Result of FASTA (omim) for
pFN21AE5758
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5758, 779 aa
1>>>pF1KE5758 779 - 779 aa - 779 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4277+/-0.000505; mu= 19.7343+/- 0.032
mean_var=70.5362+/-14.588, 0's: 0 Z-trim(107.6): 47 B-trim: 559 in 1/52
Lambda= 0.152710
statistics sampled from 15649 (15690) to 15649 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.52), E-opt: 0.2 (0.184), width: 16
Scan time: 9.630
The best scores are: opt bits E(85289)
NP_001129406 (OMIM: 608777) periostin isoform 2 pr ( 779) 5041 1120.8 0
NP_001129408 (OMIM: 608777) periostin isoform 4 pr ( 751) 4697 1045.0 0
NP_001129407 (OMIM: 608777) periostin isoform 3 pr ( 781) 4584 1020.1 0
NP_001273594 (OMIM: 608777) periostin isoform 5 pr ( 809) 4421 984.2 0
NP_001273595 (OMIM: 608777) periostin isoform 6 pr ( 749) 4403 980.2 0
NP_001317446 (OMIM: 608777) periostin isoform 8 pr ( 808) 4391 977.6 0
XP_016875845 (OMIM: 608777) PREDICTED: periostin i ( 812) 4391 977.6 0
XP_016875844 (OMIM: 608777) PREDICTED: periostin i ( 817) 4391 977.6 0
NP_006466 (OMIM: 608777) periostin isoform 1 precu ( 836) 4391 977.6 0
XP_005266289 (OMIM: 608777) PREDICTED: periostin i ( 806) 4390 977.4 0
NP_001273596 (OMIM: 608777) periostin isoform 7 pr ( 721) 4377 974.5 0
NP_000349 (OMIM: 121820,121900,122200,601692,60208 ( 683) 1996 449.9 1.7e-125
XP_011536844 (OMIM: 608561) PREDICTED: stabilin-2 (1238) 183 50.6 4.8e-05
XP_011536843 (OMIM: 608561) PREDICTED: stabilin-2 (1684) 183 50.7 6.2e-05
XP_011536841 (OMIM: 608561) PREDICTED: stabilin-2 (1994) 183 50.7 7.1e-05
XP_011536840 (OMIM: 608561) PREDICTED: stabilin-2 (2242) 183 50.8 7.8e-05
XP_016875074 (OMIM: 608561) PREDICTED: stabilin-2 (2246) 183 50.8 7.8e-05
XP_011536839 (OMIM: 608561) PREDICTED: stabilin-2 (2283) 183 50.8 8e-05
NP_060034 (OMIM: 608561) stabilin-2 precursor [Hom (2551) 183 50.8 8.7e-05
>>NP_001129406 (OMIM: 608777) periostin isoform 2 precur (779 aa)
initn: 5041 init1: 5041 opt: 5041 Z-score: 5998.9 bits: 1120.8 E(85289): 0
Smith-Waterman score: 5041; 100.0% identity (100.0% similar) in 779 aa overlap (1-779:1-779)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 FKEIPVTVYKPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKEIPVTVYKPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLK
670 680 690 700 710 720
730 740 750 760 770
pF1KE5 KLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
730 740 750 760 770
>>NP_001129408 (OMIM: 608777) periostin isoform 4 precur (751 aa)
initn: 4957 init1: 4694 opt: 4697 Z-score: 5589.5 bits: 1045.0 E(85289): 0
Smith-Waterman score: 4794; 96.4% identity (96.4% similar) in 779 aa overlap (1-779:1-751)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 FKEIPVTVYKPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKEIPVTVYKPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLK
670 680 690 700 710 720
730 740 750 760 770
pF1KE5 KLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
::::: ::::::::::::::::::::::::::
NP_001 KLLQE----------------------------DTPVRKLQANKKVQGSRRRLREGRSQ
730 740 750
>>NP_001129407 (OMIM: 608777) periostin isoform 3 precur (781 aa)
initn: 4697 init1: 4370 opt: 4584 Z-score: 5454.7 bits: 1020.1 E(85289): 0
Smith-Waterman score: 4721; 92.7% identity (92.8% similar) in 809 aa overlap (1-779:1-781)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
670 680 690
pF1KE5 FKEIPVTVYKP------------------------------IIKKYTKIIDGVPVEITEK
:::::::::.: :::::::::::::::::::
NP_001 FKEIPVTVYRPTLTKVKIEGEPEFRLIKEGETITEVIHGEPIIKKYTKIIDGVPVEITEK
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE5 ETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRL
:::::::::::::::::::::::::::::::::::
NP_001 ETREERIITGPEIKYTRISTGGGETEETLKKLLQE-------------------------
730 740 750
760 770
pF1KE5 LQGDTPVRKLQANKKVQGSRRRLREGRSQ
::::::::::::::::::::::::::
NP_001 ---DTPVRKLQANKKVQGSRRRLREGRSQ
760 770 780
>>NP_001273594 (OMIM: 608777) periostin isoform 5 precur (809 aa)
initn: 4370 init1: 4370 opt: 4421 Z-score: 5260.4 bits: 984.2 E(85289): 0
Smith-Waterman score: 4968; 96.2% identity (96.3% similar) in 809 aa overlap (1-779:1-809)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
670 680 690
pF1KE5 FKEIPVTVYKP------------------------------IIKKYTKIIDGVPVEITEK
:::::::::.: :::::::::::::::::::
NP_001 FKEIPVTVYRPTLTKVKIEGEPEFRLIKEGETITEVIHGEPIIKKYTKIIDGVPVEITEK
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE5 ETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETREERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRL
730 740 750 760 770 780
760 770
pF1KE5 LQGDTPVRKLQANKKVQGSRRRLREGRSQ
:::::::::::::::::::::::::::::
NP_001 LQGDTPVRKLQANKKVQGSRRRLREGRSQ
790 800
>>NP_001273595 (OMIM: 608777) periostin isoform 6 precur (749 aa)
initn: 4364 init1: 4364 opt: 4403 Z-score: 5239.5 bits: 980.2 E(85289): 0
Smith-Waterman score: 4780; 96.0% identity (96.1% similar) in 779 aa overlap (1-779:1-749)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE5 FKEIPVTVYKPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLK
:::::::::.: :::::::::::::::::::
NP_001 FKEIPVTVYSP------------------------------EIKYTRISTGGGETEETLK
670 680 690
730 740 750 760 770
pF1KE5 KLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
700 710 720 730 740
>>NP_001317446 (OMIM: 608777) periostin isoform 8 precur (808 aa)
initn: 4674 init1: 4347 opt: 4391 Z-score: 5224.7 bits: 977.6 E(85289): 0
Smith-Waterman score: 4665; 89.7% identity (89.8% similar) in 836 aa overlap (1-779:1-808)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
pF1KE5 FKEIPVTVY---------------------------------------------------
:::::::::
NP_001 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI
670 680 690 700 710 720
670 680 690 700 710 720
pF1KE5 ------KPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
730 740 750 760 770 780
730 740 750 760 770
pF1KE5 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
:: ::::::::::::::::::::::::::
NP_001 QE----------------------------DTPVRKLQANKKVQGSRRRLREGRSQ
790 800
>>XP_016875845 (OMIM: 608777) PREDICTED: periostin isofo (812 aa)
initn: 4854 init1: 4347 opt: 4391 Z-score: 5224.7 bits: 977.6 E(85289): 0
Smith-Waterman score: 4744; 92.8% identity (93.0% similar) in 810 aa overlap (1-753:1-810)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
pF1KE5 FKEIPVTVY---------------------------------------------------
:::::::::
XP_016 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI
670 680 690 700 710 720
670 680 690 700 710 720
pF1KE5 ------KPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
730 740 750 760 770 780
730 740 750 760 770
pF1KE5 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
::::::::::::::::::::::::::::::
XP_016 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGAN
790 800 810
>>XP_016875844 (OMIM: 608777) PREDICTED: periostin isofo (817 aa)
initn: 4854 init1: 4347 opt: 4391 Z-score: 5224.6 bits: 977.6 E(85289): 0
Smith-Waterman score: 4744; 92.8% identity (93.0% similar) in 810 aa overlap (1-753:1-810)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
pF1KE5 FKEIPVTVY---------------------------------------------------
:::::::::
XP_016 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI
670 680 690 700 710 720
670 680 690 700 710 720
pF1KE5 ------KPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
730 740 750 760 770 780
730 740 750 760 770
pF1KE5 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
::::::::::::::::::::::::::::::
XP_016 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGAIIAKYF
790 800 810
>>NP_006466 (OMIM: 608777) periostin isoform 1 precursor (836 aa)
initn: 5022 init1: 4347 opt: 4391 Z-score: 5224.5 bits: 977.6 E(85289): 0
Smith-Waterman score: 4752; 92.8% identity (93.0% similar) in 811 aa overlap (1-754:1-811)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
pF1KE5 FKEIPVTVY---------------------------------------------------
:::::::::
NP_006 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEGPTLTKVKIEGEPEFRLIKEGETI
670 680 690 700 710 720
670 680 690 700 710 720
pF1KE5 ------KPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TEVIHGEPIIKKYTKIIDGVPVEITEKETREERIITGPEIKYTRISTGGGETEETLKKLL
730 740 750 760 770 780
730 740 750 760 770
pF1KE5 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
:::::::::::::::::::::::::::::::
NP_006 QEEVTKVTKFIEGGDGHLFEDEEIKRLLQGDTPVRKLQANKKVQGSRRRLREGRSQ
790 800 810 820 830
>>XP_005266289 (OMIM: 608777) PREDICTED: periostin isofo (806 aa)
initn: 4347 init1: 4347 opt: 4390 Z-score: 5223.5 bits: 977.4 E(85289): 0
Smith-Waterman score: 4972; 96.5% identity (96.7% similar) in 806 aa overlap (1-779:1-806)
10 20 30 40 50 60
pF1KE5 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDHVYGTLGIVGATTTQRYSDAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLREEIEGKGSFTYFAPSNEAWDNLDSDIRRGLESNVNVELLNALHSHMINKRMLTKDLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NGMIIPSMYNNLGLFINHYPNGVVTVNCARIIHGNQIATNGVVHVIDRVLTQIGTSIQDF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEAEDDLSSFRAAAITSDILEALGRDGHFTLFAPTNEAFEKLPRGVLERIMGDKVASEAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKYHILNTLQCSESIMGGAVFETLEGNTIEIGCDGDSITVNGIKMVNKKDIVTNNGVIHL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDQVLIPDSAKQVIELAGKQQTTFTDLVAQLGLASALRPDGEYTLLAPVNNAFSDDTLSM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQRLLKLILQNHILKVKVGLNELYNGQILETIGGKQLRVFVYRTAVCIENSCMEKGSKQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNGAIHIFREIIKPAEKSLHEKLKQDKRFSTFLSLLEAADLKELLTQPGDWTLFVPTNDA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKGMTSEEKEILIRDKNALQNIILYHLTPGVFIGKGFEPGVTNILKTTQGSKIFLKEVND
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLLVNELKSKESDIMTTNGVIHVVDKLLYPADTPVGNDQLLEILNKLIKYIQIKFVRGST
610 620 630 640 650 660
670 680 690
pF1KE5 FKEIPVTVY---------------------------KPIIKKYTKIIDGVPVEITEKETR
::::::::: .:::::::::::::::::::::::
XP_005 FKEIPVTVYTTKIITKVVEPKIKVIEGSLQPIIKTEEPIIKKYTKIIDGVPVEITEKETR
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE5 EERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERIITGPEIKYTRISTGGGETEETLKKLLQEEVTKVTKFIEGGDGHLFEDEEIKRLLQG
730 740 750 760 770 780
760 770
pF1KE5 DTPVRKLQANKKVQGSRRRLREGRSQ
::::::::::::::::::::::::::
XP_005 DTPVRKLQANKKVQGSRRRLREGRSQ
790 800
779 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:23:08 2016 done: Tue Nov 8 06:23:10 2016
Total Scan time: 9.630 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]