Result of FASTA (ccds) for
pFN21AE6165
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6165, 147 aa
1>>>pF1KE6165 147 - 147 aa - 147 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3497+/-0.000723; mu= 10.8342+/- 0.044
mean_var=57.3602+/-11.517, 0's: 0 Z-trim(108.3): 13 B-trim: 41 in 1/49
Lambda= 0.169344
statistics sampled from 10091 (10103) to 10091 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.31), width: 16
Scan time: 1.480
The best scores are: opt bits E(32554)
CCDS31376.1 HBD gene_id:3045|Hs108|chr11 ( 147) 987 248.9 8.4e-67
CCDS7753.1 HBB gene_id:3043|Hs108|chr11 ( 147) 929 234.7 1.6e-62
CCDS7756.1 HBE1 gene_id:3046|Hs108|chr11 ( 147) 754 192.0 1.2e-49
CCDS7755.1 HBG2 gene_id:3048|Hs108|chr11 ( 147) 743 189.3 7.4e-49
CCDS7754.1 HBG1 gene_id:3047|Hs108|chr11 ( 147) 732 186.6 4.8e-48
CCDS10398.1 HBA2 gene_id:3040|Hs108|chr16 ( 142) 373 98.9 1.2e-21
CCDS10399.1 HBA1 gene_id:3039|Hs108|chr16 ( 142) 373 98.9 1.2e-21
CCDS10397.1 HBZ gene_id:3050|Hs108|chr16 ( 142) 330 88.4 1.7e-18
CCDS10400.1 HBQ1 gene_id:3049|Hs108|chr16 ( 142) 321 86.2 7.8e-18
CCDS32347.1 HBM gene_id:3042|Hs108|chr16 ( 141) 282 76.6 5.7e-15
>>CCDS31376.1 HBD gene_id:3045|Hs108|chr11 (147 aa)
initn: 987 init1: 987 opt: 987 Z-score: 1312.8 bits: 248.9 E(32554): 8.4e-67
Smith-Waterman score: 987; 100.0% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::::::::::::::::::::::::
CCDS31 KEFTPQMQAAYQKVVAGVANALAHKYH
130 140
>>CCDS7753.1 HBB gene_id:3043|Hs108|chr11 (147 aa)
initn: 929 init1: 929 opt: 929 Z-score: 1236.2 bits: 234.7 E(32554): 1.6e-62
Smith-Waterman score: 929; 93.2% identity (98.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
:::::::::.::.::::::::: :::::::::::::::::::::::::::.:::::::::
CCDS77 MVHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::::::::::::::::::::. ::::::::::::::::::::::::::::..::
CCDS77 VKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
::::: .::::::::::::::::::::
CCDS77 KEFTPPVQAAYQKVVAGVANALAHKYH
130 140
>>CCDS7756.1 HBE1 gene_id:3046|Hs108|chr11 (147 aa)
initn: 754 init1: 754 opt: 754 Z-score: 1005.1 bits: 192.0 E(32554): 1.2e-49
Smith-Waterman score: 754; 72.8% identity (94.6% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
:::.: :::.::..::.:.::. .:::::::::::::::::::.:::.::::.:..::::
CCDS77 MVHFTAEEKAAVTSLWSKMNVEEAGGEALGRLLVVYPWTQRFFDSFGNLSSPSAILGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::: .:.:.. ..:::: .:..::::::::::::::::.:::::.: .:: .::
CCDS77 VKAHGKKVLTSFGDAIKNMDNLKPAFAKLSELHCDKLHVDPENFKLLGNVMVIILATHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::..:::.::.:..:: :::::::
CCDS77 KEFTPEVQAAWQKLVSAVAIALAHKYH
130 140
>>CCDS7755.1 HBG2 gene_id:3048|Hs108|chr11 (147 aa)
initn: 743 init1: 743 opt: 743 Z-score: 990.6 bits: 189.3 E(32554): 7.4e-49
Smith-Waterman score: 743; 72.1% identity (93.9% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
: :.: :.:.....:::::::. .:::.:::::::::::::::.:::.::: .:.:::::
CCDS77 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::: ...:.. :::.:::::.:::::::::::::::::.::::::: ::: .::
CCDS77 VKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::..::..::.:.:::.::. .::
CCDS77 KEFTPEVQASWQKMVTGVASALSSRYH
130 140
>>CCDS7754.1 HBG1 gene_id:3047|Hs108|chr11 (147 aa)
initn: 732 init1: 732 opt: 732 Z-score: 976.1 bits: 186.6 E(32554): 4.8e-48
Smith-Waterman score: 732; 71.4% identity (93.2% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KE6 MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPK
: :.: :.:.....:::::::. .:::.:::::::::::::::.:::.::: .:.:::::
CCDS77 MGHFTEEDKATITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGNPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFG
::::::::: ...:. :::.:::::.:::::::::::::::::.::::::: ::: .::
CCDS77 VKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIHFG
70 80 90 100 110 120
130 140
pF1KE6 KEFTPQMQAAYQKVVAGVANALAHKYH
:::::..::..::.:..::.::. .::
CCDS77 KEFTPEVQASWQKMVTAVASALSSRYH
130 140
>>CCDS10398.1 HBA2 gene_id:3040|Hs108|chr16 (142 aa)
initn: 305 init1: 263 opt: 373 Z-score: 502.3 bits: 98.9 E(32554): 1.2e-21
Smith-Waterman score: 373; 43.4% identity (74.5% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKVNVDA--VGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:.: .:: :.: ::::.. : :.::: :... .: :. .: : ::: :.
CCDS10 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
.::.::::: :.....::.:.. ...: ::.:: ::.::: ::.::.. :. .:: .
CCDS10 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
. :::: ..:. .: .:.:...:. ::
CCDS10 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>CCDS10399.1 HBA1 gene_id:3039|Hs108|chr16 (142 aa)
initn: 305 init1: 263 opt: 373 Z-score: 502.3 bits: 98.9 E(32554): 1.2e-21
Smith-Waterman score: 373; 43.4% identity (74.5% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKVNVDA--VGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:.: .:: :.: ::::.. : :.::: :... .: :. .: : ::: :.
CCDS10 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHF-DLSH-----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
.::.::::: :.....::.:.. ...: ::.:: ::.::: ::.::.. :. .:: .
CCDS10 AQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
. :::: ..:. .: .:.:...:. ::
CCDS10 LPAEFTPAVHASLDKFLASVSTVLTSKYR
120 130 140
>>CCDS10397.1 HBZ gene_id:3050|Hs108|chr16 (142 aa)
initn: 239 init1: 239 opt: 330 Z-score: 445.5 bits: 88.4 E(32554): 1.7e-18
Smith-Waterman score: 330; 38.6% identity (73.1% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKVNV--DAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:: :.: . ..:.:... :..: :.: ::.. .: :. .: : :: : :.
CCDS10 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLH-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
...:::.::..: .:.. .:.. :..:.::::: :.::: ::.::.. :. .::
CCDS10 AQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAAR
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
: .:: . .::..: .. :...:..::
CCDS10 FPADFTAEAHAAWDKFLSVVSSVLTEKYR
120 130 140
>>CCDS10400.1 HBQ1 gene_id:3049|Hs108|chr16 (142 aa)
initn: 319 init1: 226 opt: 321 Z-score: 433.6 bits: 86.2 E(32554): 7.8e-18
Smith-Waterman score: 321; 40.7% identity (70.3% similar) in 145 aa overlap (4-146:3-141)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKV--NVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:. :... : ::: :. :: . ::: : ....: :. .: : ::: : :.
CCDS10 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYF-SHLDLS-P----GS
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
.:.:::.:: :.: .. .::.: ..: ::.:: .:.::: .:.:::. :. .:::.
CCDS10 SQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
. .:.: .::. .: .. : .::. .:
CCDS10 YPGDFSPALQASLDKFLSHVISALVSEYR
120 130 140
>>CCDS32347.1 HBM gene_id:3042|Hs108|chr16 (141 aa)
initn: 263 init1: 229 opt: 282 Z-score: 382.2 bits: 76.6 E(32554): 5.7e-15
Smith-Waterman score: 282; 36.6% identity (68.3% similar) in 145 aa overlap (4-146:2-140)
10 20 30 40 50
pF1KE6 MVHLTPEEKTAVNALWGKV--NVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
:. .:.. . .: . . :.: : ::..::: :. .: .. . ::.
CCDS32 MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLS--ACQDAT---
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
.. .::...:.: . .. :.:::....: :..:: :.::: :: :: . . ::: .
CCDS32 -QLLSHGQRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASH
60 70 80 90 100 110
120 130 140
pF1KE6 FGKEFTPQMQAAYQKVVAGVANALAHKYH
. ::: :::::..: ..::: .:..::
CCDS32 LQDEFTVQMQAAWDKFLTGVAVVLTEKYR
120 130 140
147 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:00:13 2016 done: Tue Nov 8 10:00:14 2016
Total Scan time: 1.480 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]