Result of FASTA (omim) for
pFN21AE5810
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5810, 1455 aa
1>>>pF1KE5810 1455 - 1455 aa - 1455 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5740+/-0.000403; mu= 22.1273+/- 0.025
mean_var=74.7712+/-15.033, 0's: 0 Z-trim(112.5): 20 B-trim: 22 in 1/51
Lambda= 0.148323
statistics sampled from 21486 (21501) to 21486 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.252), width: 16
Scan time: 12.710
The best scores are: opt bits E(85289)
NP_000126 (OMIM: 189960,227650,607139) Fanconi ane (1455) 9683 2082.4 0
NP_001273096 (OMIM: 189960,227650,607139) Fanconi (1424) 9252 1990.2 0
XP_005256351 (OMIM: 189960,227650,607139) PREDICTE (1463) 9252 1990.2 0
XP_011521249 (OMIM: 189960,227650,607139) PREDICTE (1122) 7004 1509.1 0
XP_011521248 (OMIM: 189960,227650,607139) PREDICTE (1122) 7004 1509.1 0
XP_016878534 (OMIM: 189960,227650,607139) PREDICTE ( 985) 6289 1356.1 0
XP_016878533 (OMIM: 189960,227650,607139) PREDICTE (1412) 6289 1356.2 0
XP_011521247 (OMIM: 189960,227650,607139) PREDICTE (1420) 6289 1356.2 0
XP_011521250 (OMIM: 189960,227650,607139) PREDICTE ( 746) 4850 1048.1 0
XP_016878535 (OMIM: 189960,227650,607139) PREDICTE ( 438) 2688 585.3 3.5e-166
NP_001018122 (OMIM: 189960,227650,607139) Fanconi ( 297) 1958 429.0 2.7e-119
>>NP_000126 (OMIM: 189960,227650,607139) Fanconi anemia (1455 aa)
initn: 9683 init1: 9683 opt: 9683 Z-score: 11186.3 bits: 2082.4 E(85289): 0
Smith-Waterman score: 9683; 100.0% identity (100.0% similar) in 1455 aa overlap (1-1455:1-1455)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE5 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE5 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE5 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE5 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE5 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE5 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE5 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE5 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE5 GRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQ
1390 1400 1410 1420 1430 1440
1450
pF1KE5 QAAPDADLSQEPHLF
:::::::::::::::
NP_000 QAAPDADLSQEPHLF
1450
>>NP_001273096 (OMIM: 189960,227650,607139) Fanconi anem (1424 aa)
initn: 9240 init1: 9240 opt: 9252 Z-score: 10688.0 bits: 1990.2 E(85289): 0
Smith-Waterman score: 9252; 98.7% identity (99.0% similar) in 1414 aa overlap (1-1413:1-1414)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE5 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE5 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE5 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE5 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE5 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE5 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE5 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE5 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE5 GRSLELKGQ-GNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSR
::::::::: :.: .:. : . :.:
NP_001 GRSLELKGQAGQPRGTDNKSSSFSAAVNTSVPEKELLTRGRAAG
1390 1400 1410 1420
1440 1450
pF1KE5 QQAAPDADLSQEPHLF
>>XP_005256351 (OMIM: 189960,227650,607139) PREDICTED: F (1463 aa)
initn: 9240 init1: 9240 opt: 9252 Z-score: 10687.8 bits: 1990.2 E(85289): 0
Smith-Waterman score: 9252; 98.7% identity (99.0% similar) in 1414 aa overlap (1-1413:1-1414)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE5 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE5 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE5 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE5 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE5 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE5 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE5 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE5 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE5 GRSLELKGQ-GNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSR
::::::::: :.: .:. : . :.:
XP_005 GRSLELKGQAGQPRGTDNKSSSFSAAVNTSVPEKELLTRGRGNVKMPTLGHVGDMRIDSC
1390 1400 1410 1420 1430 1440
1440 1450
pF1KE5 QQAAPDADLSQEPHLF
XP_005 LGHVPAWLAIQLDYFCQSPSPVV
1450 1460
>>XP_011521249 (OMIM: 189960,227650,607139) PREDICTED: F (1122 aa)
initn: 6992 init1: 6992 opt: 7004 Z-score: 8089.8 bits: 1509.1 E(85289): 0
Smith-Waterman score: 7004; 98.2% identity (98.7% similar) in 1073 aa overlap (342-1413:1-1073)
320 330 340 350 360 370
pF1KE5 STDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYRRLFVMLSAEEL
::::::::::::::::::::::::::::::
XP_011 MQREWSFARTHPLLTSLYRRLFVMLSAEEL
10 20 30
380 390 400 410 420 430
pF1KE5 VGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFESCQLDSMVTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFESCQLDSMVTAF
40 50 60 70 80 90
440 450 460 470 480 490
pF1KE5 LVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQV
100 110 120 130 140 150
500 510 520 530 540 550
pF1KE5 HILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDITEPHSQALQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDITEPHSQALQDV
160 170 180 190 200 210
560 570 580 590 600 610
pF1KE5 EKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRAD
220 230 240 250 260 270
620 630 640 650 660 670
pF1KE5 KIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRD
280 290 300 310 320 330
680 690 700 710 720 730
pF1KE5 VISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVDLLLTSFCQNLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVDLLLTSFCQNLM
340 350 360 370 380 390
740 750 760 770 780 790
pF1KE5 AASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHL
400 410 420 430 440 450
800 810 820 830 840 850
pF1KE5 GESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQ
460 470 480 490 500 510
860 870 880 890 900 910
pF1KE5 SRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPSADWQRAALSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPSADWQRAALSLW
520 530 540 550 560 570
920 930 940 950 960 970
pF1KE5 THRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASG
580 590 600 610 620 630
980 990 1000 1010 1020 1030
pF1KE5 GCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQ
640 650 660 670 680 690
1040 1050 1060 1070 1080 1090
pF1KE5 QDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLC
700 710 720 730 740 750
1100 1110 1120 1130 1140 1150
pF1KE5 GSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLM
760 770 780 790 800 810
1160 1170 1180 1190 1200 1210
pF1KE5 VDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFL
820 830 840 850 860 870
1220 1230 1240 1250 1260 1270
pF1KE5 SPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFLFFFSLMGLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFLFFFSLMGLLSS
880 890 900 910 920 930
1280 1290 1300 1310 1320 1330
pF1KE5 HLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLL
940 950 960 970 980 990
1340 1350 1360 1370 1380 1390
pF1KE5 PFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQ-G
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 PFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQAG
1000 1010 1020 1030 1040 1050
1400 1410 1420 1430 1440 1450
pF1KE5 NPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQQAAPDADLSQ
.: .:. : . :.:
XP_011 QPRGTDNKSSSFSAAVNTSVPEKELLTRGRGNVKMPTLGHVGDMRIDSCLGHVPAWLAIQ
1060 1070 1080 1090 1100 1110
>>XP_011521248 (OMIM: 189960,227650,607139) PREDICTED: F (1122 aa)
initn: 6992 init1: 6992 opt: 7004 Z-score: 8089.8 bits: 1509.1 E(85289): 0
Smith-Waterman score: 7004; 98.2% identity (98.7% similar) in 1073 aa overlap (342-1413:1-1073)
320 330 340 350 360 370
pF1KE5 STDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYRRLFVMLSAEEL
::::::::::::::::::::::::::::::
XP_011 MQREWSFARTHPLLTSLYRRLFVMLSAEEL
10 20 30
380 390 400 410 420 430
pF1KE5 VGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFESCQLDSMVTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFESCQLDSMVTAF
40 50 60 70 80 90
440 450 460 470 480 490
pF1KE5 LVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQV
100 110 120 130 140 150
500 510 520 530 540 550
pF1KE5 HILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDITEPHSQALQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDITEPHSQALQDV
160 170 180 190 200 210
560 570 580 590 600 610
pF1KE5 EKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRAD
220 230 240 250 260 270
620 630 640 650 660 670
pF1KE5 KIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRD
280 290 300 310 320 330
680 690 700 710 720 730
pF1KE5 VISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVDLLLTSFCQNLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVDLLLTSFCQNLM
340 350 360 370 380 390
740 750 760 770 780 790
pF1KE5 AASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHL
400 410 420 430 440 450
800 810 820 830 840 850
pF1KE5 GESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQ
460 470 480 490 500 510
860 870 880 890 900 910
pF1KE5 SRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPSADWQRAALSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPSADWQRAALSLW
520 530 540 550 560 570
920 930 940 950 960 970
pF1KE5 THRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASG
580 590 600 610 620 630
980 990 1000 1010 1020 1030
pF1KE5 GCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQ
640 650 660 670 680 690
1040 1050 1060 1070 1080 1090
pF1KE5 QDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKRILLRLPSSVLC
700 710 720 730 740 750
1100 1110 1120 1130 1140 1150
pF1KE5 GSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLM
760 770 780 790 800 810
1160 1170 1180 1190 1200 1210
pF1KE5 VDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFL
820 830 840 850 860 870
1220 1230 1240 1250 1260 1270
pF1KE5 SPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFLFFFSLMGLLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFLFFFSLMGLLSS
880 890 900 910 920 930
1280 1290 1300 1310 1320 1330
pF1KE5 HLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLL
940 950 960 970 980 990
1340 1350 1360 1370 1380 1390
pF1KE5 PFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQ-G
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 PFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQAG
1000 1010 1020 1030 1040 1050
1400 1410 1420 1430 1440 1450
pF1KE5 NPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQQAAPDADLSQ
.: .:. : . :.:
XP_011 QPRGTDNKSSSFSAAVNTSVPEKELLTRGRGNVKMPTLGHVGDMRIDSCLGHVPAWLAIQ
1060 1070 1080 1090 1100 1110
>>XP_016878534 (OMIM: 189960,227650,607139) PREDICTED: F (985 aa)
initn: 6289 init1: 6289 opt: 6289 Z-score: 7263.7 bits: 1356.1 E(85289): 0
Smith-Waterman score: 6289; 100.0% identity (100.0% similar) in 951 aa overlap (1-951:1-951)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE5 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERVSLCWPGWS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE5 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
XP_016 TVMHSRLTAASLSRARVILLPQPPE
970 980
>>XP_016878533 (OMIM: 189960,227650,607139) PREDICTED: F (1412 aa)
initn: 6289 init1: 6289 opt: 6289 Z-score: 7261.4 bits: 1356.2 E(85289): 0
Smith-Waterman score: 9277; 97.0% identity (97.0% similar) in 1455 aa overlap (1-1455:1-1412)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE5 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTER---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE5 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
::::::::::::::::::::::::::
XP_016 ----------------------------------SRSYDHSENSDLVFGGRTGNEDIISR
960 970
1030 1040 1050 1060 1070 1080
pF1KE5 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KE5 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KE5 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KE5 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KE5 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE5 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE5 GRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSRQ
1340 1350 1360 1370 1380 1390
1450
pF1KE5 QAAPDADLSQEPHLF
:::::::::::::::
XP_016 QAAPDADLSQEPHLF
1400 1410
>>XP_011521247 (OMIM: 189960,227650,607139) PREDICTED: F (1420 aa)
initn: 6289 init1: 6289 opt: 6289 Z-score: 7261.4 bits: 1356.2 E(85289): 0
Smith-Waterman score: 8846; 95.6% identity (96.0% similar) in 1414 aa overlap (1-1413:1-1371)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE5 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLGLAALAVHLGESRSALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE5 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSEEDVASLSWRPLHLPS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE5 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIH
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTER---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE5 EHFLPESSASGGCDGDLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISR
::::::::::::::::::::::::::
XP_011 ----------------------------------SRSYDHSENSDLVFGGRTGNEDIISR
960 970
1030 1040 1050 1060 1070 1080
pF1KE5 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSVAASLQRQRELLMYKR
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KE5 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLN
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KE5 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACLRSRDPSLMVDFILAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKL
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KE5 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQLKKLDCEREELLVFL
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KE5 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLL
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE5 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVAPDQHTRLLPFAFYSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPA
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430
pF1KE5 GRSLELKGQ-GNPVELITKARLFLLQLIPRCPKKSFSHVAELLADRGDCDPEVSAALQSR
::::::::: :.: .:. : . :.:
XP_011 GRSLELKGQAGQPRGTDNKSSSFSAAVNTSVPEKELLTRGRGNVKMPTLGHVGDMRIDSC
1340 1350 1360 1370 1380 1390
1440 1450
pF1KE5 QQAAPDADLSQEPHLF
XP_011 LGHVPAWLAIQLDYFCQSPSPVV
1400 1410 1420
>>XP_011521250 (OMIM: 189960,227650,607139) PREDICTED: F (746 aa)
initn: 4850 init1: 4850 opt: 4850 Z-score: 5601.4 bits: 1048.1 E(85289): 0
Smith-Waterman score: 4850; 100.0% identity (100.0% similar) in 741 aa overlap (1-741:1-741)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSIENMGLYEDLSSAGDI
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAFIESLKRADKIPPSLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGEL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLSINTPRLEPREHMAVD
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE5 LLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPH
:::::::::::::::::::::
XP_011 LLLTSFCQNLMAASSVAPPERSMRRC
730 740
>>XP_016878535 (OMIM: 189960,227650,607139) PREDICTED: F (438 aa)
initn: 2688 init1: 2688 opt: 2688 Z-score: 3104.5 bits: 585.3 E(85289): 3.5e-166
Smith-Waterman score: 2688; 100.0% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KE5 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFVLRGFQKNSDLRRTVEPEKMPQVTVDVLQRMLIFALDALAAGVQEESSTHKIVRCWFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFSGHTLGSVISTDPLKRFFSHTLTQILTHSPVLKASDAVQMQREWSFARTHPLLTSLYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEDWVARLMAQAFE
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLFVMLSAEELVGHLQEVLETQEVHWQRVLSFVSALVVCFPEAQQLLEGLLWEHTRLPWL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 SCQLDSMVTAFLVVRQAALEGPSAFLSYADWFKASFGSTRGYHGCSKKALVFLFTFLSEL
XP_016 QQEGPGLPVYVLVRTRAF
430
1455 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:39:23 2016 done: Tue Nov 8 10:39:25 2016
Total Scan time: 12.710 Total Display time: 0.460
Function used was FASTA [36.3.4 Apr, 2011]