Result of FASTA (omim) for
pFN21AE6107
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6107, 157 aa
1>>>pF1KE6107 157 - 157 aa - 157 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7430+/-0.000342; mu= 14.8380+/- 0.021
mean_var=54.8694+/-11.146, 0's: 0 Z-trim(113.3): 62 B-trim: 94 in 2/51
Lambda= 0.173145
statistics sampled from 22464 (22542) to 22464 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.264), width: 16
Scan time: 3.430
The best scores are: opt bits E(85289)
NP_003907 (OMIM: 300629) AP-1 complex subunit sigm ( 157) 1021 262.7 1.8e-70
NP_001259000 (OMIM: 300629) AP-1 complex subunit s ( 160) 1005 258.7 2.9e-69
XP_011543901 (OMIM: 300629) PREDICTED: AP-1 comple ( 202) 944 243.5 1.3e-64
XP_016885414 (OMIM: 300629) PREDICTED: AP-1 comple ( 202) 944 243.5 1.3e-64
XP_016885415 (OMIM: 300629) PREDICTED: AP-1 comple ( 189) 932 240.5 1e-63
XP_005274671 (OMIM: 300629) PREDICTED: AP-1 comple ( 195) 932 240.5 1e-63
NP_001274 (OMIM: 603531,609313) AP-1 complex subun ( 158) 927 239.2 2.1e-63
NP_001034658 (OMIM: 615781,616106) AP-1 complex su ( 154) 766 199.0 2.6e-51
XP_011508902 (OMIM: 615781,616106) PREDICTED: AP-1 ( 108) 516 136.4 1.2e-32
NP_004060 (OMIM: 600740,602242) AP-2 complex subun ( 142) 460 122.5 2.5e-28
NP_001288010 (OMIM: 600740,602242) AP-2 complex su ( 144) 460 122.5 2.5e-28
NP_001288005 (OMIM: 600740,602242) AP-2 complex su ( 158) 460 122.6 2.7e-28
NP_001241658 (OMIM: 607243,614067) AP-4 complex su ( 144) 389 104.8 5.5e-23
NP_001121598 (OMIM: 607243,614067) AP-4 complex su ( 144) 389 104.8 5.5e-23
NP_001241657 (OMIM: 607243,614067) AP-4 complex su ( 144) 389 104.8 5.5e-23
NP_005820 (OMIM: 602416) AP-3 complex subunit sigm ( 193) 349 94.9 7.1e-20
NP_001305022 (OMIM: 601507) AP-3 complex subunit s ( 162) 346 94.1 1e-19
XP_011541438 (OMIM: 601507) PREDICTED: AP-3 comple ( 262) 346 94.2 1.5e-19
XP_016864513 (OMIM: 601507) PREDICTED: AP-3 comple ( 262) 346 94.2 1.5e-19
NP_001275 (OMIM: 601507) AP-3 complex subunit sigm ( 193) 344 93.6 1.7e-19
NP_001288007 (OMIM: 600740,602242) AP-2 complex su ( 156) 335 91.3 6.7e-19
XP_011524726 (OMIM: 600740,602242) PREDICTED: AP-2 ( 158) 335 91.3 6.8e-19
XP_011524725 (OMIM: 600740,602242) PREDICTED: AP-2 ( 172) 335 91.3 7.3e-19
NP_001241656 (OMIM: 607243,614067) AP-4 complex su ( 149) 301 82.8 2.3e-16
XP_005267350 (OMIM: 607243,614067) PREDICTED: AP-4 ( 159) 301 82.8 2.5e-16
XP_011534674 (OMIM: 607243,614067) PREDICTED: AP-4 ( 159) 301 82.8 2.5e-16
NP_009008 (OMIM: 607243,614067) AP-4 complex subun ( 159) 301 82.8 2.5e-16
XP_011534673 (OMIM: 607243,614067) PREDICTED: AP-4 ( 159) 301 82.8 2.5e-16
NP_001305023 (OMIM: 601507) AP-3 complex subunit s ( 157) 289 79.8 1.9e-15
NP_001002924 (OMIM: 601507) AP-3 complex subunit s ( 171) 285 78.9 4.2e-15
NP_001241655 (OMIM: 607243,614067) AP-4 complex su ( 135) 280 77.5 8.2e-15
NP_067586 (OMIM: 600740,602242) AP-2 complex subun ( 104) 193 55.7 2.3e-08
NP_001305020 (OMIM: 601507) AP-3 complex subunit s ( 169) 194 56.1 2.9e-08
XP_016864514 (OMIM: 601507) PREDICTED: AP-3 comple ( 238) 194 56.2 3.8e-08
NP_001305019 (OMIM: 601507) AP-3 complex subunit s ( 125) 156 46.6 1.6e-05
NP_001258664 (OMIM: 615472) coatomer subunit zeta- ( 160) 126 39.1 0.0036
NP_057513 (OMIM: 615526) coatomer subunit zeta-2 [ ( 210) 125 38.9 0.0053
NP_057141 (OMIM: 615472) coatomer subunit zeta-1 i ( 177) 121 37.9 0.0092
XP_016874486 (OMIM: 615472) PREDICTED: coatomer su ( 180) 121 37.9 0.0094
NP_001258665 (OMIM: 615472) coatomer subunit zeta- ( 185) 121 37.9 0.0096
>>NP_003907 (OMIM: 300629) AP-1 complex subunit sigma-2 (157 aa)
initn: 1021 init1: 1021 opt: 1021 Z-score: 1386.3 bits: 262.7 E(85289): 1.8e-70
Smith-Waterman score: 1021; 100.0% identity (100.0% similar) in 157 aa overlap (1-157:1-157)
10 20 30 40 50 60
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGG
70 80 90 100 110 120
130 140 150
pF1KE6 EVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
:::::::::::::::::::::::::::::::::::::
NP_003 EVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
130 140 150
>>NP_001259000 (OMIM: 300629) AP-1 complex subunit sigma (160 aa)
initn: 954 init1: 940 opt: 1005 Z-score: 1364.6 bits: 258.7 E(85289): 2.9e-69
Smith-Waterman score: 1005; 98.1% identity (98.1% similar) in 160 aa overlap (1-157:1-160)
10 20 30 40 50 60
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGG
70 80 90 100 110 120
130 140 150
pF1KE6 EVQETSKKNVLKAIEQADLLQE---EAETPRSVLEEIGLT
:::::::::::::::::::::: :::::::::::::::
NP_001 EVQETSKKNVLKAIEQADLLQEDAKEAETPRSVLEEIGLT
130 140 150 160
>>XP_011543901 (OMIM: 300629) PREDICTED: AP-1 complex su (202 aa)
initn: 944 init1: 944 opt: 944 Z-score: 1280.8 bits: 243.5 E(85289): 1.3e-64
Smith-Waterman score: 944; 98.6% identity (100.0% similar) in 146 aa overlap (1-146:43-188)
10 20 30
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
::::::::::::::::::::::::::::::
XP_011 SLPQHGDRGFPFAAAAAAGQAPPRPRPAAAMQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::..::
XP_011 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEKTETMYHS
140 150 160 170 180 190
pF1KE6 LEEIGLT
XP_011 KSFIGFKKAY
200
>>XP_016885414 (OMIM: 300629) PREDICTED: AP-1 complex su (202 aa)
initn: 944 init1: 944 opt: 944 Z-score: 1280.8 bits: 243.5 E(85289): 1.3e-64
Smith-Waterman score: 944; 98.6% identity (100.0% similar) in 146 aa overlap (1-146:43-188)
10 20 30
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
::::::::::::::::::::::::::::::
XP_016 SLPQHGDRGFPFAAAAAAGQAPPRPRPAAAMQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::..::
XP_016 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEKTETMYHS
140 150 160 170 180 190
pF1KE6 LEEIGLT
XP_016 KSFIGFKKAY
200
>>XP_016885415 (OMIM: 300629) PREDICTED: AP-1 complex su (189 aa)
initn: 932 init1: 932 opt: 932 Z-score: 1265.0 bits: 240.5 E(85289): 1e-63
Smith-Waterman score: 932; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:43-184)
10 20 30
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
::::::::::::::::::::::::::::::
XP_016 SLPQHGDRGFPFAAAAAAGQAPPRPRPAAAMQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQESFFSS
140 150 160 170 180
pF1KE6 LEEIGLT
>>XP_005274671 (OMIM: 300629) PREDICTED: AP-1 complex su (195 aa)
initn: 932 init1: 932 opt: 932 Z-score: 1264.8 bits: 240.5 E(85289): 1e-63
Smith-Waterman score: 932; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:43-184)
10 20 30
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
::::::::::::::::::::::::::::::
XP_005 SLPQHGDRGFPFAAAAAAGQAPPRPRPAAAMQFMLLFSRQGKLRLQKWYVPLSDKEKKKI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELL
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEPRHEYFNV
140 150 160 170 180 190
pF1KE6 LEEIGLT
XP_005 PVY
>>NP_001274 (OMIM: 603531,609313) AP-1 complex subunit s (158 aa)
initn: 927 init1: 927 opt: 927 Z-score: 1259.4 bits: 239.2 E(85289): 2.1e-63
Smith-Waterman score: 927; 87.8% identity (97.4% similar) in 156 aa overlap (1-156:2-157)
10 20 30 40 50
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYK
:.:::::::::::::::::. ::::.::..:::.:.::::::::::::::::::.:::
NP_001 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 RYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG
:::::::::::: :::::::::.:::::::::::::::::::::::::::::::::::.:
NP_001 RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG
70 80 90 100 110 120
120 130 140 150
pF1KE6 GEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
:.::.::::.:::::::::::::: :.:::::::.::
NP_001 GDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
130 140 150
>>NP_001034658 (OMIM: 615781,616106) AP-1 complex subuni (154 aa)
initn: 785 init1: 753 opt: 766 Z-score: 1042.2 bits: 199.0 E(85289): 2.6e-51
Smith-Waterman score: 766; 75.2% identity (93.1% similar) in 145 aa overlap (1-145:2-146)
10 20 30 40 50
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYK
..:.:::::::::::::::. : :::.::::::.:: .:.: . ::..:..::.:::
NP_001 MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 RYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG
::::::::::::.:::::.::::.::::::::::::.::::::::::::::::::::..:
NP_001 RYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG
70 80 90 100 110 120
120 130 140 150
pF1KE6 GEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
::.:::::: ..::::..:.::: :
NP_001 GEIQETSKKIAVKAIEDSDMLQETMEEYMNKPTF
130 140 150
>>XP_011508902 (OMIM: 615781,616106) PREDICTED: AP-1 com (108 aa)
initn: 517 init1: 503 opt: 516 Z-score: 707.0 bits: 136.4 E(85289): 1.2e-32
Smith-Waterman score: 516; 72.7% identity (91.9% similar) in 99 aa overlap (1-99:2-100)
10 20 30 40 50
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYK
..:.:::::::::::::::. : :::.::::::.:: .:.: . ::..:..::.:::
XP_011 MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 RYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG
::::::::::::.:::::.::::.::::::::::::.. :
XP_011 RYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNTMEEYMNKPTF
70 80 90 100
120 130 140 150
pF1KE6 GEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
>>NP_004060 (OMIM: 600740,602242) AP-2 complex subunit s (142 aa)
initn: 437 init1: 437 opt: 460 Z-score: 629.6 bits: 122.5 E(85289): 2.5e-28
Smith-Waterman score: 460; 47.8% identity (80.6% similar) in 134 aa overlap (1-134:2-135)
10 20 30 40 50
pF1KE6 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYK
..:.:. .: :: :: :::. ..: ::.:. .:. .: .: : .:.:.:..::.:.
NP_004 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 RYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLG
:::.:::: .. .::.: :: :: .::.:..:: .:::::..::: :.: ..::..:.
NP_004 RYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA
70 80 90 100 110 120
120 130 140 150
pF1KE6 GEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
::..:::. .::: .
NP_004 GEIRETSQTKVLKQLLMLQSLE
130 140
157 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 09:30:29 2016 done: Tue Nov 8 09:30:30 2016
Total Scan time: 3.430 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]