Result of FASTA (omim) for
pFN21AE6165
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6165, 147 aa
1>>>pF1KE6165 147 - 147 aa - 147 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3469+/-0.000331; mu= 10.8898+/- 0.021
mean_var=56.7604+/-11.148, 0's: 0 Z-trim(115.2): 17 B-trim: 167 in 1/52
Lambda= 0.170236
statistics sampled from 25418 (25435) to 25418 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.298), width: 16
Scan time: 4.220
The best scores are: opt bits E(85289)
NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 987 250.2 9.1e-67
NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 929 235.9 1.8e-62
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 754 192.9 1.5e-49
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 743 190.2 1e-48
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 732 187.5 6.5e-48
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 373 99.4 2.2e-21
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 373 99.4 2.2e-21
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 330 88.8 3.3e-18
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 330 88.8 3.3e-18
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 330 88.8 3.6e-18
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 321 86.6 1.5e-17
NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 282 77.0 1.2e-14
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 166 48.5 4.8e-06
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 166 48.5 4.8e-06
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 166 48.5 4.8e-06
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 166 48.5 4.8e-06
NP_067080 (OMIM: 605304) neuroglobin [Homo sapiens ( 151) 130 39.7 0.0021
>>NP_000510 (OMIM: 142000) hemoglobin subunit delta [Hom (147 aa)
initn: 987 init1: 987 opt: 987 Z-score: 1319.6 bits: 250.2 E(85289): 9.1e-67
Smith-Waterman score: 987; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::::::::::::::::::::::::
NP_000 KEFTPQMQAAYQKVVAGVANALAHKYH
130 140
>>NP_000509 (OMIM: 140700,141749,141900,603902,603903,60 (147 aa)
initn: 929 init1: 929 opt: 929 Z-score: 1242.6 bits: 235.9 E(85289): 1.8e-62
Smith-Waterman score: 929; 93.2% identity (98.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
:::::::::.::.::::::::: :::::::::::::::::::::::::::.:::::::::
NP_000 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::::::::::::::::::::. ::::::::::::::::::::::::::::..::
NP_000 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
::::: .::::::::::::::::::::
NP_000 KEFTPPVQAAYQKVVAGVANALAHKYH
130 140
>>NP_005321 (OMIM: 142100) hemoglobin subunit epsilon [H (147 aa)
initn: 754 init1: 754 opt: 754 Z-score: 1010.4 bits: 192.9 E(85289): 1.5e-49
Smith-Waterman score: 754; 72.8% identity (94.6% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
:::.: :::.::..::.:.::. .:::::::::::::::::::.:::.::::.:..::::
NP_005 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::: .:.:.. ..:::: .:..::::::::::::::::.:::::.: .:: .::
NP_005 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::..:::.::.:..:: :::::::
NP_005 KEFTPEVQAAWQKLVSAVAIALAHKYH
130 140
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 743 init1: 743 opt: 743 Z-score: 995.8 bits: 190.2 E(85289): 1e-48
Smith-Waterman score: 743; 72.1% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
: :.: :.:.....:::::::. .:::.:::::::::::::::.:::.::: .:.:::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::: ...:.. :::.:::::.:::::::::::::::::.::::::: ::: .::
NP_000 VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::..::..::.:.:::.::. .::
NP_000 KEFTPEVQASWQKMVTGVASALSSRYH
130 140
>>NP_000550 (OMIM: 141749,142200) hemoglobin subunit gam (147 aa)
initn: 732 init1: 732 opt: 732 Z-score: 981.2 bits: 187.5 E(85289): 6.5e-48
Smith-Waterman score: 732; 71.4% identity (93.2% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
: :.: :.:.....:::::::. .:::.:::::::::::::::.:::.::: .:.:::::
NP_000 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::: ...:. :::.:::::.:::::::::::::::::.::::::: ::: .::
NP_000 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::..::..::.:..::.::. .::
NP_000 KEFTPEVQASWQKMVTAVASALSSRYH
130 140
>>NP_000549 (OMIM: 140700,141800,604131,613978) hemoglob (142 aa)
initn: 305 init1: 263 opt: 373 Z-score: 504.9 bits: 99.4 E(85289): 2.2e-21
Smith-Waterman score: 373; 43.4% identity (74.5% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKVNVDA--VGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:.: .:: :.: ::::.. : :.::: :... .: :. .: : ::: :.
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
.::.::::: :.....::.:.. ...: ::.:: ::.::: ::.::.. :. .:: .
NP_000 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
. :::: ..:. .: .:.:...:. ::
NP_000 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>NP_000508 (OMIM: 140700,141850,604131,613978) hemoglob (142 aa)
initn: 305 init1: 263 opt: 373 Z-score: 504.9 bits: 99.4 E(85289): 2.2e-21
Smith-Waterman score: 373; 43.4% identity (74.5% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKVNVDA--VGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:.: .:: :.: ::::.. : :.::: :... .: :. .: : ::: :.
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
.::.::::: :.....::.:.. ...: ::.:: ::.::: ::.::.. :. .:: .
NP_000 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
. :::: ..:. .: .:.:...:. ::
NP_000 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa)
initn: 239 init1: 239 opt: 330 Z-score: 447.8 bits: 88.8 E(85289): 3.3e-18
Smith-Waterman score: 330; 38.6% identity (73.1% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKVNV--DAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:: :.: . ..:.:... :..: :.: ::.. .: :. .: : :: : :.
NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
...:::.::..: .:.. .:.. :..:.::::: :.::: ::.::.. :. .::
NP_005 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
: .:: . .::..: .. :...:..::
NP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa)
initn: 239 init1: 239 opt: 330 Z-score: 447.8 bits: 88.8 E(85289): 3.3e-18
Smith-Waterman score: 330; 38.6% identity (73.1% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKVNV--DAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:: :.: . ..:.:... :..: :.: ::.. .: :. .: : :: : :.
XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
...:::.::..: .:.. .:.. :..:.::::: :.::: ::.::.. :. .::
XP_005 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
: .:: . .::..: .. :...:..::
XP_005 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa)
initn: 239 init1: 239 opt: 330 Z-score: 447.2 bits: 88.8 E(85289): 3.6e-18
Smith-Waterman score: 330; 38.6% identity (73.1% similar) in 145 aa overlap (4-146:15-153)
10 20 30 40
pF1KE6 MVHLTPEEKTAVNALWGKVNV--DAVGGEALGRLLVVYPWTQRFFESFG
:: :.: . ..:.:... :..: :.: ::.. .: :. .: :
XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 DLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLL
:: : :. ...:::.::..: .:.. .:.. :..:.::::: :.::: ::.::
XP_005 DLH-P----GSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLL
60 70 80 90 100 110
110 120 130 140
pF1KE6 GNVLVCVLARNFGKEFTPQMQAAYQKVVAGVANALAHKYH
.. :. .:: : .:: . .::..: .. :...:..::
XP_005 SHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140 150
147 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:00:14 2016 done: Tue Nov 8 10:00:15 2016
Total Scan time: 4.220 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]