Result of FASTA (omim) for
pFN21AE5721
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5721, 690 aa
1>>>pF1KE5721 690 - 690 aa - 690 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4273+/-0.00052; mu= 0.7167+/- 0.033
mean_var=256.4049+/-51.886, 0's: 0 Z-trim(116.0): 93 B-trim: 1135 in 1/53
Lambda= 0.080096
statistics sampled from 26838 (26931) to 26838 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.316), width: 16
Scan time: 10.040
The best scores are: opt bits E(85289)
XP_011511925 (OMIM: 123825,268000,613756) PREDICTE ( 690) 4507 535.0 3.7e-151
NP_000078 (OMIM: 123825,268000,613756) cGMP-gated ( 690) 4507 535.0 3.7e-151
XP_016863201 (OMIM: 123825,268000,613756) PREDICTE ( 690) 4507 535.0 3.7e-151
NP_001136036 (OMIM: 123825,268000,613756) cGMP-gat ( 759) 4507 535.0 4e-151
XP_005248106 (OMIM: 123825,268000,613756) PREDICTE ( 765) 4507 535.0 4e-151
NP_001289 (OMIM: 216900,600053) cyclic nucleotide- ( 694) 2759 333.0 2.4e-90
XP_011508856 (OMIM: 216900,600053) PREDICTED: cycl ( 749) 2759 333.0 2.5e-90
XP_006712306 (OMIM: 216900,600053) PREDICTED: cycl ( 731) 2750 331.9 5.1e-90
NP_001073347 (OMIM: 216900,600053) cyclic nucleoti ( 676) 2745 331.3 7.2e-90
NP_005131 (OMIM: 300338) cyclic nucleotide-gated o ( 664) 2609 315.6 3.8e-85
NP_001032406 (OMIM: 609472) cyclic nucleotide-gate ( 575) 1976 242.4 3.6e-63
XP_016872706 (OMIM: 609472) PREDICTED: cyclic nucl ( 577) 1962 240.8 1.1e-62
XP_016872707 (OMIM: 609472) PREDICTED: cyclic nucl ( 537) 1880 231.3 7.4e-60
XP_016872708 (OMIM: 609472) PREDICTED: cyclic nucl ( 537) 1880 231.3 7.4e-60
XP_011521172 (OMIM: 600724,613767) PREDICTED: cycl ( 868) 922 120.8 2.2e-26
NP_001273059 (OMIM: 600724,613767) cyclic nucleoti (1245) 922 120.9 2.9e-26
NP_001288 (OMIM: 600724,613767) cyclic nucleotide- (1251) 922 120.9 3e-26
NP_061971 (OMIM: 248200,262300,605080) cyclic nucl ( 809) 913 119.7 4.4e-26
XP_011515440 (OMIM: 248200,262300,605080) PREDICTE ( 671) 909 119.2 5.2e-26
NP_066550 (OMIM: 602780,615871) potassium/sodium h ( 890) 555 78.4 1.3e-13
NP_005468 (OMIM: 163800,605206,613123) potassium/s (1203) 546 77.4 3.4e-13
XP_011519450 (OMIM: 163800,605206,613123) PREDICTE ( 797) 520 74.3 2e-12
XP_011508118 (OMIM: 609973) PREDICTED: potassium/s ( 727) 519 74.1 2e-12
NP_065948 (OMIM: 609973) potassium/sodium hyperpol ( 774) 519 74.2 2.1e-12
NP_001185 (OMIM: 602781) potassium/sodium hyperpol ( 889) 511 73.3 4.5e-12
XP_011508120 (OMIM: 609973) PREDICTED: potassium/s ( 535) 493 71.0 1.3e-11
XP_016857407 (OMIM: 609973) PREDICTED: potassium/s ( 535) 493 71.0 1.3e-11
XP_011523615 (OMIM: 608168) PREDICTED: potassium v ( 711) 438 64.8 1.3e-09
XP_011523614 (OMIM: 608168) PREDICTED: potassium v ( 726) 438 64.8 1.3e-09
XP_011523613 (OMIM: 608168) PREDICTED: potassium v ( 726) 438 64.8 1.3e-09
NP_001265849 (OMIM: 608168) potassium voltage-gate ( 835) 438 64.8 1.5e-09
XP_016860709 (OMIM: 608169) PREDICTED: potassium v (1189) 441 65.3 1.5e-09
NP_150375 (OMIM: 608169) potassium voltage-gated c (1196) 441 65.3 1.5e-09
XP_016880669 (OMIM: 608168) PREDICTED: potassium v ( 871) 438 64.8 1.5e-09
XP_011510411 (OMIM: 608169) PREDICTED: potassium v (1204) 441 65.3 1.6e-09
XP_011523611 (OMIM: 608168) PREDICTED: potassium v ( 915) 438 64.9 1.6e-09
XP_011523610 (OMIM: 608168) PREDICTED: potassium v ( 918) 438 64.9 1.6e-09
XP_016880667 (OMIM: 608168) PREDICTED: potassium v ( 947) 438 64.9 1.6e-09
NP_001265848 (OMIM: 608168) potassium voltage-gate ( 958) 438 64.9 1.7e-09
XP_016880666 (OMIM: 608168) PREDICTED: potassium v ( 958) 438 64.9 1.7e-09
XP_016880665 (OMIM: 608168) PREDICTED: potassium v ( 983) 438 64.9 1.7e-09
XP_016880664 (OMIM: 608168) PREDICTED: potassium v ( 994) 438 64.9 1.7e-09
NP_110406 (OMIM: 608168) potassium voltage-gated c ( 994) 438 64.9 1.7e-09
XP_011508119 (OMIM: 609973) PREDICTED: potassium/s ( 720) 417 62.4 7.2e-09
NP_742054 (OMIM: 152427,609620,613688) potassium v ( 819) 417 62.4 7.9e-09
XP_011514488 (OMIM: 152427,609620,613688) PREDICTE ( 910) 417 62.4 8.6e-09
XP_011514487 (OMIM: 152427,609620,613688) PREDICTE (1059) 417 62.5 9.6e-09
XP_016867685 (OMIM: 152427,609620,613688) PREDICTE (1100) 417 62.5 9.9e-09
XP_016867684 (OMIM: 152427,609620,613688) PREDICTE (1109) 417 62.5 1e-08
NP_000229 (OMIM: 152427,609620,613688) potassium v (1159) 417 62.5 1e-08
>>XP_011511925 (OMIM: 123825,268000,613756) PREDICTED: c (690 aa)
initn: 4507 init1: 4507 opt: 4507 Z-score: 2834.7 bits: 535.0 E(85289): 3.7e-151
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 690 aa overlap (1-690:1-690)
10 20 30 40 50 60
pF1KE5 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 TTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 MHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 ADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 QILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLT
610 620 630 640 650 660
670 680 690
pF1KE5 KVEKFLKPLIDTEFSSIEGPGAESGPIDST
::::::::::::::::::::::::::::::
XP_011 KVEKFLKPLIDTEFSSIEGPGAESGPIDST
670 680 690
>>NP_000078 (OMIM: 123825,268000,613756) cGMP-gated cati (690 aa)
initn: 4507 init1: 4507 opt: 4507 Z-score: 2834.7 bits: 535.0 E(85289): 3.7e-151
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 690 aa overlap (1-690:1-690)
10 20 30 40 50 60
pF1KE5 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 TTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 MHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 ADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 QILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLT
610 620 630 640 650 660
670 680 690
pF1KE5 KVEKFLKPLIDTEFSSIEGPGAESGPIDST
::::::::::::::::::::::::::::::
NP_000 KVEKFLKPLIDTEFSSIEGPGAESGPIDST
670 680 690
>>XP_016863201 (OMIM: 123825,268000,613756) PREDICTED: c (690 aa)
initn: 4507 init1: 4507 opt: 4507 Z-score: 2834.7 bits: 535.0 E(85289): 3.7e-151
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 690 aa overlap (1-690:1-690)
10 20 30 40 50 60
pF1KE5 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 TTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 MHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 ADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 GSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE5 QILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLT
610 620 630 640 650 660
670 680 690
pF1KE5 KVEKFLKPLIDTEFSSIEGPGAESGPIDST
::::::::::::::::::::::::::::::
XP_016 KVEKFLKPLIDTEFSSIEGPGAESGPIDST
670 680 690
>>NP_001136036 (OMIM: 123825,268000,613756) cGMP-gated c (759 aa)
initn: 4507 init1: 4507 opt: 4507 Z-score: 2834.1 bits: 535.0 E(85289): 4e-151
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 690 aa overlap (1-690:70-759)
10 20 30
pF1KE5 MKLSMKNNIINTQQSFVTMPNVIVPDIEKE
::::::::::::::::::::::::::::::
NP_001 GFHHVGQAGLELLISSDLPTSASQSAGITDMKLSMKNNIINTQQSFVTMPNVIVPDIEKE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 IRRMENGACSSFSEDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRRMENGACSSFSEDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALF
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE5 NVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEE
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE5 EKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIV
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE5 YLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEI
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE5 RLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGND
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE5 TWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFA
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE5 TIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDE
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE5 KEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKG
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE5 DIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGY
580 590 600 610 620 630
580 590 600 610 620 630
pF1KE5 SDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRM
640 650 660 670 680 690
640 650 660 670 680 690
pF1KE5 EGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
700 710 720 730 740 750
>>XP_005248106 (OMIM: 123825,268000,613756) PREDICTED: c (765 aa)
initn: 4507 init1: 4507 opt: 4507 Z-score: 2834.1 bits: 535.0 E(85289): 4e-151
Smith-Waterman score: 4507; 100.0% identity (100.0% similar) in 690 aa overlap (1-690:76-765)
10 20 30
pF1KE5 MKLSMKNNIINTQQSFVTMPNVIVPDIEKE
::::::::::::::::::::::::::::::
XP_005 LARLLEPRTRETQTRLIEQQRLSERGARQDMKLSMKNNIINTQQSFVTMPNVIVPDIEKE
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE5 IRRMENGACSSFSEDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRRMENGACSSFSEDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALF
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE5 NVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEE
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE5 EKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIV
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE5 YLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEI
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE5 RLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGND
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE5 TWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFA
410 420 430 440 450 460
400 410 420 430 440 450
pF1KE5 TIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDE
470 480 490 500 510 520
460 470 480 490 500 510
pF1KE5 KEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKG
530 540 550 560 570 580
520 530 540 550 560 570
pF1KE5 DIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGY
590 600 610 620 630 640
580 590 600 610 620 630
pF1KE5 SDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRM
650 660 670 680 690 700
640 650 660 670 680 690
pF1KE5 EGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
710 720 730 740 750 760
>>NP_001289 (OMIM: 216900,600053) cyclic nucleotide-gate (694 aa)
initn: 2803 init1: 2748 opt: 2759 Z-score: 1743.0 bits: 333.0 E(85289): 2.4e-90
Smith-Waterman score: 2806; 62.3% identity (84.5% similar) in 684 aa overlap (10-681:4-684)
10 20 30 40 50
pF1KE5 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSE-----ES
:::: : . .. : .... : ::: . : .....:. . :.
NP_001 MAKINTQYSHPSRTHLKVKTSDRDLNRAENGLSRAHSSSEETSSVLQPGIAMET
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 ENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSN-KDQEPEE-KKKKKKEKK
.. ..:::. ... . .: .: : .:..... :. :.. . . :: .
NP_001 RGLADSGQGSFTGQGIAR---LSRLIFLLRRWAARHVHHQDQGPDSFPDRFRGAELKEVS
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 SKSDDKNENKNDPEKKKKKKD-----KEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNW
:. .. . : .. : . .. : . . ......:. .::...:.:::.: :: :
NP_001 SQESNAQANVGSQEPADRGRSAWPLAKCNTNTSNNTEEEKKTKKKDAIVVDPSSNLYYRW
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE5 LFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGL
: :.:::.::: ..: :::::::::.:: ::.::: .:..:..:..::.:::.:::::
NP_001 LTAIALPVFYNWYLLICRACFDELQSEYLMLWLVLDYSADVLYVLDVLVRARTGFLEQGL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 LVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRT
.:.. .: ..::.. :::::::::.:::: :.:.: ::::.:.::::.:::.::::.::
NP_001 MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYLKVGTNYPEVRFNRLLKFSRLFEFFDRT
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE5 ETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARK
::::::::.:::.:::.::.::::::::....::: ::::.:.::::.:. :: :::.::
NP_001 ETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRK
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE5 YVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARA
:.::::::::::::::::::::.: ::.:::::::.:::::::::::.:::::::::.::
NP_001 YIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRA
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE5 EFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAIN
::::.::.:::::.::.:.::.: :::.::::::.:::::::::::: :::::.::::::
NP_001 EFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAIN
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE5 VHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVA
:::::::::::: ::::::::::::::.: :.:::::::::::::.:::::.::::::::
NP_001 VHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVA
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE5 DDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEY
::::::::::::::::::::::::::::.::::::::.::::::::::::::::::::::
NP_001 DDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEY
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE5 PDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEY
:.:: :::::.::::::.:.: ..: ::.::::::::: .. .:.: :::::::.::::
NP_001 PEAKKALEEKGRQILMKDNLIDEELARAGADPKDLEEKVEQLGSSLDTLQTRFARLLAEY
600 610 620 630 640 650
650 660 670 680 690
pF1KE5 ESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
.. :.:.::::...:. .: : ... : ::
NP_001 NATQMKMKQRLSQLESQVKGGGDKPLADGEVPGDATKTEDKQQ
660 670 680 690
>>XP_011508856 (OMIM: 216900,600053) PREDICTED: cyclic n (749 aa)
initn: 2803 init1: 2748 opt: 2759 Z-score: 1742.6 bits: 333.0 E(85289): 2.5e-90
Smith-Waterman score: 2768; 66.9% identity (86.9% similar) in 617 aa overlap (75-681:123-739)
50 60 70 80 90 100
pF1KE5 DDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPE-
::. : . : . . . . ..:: :.
XP_011 RPLIGWTQWCAEDGGDESEMALAGSPGCSSGPQGRLSRLIFLLRRWAARHVHHQDQGPDS
100 110 120 130 140 150
110 120 130 140 150
pF1KE5 --EKKKKKKEKKSKSDDKNENKN----DPEKKKKKKDKEKKKKEEKSKDKKEEEK---KE
.. . . :. .:...: . : .: . .. : . . :.. .::.: :.
XP_011 FPDRFRGAELKEVSSQESNAQANVGSQEPADRGRSAWPLAKCNTNTSNNTEEEKKTKKKD
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE5 VVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLID
..:.:::.: :: :: :.:::.::: ..: :::::::::.:: ::.::: .:..:..:
XP_011 AIVVDPSSNLYYRWLTAIALPVFYNWYLLICRACFDELQSEYLMLWLVLDYSADVLYVLD
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE5 MFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNR
..::.:::.:::::.:.. .: ..::.. :::::::::.:::: :.:.: ::::.:.::
XP_011 VLVRARTGFLEQGLMVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYLKVGTNYPEVRFNR
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE5 LLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVY
::.:::.::::.::::::::::.:::.:::.::.::::::::....::: ::::.:.:::
XP_011 LLKFSRLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVY
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE5 PDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVG
:.:. :: :::.:::.::::::::::::::::::::.: ::.:::::::.::::::::::
XP_011 PNISIPEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVG
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE5 NIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVL
:.:::::::::.::::::.::.:::::.::.:.::.: :::.::::::.:::::::::::
XP_011 NVGSMISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVL
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE5 KYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGR
: :::::.:::::::::::::::::: ::::::::::::::.: :.:::::::::::::.
XP_011 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE5 EMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLF
:::::.::::::::::::::::::::::::::::::::::::.::::::::.::::::::
XP_011 EMYIINEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLF
580 590 600 610 620 630
580 590 600 610 620 630
pF1KE5 CLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSV
:::::::::::::::.:: :::::.::::::.:.: ..: ::.::::::::: .. .:.
XP_011 CLSKDDLMEALTEYPEAKKALEEKGRQILMKDNLIDEELARAGADPKDLEEKVEQLGSSL
640 650 660 670 680 690
640 650 660 670 680 690
pF1KE5 DLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
: :::::::.::::.. :.:.::::...:. .: : ... : ::
XP_011 DTLQTRFARLLAEYNATQMKMKQRLSQLESQVKGGGDKPLADGEVPGDATKTEDKQQ
700 710 720 730 740
>>XP_006712306 (OMIM: 216900,600053) PREDICTED: cyclic n (731 aa)
initn: 2800 init1: 2745 opt: 2750 Z-score: 1737.1 bits: 331.9 E(85289): 5.1e-90
Smith-Waterman score: 2761; 67.4% identity (86.7% similar) in 610 aa overlap (75-681:123-721)
50 60 70 80 90 100
pF1KE5 DDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPE-
::. : . : . . . . ..:: :.
XP_006 RPLIGWTQWCAEDGGDESEMALAGSPGCSSGPQGRLSRLIFLLRRWAARHVHHQDQGPDS
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE5 --EKKKKKKEKKSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPS
.. . . :. .:...: . : .. . ..:: : ::...:.:::
XP_006 FPDRFRGAELKEVSSQESNAQANVGSQEPADRGRRKKTK-----------KKDAIVVDPS
160 170 180 190 200
170 180 190 200 210 220
pF1KE5 GNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRT
.: :: :: :.:::.::: ..: :::::::::.:: ::.::: .:..:..:..::.::
XP_006 SNLYYRWLTAIALPVFYNWYLLICRACFDELQSEYLMLWLVLDYSADVLYVLDVLVRART
210 220 230 240 250 260
230 240 250 260 270 280
pF1KE5 GYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRM
:.:::::.:.. .: ..::.. :::::::::.:::: :.:.: ::::.:.::::.:::.
XP_006 GFLEQGLMVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYLKVGTNYPEVRFNRLLKFSRL
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE5 FEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPE
::::.::::::::::.:::.:::.::.::::::::....::: ::::.:.::::.:. ::
XP_006 FEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPE
330 340 350 360 370 380
350 360 370 380 390 400
pF1KE5 FGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMIS
:::.:::.::::::::::::::::::::.: ::.:::::::.:::::::::::.:::::
XP_006 HGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMIS
390 400 410 420 430 440
410 420 430 440 450 460
pF1KE5 NMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKL
::::.::::::.::.:::::.::.:.::.: :::.::::::.:::::::::::: :::::
XP_006 NMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKL
450 460 470 480 490 500
470 480 490 500 510 520
pF1KE5 RAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKE
.:::::::::::::::::: ::::::::::::::.: :.:::::::::::::.:::::.:
XP_006 KAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINE
510 520 530 540 550 560
530 540 550 560 570 580
pF1KE5 GKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDL
:::::::::::::::::::::::::::::::::::.::::::::.:::::::::::::::
XP_006 GKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDL
570 580 590 600 610 620
590 600 610 620 630 640
pF1KE5 MEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRF
::::::::.:: :::::.::::::.:.: ..: ::.::::::::: .. .:.: :::::
XP_006 MEALTEYPEAKKALEEKGRQILMKDNLIDEELARAGADPKDLEEKVEQLGSSLDTLQTRF
630 640 650 660 670 680
650 660 670 680 690
pF1KE5 ARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
::.::::.. :.:.::::...:. .: : ... : ::
XP_006 ARLLAEYNATQMKMKQRLSQLESQVKGGGDKPLADGEVPGDATKTEDKQQ
690 700 710 720 730
>>NP_001073347 (OMIM: 216900,600053) cyclic nucleotide-g (676 aa)
initn: 2800 init1: 2745 opt: 2745 Z-score: 1734.4 bits: 331.3 E(85289): 7.2e-90
Smith-Waterman score: 2798; 62.8% identity (83.5% similar) in 680 aa overlap (10-681:4-666)
10 20 30 40 50
pF1KE5 MKLSMKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSE-----ES
:::: : . .. : .... : ::: . : .....:. . :.
NP_001 MAKINTQYSHPSRTHLKVKTSDRDLNRAENGLSRAHSSSEETSSVLQPGIAMET
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 ENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPE---EKKKKKKEK
.. ..:::. ... . .: .: : .:.. .:: :. .. . . :
NP_001 RGLADSGQGSFTGQGIAR---LSRLIFLLRRWAARHVHH---QDQGPDSFPDRFRGAELK
60 70 80 90 100
120 130 140 150 160 170
pF1KE5 KSKSDDKNENKNDPEKKKKKKDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCI
. .:...: . : .. . ..:: : ::...:.:::.: :: :: :
NP_001 EVSSQESNAQANVGSQEPADRGRRKKTK-----------KKDAIVVDPSSNLYYRWLTAI
110 120 130 140 150
180 190 200 210 220 230
pF1KE5 TLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKE
.:::.::: ..: :::::::::.:: ::.::: .:..:..:..::.:::.:::::.:..
NP_001 ALPVFYNWYLLICRACFDELQSEYLMLWLVLDYSADVLYVLDVLVRARTGFLEQGLMVSD
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE5 ELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRT
.: ..::.. :::::::::.:::: :.:.: ::::.:.::::.:::.::::.::::::
NP_001 TNRLWQHYKTTTQFKLDVLSLVPTDLAYLKVGTNYPEVRFNRLLKFSRLFEFFDRTETRT
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE5 NYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYS
::::.:::.:::.::.::::::::....::: ::::.:.::::.:. :: :::.:::.::
NP_001 NYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIYS
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE5 LYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQA
::::::::::::::::::.: ::.:::::::.:::::::::::.:::::::::.::::::
NP_001 LYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQA
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE5 RIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLD
.::.:::::.::.:.::.: :::.::::::.:::::::::::: :::::.::::::::::
NP_001 KIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLD
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE5 TLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGV
:::::::: ::::::::::::::.: :.:::::::::::::.:::::.::::::::::::
NP_001 TLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGV
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE5 TQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAK
::::::::::::::::::::::::.::::::::.:::::::::::::::::::::::.::
NP_001 TQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAK
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE5 TMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQ
:::::.::::::.:.: ..: ::.::::::::: .. .:.: :::::::.::::.. :
NP_001 KALEEKGRQILMKDNLIDEELARAGADPKDLEEKVEQLGSSLDTLQTRFARLLAEYNATQ
580 590 600 610 620 630
660 670 680 690
pF1KE5 QKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST
.:.::::...:. .: : ... : ::
NP_001 MKMKQRLSQLESQVKGGGDKPLADGEVPGDATKTEDKQQ
640 650 660 670
>>NP_005131 (OMIM: 300338) cyclic nucleotide-gated olfac (664 aa)
initn: 2618 init1: 2461 opt: 2609 Z-score: 1649.6 bits: 315.6 E(85289): 3.8e-85
Smith-Waterman score: 2609; 67.2% identity (85.9% similar) in 574 aa overlap (103-676:78-650)
80 90 100 110 120 130
pF1KE5 KGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKK
: .:. .:.. . :. : :: .
NP_005 SELQRLADVDAPQQGRSGFRRIVRLVGIIREWANKNFREEEPRPDSFLERFRGPELQTVT
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE5 KDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDEL
.. : .. ..:: ..: :. :.::.:. :: ::: :..::.::: ...:::::..:
NP_005 TQEGDGKGDKDGEDKGTKKKFELFVLDPAGDWYYCWLFVIAMPVLYNWCLLVARACFSDL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE5 QSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLS
:. : ::.::::::.::. :.:.: :::.::::::::. :: ..: .::::::: :
NP_005 QKGYYLVWLVLDYVSDVVYIADLFIRLRTGFLEQGLLVKDTKKLRDNYIHTLQFKLDVAS
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE5 LIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIH
.:::::.:: . . ::.:.::::.:.::::::.::::::::::::::::::.::..:::
NP_005 IIPTDLIYFAVDIHSPEVRFNRLLHFARMFEFFDRTETRTNYPNIFRISNLVLYILVIIH
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE5 WNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRD
::::..:.:::.:::: ::::::.:.:::.: :::.:.: ::::::::::::::::::.:
NP_005 WNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKD
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE5 SEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEK
::.::. :::::::::::::::.:::::::::.::::::.:::.:.::.::.::: ::
NP_005 EEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKGMEA
350 360 370 380 390 400
440 450 460 470 480 490
pF1KE5 RVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELV
.::.::::::::::::::.:.:: :: ::::::::::::.:::::::: :::::::::::
NP_005 KVIRWFDYLWTNKKTVDEREILKNLPAKLRAEIAINVHLSTLKKVRIFHDCEAGLLVELV
410 420 430 440 450 460
500 510 520 530 540 550
pF1KE5 LKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNI
:::.:::.:::::::.:::::.::::::::::::::::::::...:: :: :::::::::
NP_005 LKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNI
470 480 490 500 510 520
560 570 580 590 600 610
pF1KE5 KGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLN
:::: ::::::::.:.::::::::::::::::.::::::: .:::.:..::::.:::: :
NP_005 KGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLLDEN
530 540 550 560 570 580
620 630 640 650 660 670
pF1KE5 IANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDT
: : :..::. ..: ... : :::.:.:::: . :::::::.: .: .: .
NP_005 -EVATSMEVDVQEKLGQLETNMETLYTRFGRLLAEYTGAQQKLKQRITVLETKMKQNNED
590 600 610 620 630 640
680 690
pF1KE5 EFSSIEGPGAESGPIDST
.. :
NP_005 DYLSDGMNSPELAAADEP
650 660
690 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:04:26 2016 done: Tue Nov 8 06:04:28 2016
Total Scan time: 10.040 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]