Result of FASTA (omim) for
pFN21AE5789
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5789, 616 aa
1>>>pF1KE5789 616 - 616 aa - 616 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.6407+/-0.000516; mu= -11.4292+/- 0.032
mean_var=662.0919+/-140.236, 0's: 0 Z-trim(122.8): 72 B-trim: 1968 in 1/57
Lambda= 0.049844
statistics sampled from 41328 (41420) to 41328 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.486), width: 16
Scan time: 8.750
The best scores are: opt bits E(85289)
NP_056050 (OMIM: 611968) cleavage stimulation fact ( 616) 4237 320.1 1.4e-86
NP_001316 (OMIM: 300907) cleavage stimulation fact ( 577) 2535 197.6 9.6e-50
NP_001293135 (OMIM: 300907) cleavage stimulation f ( 597) 1888 151.1 1e-35
NP_001293138 (OMIM: 300907) cleavage stimulation f ( 560) 1675 135.8 3.9e-31
>>NP_056050 (OMIM: 611968) cleavage stimulation factor s (616 aa)
initn: 4237 init1: 4237 opt: 4237 Z-score: 1675.2 bits: 320.1 E(85289): 1.4e-86
Smith-Waterman score: 4237; 100.0% identity (100.0% similar) in 616 aa overlap (1-616:1-616)
10 20 30 40 50 60
pF1KE5 MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPID
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 HLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 ERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 GPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMET
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 RAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 INIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 INIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQ
550 560 570 580 590 600
610
pF1KE5 SILILKEQIQKSTGAS
::::::::::::::::
NP_056 SILILKEQIQKSTGAS
610
>>NP_001316 (OMIM: 300907) cleavage stimulation factor s (577 aa)
initn: 1812 init1: 1221 opt: 2535 Z-score: 1014.0 bits: 197.6 E(85289): 9.6e-50
Smith-Waterman score: 2813; 69.7% identity (81.0% similar) in 631 aa overlap (1-615:1-576)
10 20 30 40 50 60
pF1KE5 MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYG
:..:.:::::.::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 MAGLTVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPID
::::::::::::::::::::::::::::::::::::::::::::: .::.:.::::. :.
NP_001 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMR
::::::::..:::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 PEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQ
:.:::::::::::. .. :: :. : : : ::: : :: .::::: ::: :
NP_001 IVDPEIALKILHRQTNIPTLIAGNPQ------PVHGAGPG--SGSNVSMNQQNPQAPQAQ
190 200 210 220 230
250 260 270 280 290 300
pF1KE5 HLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPL
:. :. :::::. .:::.:::: .:::: : :::::.:::.:: :.:::: ::: .
NP_001 SLGGMHVNGAPPLMQASMQGGVPAPGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVSM
240 250 260 270 280 290
310 320 330 340 350
pF1KE5 ERGQVQMSDPRAPIPRGPVTPGGLP-PRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPH
::::: :.:::: . :: . :...: ::::::::::::::::::::::::::::::::::
NP_001 ERGQVPMQDPRAAMQRGSL-PANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPH
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 QGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRD-----
:::::::. ::..::: ::.::::: .:: :..::::::.:::: :.:::::::
NP_001 QGPPMHHVPGHESRGPPPHELRGGPLPEPRPLMAEPRGPMLDQRGPPLDGRGGRDPRGID
360 370 380 390 400 410
420 430 440 450 460
pF1KE5 SRAMETRAMETE----------VLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPV
.:.::.::::.. ..:.:.:: :.::. :::.:.::.:::.:::.. ::::
NP_001 ARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMDTRGPV
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE5 PSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQ
:. :::. .:.:::.:::.:: ::: :::: . ::::::::.::
NP_001 PGPRGPIPSGMQGPSPINMGAV-VPQGSRQVPVM---------------QGTGMQGASIQ
480 490 500 510
530 540 550 560 570 580
pF1KE5 GGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVL
:: :::..:::::.::::::.::::::::::
NP_001 GG------------------------------SQPGGFSPGQNQVTPQDHEKAALIMQVL
520 530 540
590 600 610
pF1KE5 QLTADQIAMLPPEQRQSILILKEQIQKSTGAS
:::::::::::::::::::::::::::::::
NP_001 QLTADQIAMLPPEQRQSILILKEQIQKSTGAP
550 560 570
>>NP_001293135 (OMIM: 300907) cleavage stimulation facto (597 aa)
initn: 2453 init1: 1221 opt: 1888 Z-score: 762.4 bits: 151.1 E(85289): 1e-35
Smith-Waterman score: 2763; 67.6% identity (78.5% similar) in 651 aa overlap (1-615:1-596)
10 20 30 40 50 60
pF1KE5 MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYG
:..:.:::::.::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 MAGLTVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPID
::::::::::::::::::::::::::::::::::::::::::::: .::.:.::::. :.
NP_001 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMR
::::::::..:::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 PEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQ
:.:::::::::::. .. :: :. : : : ::: : :: .::::: ::: :
NP_001 IVDPEIALKILHRQTNIPTLIAGNPQ------PVHGAGPG--SGSNVSMNQQNPQAPQAQ
190 200 210 220 230
250 260 270 280 290 300
pF1KE5 HLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPL
:. :. :::::. .:::.:::: .:::: : :::::.:::.:: :.:::: ::: .
NP_001 SLGGMHVNGAPPLMQASMQGGVPAPGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVSM
240 250 260 270 280 290
310 320 330
pF1KE5 ERGQ--------------------VQMSDPRAPIPRGPVTPGGLP-PRGLLGDAPNDPRG
:::: : :.:::: . :: . :...: ::::::::::::::
NP_001 ERGQGTLQHSPVGPAGPASIERVQVPMQDPRAAMQRGSL-PANVPTPRGLLGDAPNDPRG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE5 GTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPM
:::::::::::::::::::::::::::. ::..::: ::.::::: .:: :..::::::
NP_001 GTLLSVTGEVEPRGYLGPPHQGPPMHHVPGHESRGPPPHELRGGPLPEPRPLMAEPRGPM
360 370 380 390 400 410
400 410 420 430 440
pF1KE5 IDQRGLPMDGRGGRD-----SRAMETRAMETE----------VLETRVMERRGMETCAME
.:::: :.::::::: .:.::.::::.. ..:.:.:: :.::. :::
NP_001 LDQRGPPLDGRGGRDPRGIDARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAME
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE5 TRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNP
.:.::.:::.:::.. :::::. :::. .:.:::.:::.:: ::: :::: .
NP_001 ARAMEVRGMEARGMDTRGPVPGPRGPIPSGMQGPSPINMGAV-VPQGSRQVPVM------
480 490 500 510 520
510 520 530 540 550 560
pF1KE5 GAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSP
::::::::.:::: :::..:::
NP_001 ---------QGTGMQGASIQGG------------------------------SQPGGFSP
530 540
570 580 590 600 610
pF1KE5 GQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS
::.::::::.:::::::::::::::::::::::::::::::::::::::::
NP_001 GQNQVTPQDHEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAP
550 560 570 580 590
>>NP_001293138 (OMIM: 300907) cleavage stimulation facto (560 aa)
initn: 1667 init1: 1256 opt: 1675 Z-score: 679.9 bits: 135.8 E(85289): 3.9e-31
Smith-Waterman score: 2726; 68.6% identity (79.2% similar) in 631 aa overlap (1-615:1-559)
10 20 30 40 50 60
pF1KE5 MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYG
:..:.:::::.::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 MAGLTVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPID
::::::::::::::::::::::::::::::::::::::::::::: .::.:.::::. :.
NP_001 FCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 PEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMR
::::::::..:::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 PEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 IMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQ
:.:::::::::::. .. :: :. : : : ::: : :: .::::: ::: :
NP_001 IVDPEIALKILHRQTNIPTLIAGNPQ------PVHGAGPG--SGSNVSMNQQNPQAPQAQ
190 200 210 220 230
250 260 270 280 290 300
pF1KE5 HLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPL
: ::.:::: .:::: : :::::.:::.:: :.:::: ::: .
NP_001 SL-----------------GGVPAPGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVSM
240 250 260 270
310 320 330 340 350
pF1KE5 ERGQVQMSDPRAPIPRGPVTPGGLP-PRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPH
::::: :.:::: . :: . :...: ::::::::::::::::::::::::::::::::::
NP_001 ERGQVPMQDPRAAMQRGSL-PANVPTPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPH
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE5 QGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRD-----
:::::::. ::..::: ::.::::: .:: :..::::::.:::: :.:::::::
NP_001 QGPPMHHVPGHESRGPPPHELRGGPLPEPRPLMAEPRGPMLDQRGPPLDGRGGRDPRGID
340 350 360 370 380 390
420 430 440 450 460
pF1KE5 SRAMETRAMETE----------VLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPV
.:.::.::::.. ..:.:.:: :.::. :::.:.::.:::.:::.. ::::
NP_001 ARGMEARAMEARGLDARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMDTRGPV
400 410 420 430 440 450
470 480 490 500 510 520
pF1KE5 PSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQ
:. :::. .:.:::.:::.:: ::: :::: . ::::::::.::
NP_001 PGPRGPIPSGMQGPSPINMGAV-VPQGSRQVPVM---------------QGTGMQGASIQ
460 470 480 490
530 540 550 560 570 580
pF1KE5 GGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVL
:: :::..:::::.::::::.::::::::::
NP_001 GG------------------------------SQPGGFSPGQNQVTPQDHEKAALIMQVL
500 510 520
590 600 610
pF1KE5 QLTADQIAMLPPEQRQSILILKEQIQKSTGAS
:::::::::::::::::::::::::::::::
NP_001 QLTADQIAMLPPEQRQSILILKEQIQKSTGAP
530 540 550 560
616 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:40:17 2016 done: Tue Nov 8 06:40:18 2016
Total Scan time: 8.750 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]