Result of FASTA (omim) for
pFN21AE5784
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5784, 698 aa
1>>>pF1KE5784 698 - 698 aa - 698 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2107+/-0.000388; mu= 6.2160+/- 0.024
mean_var=176.8272+/-35.596, 0's: 0 Z-trim(118.2): 12 B-trim: 92 in 1/56
Lambda= 0.096449
statistics sampled from 30939 (30951) to 30939 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.363), width: 16
Scan time: 9.490
The best scores are: opt bits E(85289)
NP_001257952 (OMIM: 606605) ATR-interacting protei ( 698) 4622 656.0 1.4e-187
NP_569055 (OMIM: 606605) ATR-interacting protein i ( 791) 4622 656.0 1.6e-187
NP_001257951 (OMIM: 606605) ATR-interacting protei ( 664) 4405 625.8 1.7e-178
NP_115542 (OMIM: 606605) ATR-interacting protein i ( 764) 3716 529.9 1.3e-149
>>NP_001257952 (OMIM: 606605) ATR-interacting protein is (698 aa)
initn: 4622 init1: 4622 opt: 4622 Z-score: 3488.6 bits: 656.0 E(85289): 1.4e-187
Smith-Waterman score: 4622; 99.9% identity (100.0% similar) in 698 aa overlap (1-698:1-698)
10 20 30 40 50 60
pF1KE5 MSKNPSGKNRETVPIKDNFELEVLQAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSKNPSGKNRETVPIKDNFELEVLQAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SVLEEQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVLEEQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERAN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLAAPSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTESGYKPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLAAPSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTESGYKPLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GREDSKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GREDSKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SSSSESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 CSRDGDPAEGGRRAFPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSRDGDPAEGGRRAFPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SCVSSGVETNPEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCVSSGVETNPEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 VHRLSDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHRLSDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 NTSCDFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTSCDFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 LLYMYITSRPDRVALETQWLQLEQEVVWLLAKLGVQSPLPPVTGSNCQCNVEVIRALTVM
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_001 LLYMYITSRPDRVALETQWLQLEQEVVWLLAKLGVQSPLPPVTGSNCQCNVEVVRALTVM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 LHRQWLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHRQWLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMP
610 620 630 640 650 660
670 680 690
pF1KE5 GVSMLIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG
::::::::::::::::::::::::::::::::::::::
NP_001 GVSMLIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG
670 680 690
>>NP_569055 (OMIM: 606605) ATR-interacting protein isofo (791 aa)
initn: 4622 init1: 4622 opt: 4622 Z-score: 3487.8 bits: 656.0 E(85289): 1.6e-187
Smith-Waterman score: 4622; 99.9% identity (100.0% similar) in 698 aa overlap (1-698:94-791)
10 20 30
pF1KE5 MSKNPSGKNRETVPIKDNFELEVLQAQYKE
::::::::::::::::::::::::::::::
NP_569 DTLASQALSQCPAAARDVSSDHKVHRLLDGMSKNPSGKNRETVPIKDNFELEVLQAQYKE
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 LKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSK
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE5 KLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFG
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE5 KTSFPTKESFSANMSLPHPCQTESGYKPLVGREDSKPHSLRGDSIKQEEAQKSFVDSWRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KTSFPTKESFSANMSLPHPCQTESGYKPLVGREDSKPHSLRGDSIKQEEAQKSFVDSWRQ
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE5 RSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFGSTLAGMSGLRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 RSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFGSTLAGMSGLRTT
310 320 330 340 350 360
280 290 300 310 320 330
pF1KE5 GSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRAFPLCQLPGAVHFLPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 GSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRAFPLCQLPGAVHFLPLV
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE5 QFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVTALSILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 QFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVTALSILQ
430 440 450 460 470 480
400 410 420 430 440 450
pF1KE5 HLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 HLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLL
490 500 510 520 530 540
460 470 480 490 500 510
pF1KE5 HLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 HLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSV
550 560 570 580 590 600
520 530 540 550 560 570
pF1KE5 LLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVWLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 LLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVWLL
610 620 630 640 650 660
580 590 600 610 620 630
pF1KE5 AKLGVQSPLPPVTGSNCQCNVEVIRALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDT
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_569 AKLGVQSPLPPVTGSNCQCNVEVVRALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDT
670 680 690 700 710 720
640 650 660 670 680 690
pF1KE5 VLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 VLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETDV
730 740 750 760 770 780
pF1KE5 EDPEVECG
::::::::
NP_569 EDPEVECG
790
>>NP_001257951 (OMIM: 606605) ATR-interacting protein is (664 aa)
initn: 4405 init1: 4405 opt: 4405 Z-score: 3325.7 bits: 625.8 E(85289): 1.7e-178
Smith-Waterman score: 4405; 99.8% identity (100.0% similar) in 664 aa overlap (35-698:1-664)
10 20 30 40 50 60
pF1KE5 PSGKNRETVPIKDNFELEVLQAQYKELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLE
::::::::::::::::::::::::::::::
NP_001 MKVMEEEVLIKNGEIKILRDSLHQTESVLE
10 20 30
70 80 90 100 110 120
pF1KE5 EQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSERANKLAA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 PSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTESGYKPLVGRED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVSHVSPRKNPSVVIKPEACSPQFGKTSFPTKESFSANMSLPHPCQTESGYKPLVGRED
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 SKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKPHSLRGDSIKQEEAQKSFVDSWRQRSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 ESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNECSRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESPAGTPLQPPGFGSTLAGMSGLRTTGSYDGSFSLSALREAQNLAFTGLNLVARNECSRD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 GDPAEGGRRAFPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDPAEGGRRAFPLCQLPGAVHFLPLVQFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE5 SGVETNPEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGVETNPEDSVCILEGFSVTALSILQHLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE5 SDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDGDMTSALRGVADDQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSC
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE5 DFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFLPRFQCVFQVLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYM
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE5 YITSRPDRVALETQWLQLEQEVVWLLAKLGVQSPLPPVTGSNCQCNVEVIRALTVMLHRQ
:::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::
NP_001 YITSRPDRVALETQWLQLEQEVVWLLAKLGVQSPLPPVTGSNCQCNVEVVRALTVMLHRQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE5 WLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLTVRRAGGPPRTDQQRRTVRCLRDTVLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSM
580 590 600 610 620 630
670 680 690
pF1KE5 LIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG
::::::::::::::::::::::::::::::::::
NP_001 LIRGLPDVTDCEEAALDDLCAAETDVEDPEVECG
640 650 660
>>NP_115542 (OMIM: 606605) ATR-interacting protein isofo (764 aa)
initn: 3711 init1: 3711 opt: 3716 Z-score: 2806.7 bits: 529.9 E(85289): 1.3e-149
Smith-Waterman score: 4367; 96.1% identity (96.1% similar) in 698 aa overlap (1-698:94-764)
10 20 30
pF1KE5 MSKNPSGKNRETVPIKDNFELEVLQAQYKE
::::::::::::::::::::::::::::::
NP_115 DTLASQALSQCPAAARDVSSDHKVHRLLDGMSKNPSGKNRETVPIKDNFELEVLQAQYKE
70 80 90 100 110 120
40 50 60 70 80 90
pF1KE5 LKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSK
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE5 KLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KLQSLQSELQFKDAEMNELRTKLQTSERANKLAAPSVSHVSPRKNPSVVIKPEACSPQFG
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE5 KTSFPTKESFSANMSLPHPCQTESGYKPLVGREDSKPHSLRGDSIKQEEAQKSFVDSWRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KTSFPTKESFSANMSLPHPCQTESGYKPLVGREDSKPHSLRGDSIKQEEAQKSFVDSWRQ
250 260 270 280 290 300
220 230 240 250 260 270
pF1KE5 RSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFGSTLAGMSGLRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RSNTQGSILINLLLKQPLIPGSSLSLCHLLSSSSESPAGTPLQPPGFGSTLAGMSGLRTT
310 320 330 340 350 360
280 290 300 310 320 330
pF1KE5 GSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRAFPLCQLPGAVHFLPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GSYDGSFSLSALREAQNLAFTGLNLVARNECSRDGDPAEGGRRAFPLCQLPGAVHFLPLV
370 380 390 400 410 420
340 350 360 370 380 390
pF1KE5 QFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVTALSILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QFFIGLHCQALQDLAAAKRSGAPGDSPTHSSCVSSGVETNPEDSVCILEGFSVTALSILQ
430 440 450 460 470 480
400 410 420 430 440 450
pF1KE5 HLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 HLVCHSGAVVSLLLSGVGADSAAGEGNRSLVHRLSDGDMTSALRGVADDQGQHPLLKMLL
490 500 510 520 530 540
460 470 480 490 500 510
pF1KE5 HLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 HLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFLPRFQCVFQVLPKCLSPETPLPSV
550 560 570 580 590 600
520 530 540 550 560 570
pF1KE5 LLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVVWLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LLAVELLSLLADHDQLAPQLCSHSEGCLLLLLYMYITSRPDRVALETQWLQLEQEVV---
610 620 630 640 650 660
580 590 600 610 620 630
pF1KE5 AKLGVQSPLPPVTGSNCQCNVEVIRALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDT
::::::::::::::::::::::::::::::::::::
NP_115 ------------------------RALTVMLHRQWLTVRRAGGPPRTDQQRRTVRCLRDT
670 680 690
640 650 660 670 680 690
pF1KE5 VLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VLLLHGLSQKDKLFMMHCVEVLHQFDQVMPGVSMLIRGLPDVTDCEEAALDDLCAAETDV
700 710 720 730 740 750
pF1KE5 EDPEVECG
::::::::
NP_115 EDPEVECG
760
698 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:37:31 2016 done: Tue Nov 8 06:37:32 2016
Total Scan time: 9.490 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]