Result of FASTA (omim) for
pFN21AE5653
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5653, 506 aa
1>>>pF1KE5653 506 - 506 aa - 506 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9650+/-0.000398; mu= 21.8260+/- 0.025
mean_var=101.4340+/-21.524, 0's: 0 Z-trim(113.1): 116 B-trim: 967 in 1/56
Lambda= 0.127345
statistics sampled from 22215 (22340) to 22215 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.262), width: 16
Scan time: 8.430
The best scores are: opt bits E(85289)
NP_061323 (OMIM: 615231) roquin-2 isoform 2 [Homo (1064) 2943 552.1 2.9e-156
NP_001094058 (OMIM: 615231) roquin-2 isoform 1 [Ho (1191) 2943 552.2 3.1e-156
XP_011507533 (OMIM: 609424) PREDICTED: roquin-1 is (1076) 2512 472.9 2e-132
XP_005244978 (OMIM: 609424) PREDICTED: roquin-1 is (1113) 2512 473.0 2e-132
NP_001287781 (OMIM: 609424) roquin-1 isoform d [Ho (1124) 2512 473.0 2e-132
NP_001287780 (OMIM: 609424) roquin-1 isoform c [Ho (1125) 2512 473.0 2e-132
NP_742068 (OMIM: 609424) roquin-1 isoform b [Homo (1133) 2512 473.0 2e-132
NP_001287779 (OMIM: 609424) roquin-1 isoform a [Ho (1134) 2512 473.0 2e-132
>>NP_061323 (OMIM: 615231) roquin-2 isoform 2 [Homo sapi (1064 aa)
initn: 2943 init1: 2943 opt: 2943 Z-score: 2926.5 bits: 552.1 E(85289): 2.9e-156
Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 QQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDREKIS
::::::::::::::::::::::
NP_061 QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI
430 440 450 460 470 480
>>NP_001094058 (OMIM: 615231) roquin-2 isoform 1 [Homo s (1191 aa)
initn: 2943 init1: 2943 opt: 2943 Z-score: 2926.0 bits: 552.2 E(85289): 3.1e-156
Smith-Waterman score: 2943; 100.0% identity (100.0% similar) in 442 aa overlap (1-442:1-442)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 QQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDREKIS
::::::::::::::::::::::
NP_001 QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI
430 440 450 460 470 480
>>XP_011507533 (OMIM: 609424) PREDICTED: roquin-1 isofor (1076 aa)
initn: 2393 init1: 1915 opt: 2512 Z-score: 2498.5 bits: 472.9 E(85289): 2e-132
Smith-Waterman score: 2512; 84.0% identity (94.8% similar) in 445 aa overlap (1-442:1-445)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::: :::.::::::: . :::...:::::::.::::: :::::::::::::::.::::
XP_011 MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTD
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKL-SNLGENKHYEVAKKCVEDLALYLKPLSGGKGVA
:..:::: :::::::::::..: : : :.. ..:::: ::::::.:::::::::...::.
XP_011 IELLPVNSALLQLVGAQVPEQQPITLCSGVEDTKHYEEAKKCVEELALYLKPLSSARGVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 --SLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLS
: .::.:::::::::::::.:::::::::.::::::::::::::::::::::::::::
XP_011 LNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 ANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISP
::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::::::.:
XP_011 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 EQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELL
.::::::::: .:::::::::::::.: :::.:::::::.::::::::::::::::::::
XP_011 DQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 ANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCR
:::::.::: ::::::::..:::.::::::::.:::.:.:: . :: .::::: :::
XP_011 ANIDPSPDAPPPTWEQLENGLVAVRTVVHGLVDYIQNHSKKGADQQQPPQHSKYKTYMCR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 DLRQQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDRE
:..:.::::::..::::::::::::
XP_011 DMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGLPSAAILPDE
430 440 450 460 470 480
>>XP_005244978 (OMIM: 609424) PREDICTED: roquin-1 isofor (1113 aa)
initn: 2393 init1: 1915 opt: 2512 Z-score: 2498.4 bits: 473.0 E(85289): 2e-132
Smith-Waterman score: 2512; 84.0% identity (94.8% similar) in 445 aa overlap (1-442:1-445)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::: :::.::::::: . :::...:::::::.::::: :::::::::::::::.::::
XP_005 MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTD
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKL-SNLGENKHYEVAKKCVEDLALYLKPLSGGKGVA
:..:::: :::::::::::..: : : :.. ..:::: ::::::.:::::::::...::.
XP_005 IELLPVNSALLQLVGAQVPEQQPITLCSGVEDTKHYEEAKKCVEELALYLKPLSSARGVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 --SLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLS
: .::.:::::::::::::.:::::::::.::::::::::::::::::::::::::::
XP_005 LNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 ANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISP
::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::::::.:
XP_005 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 EQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELL
.::::::::: .:::::::::::::.: :::.:::::::.::::::::::::::::::::
XP_005 DQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 ANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCR
:::::.::: ::::::::..:::.::::::::.:::.:.:: . :: .::::: :::
XP_005 ANIDPSPDAPPPTWEQLENGLVAVRTVVHGLVDYIQNHSKKGADQQQPPQHSKYKTYMCR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 DLRQQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDRE
:..:.::::::..::::::::::::
XP_005 DMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGLPSAAILPDE
430 440 450 460 470 480
>>NP_001287781 (OMIM: 609424) roquin-1 isoform d [Homo s (1124 aa)
initn: 2393 init1: 1915 opt: 2512 Z-score: 2498.3 bits: 473.0 E(85289): 2e-132
Smith-Waterman score: 2512; 84.0% identity (94.8% similar) in 445 aa overlap (1-442:1-445)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::: :::.::::::: . :::...:::::::.::::: :::::::::::::::.::::
NP_001 MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTD
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKL-SNLGENKHYEVAKKCVEDLALYLKPLSGGKGVA
:..:::: :::::::::::..: : : :.. ..:::: ::::::.:::::::::...::.
NP_001 IELLPVNSALLQLVGAQVPEQQPITLCSGVEDTKHYEEAKKCVEELALYLKPLSSARGVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 --SLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLS
: .::.:::::::::::::.:::::::::.::::::::::::::::::::::::::::
NP_001 LNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 ANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISP
::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::::::.:
NP_001 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 EQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELL
.::::::::: .:::::::::::::.: :::.:::::::.::::::::::::::::::::
NP_001 DQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 ANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCR
:::::.::: ::::::::..:::.::::::::.:::.:.:: . :: .::::: :::
NP_001 ANIDPSPDAPPPTWEQLENGLVAVRTVVHGLVDYIQNHSKKGADQQQPPQHSKYKTYMCR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 DLRQQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDRE
:..:.::::::..::::::::::::
NP_001 DMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGLPSAAILPDE
430 440 450 460 470 480
>>NP_001287780 (OMIM: 609424) roquin-1 isoform c [Homo s (1125 aa)
initn: 2393 init1: 1915 opt: 2512 Z-score: 2498.3 bits: 473.0 E(85289): 2e-132
Smith-Waterman score: 2512; 84.0% identity (94.8% similar) in 445 aa overlap (1-442:1-445)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::: :::.::::::: . :::...:::::::.::::: :::::::::::::::.::::
NP_001 MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTD
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKL-SNLGENKHYEVAKKCVEDLALYLKPLSGGKGVA
:..:::: :::::::::::..: : : :.. ..:::: ::::::.:::::::::...::.
NP_001 IELLPVNSALLQLVGAQVPEQQPITLCSGVEDTKHYEEAKKCVEELALYLKPLSSARGVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 --SLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLS
: .::.:::::::::::::.:::::::::.::::::::::::::::::::::::::::
NP_001 LNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 ANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISP
::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::::::.:
NP_001 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 EQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELL
.::::::::: .:::::::::::::.: :::.:::::::.::::::::::::::::::::
NP_001 DQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 ANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCR
:::::.::: ::::::::..:::.::::::::.:::.:.:: . :: .::::: :::
NP_001 ANIDPSPDAPPPTWEQLENGLVAVRTVVHGLVDYIQNHSKKGADQQQPPQHSKYKTYMCR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 DLRQQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDRE
:..:.::::::..::::::::::::
NP_001 DMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGLPSAAILPDE
430 440 450 460 470 480
>>NP_742068 (OMIM: 609424) roquin-1 isoform b [Homo sapi (1133 aa)
initn: 2393 init1: 1915 opt: 2512 Z-score: 2498.3 bits: 473.0 E(85289): 2e-132
Smith-Waterman score: 2512; 84.0% identity (94.8% similar) in 445 aa overlap (1-442:1-445)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::: :::.::::::: . :::...:::::::.::::: :::::::::::::::.::::
NP_742 MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTD
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKL-SNLGENKHYEVAKKCVEDLALYLKPLSGGKGVA
:..:::: :::::::::::..: : : :.. ..:::: ::::::.:::::::::...::.
NP_742 IELLPVNSALLQLVGAQVPEQQPITLCSGVEDTKHYEEAKKCVEELALYLKPLSSARGVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 --SLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLS
: .::.:::::::::::::.:::::::::.::::::::::::::::::::::::::::
NP_742 LNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 ANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 SNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISP
::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::::::.:
NP_742 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 EQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELL
.::::::::: .:::::::::::::.: :::.:::::::.::::::::::::::::::::
NP_742 DQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 ANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCR
:::::.::: ::::::::..:::.::::::::.:::.:.:: . :: .::::: :::
NP_742 ANIDPSPDAPPPTWEQLENGLVAVRTVVHGLVDYIQNHSKKGADQQQPPQHSKYKTYMCR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 DLRQQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDRE
:..:.::::::..::::::::::::
NP_742 DMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGLPSAAILPDE
430 440 450 460 470 480
>>NP_001287779 (OMIM: 609424) roquin-1 isoform a [Homo s (1134 aa)
initn: 2393 init1: 1915 opt: 2512 Z-score: 2498.3 bits: 473.0 E(85289): 2e-132
Smith-Waterman score: 2512; 84.0% identity (94.8% similar) in 445 aa overlap (1-442:1-445)
10 20 30 40 50 60
pF1KE5 MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
::::: :::.::::::: . :::...:::::::.::::: :::::::::::::::.::::
NP_001 MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTD
10 20 30 40 50 60
70 80 90 100 110
pF1KE5 IDVLPVNFALLQLVGAQVPDHQSIKL-SNLGENKHYEVAKKCVEDLALYLKPLSGGKGVA
:..:::: :::::::::::..: : : :.. ..:::: ::::::.:::::::::...::.
NP_001 IELLPVNSALLQLVGAQVPEQQPITLCSGVEDTKHYEEAKKCVEELALYLKPLSSARGVG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 --SLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLS
: .::.:::::::::::::.:::::::::.::::::::::::::::::::::::::::
NP_001 LNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 ANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISP
::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::::::.:
NP_001 SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 EQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELL
.::::::::: .:::::::::::::.: :::.:::::::.::::::::::::::::::::
NP_001 DQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 ANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCR
:::::.::: ::::::::..:::.::::::::.:::.:.:: . :: .::::: :::
NP_001 ANIDPSPDAPPPTWEQLENGLVAVRTVVHGLVDYIQNHSKKGADQQQPPQHSKYKTYMCR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 DLRQQGGCPRGTNCTFAHSQEELEKCNPRGLYLHCCLLSSVASLGTVHNELYKQQHCDRE
:..:.::::::..::::::::::::
NP_001 DMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGLPSAAILPDE
430 440 450 460 470 480
506 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:07:59 2016 done: Tue Nov 8 04:08:00 2016
Total Scan time: 8.430 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]