0 Z-trim(116.9): 96 B-trim: 570 in 1/52
Lambda= 0.142465
statistics sampled from 28332 (28468) to 28332 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.334), width: 16
Scan time: 4.260
The best scores are: opt bits E(85289)
NP_037454 (OMIM: 614780,615085) sorting nexin-10 i ( 201) 1365 289.7 2.2e-78
XP_006715775 (OMIM: 614780,615085) PREDICTED: sort ( 201) 1365 289.7 2.2e-78
NP_001305128 (OMIM: 614780,615085) sorting nexin-1 ( 201) 1365 289.7 2.2e-78
NP_001186764 (OMIM: 614780,615085) sorting nexin-1 ( 201) 1365 289.7 2.2e-78
NP_001186766 (OMIM: 614780,615085) sorting nexin-1 ( 198) 1313 279.0 3.6e-75
XP_016867576 (OMIM: 614780,615085) PREDICTED: sort ( 227) 1310 278.4 6.2e-75
NP_001305127 (OMIM: 614780,615085) sorting nexin-1 ( 227) 1310 278.4 6.2e-75
XP_016867574 (OMIM: 614780,615085) PREDICTED: sort ( 227) 1310 278.4 6.2e-75
XP_016867575 (OMIM: 614780,615085) PREDICTED: sort ( 227) 1310 278.4 6.2e-75
XP_016867577 (OMIM: 614780,615085) PREDICTED: sort ( 161) 1072 229.4 2.4e-60
NP_001186767 (OMIM: 614780,615085) sorting nexin-1 ( 117) 769 167.1 1e-41
NP_689450 (OMIM: 614906) sorting nexin-11 isoform ( 270) 604 133.3 3.5e-31
NP_037455 (OMIM: 614906) sorting nexin-11 isoform ( 270) 604 133.3 3.5e-31
XP_011522999 (OMIM: 614906) PREDICTED: sorting nex ( 270) 604 133.3 3.5e-31
XP_005257317 (OMIM: 614906) PREDICTED: sorting nex ( 270) 604 133.3 3.5e-31
XP_005257319 (OMIM: 614906) PREDICTED: sorting nex ( 262) 588 130.0 3.3e-30
NP_001317249 (OMIM: 614906) sorting nexin-11 isofo ( 262) 588 130.0 3.3e-30
NP_001243114 (OMIM: 300883) sorting nexin-12 isofo ( 162) 227 55.7 4.7e-08
NP_037478 (OMIM: 300883) sorting nexin-12 isoform ( 162) 227 55.7 4.7e-08
NP_003786 (OMIM: 605930) sorting nexin-3 isoform a ( 162) 217 53.7 1.9e-07
NP_001243117 (OMIM: 300883) sorting nexin-12 isofo ( 158) 209 52.0 6e-07
NP_001287858 (OMIM: 605930) sorting nexin-3 isofor ( 140) 200 50.1 1.9e-06
XP_016856917 (OMIM: 614904) PREDICTED: sorting nex ( 336) 162 42.5 0.00093
XP_016856916 (OMIM: 614904) PREDICTED: sorting nex ( 387) 162 42.5 0.001
XP_016856915 (OMIM: 614904) PREDICTED: sorting nex ( 387) 162 42.5 0.001
XP_011539866 (OMIM: 614904) PREDICTED: sorting nex ( 387) 162 42.5 0.001
XP_006710741 (OMIM: 614904) PREDICTED: sorting nex ( 387) 162 42.5 0.001
XP_016856914 (OMIM: 614904) PREDICTED: sorting nex ( 387) 162 42.5 0.001
XP_006710740 (OMIM: 614904) PREDICTED: sorting nex ( 422) 162 42.5 0.0011
NP_057060 (OMIM: 614904) sorting nexin-7 isoform a ( 451) 162 42.6 0.0012
>>NP_037454 (OMIM: 614780,615085) sorting nexin-10 isofo (201 aa)
initn: 1365 init1: 1365 opt: 1365 Z-score: 1528.2 bits: 289.7 E(85289): 2.2e-78
Smith-Waterman score: 1365; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
130 140 150 160 170 180
190 200
pF1KE6 GHSSDDSSSHGCKVNTAPQES
:::::::::::::::::::::
NP_037 GHSSDDSSSHGCKVNTAPQES
190 200
>>XP_006715775 (OMIM: 614780,615085) PREDICTED: sorting (201 aa)
initn: 1365 init1: 1365 opt: 1365 Z-score: 1528.2 bits: 289.7 E(85289): 2.2e-78
Smith-Waterman score: 1365; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
130 140 150 160 170 180
190 200
pF1KE6 GHSSDDSSSHGCKVNTAPQES
:::::::::::::::::::::
XP_006 GHSSDDSSSHGCKVNTAPQES
190 200
>>NP_001305128 (OMIM: 614780,615085) sorting nexin-10 is (201 aa)
initn: 1365 init1: 1365 opt: 1365 Z-score: 1528.2 bits: 289.7 E(85289): 2.2e-78
Smith-Waterman score: 1365; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
130 140 150 160 170 180
190 200
pF1KE6 GHSSDDSSSHGCKVNTAPQES
:::::::::::::::::::::
NP_001 GHSSDDSSSHGCKVNTAPQES
190 200
>>NP_001186764 (OMIM: 614780,615085) sorting nexin-10 is (201 aa)
initn: 1365 init1: 1365 opt: 1365 Z-score: 1528.2 bits: 289.7 E(85289): 2.2e-78
Smith-Waterman score: 1365; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
130 140 150 160 170 180
190 200
pF1KE6 GHSSDDSSSHGCKVNTAPQES
:::::::::::::::::::::
NP_001 GHSSDDSSSHGCKVNTAPQES
190 200
>>NP_001186766 (OMIM: 614780,615085) sorting nexin-10 is (198 aa)
initn: 1310 init1: 1310 opt: 1313 Z-score: 1470.6 bits: 279.0 E(85289): 3.6e-75
Smith-Waterman score: 1313; 97.5% identity (98.0% similar) in 201 aa overlap (1-201:1-198)
10 20 30 40 50 60
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
:.: : ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMPLQ---EFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWL
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGL
120 130 140 150 160 170
190 200
pF1KE6 GHSSDDSSSHGCKVNTAPQES
:::::::::::::::::::::
NP_001 GHSSDDSSSHGCKVNTAPQES
180 190
>>XP_016867576 (OMIM: 614780,615085) PREDICTED: sorting (227 aa)
initn: 1310 init1: 1310 opt: 1310 Z-score: 1466.3 bits: 278.4 E(85289): 6.2e-75
Smith-Waterman score: 1310; 99.5% identity (100.0% similar) in 194 aa overlap (8-201:34-227)
10 20 30
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIH
.:::::::::::::::::::::::::::::
XP_016 MEGIGCMRHSSLTRQPKLPYRSLASARGGLQEFVSVWVRDPRIQKEDFWHSYIDYEICIH
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
130 140 150 160 170 180
160 170 180 190 200
pF1KE6 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
190 200 210 220
>>NP_001305127 (OMIM: 614780,615085) sorting nexin-10 is (227 aa)
initn: 1310 init1: 1310 opt: 1310 Z-score: 1466.3 bits: 278.4 E(85289): 6.2e-75
Smith-Waterman score: 1310; 99.5% identity (100.0% similar) in 194 aa overlap (8-201:34-227)
10 20 30
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIH
.:::::::::::::::::::::::::::::
NP_001 MEGIGCMRHSSLTRQPKLPYRSLASARGGLQEFVSVWVRDPRIQKEDFWHSYIDYEICIH
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
130 140 150 160 170 180
160 170 180 190 200
pF1KE6 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
190 200 210 220
>>XP_016867574 (OMIM: 614780,615085) PREDICTED: sorting (227 aa)
initn: 1310 init1: 1310 opt: 1310 Z-score: 1466.3 bits: 278.4 E(85289): 6.2e-75
Smith-Waterman score: 1310; 99.5% identity (100.0% similar) in 194 aa overlap (8-201:34-227)
10 20 30
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIH
.:::::::::::::::::::::::::::::
XP_016 MEGIGCMRHSSLTRQPKLPYRSLASARGGLQEFVSVWVRDPRIQKEDFWHSYIDYEICIH
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
130 140 150 160 170 180
160 170 180 190 200
pF1KE6 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
190 200 210 220
>>XP_016867575 (OMIM: 614780,615085) PREDICTED: sorting (227 aa)
initn: 1310 init1: 1310 opt: 1310 Z-score: 1466.3 bits: 278.4 E(85289): 6.2e-75
Smith-Waterman score: 1310; 99.5% identity (100.0% similar) in 194 aa overlap (8-201:34-227)
10 20 30
pF1KE6 MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIH
.:::::::::::::::::::::::::::::
XP_016 MEGIGCMRHSSLTRQPKLPYRSLASARGGLQEFVSVWVRDPRIQKEDFWHSYIDYEICIH
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFP
130 140 150 160 170 180
160 170 180 190 200
pF1KE6 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
190 200 210 220
>>XP_016867577 (OMIM: 614780,615085) PREDICTED: sorting (161 aa)
initn: 1072 init1: 1072 opt: 1072 Z-score: 1204.3 bits: 229.4 E(85289): 2.4e-60
Smith-Waterman score: 1072; 100.0% identity (100.0% similar) in 161 aa overlap (41-201:1-161)
20 30 40 50 60 70
pF1KE6 VSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNALL
::::::::::::::::::::::::::::::
XP_016 MCFTMKTSCVRRRYREFVWLRQRLQSNALL
10 20 30
80 90 100 110 120 130
pF1KE6 VQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSDSSLHLFLQSHLNSEDI
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE6 EACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGLGHSSDDSSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGLGHSSDDSSSH
100 110 120 130 140 150
200
pF1KE6 GCKVNTAPQES
:::::::::::
XP_016 GCKVNTAPQES
160
201 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 11:08:37 2016 done: Tue Nov 8 11:08:37 2016
Total Scan time: 4.260 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]