Result of FASTA (omim) for
pFN21AE5783
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5783, 681 aa
1>>>pF1KE5783 681 - 681 aa - 681 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9084+/-0.000396; mu= 8.1033+/- 0.025
mean_var=150.7867+/-31.174, 0's: 0 Z-trim(117.5): 98 B-trim: 14 in 1/55
Lambda= 0.104446
statistics sampled from 29476 (29577) to 29476 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.347), width: 16
Scan time: 7.860
The best scores are: opt bits E(85289)
NP_060167 (OMIM: 612959) epithelial splicing regul ( 681) 4585 703.1 8.9e-202
NP_001030087 (OMIM: 612959) epithelial splicing re ( 677) 4533 695.2 2e-199
XP_005251048 (OMIM: 612959) PREDICTED: epithelial ( 663) 4416 677.6 4e-194
NP_001116298 (OMIM: 612959) epithelial splicing re ( 659) 4364 669.8 9.2e-192
XP_005251049 (OMIM: 612959) PREDICTED: epithelial ( 636) 4074 626.1 1.3e-178
NP_001116297 (OMIM: 612959) epithelial splicing re ( 608) 4070 625.4 1.9e-178
NP_001116299 (OMIM: 612959) epithelial splicing re ( 604) 4018 617.6 4.2e-176
NP_079215 (OMIM: 612960) epithelial splicing regul ( 717) 2636 409.4 2.4e-113
XP_005256210 (OMIM: 612960) PREDICTED: epithelial ( 716) 2619 406.8 1.4e-112
XP_006721336 (OMIM: 612960) PREDICTED: epithelial ( 591) 2352 366.6 1.5e-100
XP_011521640 (OMIM: 612960) PREDICTED: epithelial ( 591) 2352 366.6 1.5e-100
XP_011530199 (OMIM: 604851) PREDICTED: G-rich sequ ( 318) 356 65.6 3.2e-10
NP_001091947 (OMIM: 604851) G-rich sequence factor ( 318) 356 65.6 3.2e-10
XP_006714926 (OMIM: 601035) PREDICTED: heterogeneo ( 429) 240 48.2 7.5e-05
XP_016864908 (OMIM: 601035) PREDICTED: heterogeneo ( 429) 240 48.2 7.5e-05
XP_016864907 (OMIM: 601035) PREDICTED: heterogeneo ( 439) 240 48.2 7.7e-05
NP_001244222 (OMIM: 601035) heterogeneous nuclear ( 449) 240 48.2 7.8e-05
XP_016864906 (OMIM: 601035) PREDICTED: heterogeneo ( 449) 240 48.2 7.8e-05
NP_005511 (OMIM: 601035) heterogeneous nuclear rib ( 449) 240 48.2 7.8e-05
XP_016864904 (OMIM: 601035) PREDICTED: heterogeneo ( 449) 240 48.2 7.8e-05
XP_016864905 (OMIM: 601035) PREDICTED: heterogeneo ( 449) 240 48.2 7.8e-05
XP_006714925 (OMIM: 601035) PREDICTED: heterogeneo ( 452) 240 48.2 7.8e-05
XP_016864903 (OMIM: 601035) PREDICTED: heterogeneo ( 452) 240 48.2 7.8e-05
XP_011532849 (OMIM: 601035) PREDICTED: heterogeneo ( 462) 240 48.3 8e-05
XP_011532848 (OMIM: 601035) PREDICTED: heterogeneo ( 472) 240 48.3 8.1e-05
XP_005265952 (OMIM: 601035) PREDICTED: heterogeneo ( 472) 240 48.3 8.1e-05
XP_011532847 (OMIM: 601035) PREDICTED: heterogeneo ( 472) 240 48.3 8.1e-05
XP_011532846 (OMIM: 601035) PREDICTED: heterogeneo ( 472) 240 48.3 8.1e-05
XP_005265953 (OMIM: 601035) PREDICTED: heterogeneo ( 472) 240 48.3 8.1e-05
XP_011532844 (OMIM: 601035) PREDICTED: heterogeneo ( 472) 240 48.3 8.1e-05
NP_001309369 (OMIM: 602324) heterogeneous nuclear ( 331) 236 47.6 9.2e-05
NP_067676 (OMIM: 602324) heterogeneous nuclear rib ( 331) 236 47.6 9.2e-05
NP_001309367 (OMIM: 602324) heterogeneous nuclear ( 331) 236 47.6 9.2e-05
NP_001309370 (OMIM: 602324) heterogeneous nuclear ( 331) 236 47.6 9.2e-05
NP_001309368 (OMIM: 602324) heterogeneous nuclear ( 331) 236 47.6 9.2e-05
NP_001309372 (OMIM: 602324) heterogeneous nuclear ( 340) 236 47.6 9.4e-05
NP_001309371 (OMIM: 602324) heterogeneous nuclear ( 340) 236 47.6 9.4e-05
XP_016871657 (OMIM: 602324) PREDICTED: heterogeneo ( 346) 236 47.6 9.6e-05
NP_001309363 (OMIM: 602324) heterogeneous nuclear ( 346) 236 47.6 9.6e-05
NP_036339 (OMIM: 602324) heterogeneous nuclear rib ( 346) 236 47.6 9.6e-05
NP_001309365 (OMIM: 602324) heterogeneous nuclear ( 346) 236 47.6 9.6e-05
NP_001309366 (OMIM: 602324) heterogeneous nuclear ( 346) 236 47.6 9.6e-05
NP_062543 (OMIM: 300610,300986) heterogeneous nucl ( 449) 237 47.8 0.00011
NP_001027565 (OMIM: 300610,300986) heterogeneous n ( 449) 237 47.8 0.00011
NP_004957 (OMIM: 601037) heterogeneous nuclear rib ( 415) 229 46.6 0.00023
NP_001091676 (OMIM: 601037) heterogeneous nuclear ( 415) 229 46.6 0.00023
NP_001091675 (OMIM: 601037) heterogeneous nuclear ( 415) 229 46.6 0.00023
NP_001091674 (OMIM: 601037) heterogeneous nuclear ( 415) 229 46.6 0.00023
NP_001091678 (OMIM: 601037) heterogeneous nuclear ( 415) 229 46.6 0.00023
NP_001091677 (OMIM: 601037) heterogeneous nuclear ( 415) 229 46.6 0.00023
>>NP_060167 (OMIM: 612959) epithelial splicing regulator (681 aa)
initn: 4585 init1: 4585 opt: 4585 Z-score: 3743.5 bits: 703.1 E(85289): 8.9e-202
Smith-Waterman score: 4585; 100.0% identity (100.0% similar) in 681 aa overlap (1-681:1-681)
10 20 30 40 50 60
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
610 620 630 640 650 660
670 680
pF1KE5 EDGLIHTNDQARTLPKEWVCI
:::::::::::::::::::::
NP_060 EDGLIHTNDQARTLPKEWVCI
670 680
>>NP_001030087 (OMIM: 612959) epithelial splicing regula (677 aa)
initn: 3665 init1: 3665 opt: 4533 Z-score: 3701.2 bits: 695.2 E(85289): 2e-199
Smith-Waterman score: 4533; 99.4% identity (99.4% similar) in 681 aa overlap (1-681:1-677)
10 20 30 40 50 60
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSPPPC----LSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
550 560 570 580 590
610 620 630 640 650 660
pF1KE5 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
600 610 620 630 640 650
670 680
pF1KE5 EDGLIHTNDQARTLPKEWVCI
:::::::::::::::::::::
NP_001 EDGLIHTNDQARTLPKEWVCI
660 670
>>XP_005251048 (OMIM: 612959) PREDICTED: epithelial spli (663 aa)
initn: 4416 init1: 4416 opt: 4416 Z-score: 3606.0 bits: 677.6 E(85289): 4e-194
Smith-Waterman score: 4416; 100.0% identity (100.0% similar) in 657 aa overlap (1-657:1-657)
10 20 30 40 50 60
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQCLK
610 620 630 640 650 660
670 680
pF1KE5 EDGLIHTNDQARTLPKEWVCI
XP_005 DVW
>>NP_001116298 (OMIM: 612959) epithelial splicing regula (659 aa)
initn: 3665 init1: 3665 opt: 4364 Z-score: 3563.7 bits: 669.8 E(85289): 9.2e-192
Smith-Waterman score: 4364; 99.4% identity (99.4% similar) in 657 aa overlap (1-657:1-653)
10 20 30 40 50 60
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSPPPC----LSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
550 560 570 580 590
610 620 630 640 650 660
pF1KE5 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQCLK
600 610 620 630 640 650
670 680
pF1KE5 EDGLIHTNDQARTLPKEWVCI
NP_001 DVW
>>XP_005251049 (OMIM: 612959) PREDICTED: epithelial spli (636 aa)
initn: 4070 init1: 4070 opt: 4074 Z-score: 3327.8 bits: 626.1 E(85289): 1.3e-178
Smith-Waterman score: 4074; 96.5% identity (97.3% similar) in 636 aa overlap (1-636:1-632)
10 20 30 40 50 60
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
::::::: .: : : . :. :. : : .
XP_005 YTAYYPSM--QPRMDLY--TQMTRPGLYPKNGFVFKGPSS
610 620 630
670 680
pF1KE5 EDGLIHTNDQARTLPKEWVCI
>>NP_001116297 (OMIM: 612959) epithelial splicing regula (608 aa)
initn: 4070 init1: 4070 opt: 4070 Z-score: 3324.8 bits: 625.4 E(85289): 1.9e-178
Smith-Waterman score: 4070; 100.0% identity (100.0% similar) in 607 aa overlap (1-607:1-607)
10 20 30 40 50 60
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
:::::::
NP_001 YTAYYPSV
>>NP_001116299 (OMIM: 612959) epithelial splicing regula (604 aa)
initn: 3661 init1: 3661 opt: 4018 Z-score: 3282.5 bits: 617.6 E(85289): 4.2e-176
Smith-Waterman score: 4018; 99.3% identity (99.3% similar) in 607 aa overlap (1-607:1-603)
10 20 30 40 50 60
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVVDLANKKVGQLHEVLVRPDQLEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGIL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GLSPPPCKLPCLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
:::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSPPP----CLSPPSYTFPAPAAVIPTEAAIYQPSVILNPRALQPSTAYYPAGTQLFMN
550 560 570 580 590
610 620 630 640 650 660
pF1KE5 YTAYYPSPPGSPNSLGYFPTAANLSGVPPQPGTVVRMQGLAYNTGVKEILNFFQGYQYAT
:::::::
NP_001 YTAYYPSV
600
>>NP_079215 (OMIM: 612960) epithelial splicing regulator (717 aa)
initn: 2696 init1: 1779 opt: 2636 Z-score: 2156.0 bits: 409.4 E(85289): 2.4e-113
Smith-Waterman score: 2785; 60.2% identity (82.1% similar) in 694 aa overlap (5-681:27-717)
10 20 30
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVV
: :::::: :::: : ::::: .:::: :.::
NP_079 MTPPPPPPPPPGPDPAADPAADPCPWPGSLVVLFGATAGALGRDLGSDETDLILLVWQVV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 DLANKKVGQLHEVLVRPDQLELTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNI
. ...:: ::. ::: . :. .:.: . ....::. : ::..:.::.: :.... .
NP_079 EPRSRQVGTLHKSLVRAEAAALSTQCREASGLSADSLARAEPLDKVLQQFSQLVNGDVAL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 GVGTSFCLCTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDV
: . :::::: .::.::::::.::..::. :.::.:::.::. :.. : :
NP_079 LGGGPYMLCTDGQQLLRQVLHPEASRKNLVLPDMFFSFYDLRREFHMQHPSTCPARDLTV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 ATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKM
:::.. :..: ... . .:. .:. : .:: ...:: .. :: :: .. :.:.: :::
NP_079 ATMAQGLGLETDATEDDFGVWEVKTMVAVILHLLKEPSSQLFSKPEVIKQKYETGPCSKA
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 ELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEH
...:..::::::::::::::::.::::::::.:.::.:::::::::::::::.:::. :.
NP_079 DVVDSETVVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQ
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 RDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTAT
:::::::::::::.:::::::::::.:.::::::: :::.:::.:.:::.:.:::::.:
NP_079 RDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 AEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRY
.:..:.: .::.::: ::.::: .::::::::::.:::::: :: :::.:: .:::::
NP_079 PTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRY
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE5 IELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATI
:::::::::::::::::..:.::.: : :..:. : ..: :. :::.:::::::.:::
NP_079 IELFRSTAAEVQQVLNRYASGPLLPTLTAPLLPI-PFPLAPGTG-RDCVRLRGLPYTATI
430 440 450 460 470
460 470 480 490 500 510
pF1KE5 EDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYV
::::.:::: :.::: ::::::::.:::::::::::: ::.::. :::.:::: ::.:::
NP_079 EDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQRCHKKVMKERYV
480 490 500 510 520 530
520 530 540 550 560 570
pF1KE5 EVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYT-FPAPAAVIPTEAAIYQPSV
:: ::.:::. :::::::.:.:.:::::::::::::.:: : : ..::::.: ::
NP_079 EVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPPTYTTFQATPTLIPTETAALYPSS
540 550 560 570 580 590
580 590 600 610 620
pF1KE5 ILNPRALQPST----AYYPA-GTQLFMNYTAYYPSPPGSPNSLGYF--PTAANLSGVPP-
: : : :.. ::::. .:::..:::::::::: ::...::. :::: :...:
NP_079 ALLPAARVPAAPTPVAYYPGPATQLYLNYTAYYPSPPVSPTTVGYLTTPTAA-LASAPTS
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE5 ---QPGTVVRMQGLAYNTGVKEILNFFQGYQYATED--GLIHTNDQARTL---PKEWVCI
: :..:::::. :..:.:..:. ::.:: ..: .:. ..: ::. ::::::.
NP_079 VLSQSGALVRMQGVPYTAGMKDLLSVFQAYQLPADDYTSLMPVGDPPRTVLQAPKEWVCL
660 670 680 690 700 710
>>XP_005256210 (OMIM: 612960) PREDICTED: epithelial spli (716 aa)
initn: 2677 init1: 1148 opt: 2619 Z-score: 2142.1 bits: 406.8 E(85289): 1.4e-112
Smith-Waterman score: 2768; 60.1% identity (82.0% similar) in 694 aa overlap (5-681:27-716)
10 20 30
pF1KE5 MTASPDYLVVLFGITAGATGAKLGSDEKELILLFWKVV
: :::::: :::: : ::::: .:::: :.::
XP_005 MTPPPPPPPPPGPDPAADPAADPCPWPGSLVVLFGATAGALGRDLGSDETDLILLVWQVV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 DLANKKVGQLHEVLVRPDQLELTEDCKEETKIDVESLSSASQLDQALRQFNQSVSNELNI
. ...:: ::. ::: . :. .:.: . ....::. : ::..:.::.: :.... .
XP_005 EPRSRQVGTLHKSLVRAEAAALSTQCREASGLSADSLARAEPLDKVLQQFSQLVNGDVAL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 GVGTSFCLCTDGQLHVRQILHPEASKKNVLLPECFYSFFDLRKEFKKCCPGSPDIDKLDV
: . :::::: .::.::::::.::..::. :.::.:::.::. :.. : :
XP_005 LGGGPYMLCTDGQQLLRQVLHPEASRKNLVLPDMFFSFYDLRREFHMQHPSTCPARDLTV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 ATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEPYNHRFSDPERVNYKFESGTCSKM
:::.. :..: ... . .:. .:. : .:: ...:: .. :: :: .. :.:.: : :
XP_005 ATMAQGLGLETDATEDDFGVWEVKTMVAVILHLLKEPSSQLFSKPEVIKQKYETGPC-KA
190 200 210 220 230
220 230 240 250 260 270
pF1KE5 ELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGAALCLNAQGRRNGEALVRFVSEEH
...:..::::::::::::::::.::::::::.:.::.:::::::::::::::.:::. :.
XP_005 DVVDSETVVRARGLPWQSSDQDVARFFKGLNVARGGVALCLNAQGRRNGEALIRFVDSEQ
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE5 RDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNEVAQFLSKENQVIVRMRGLPFTAT
:::::::::::::.:::::::::::.:.::::::: :::.:::.:.:::.:.:::::.:
XP_005 RDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE5 AEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFVLFACEEYAQNALRKHKDLLGKRY
.:..:.: .::.::: ::.::: .::::::::::.:::::: :: :::.:: .:::::
XP_005 PTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRY
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE5 IELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQQFVPPTNVRDCIRLRGLPYAATI
:::::::::::::::::..:.::.: : :..:. : ..: :. :::.:::::::.:::
XP_005 IELFRSTAAEVQQVLNRYASGPLLPTLTAPLLPI-PFPLAPGTG-RDCVRLRGLPYTATI
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE5 EDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQMKSADRAFMAAQKCHKKNMKDRYV
::::.:::: :.::: ::::::::.:::::::::::: ::.::. :::.:::: ::.:::
XP_005 EDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQRCHKKVMKERYV
480 490 500 510 520 530
520 530 540 550 560 570
pF1KE5 EVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPPSYT-FPAPAAVIPTEAAIYQPSV
:: ::.:::. :::::::.:.:.:::::::::::::.:: : : ..::::.: ::
XP_005 EVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPPTYTTFQATPTLIPTETAALYPSS
540 550 560 570 580 590
580 590 600 610 620
pF1KE5 ILNPRALQPST----AYYPA-GTQLFMNYTAYYPSPPGSPNSLGYF--PTAANLSGVPP-
: : : :.. ::::. .:::..:::::::::: ::...::. :::: :...:
XP_005 ALLPAARVPAAPTPVAYYPGPATQLYLNYTAYYPSPPVSPTTVGYLTTPTAA-LASAPTS
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE5 ---QPGTVVRMQGLAYNTGVKEILNFFQGYQYATED--GLIHTNDQARTL---PKEWVCI
: :..:::::. :..:.:..:. ::.:: ..: .:. ..: ::. ::::::.
XP_005 VLSQSGALVRMQGVPYTAGMKDLLSVFQAYQLPADDYTSLMPVGDPPRTVLQAPKEWVCL
660 670 680 690 700 710
>>XP_006721336 (OMIM: 612960) PREDICTED: epithelial spli (591 aa)
initn: 2412 init1: 1495 opt: 2352 Z-score: 1925.9 bits: 366.6 E(85289): 1.5e-100
Smith-Waterman score: 2501; 62.9% identity (84.0% similar) in 593 aa overlap (106-681:2-591)
80 90 100 110 120 130
pF1KE5 SSASQLDQALRQFNQSVSNELNIGVGTSFCLCTDGQLHVRQILHPEASKKNVLLPECFYS
:::::: .::.::::::.::..::. :.:
XP_006 MLCTDGQQLLRQVLHPEASRKNLVLPDMFFS
10 20 30
140 150 160 170 180 190
pF1KE5 FFDLRKEFKKCCPGSPDIDKLDVATMTEYLNFEKSSSVSRYGASQVEDMGNIILAMISEP
:.:::.::. :.. : ::::.. :..: ... . .:. .:. : .:: ...::
XP_006 FYDLRREFHMQHPSTCPARDLTVATMAQGLGLETDATEDDFGVWEVKTMVAVILHLLKEP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE5 YNHRFSDPERVNYKFESGTCSKMELIDDNTVVRARGLPWQSSDQDIARFFKGLNIAKGGA
.. :: :: .. :.:.: ::: ...:..::::::::::::::::.::::::::.:.::.
XP_006 SSQLFSKPEVIKQKYETGPCSKADVVDSETVVRARGLPWQSSDQDVARFFKGLNVARGGV
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE5 ALCLNAQGRRNGEALVRFVSEEHRDLALQRHKHHMGTRYIEVYKATGEDFLKIAGGTSNE
:::::::::::::::.:::. :.:::::::::::::.:::::::::::.:.::::::: :
XP_006 ALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE5 VAQFLSKENQVIVRMRGLPFTATAEEVVAFFGQHCPITGGKEGILFVTYPDGRPTGDAFV
::.:::.:.:::.:.:::::.: .:..:.: .::.::: ::.::: .::::::::::.
XP_006 VARFLSREDQVILRLRGLPFSAGPTDVLGFLGPECPVTGGTEGLLFVRHPDGRPTGDAFA
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE5 LFACEEYAQNALRKHKDLLGKRYIELFRSTAAEVQQVLNRFSSAPLIPLPTPPIIPVLPQ
:::::: :: :::.:: .::::::::::::::::::::::..:.::.: : :..:. :
XP_006 LFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYASGPLLPTLTAPLLPI-PF
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE5 QFVPPTNVRDCIRLRGLPYAATIEDILDFLGEFATDIRTHGVHMVLNHQGRPSGDAFIQM
..: :. :::.:::::::.:::::::.:::: :.::: ::::::::.::::::::::::
XP_006 PLAPGTG-RDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQM
340 350 360 370 380
500 510 520 530 540 550
pF1KE5 KSADRAFMAAQKCHKKNMKDRYVEVFQCSAEEMNFVLMGGTLNRNGLSPPPCKLPCLSPP
::.::. :::.:::: ::.::::: ::.:::. :::::::.:.:.:::::::::::::
XP_006 TSAERALAAAQRCHKKVMKERYVEVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPP
390 400 410 420 430 440
560 570 580 590 600
pF1KE5 SYT-FPAPAAVIPTEAAIYQPSVILNPRALQPST----AYYPA-GTQLFMNYTAYYPSPP
.:: : : ..::::.: :: : : : :.. ::::. .:::..::::::::::
XP_006 TYTTFQATPTLIPTETAALYPSSALLPAARVPAAPTPVAYYPGPATQLYLNYTAYYPSPP
450 460 470 480 490 500
610 620 630 640 650 660
pF1KE5 GSPNSLGYF--PTAANLSGVPP----QPGTVVRMQGLAYNTGVKEILNFFQGYQYATED-
::...::. :::: :...: : :..:::::. :..:.:..:. ::.:: ..:
XP_006 VSPTTVGYLTTPTAA-LASAPTSVLSQSGALVRMQGVPYTAGMKDLLSVFQAYQLPADDY
510 520 530 540 550 560
670 680
pF1KE5 -GLIHTNDQARTL---PKEWVCI
.:. ..: ::. ::::::.
XP_006 TSLMPVGDPPRTVLQAPKEWVCL
570 580 590
681 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:36:51 2016 done: Tue Nov 8 06:36:52 2016
Total Scan time: 7.860 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]