Result of FASTA (omim) for
pFN21AE5666
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5666, 520 aa
1>>>pF1KE5666 520 - 520 aa - 520 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1897+/-0.000396; mu= 19.0053+/- 0.025
mean_var=73.0907+/-14.977, 0's: 0 Z-trim(112.2): 71 B-trim: 230 in 1/52
Lambda= 0.150018
statistics sampled from 20996 (21072) to 20996 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.247), width: 16
Scan time: 6.660
The best scores are: opt bits E(85289)
NP_000889 (OMIM: 309860) amine oxidase [flavin-con ( 520) 3498 766.8 0
XP_016885012 (OMIM: 309860) PREDICTED: amine oxida ( 504) 3390 743.4 3.5e-214
XP_016885013 (OMIM: 309860) PREDICTED: amine oxida ( 504) 3390 743.4 3.5e-214
XP_005272665 (OMIM: 309860) PREDICTED: amine oxida ( 504) 3390 743.4 3.5e-214
NP_000231 (OMIM: 300615,309850) amine oxidase [fla ( 527) 2630 579.0 1.2e-164
NP_001257387 (OMIM: 300615,309850) amine oxidase [ ( 394) 1996 441.7 1.9e-123
NP_690863 (OMIM: 609742) L-amino-acid oxidase isof ( 567) 396 95.5 4.5e-19
NP_001244947 (OMIM: 609742) L-amino-acid oxidase i ( 589) 396 95.5 4.7e-19
NP_758962 (OMIM: 609742) L-amino-acid oxidase isof ( 589) 396 95.5 4.7e-19
NP_001244946 (OMIM: 609742) L-amino-acid oxidase i ( 589) 396 95.5 4.7e-19
XP_005248985 (OMIM: 613081) PREDICTED: lysine-spec ( 678) 249 63.7 2e-09
XP_011512687 (OMIM: 613081) PREDICTED: lysine-spec ( 691) 249 63.7 2e-09
XP_016865934 (OMIM: 613081) PREDICTED: lysine-spec ( 700) 249 63.7 2e-09
XP_016865931 (OMIM: 613081) PREDICTED: lysine-spec ( 802) 249 63.8 2.2e-09
XP_005248982 (OMIM: 613081) PREDICTED: lysine-spec ( 823) 249 63.8 2.3e-09
XP_016865929 (OMIM: 613081) PREDICTED: lysine-spec ( 832) 249 63.8 2.3e-09
XP_016865932 (OMIM: 613081) PREDICTED: lysine-spec ( 832) 249 63.8 2.3e-09
NP_787034 (OMIM: 615854) spermine oxidase isoform ( 502) 211 55.4 4.6e-07
NP_787036 (OMIM: 615854) spermine oxidase isoform ( 532) 211 55.4 4.9e-07
XP_016856206 (OMIM: 609132,616728) PREDICTED: lysi ( 802) 197 52.5 5.5e-06
XP_016856205 (OMIM: 609132,616728) PREDICTED: lysi ( 822) 197 52.5 5.6e-06
XP_006710536 (OMIM: 609132,616728) PREDICTED: lysi ( 828) 197 52.5 5.6e-06
NP_055828 (OMIM: 609132,616728) lysine-specific hi ( 852) 197 52.6 5.7e-06
XP_006710535 (OMIM: 609132,616728) PREDICTED: lysi ( 858) 197 52.6 5.8e-06
XP_005245843 (OMIM: 609132,616728) PREDICTED: lysi ( 872) 197 52.6 5.8e-06
XP_006710537 (OMIM: 609132,616728) PREDICTED: lysi ( 878) 197 52.6 5.9e-06
NP_001009999 (OMIM: 609132,616728) lysine-specific ( 876) 192 51.5 1.2e-05
XP_011512688 (OMIM: 613081) PREDICTED: lysine-spec ( 690) 182 49.2 4.6e-05
XP_005248983 (OMIM: 613081) PREDICTED: lysine-spec ( 822) 182 49.3 5.3e-05
XP_016865930 (OMIM: 613081) PREDICTED: lysine-spec ( 831) 182 49.3 5.3e-05
NP_787035 (OMIM: 615854) spermine oxidase isoform ( 190) 164 44.9 0.00025
NP_787033 (OMIM: 615854) spermine oxidase isoform ( 555) 164 45.3 0.00058
NP_001257620 (OMIM: 615854) spermine oxidase isofo ( 585) 164 45.3 0.0006
XP_011527563 (OMIM: 615854) PREDICTED: spermine ox ( 585) 164 45.3 0.0006
NP_694587 (OMIM: 613081) lysine-specific histone d ( 590) 164 45.3 0.00061
XP_016865935 (OMIM: 613081) PREDICTED: lysine-spec ( 464) 157 43.7 0.0014
>>NP_000889 (OMIM: 309860) amine oxidase [flavin-contain (520 aa)
initn: 3498 init1: 3498 opt: 3498 Z-score: 4092.3 bits: 766.8 E(85289): 0
Smith-Waterman score: 3498; 99.6% identity (99.8% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDHVGGRTYTLRNQKVKYVDLGGSY
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
NP_000 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TMDDMGREIQSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
430 440 450 460 470 480
490 500 510 520
pF1KE5 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
::::::::::::::::::::::::::::::::::::::::
NP_000 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
490 500 510 520
>>XP_016885012 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 3390 init1: 3390 opt: 3390 Z-score: 3966.1 bits: 743.4 E(85289): 3.5e-214
Smith-Waterman score: 3390; 99.6% identity (99.8% similar) in 504 aa overlap (17-520:1-504)
10 20 30 40 50 60
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDHVGGRTYTLRNQKVKYVDLGGSY
:::::::::::::::::::::.::::::::::::::::::::::
XP_016 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
10 20 30 40
70 80 90 100 110 120
pF1KE5 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 TMDDMGREIQSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE5 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
410 420 430 440 450 460
490 500 510 520
pF1KE5 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
::::::::::::::::::::::::::::::::::::::::
XP_016 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
470 480 490 500
>>XP_016885013 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 3390 init1: 3390 opt: 3390 Z-score: 3966.1 bits: 743.4 E(85289): 3.5e-214
Smith-Waterman score: 3390; 99.6% identity (99.8% similar) in 504 aa overlap (17-520:1-504)
10 20 30 40 50 60
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDHVGGRTYTLRNQKVKYVDLGGSY
:::::::::::::::::::::.::::::::::::::::::::::
XP_016 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
10 20 30 40
70 80 90 100 110 120
pF1KE5 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 TMDDMGREIQSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE5 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
410 420 430 440 450 460
490 500 510 520
pF1KE5 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
::::::::::::::::::::::::::::::::::::::::
XP_016 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
470 480 490 500
>>XP_005272665 (OMIM: 309860) PREDICTED: amine oxidase [ (504 aa)
initn: 3390 init1: 3390 opt: 3390 Z-score: 3966.1 bits: 743.4 E(85289): 3.5e-214
Smith-Waterman score: 3390; 99.6% identity (99.8% similar) in 504 aa overlap (17-520:1-504)
10 20 30 40 50 60
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDHVGGRTYTLRNQKVKYVDLGGSY
:::::::::::::::::::::.::::::::::::::::::::::
XP_005 MAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
10 20 30 40
70 80 90 100 110 120
pF1KE5 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 TMDDMGREIQSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE5 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE5 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
410 420 430 440 450 460
490 500 510 520
pF1KE5 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
::::::::::::::::::::::::::::::::::::::::
XP_005 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
470 480 490 500
>>NP_000231 (OMIM: 300615,309850) amine oxidase [flavin- (527 aa)
initn: 2628 init1: 2593 opt: 2630 Z-score: 3076.9 bits: 579.0 E(85289): 1.2e-164
Smith-Waterman score: 2630; 72.8% identity (90.3% similar) in 514 aa overlap (6-519:15-526)
10 20 30 40 50
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDHVGGRTYTLRNQKV
::::.::::::..::::: . :..:.::::::.:::::::.::..:
NP_000 MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 KYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT
:::.::.::::::::::::.::::.:::::: :::...::::.::::: ::::::::.
NP_000 DYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 YLDHNNFWRTMDDMGREIQSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNL
:::.::.:::.:.::.:: .::::.: :..::.::::::.::.:::..:...: ::::.
NP_000 YLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 CVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKL
::.: :::::::::::::::::::::.:.::::::::::::::::::::::::::.:::
NP_000 NVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPL
..:: ..::. .:...:::::: :: ::::.:::::: :::: : :: :::.: :.:.
NP_000 NHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 GSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARK
:.::::..:::: ::.:::::: :::. :.::.. :::::::.:. ::::::::.:: .
NP_000 GAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 LARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYG
::.: :: : ::.:::::::::: :::.::::::::::::::::::::.::::::.::::
NP_000 LAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 RVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVD
::.:::: ::.::::::::.::::::::::::::::::.:...::. : .:: .:::: :
NP_000 RVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKD
430 440 450 460 470 480
480 490 500 510 520
pF1KE5 VPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
::: :: :: ::.:::: :::..::..: :.:::::. .: :: :
NP_000 VPAVEITHTFWERNLPSVSGLLKIIGFST--SVTALGFVLYKYKLLPRS
490 500 510 520
>>NP_001257387 (OMIM: 300615,309850) amine oxidase [flav (394 aa)
initn: 1994 init1: 1959 opt: 1996 Z-score: 2337.1 bits: 441.7 E(85289): 1.9e-123
Smith-Waterman score: 1996; 72.2% identity (88.9% similar) in 395 aa overlap (125-519:1-393)
100 110 120 130 140 150
pF1KE5 KSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIQSDAPWKAPLAEEWDNMTMKELLDK
::.:: .::::.: :..::.::::::.::
NP_001 MGKEIPTDAPWEAQHADKWDKMTMKELIDK
10 20 30
160 170 180 190 200 210
pF1KE5 LCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGS
.:::..:...: ::::. ::.: :::::::::::::::::::::.:.:::::::::::::
NP_001 ICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGS
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE5 GQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHF
:::::::::::::.:::..:: ..::. .:...:::::: :: ::::.:::::: ::::
NP_001 GQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHF
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE5 NPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPE
: :: :::.: :.:.:.::::..:::: ::.:::::: :::. :.::.. :::::::.
NP_001 RPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPD
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE5 GNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYS
:. ::::::::.:: .::.: :: : ::.:::::::::: :::.:::::::::::::::
NP_001 GSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYS
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE5 GGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAM
:::::.::::::.::::::.:::: ::.::::::::.::::::::::::::::::.:...
NP_001 GGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGL
280 290 300 310 320 330
460 470 480 490 500 510
pF1KE5 GKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKR
::. : .:: .:::: :::: :: :: ::.:::: :::..::..: :.:::::. .:
NP_001 GKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFST--SVTALGFVLYKY
340 350 360 370 380
520
pF1KE5 GLLVRV
:: :
NP_001 KLLPRS
390
>>NP_690863 (OMIM: 609742) L-amino-acid oxidase isoform (567 aa)
initn: 343 init1: 190 opt: 396 Z-score: 463.4 bits: 95.5 E(85289): 4.5e-19
Smith-Waterman score: 411; 24.4% identity (55.5% similar) in 488 aa overlap (7-475:62-527)
10 20 30
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR
:.:::.:..:..:::.: :.: .:..:::
NP_690 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 DHVGGRTYTLRNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHH
...::: .: :.:.. .. :.. :...::: .: . :::. : .. .. .:.
NP_690 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHE
100 110 120 130 140 150
100 110 120 130 140
pF1KE5 VKGKSY-----PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIQSDAPWKAPLAEEWDNM
:: ..: : . . . . .. . .... ..... . :: ....
NP_690 VKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERH
160 170 180 190 200
150 160 170 180 190 200
pF1KE5 TMKE-LLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGG
:. : :: . .. : :: ... .....: ... . . . ..
NP_690 TLLEYLLGEGNLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRL
210 220 230 240 250
210 220 230 240 250
pF1KE5 QERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKY
: ..::: . . ... :. : :. ::. . : ..: :. . : .. .:
NP_690 QYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADV
260 270 280 290 300 310
260 270 280 290 300 310
pF1KE5 VI-SAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIID
:. .: :.. .: :.:::: .. . :. . : .. ...::::.. : .
NP_690 VLLTASGPAVK-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--S
320 330 340 350 360 370
320 330 340 350 360 370
pF1KE5 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EA
. . : . . :: . .. . : .: :..:: :. . : . : . .
NP_690 NTDRPSRMIFYPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQ
380 390 400 410 420 430
380 390 400 410 420 430
pF1KE5 LEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYME
: : : :.:.: : ... ::.. : :::::: .:: . :..:
NP_690 LWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVE
440 450 460 470 480 490
440 450 460 470 480 490
pF1KE5 GAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIG
::... ::: .: : : .. . : .. :. .:
NP_690 TAVKSALRAAIKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHP
500 510 520 530 540
500 510 520
pF1KE5 LTTIFSATALGFLAHKRGLLVRV
NP_690 PVQGQLSLQNTTHTRTSH
550 560
>>NP_001244947 (OMIM: 609742) L-amino-acid oxidase isofo (589 aa)
initn: 343 init1: 190 opt: 396 Z-score: 463.1 bits: 95.5 E(85289): 4.7e-19
Smith-Waterman score: 411; 24.4% identity (55.5% similar) in 488 aa overlap (7-475:84-549)
10 20 30
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR
:.:::.:..:..:::.: :.: .:..:::
NP_001 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 DHVGGRTYTLRNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHH
...::: .: :.:.. .. :.. :...::: .: . :::. : .. .. .:.
NP_001 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHE
120 130 140 150 160 170
100 110 120 130 140
pF1KE5 VKGKSY-----PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIQSDAPWKAPLAEEWDNM
:: ..: : . . . . .. . .... ..... . :: ....
NP_001 VKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERH
180 190 200 210 220 230
150 160 170 180 190 200
pF1KE5 TMKE-LLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGG
:. : :: . .. : :: ... .....: ... . . . ..
NP_001 TLLEYLLGEGNLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRL
240 250 260 270
210 220 230 240 250
pF1KE5 QERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKY
: ..::: . . ... :. : :. ::. . : ..: :. . : .. .:
NP_001 QYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADV
280 290 300 310 320 330
260 270 280 290 300 310
pF1KE5 VI-SAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIID
:. .: :.. .: :.:::: .. . :. . : .. ...::::.. : .
NP_001 VLLTASGPAVK-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--S
340 350 360 370 380 390
320 330 340 350 360 370
pF1KE5 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EA
. . : . . :: . .. . : .: :..:: :. . : . : . .
NP_001 NTDRPSRMIFYPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQ
400 410 420 430 440 450
380 390 400 410 420 430
pF1KE5 LEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYME
: : : :.:.: : ... ::.. : :::::: .:: . :..:
NP_001 LWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVE
460 470 480 490 500 510
440 450 460 470 480 490
pF1KE5 GAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIG
::... ::: .: : : .. . : .. :. .:
NP_001 TAVKSALRAAIKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHP
520 530 540 550 560 570
500 510 520
pF1KE5 LTTIFSATALGFLAHKRGLLVRV
NP_001 PVQGQLSLQNTTHTRTSH
580
>>NP_758962 (OMIM: 609742) L-amino-acid oxidase isoform (589 aa)
initn: 343 init1: 190 opt: 396 Z-score: 463.1 bits: 95.5 E(85289): 4.7e-19
Smith-Waterman score: 411; 24.4% identity (55.5% similar) in 488 aa overlap (7-475:84-549)
10 20 30
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR
:.:::.:..:..:::.: :.: .:..:::
NP_758 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 DHVGGRTYTLRNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHH
...::: .: :.:.. .. :.. :...::: .: . :::. : .. .. .:.
NP_758 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHE
120 130 140 150 160 170
100 110 120 130 140
pF1KE5 VKGKSY-----PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIQSDAPWKAPLAEEWDNM
:: ..: : . . . . .. . .... ..... . :: ....
NP_758 VKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERH
180 190 200 210 220 230
150 160 170 180 190 200
pF1KE5 TMKE-LLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGG
:. : :: . .. : :: ... .....: ... . . . ..
NP_758 TLLEYLLGEGNLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRL
240 250 260 270
210 220 230 240 250
pF1KE5 QERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKY
: ..::: . . ... :. : :. ::. . : ..: :. . : .. .:
NP_758 QYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADV
280 290 300 310 320 330
260 270 280 290 300 310
pF1KE5 VI-SAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIID
:. .: :.. .: :.:::: .. . :. . : .. ...::::.. : .
NP_758 VLLTASGPAVK-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--S
340 350 360 370 380 390
320 330 340 350 360 370
pF1KE5 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EA
. . : . . :: . .. . : .: :..:: :. . : . : . .
NP_758 NTDRPSRMIFYPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQ
400 410 420 430 440 450
380 390 400 410 420 430
pF1KE5 LEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYME
: : : :.:.: : ... ::.. : :::::: .:: . :..:
NP_758 LWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVE
460 470 480 490 500 510
440 450 460 470 480 490
pF1KE5 GAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIG
::... ::: .: : : .. . : .. :. .:
NP_758 TAVKSALRAAIKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHP
520 530 540 550 560 570
500 510 520
pF1KE5 LTTIFSATALGFLAHKRGLLVRV
NP_758 PVQGQLSLQNTTHTRTSH
580
>>NP_001244946 (OMIM: 609742) L-amino-acid oxidase isofo (589 aa)
initn: 343 init1: 190 opt: 396 Z-score: 463.1 bits: 95.5 E(85289): 4.7e-19
Smith-Waterman score: 411; 24.4% identity (55.5% similar) in 488 aa overlap (7-475:84-549)
10 20 30
pF1KE5 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR
:.:::.:..:..:::.: :.: .:..:::
NP_001 PFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEAD
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 DHVGGRTYTLRNQKVKYVDLGGSYVGPTQNRIL-RLAKELGLETYKVNEVER----LIHH
...::: .: :.:.. .. :.. :...::: .: . :::. : .. .. .:.
NP_001 NRIGGRIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQGLGLNLTKFTQYDKNTWTEVHE
120 130 140 150 160 170
100 110 120 130 140
pF1KE5 VKGKSY-----PFRGPFPPVWNPITYLDHNNFWRTMDDMGREIQSDAPWKAPLAEEWDNM
:: ..: : . . . . .. . .... ..... . :: ....
NP_001 VKLRNYVVEKVPEKLGYALRPQEKGHSPEDIYQMALNQALKDLKALGCRKA--MKKFERH
180 190 200 210 220 230
150 160 170 180 190 200
pF1KE5 TMKE-LLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGG
:. : :: . .. : :: ... .....: ... . . . ..
NP_001 TLLEYLLGEGNLSRPAVQL---------LGDVMSEDGFFYLSFAEALRAHSCL---SDRL
240 250 260 270
210 220 230 240 250
pF1KE5 QERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVE------TLNHEMYEAKY
: ..::: . . ... :. : :. ::. . : ..: :. . : .. .:
NP_001 QYSRIVGGWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETSPPARNLKVLKADV
280 290 300 310 320 330
260 270 280 290 300 310
pF1KE5 VI-SAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIID
:. .: :.. .: :.:::: .. . :. . : .. ...::::.. : .
NP_001 VLLTASGPAVK-RITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGH--S
340 350 360 370 380 390
320 330 340 350 360 370
pF1KE5 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSL-EA
. . : . . :: . .. . : .: :..:: :. . : . : . .
NP_001 NTDRPSRMIFYPPPREGALL-LASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQ
400 410 420 430 440 450
380 390 400 410 420 430
pF1KE5 LEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYME
: : : :.:.: : ... ::.. : :::::: .:: . :..:
NP_001 LWDGTGVVKRWAEDQHSQGGFVVQ-PPALWQTEKDDWTVPYGRIYFAGEHTA-YPHGWVE
460 470 480 490 500 510
440 450 460 470 480 490
pF1KE5 GAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIG
::... ::: .: : : .. . : .. :. .:
NP_001 TAVKSALRAAIKINSRKG--PASDTASPEGHASDMEGQGHVHGVASSPSHDLAKEEGSHP
520 530 540 550 560 570
500 510 520
pF1KE5 LTTIFSATALGFLAHKRGLLVRV
NP_001 PVQGQLSLQNTTHTRTSH
580
520 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:41:05 2016 done: Tue Nov 8 05:41:06 2016
Total Scan time: 6.660 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]