Result of FASTA (omim) for
pFN21AE6189
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6189, 171 aa
1>>>pF1KE6189 171 - 171 aa - 171 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8481+/-0.000351; mu= 14.6659+/- 0.022
mean_var=57.5304+/-11.518, 0's: 0 Z-trim(112.7): 29 B-trim: 0 in 0/53
Lambda= 0.169093
statistics sampled from 21676 (21690) to 21676 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.254), width: 16
Scan time: 5.330
The best scores are: opt bits E(85289)
XP_016874032 (OMIM: 186790,615617) PREDICTED: T-ce ( 171) 1133 284.4 6.2e-77
NP_000723 (OMIM: 186790,615617) T-cell surface gly ( 171) 1133 284.4 6.2e-77
NP_001035741 (OMIM: 186790,615617) T-cell surface ( 127) 594 152.8 1.8e-37
NP_000064 (OMIM: 186740,615607) T-cell surface gly ( 182) 428 112.4 3.8e-25
XP_006719004 (OMIM: 186740,615607) PREDICTED: T-ce ( 182) 428 112.4 3.8e-25
XP_005271781 (OMIM: 186740,615607) PREDICTED: T-ce ( 186) 273 74.6 9.4e-14
NP_937758 (OMIM: 221770,604142) TYRO protein tyros ( 112) 132 40.1 0.0014
NP_001166986 (OMIM: 221770,604142) TYRO protein ty ( 101) 130 39.6 0.0018
NP_003323 (OMIM: 221770,604142) TYRO protein tyros ( 113) 130 39.6 0.002
NP_001166985 (OMIM: 221770,604142) TYRO protein ty ( 102) 128 39.1 0.0026
>>XP_016874032 (OMIM: 186790,615617) PREDICTED: T-cell s (171 aa)
initn: 1133 init1: 1133 opt: 1133 Z-score: 1502.2 bits: 284.4 E(85289): 6.2e-77
Smith-Waterman score: 1133; 100.0% identity (100.0% similar) in 171 aa overlap (1-171:1-171)
10 20 30 40 50 60
pF1KE6 MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLAL
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 GVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
130 140 150 160 170
>>NP_000723 (OMIM: 186790,615617) T-cell surface glycopr (171 aa)
initn: 1133 init1: 1133 opt: 1133 Z-score: 1502.2 bits: 284.4 E(85289): 6.2e-77
Smith-Waterman score: 1133; 100.0% identity (100.0% similar) in 171 aa overlap (1-171:1-171)
10 20 30 40 50 60
pF1KE6 MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLAL
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 GVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
130 140 150 160 170
>>NP_001035741 (OMIM: 186790,615617) T-cell surface glyc (127 aa)
initn: 825 init1: 594 opt: 594 Z-score: 793.5 bits: 152.8 E(85289): 1.8e-37
Smith-Waterman score: 741; 73.7% identity (74.3% similar) in 171 aa overlap (1-171:1-127)
10 20 30 40 50 60
pF1KE6 MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEHSTFLSGLVLATLLSQVSPFKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLAL
:::::::::::::::::::::::::::::::
NP_001 GKRILDPRGIYRCNGTDIYKDKESTVQVHYR-----------------------------
70 80 90
130 140 150 160 170
pF1KE6 GVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
.:::::::::::::::::::::::::::::::::::
NP_001 ---------------TADTQALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
100 110 120
>>NP_000064 (OMIM: 186740,615607) T-cell surface glycopr (182 aa)
initn: 410 init1: 323 opt: 428 Z-score: 572.4 bits: 112.4 E(85289): 3.8e-25
Smith-Waterman score: 433; 39.3% identity (70.5% similar) in 183 aa overlap (1-169:1-180)
10 20 30 40
pF1KE6 MEHSTFLSGLVLATLLSQ---VSPFK----IPIEELED--RVFVNCNT---SITWV-EGT
::.. :. :.:: .: : .. .: . . . .. :...:.. .::: .:
NP_000 MEQGKGLAVLILAIILLQGTLAQSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 -VGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAG
.: : : . .::. ::::.:.:.:. ..: . .::.:::::.:.::. ::..:
NP_000 MIGFLTEDKKKWNLGSNAKDPRGMYQCKGS---QNKSKPLQVYYRMCQNCIELNAATISG
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 IIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGN
.. ..... ..::.::. .::.. : : :.: :.:: :::.::::.::.: ::::: ::
NP_000 FLFAEIVSIFVLAVGVYFIAGQDGVRQSRASDKQTLLPNDQLYQPLKDREDDQYSHLQGN
120 130 140 150 160 170
170
pF1KE6 WARNK
:
NP_000 QLRRN
180
>>XP_006719004 (OMIM: 186740,615607) PREDICTED: T-cell s (182 aa)
initn: 410 init1: 323 opt: 428 Z-score: 572.4 bits: 112.4 E(85289): 3.8e-25
Smith-Waterman score: 433; 39.3% identity (70.5% similar) in 183 aa overlap (1-169:1-180)
10 20 30 40
pF1KE6 MEHSTFLSGLVLATLLSQ---VSPFK----IPIEELED--RVFVNCNT---SITWV-EGT
::.. :. :.:: .: : .. .: . . . .. :...:.. .::: .:
XP_006 MEQGKGLAVLILAIILLQGTLAQSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 -VGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAG
.: : : . .::. ::::.:.:.:. ..: . .::.:::::.:.::. ::..:
XP_006 MIGFLTEDKKKWNLGSNAKDPRGMYQCKGS---QNKSKPLQVYYRMCQNCIELNAATISG
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 IIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGN
.. ..... ..::.::. .::.. : : :.: :.:: :::.::::.::.: ::::: ::
XP_006 FLFAEIVSIFVLAVGVYFIAGQDGVRQSRASDKQTLLPNDQLYQPLKDREDDQYSHLQGN
120 130 140 150 160 170
170
pF1KE6 WARNK
:
XP_006 QLRRN
180
>>XP_005271781 (OMIM: 186740,615607) PREDICTED: T-cell s (186 aa)
initn: 251 init1: 164 opt: 273 Z-score: 367.9 bits: 74.6 E(85289): 9.4e-14
Smith-Waterman score: 278; 32.4% identity (67.6% similar) in 148 aa overlap (1-134:1-145)
10 20 30 40
pF1KE6 MEHSTFLSGLVLATLLSQ---VSPFK----IPIEELED--RVFVNCNT---SITWVEG--
::.. :. :.:: .: : .. .: . . . .. :...:.. .::: .
XP_005 MEQGKGLAVLILAIILLQGTLAQSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 TVGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAG
.: : : . .::. ::::.:.:.:. ..: . .::.:::::.:.::. ::..:
XP_005 MIGFLTEDKKKWNLGSNAKDPRGMYQCKGS---QNKSKPLQVYYRMCQNCIELNAATISG
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 IIVTDVIATLLLALGVFCFAGHETGRLSGAADTQALLRNDQVYQPLRDRDDAQYSHLGGN
.. ..... ..::.::. .::.. : :
XP_005 FLFAEIVSIFVLAVGVYFIAGQDGVRQSRGKRMLLDERWDHLRPSAFLLPLCTQWKRLSW
120 130 140 150 160 170
>>NP_937758 (OMIM: 221770,604142) TYRO protein tyrosine (112 aa)
initn: 110 init1: 94 opt: 132 Z-score: 185.2 bits: 40.1 E(85289): 0.0014
Smith-Waterman score: 132; 33.3% identity (67.9% similar) in 81 aa overlap (86-163:25-104)
60 70 80 90 100 110
pF1KE6 TRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIAT
::.. . :: ..:...:::.. :.. :
NP_937 MGGLEPCSRLLLLPLLLAVSGLRPVQAQAQSDCSCSTVSPGVLAGIVMGDLVLT
10 20 30 40 50
120 130 140 150 160 170
pF1KE6 LLLALGVFCFAGHETGRLSGAADT---QALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
.:.::.:. : :. . : :::.. : . .... :: :. . . :: :
NP_937 VLIALAVY-FLGRLVPRGRGAAEATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK
60 70 80 90 100 110
>>NP_001166986 (OMIM: 221770,604142) TYRO protein tyrosi (101 aa)
initn: 119 init1: 91 opt: 130 Z-score: 183.2 bits: 39.6 E(85289): 0.0018
Smith-Waterman score: 130; 35.1% identity (68.9% similar) in 74 aa overlap (93-163:22-93)
70 80 90 100 110 120
pF1KE6 RILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLALGV
: :: ..:...:::.. :.. :.:.::.:
NP_001 MGGLEPCSRLLLLPLLLAVSDC-SCSTVSPGVLAGIVMGDLVLTVLIALAV
10 20 30 40 50
130 140 150 160 170
pF1KE6 FCFAGHETGRLSGAADT---QALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
. : :. . : :::.. : . .... :: :. . . :: :
NP_001 Y-FLGRLVPRGRGAAEATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK
60 70 80 90 100
>>NP_003323 (OMIM: 221770,604142) TYRO protein tyrosine (113 aa)
initn: 110 init1: 94 opt: 130 Z-score: 182.5 bits: 39.6 E(85289): 0.002
Smith-Waterman score: 130; 32.9% identity (67.1% similar) in 82 aa overlap (86-163:25-105)
60 70 80 90 100 110
pF1KE6 TRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIAT
::.. . :: ..:...:::.. :.. :
NP_003 MGGLEPCSRLLLLPLLLAVSGLRPVQAQAQSDCSCSTVSPGVLAGIVMGDLVLT
10 20 30 40 50
120 130 140 150 160 170
pF1KE6 LLLALGVFCFAGHETGRLSGAADT----QALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
.:.::.:. : :. . : :::.. : . .... :: :. . . :: :
NP_003 VLIALAVY-FLGRLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK
60 70 80 90 100 110
>>NP_001166985 (OMIM: 221770,604142) TYRO protein tyrosi (102 aa)
initn: 119 init1: 91 opt: 128 Z-score: 180.5 bits: 39.1 E(85289): 0.0026
Smith-Waterman score: 128; 34.7% identity (68.0% similar) in 75 aa overlap (93-163:22-94)
70 80 90 100 110 120
pF1KE6 RILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVAGIIVTDVIATLLLALGV
: :: ..:...:::.. :.. :.:.::.:
NP_001 MGGLEPCSRLLLLPLLLAVSDC-SCSTVSPGVLAGIVMGDLVLTVLIALAV
10 20 30 40 50
130 140 150 160 170
pF1KE6 FCFAGHETGRLSGAADT----QALLRNDQVYQPLRDRDDAQYSHLGGNWARNK
. : :. . : :::.. : . .... :: :. . . :: :
NP_001 Y-FLGRLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK
60 70 80 90 100
171 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:11:58 2016 done: Tue Nov 8 10:11:58 2016
Total Scan time: 5.330 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]