Result of FASTA (omim) for
pFN21AE5675
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5675, 558 aa
1>>>pF1KE5675 558 - 558 aa - 558 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5173+/-0.000419; mu= 15.3624+/- 0.026
mean_var=163.6379+/-34.983, 0's: 0 Z-trim(116.6): 91 B-trim: 1375 in 2/56
Lambda= 0.100261
statistics sampled from 27717 (27820) to 27717 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.326), width: 16
Scan time: 9.050
The best scores are: opt bits E(85289)
NP_001231827 (OMIM: 607527) polypyrimidine tract-b ( 558) 3650 540.5 5.3e-153
XP_011517567 (OMIM: 607527) PREDICTED: polypyrimid ( 561) 3634 538.2 2.7e-152
NP_005147 (OMIM: 607527) polypyrimidine tract-bind ( 552) 3523 522.1 1.8e-147
NP_001157262 (OMIM: 607527) polypyrimidine tract-b ( 555) 3507 519.8 8.9e-147
XP_006717409 (OMIM: 607527) PREDICTED: polypyrimid ( 521) 3410 505.7 1.4e-142
NP_001157260 (OMIM: 607527) polypyrimidine tract-b ( 524) 3394 503.4 7.2e-142
NP_001231826 (OMIM: 607527) polypyrimidine tract-b ( 547) 3128 465.0 2.8e-130
NP_001231825 (OMIM: 607527) polypyrimidine tract-b ( 457) 2976 442.9 1e-123
XP_016870854 (OMIM: 607527) PREDICTED: polypyrimid ( 452) 2952 439.4 1.1e-122
NP_002810 (OMIM: 600693) polypyrimidine tract-bind ( 557) 2736 408.3 3.3e-113
XP_005259654 (OMIM: 600693) PREDICTED: polypyrimid ( 559) 2736 408.3 3.3e-113
NP_114367 (OMIM: 600693) polypyrimidine tract-bind ( 550) 2681 400.3 8.2e-111
NP_114368 (OMIM: 600693) polypyrimidine tract-bind ( 531) 1203 186.5 1.8e-46
XP_005259655 (OMIM: 600693) PREDICTED: polypyrimid ( 533) 1203 186.5 1.8e-46
NP_001287914 (OMIM: 608449) polypyrimidine tract-b ( 537) 1154 179.4 2.5e-44
XP_011540178 (OMIM: 608449) PREDICTED: polypyrimid ( 545) 1154 179.4 2.5e-44
XP_016857440 (OMIM: 608449) PREDICTED: polypyrimid ( 548) 1154 179.4 2.5e-44
NP_001287916 (OMIM: 608449) polypyrimidine tract-b ( 548) 1154 179.4 2.5e-44
NP_001287919 (OMIM: 608449) polypyrimidine tract-b ( 480) 1142 177.6 7.7e-44
NP_001287918 (OMIM: 608449) polypyrimidine tract-b ( 532) 1142 177.7 8.3e-44
NP_001287915 (OMIM: 608449) polypyrimidine tract-b ( 540) 1142 177.7 8.4e-44
NP_001287917 (OMIM: 608449) polypyrimidine tract-b ( 536) 1139 177.2 1.1e-43
XP_011540176 (OMIM: 608449) PREDICTED: polypyrimid ( 544) 1139 177.3 1.1e-43
NP_067013 (OMIM: 608449) polypyrimidine tract-bind ( 531) 1127 175.5 3.7e-43
XP_011540177 (OMIM: 608449) PREDICTED: polypyrimid ( 539) 1127 175.5 3.8e-43
XP_011525190 (OMIM: 603083) PREDICTED: heterogeneo ( 528) 275 52.3 4.6e-06
XP_011531467 (OMIM: 611208) PREDICTED: heterogeneo ( 571) 270 51.6 8.1e-06
NP_001136122 (OMIM: 611208) heterogeneous nuclear ( 537) 258 49.8 2.6e-05
NP_612403 (OMIM: 611208) heterogeneous nuclear rib ( 542) 258 49.8 2.6e-05
XP_011531468 (OMIM: 611208) PREDICTED: heterogeneo ( 570) 258 49.8 2.7e-05
XP_005264697 (OMIM: 611208) PREDICTED: heterogeneo ( 590) 258 49.9 2.7e-05
XP_005264696 (OMIM: 611208) PREDICTED: heterogeneo ( 595) 258 49.9 2.8e-05
NP_001005335 (OMIM: 603083) heterogeneous nuclear ( 456) 247 48.1 7e-05
XP_011525191 (OMIM: 603083) PREDICTED: heterogeneo ( 456) 247 48.1 7e-05
XP_011525188 (OMIM: 603083) PREDICTED: heterogeneo ( 518) 247 48.2 7.6e-05
XP_011525189 (OMIM: 603083) PREDICTED: heterogeneo ( 532) 247 48.2 7.7e-05
NP_001524 (OMIM: 603083) heterogeneous nuclear rib ( 589) 247 48.3 8.3e-05
XP_011537999 (OMIM: 613171,613172) PREDICTED: RNA- (1099) 220 44.7 0.0019
XP_016871593 (OMIM: 613171,613172) PREDICTED: RNA- (1099) 220 44.7 0.0019
XP_016871592 (OMIM: 613171,613172) PREDICTED: RNA- (1172) 220 44.7 0.0019
NP_001127835 (OMIM: 613171,613172) RNA-binding pro (1227) 220 44.7 0.002
>>NP_001231827 (OMIM: 607527) polypyrimidine tract-bindi (558 aa)
initn: 3650 init1: 3650 opt: 3650 Z-score: 2867.8 bits: 540.5 E(85289): 5.3e-153
Smith-Waterman score: 3650; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558)
10 20 30 40 50 60
pF1KE5 MDASPSPFSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDASPSPFSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 CSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 AKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 FGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 PGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 ATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHN
490 500 510 520 530 540
550
pF1KE5 HDLGENHHLRVSFSKSTI
::::::::::::::::::
NP_001 HDLGENHHLRVSFSKSTI
550
>>XP_011517567 (OMIM: 607527) PREDICTED: polypyrimidine (561 aa)
initn: 3365 init1: 3365 opt: 3634 Z-score: 2855.3 bits: 538.2 E(85289): 2.7e-152
Smith-Waterman score: 3634; 99.5% identity (99.5% similar) in 561 aa overlap (1-558:1-561)
10 20 30 40 50
pF1KE5 MDASPSPFSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPST---ANGNDSKKFKRD
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 MDASPSPFSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPSTGVYANGNDSKKFKRD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 NYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 GTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 AHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 AAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGA
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 SGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 MNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE5 PPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIE
490 500 510 520 530 540
540 550
pF1KE5 LHNHDLGENHHLRVSFSKSTI
:::::::::::::::::::::
XP_011 LHNHDLGENHHLRVSFSKSTI
550 560
>>NP_005147 (OMIM: 607527) polypyrimidine tract-binding (552 aa)
initn: 3523 init1: 3523 opt: 3523 Z-score: 2768.6 bits: 522.1 E(85289): 1.8e-147
Smith-Waterman score: 3523; 99.8% identity (100.0% similar) in 539 aa overlap (20-558:14-552)
10 20 30 40 50 60
pF1KE5 MDASPSPFSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPP
.::::::::::::::::::::::::::::::::::::::::
NP_005 MDGVVTDLITVGLKRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPP
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 CSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 TPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 LPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 AKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 FGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 PGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNH
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE5 LSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE5 ATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHN
480 490 500 510 520 530
550
pF1KE5 HDLGENHHLRVSFSKSTI
::::::::::::::::::
NP_005 HDLGENHHLRVSFSKSTI
540 550
>>NP_001157262 (OMIM: 607527) polypyrimidine tract-bindi (555 aa)
initn: 3365 init1: 3365 opt: 3507 Z-score: 2756.1 bits: 519.8 E(85289): 8.9e-147
Smith-Waterman score: 3507; 99.3% identity (99.4% similar) in 542 aa overlap (20-558:14-555)
10 20 30 40 50
pF1KE5 MDASPSPFSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPST---ANGNDSKKFKRD
.::::::::::::::::::::::::: ::::::::::::
NP_001 MDGVVTDLITVGLKRGSDELLSSGIINGPFTMNSSTPSTGVYANGNDSKKFKRD
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 RPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 NYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 GTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 AHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 AAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 SGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 MNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE5 PPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIE
480 490 500 510 520 530
540 550
pF1KE5 LHNHDLGENHHLRVSFSKSTI
:::::::::::::::::::::
NP_001 LHNHDLGENHHLRVSFSKSTI
540 550
>>XP_006717409 (OMIM: 607527) PREDICTED: polypyrimidine (521 aa)
initn: 3410 init1: 3410 opt: 3410 Z-score: 2680.6 bits: 505.7 E(85289): 1.4e-142
Smith-Waterman score: 3410; 100.0% identity (100.0% similar) in 521 aa overlap (38-558:1-521)
10 20 30 40 50 60
pF1KE5 FSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPPCSPSRVL
::::::::::::::::::::::::::::::
XP_006 MNSSTPSTANGNDSKKFKRDRPPCSPSRVL
10 20 30
70 80 90 100 110 120
pF1KE5 HLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 RSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 LRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 QNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGII
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 SSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLL
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE5 VTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLY
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE5 GKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSN
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE5 IPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENH
460 470 480 490 500 510
550
pF1KE5 HLRVSFSKSTI
:::::::::::
XP_006 HLRVSFSKSTI
520
>>NP_001157260 (OMIM: 607527) polypyrimidine tract-bindi (524 aa)
initn: 3365 init1: 3365 opt: 3394 Z-score: 2668.0 bits: 503.4 E(85289): 7.2e-142
Smith-Waterman score: 3394; 99.4% identity (99.4% similar) in 524 aa overlap (38-558:1-524)
10 20 30 40 50 60
pF1KE5 FSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPST---ANGNDSKKFKRDRPPCSPS
:::::::: :::::::::::::::::::
NP_001 MNSSTPSTGVYANGNDSKKFKRDRPPCSPS
10 20 30
70 80 90 100 110 120
pF1KE5 RVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPIT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 PHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 SPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 LDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAP
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 GIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE5 VLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE5 RLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLH
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE5 LSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLG
460 470 480 490 500 510
550
pF1KE5 ENHHLRVSFSKSTI
::::::::::::::
NP_001 ENHHLRVSFSKSTI
520
>>NP_001231826 (OMIM: 607527) polypyrimidine tract-bindi (547 aa)
initn: 3094 init1: 3094 opt: 3128 Z-score: 2459.9 bits: 465.0 E(85289): 2.8e-130
Smith-Waterman score: 3128; 93.5% identity (94.9% similar) in 525 aa overlap (38-556:1-518)
10 20 30 40 50 60
pF1KE5 FSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPST---ANGNDSKKFKRDRPPCSPS
:::::::: :::::::::::::::::::
NP_001 MNSSTPSTGVYANGNDSKKFKRDRPPCSPS
10 20 30
70 80 90 100 110 120
pF1KE5 RVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPIT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 PHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 SPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMA
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 LDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAP
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 GIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE5 VLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE5 RLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLH
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE5 LSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDL-
::::::::::::::::::::::::::::::: .: .: ..: : :. .
NP_001 LSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQ---GLA----NSWAQVILLLPPPHSAGIT
460 470 480 490 500
550
pF1KE5 GENHH--LRVSFSKSTI
: .:: : : :: :
NP_001 GMSHHAWLSVLFSVSVPSVSSAYMFSILSCSFSSVPTRYFWTKN
510 520 530 540
>>NP_001231825 (OMIM: 607527) polypyrimidine tract-bindi (457 aa)
initn: 2976 init1: 2976 opt: 2976 Z-score: 2342.0 bits: 442.9 E(85289): 1e-123
Smith-Waterman score: 2976; 100.0% identity (100.0% similar) in 456 aa overlap (103-558:2-457)
80 90 100 110 120 130
pF1KE5 PCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPV
::::::::::::::::::::::::::::::
NP_001 MAFLEMASEEAAVTMVNYYTPITPHLRSQPV
10 20 30
140 150 160 170 180 190
pF1KE5 YIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVLRIII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVLRIII
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE5 ENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE5 ACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYA
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE5 GAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLVTNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLVTNLN
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE5 PDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLR
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE5 ATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSV
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE5 TVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVS
400 410 420 430 440 450
pF1KE5 FSKSTI
::::::
NP_001 FSKSTI
>>XP_016870854 (OMIM: 607527) PREDICTED: polypyrimidine (452 aa)
initn: 2952 init1: 2952 opt: 2952 Z-score: 2323.3 bits: 439.4 E(85289): 1.1e-122
Smith-Waterman score: 2952; 100.0% identity (100.0% similar) in 452 aa overlap (107-558:1-452)
80 90 100 110 120 130
pF1KE5 TEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQY
::::::::::::::::::::::::::::::
XP_016 MASEEAAVTMVNYYTPITPHLRSQPVYIQY
10 20 30
140 150 160 170 180 190
pF1KE5 SNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVLRIIIENLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVLRIIIENLF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE5 YPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCT
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE5 LRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAG
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE5 FAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLVTNLNPDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLVTNLNPDLI
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE5 TPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLS
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE5 KHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDD
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE5 LKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKS
400 410 420 430 440 450
pF1KE5 TI
::
XP_016 TI
>>NP_002810 (OMIM: 600693) polypyrimidine tract-binding (557 aa)
initn: 2138 init1: 1096 opt: 2736 Z-score: 2153.3 bits: 408.3 E(85289): 3.3e-113
Smith-Waterman score: 2736; 76.7% identity (90.9% similar) in 550 aa overlap (17-558:10-557)
10 20 30 40 50
pF1KE5 MDASPSPFSLPKKLNELSARRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRD-RP
....::::::.:. . :::: :.:.. :.:::::::::: : :
NP_002 MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDSKKFKGDSRS
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 PCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNY
::::.:.::.: ::::.:.:::::::::::::::::::.:::.:: .:::: :::::
NP_002 AGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 YTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLAL--SGGPSNE
:: .:: ::.::.:::.:::.:::::. :::::::::::::..::::.::: :.. .
NP_002 YTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 GTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVN
: .. :::::::::.:::::::::.::::::::::::::::::::::::::::::::::.
NP_002 GMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 AHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPM
:..::..::::::::::::::::::::::::::::::::::.:: :::.::.::::. :
NP_002 AQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 AAAFGAPGIIS-SPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVT----GRM
::::::::::: :::::: :: :....:::.::::: : :::.::.: :.:.. ::.
NP_002 AAAFGAPGIISASPYAGA-GFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAGRI
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 AIPGASGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADAN
:::: .: :::::::.::::. .::..:::::::::::.::::.:::::::::::::.:
NP_002 AIPGLAGA-GNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGN
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 QAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKN
::::::.::.:..:.:: .: :::::: ::::::::::::::::..::::::::::::::
NP_002 QAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKN
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE5 FQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAI
::::::::::::::::::::. .::: :: : ::.::::::::::::::.::::::.
NP_002 FQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAV
480 490 500 510 520 530
540 550
pF1KE5 QALIELHNHDLGENHHLRVSFSKSTI
::::.:::::::::::::::::::::
NP_002 QALIDLHNHDLGENHHLRVSFSKSTI
540 550
558 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:44:53 2016 done: Tue Nov 8 05:44:54 2016
Total Scan time: 9.050 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]