Result of FASTA (omim) for
pFN21AE5650
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5650, 498 aa
1>>>pF1KE5650 498 - 498 aa - 498 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4865+/-0.000356; mu= 12.7201+/- 0.022
mean_var=98.8354+/-19.519, 0's: 0 Z-trim(115.8): 48 B-trim: 10 in 1/53
Lambda= 0.129008
statistics sampled from 26474 (26522) to 26474 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.311), width: 16
Scan time: 8.570
The best scores are: opt bits E(85289)
NP_001287715 (OMIM: 153700,193220,607854,611809,61 ( 498) 3411 645.4 1.1e-184
XP_005274272 (OMIM: 153700,193220,607854,611809,61 ( 479) 1845 354.0 5.7e-97
NP_001287716 (OMIM: 153700,193220,607854,611809,61 ( 525) 1845 354.0 6.2e-97
NP_004174 (OMIM: 153700,193220,607854,611809,61319 ( 585) 1845 354.0 6.8e-97
XP_011543535 (OMIM: 153700,193220,607854,611809,61 ( 383) 1816 348.5 2e-95
XP_016873717 (OMIM: 153700,193220,607854,611809,61 ( 558) 1816 348.6 2.7e-95
NP_001132915 (OMIM: 153700,193220,607854,611809,61 ( 604) 1816 348.6 2.9e-95
XP_011543532 (OMIM: 153700,193220,607854,611809,61 ( 633) 1816 348.6 3e-95
XP_005274267 (OMIM: 153700,193220,607854,611809,61 ( 664) 1816 348.6 3.2e-95
XP_011543531 (OMIM: 153700,193220,607854,611809,61 ( 664) 1816 348.6 3.2e-95
XP_005274273 (OMIM: 153700,193220,607854,611809,61 ( 375) 1584 305.3 2e-82
XP_016873718 (OMIM: 153700,193220,607854,611809,61 ( 435) 1584 305.4 2.2e-82
XP_005274276 (OMIM: 153700,193220,607854,611809,61 ( 321) 1574 303.4 6.2e-82
XP_016873719 (OMIM: 153700,193220,607854,611809,61 ( 329) 1254 243.9 5.4e-64
XP_005274278 (OMIM: 153700,193220,607854,611809,61 ( 270) 1225 238.4 1.9e-62
NP_001269543 (OMIM: 607337) bestrophin-3 isoform 4 ( 398) 1109 216.9 8.4e-56
XP_006719319 (OMIM: 607337) PREDICTED: bestrophin- ( 410) 1109 216.9 8.7e-56
NP_116124 (OMIM: 607337) bestrophin-3 isoform 1 [H ( 668) 1109 217.0 1.3e-55
XP_005260020 (OMIM: 607335) PREDICTED: bestrophin- ( 509) 1060 207.9 5.8e-53
NP_060152 (OMIM: 607335) bestrophin-2 [Homo sapien ( 509) 1060 207.9 5.8e-53
NP_001269542 (OMIM: 607337) bestrophin-3 isoform 3 ( 562) 838 166.6 1.7e-40
XP_011536263 (OMIM: 607337) PREDICTED: bestrophin- ( 562) 838 166.6 1.7e-40
XP_016856512 (OMIM: 607336) PREDICTED: bestrophin- ( 473) 825 164.1 8e-40
NP_695006 (OMIM: 607336) bestrophin-4 [Homo sapien ( 473) 825 164.1 8e-40
XP_016856511 (OMIM: 607336) PREDICTED: bestrophin- ( 473) 825 164.1 8e-40
XP_016856510 (OMIM: 607336) PREDICTED: bestrophin- ( 475) 825 164.1 8e-40
XP_016856509 (OMIM: 607336) PREDICTED: bestrophin- ( 475) 825 164.1 8e-40
XP_011536265 (OMIM: 607337) PREDICTED: bestrophin- ( 506) 590 120.4 1.2e-26
XP_011536264 (OMIM: 607337) PREDICTED: bestrophin- ( 506) 590 120.4 1.2e-26
XP_016874354 (OMIM: 607337) PREDICTED: bestrophin- ( 178) 503 103.9 3.9e-22
NP_689652 (OMIM: 607337) bestrophin-3 isoform 2 [H ( 455) 303 66.9 1.4e-10
NP_001269544 (OMIM: 607337) bestrophin-3 isoform 5 ( 72) 232 53.3 2.8e-07
NP_001269545 (OMIM: 607337) bestrophin-3 isoform 5 ( 72) 232 53.3 2.8e-07
XP_011536267 (OMIM: 607337) PREDICTED: bestrophin- ( 344) 181 44.2 0.00074
>>NP_001287715 (OMIM: 153700,193220,607854,611809,613194 (498 aa)
initn: 3411 init1: 3411 opt: 3411 Z-score: 3436.8 bits: 645.4 E(85289): 1.1e-184
Smith-Waterman score: 3411; 100.0% identity (100.0% similar) in 498 aa overlap (1-498:1-498)
10 20 30 40 50 60
pF1KE5 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVSLLAVDEMHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVSLLAVDEMHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 DLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 GIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 GAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTL
430 440 450 460 470 480
490
pF1KE5 KDHMDPYWALENRDEAHS
::::::::::::::::::
NP_001 KDHMDPYWALENRDEAHS
490
>>XP_005274272 (OMIM: 153700,193220,607854,611809,613194 (479 aa)
initn: 1844 init1: 1844 opt: 1845 Z-score: 1861.9 bits: 354.0 E(85289): 5.7e-97
Smith-Waterman score: 3017; 94.4% identity (94.4% similar) in 479 aa overlap (47-498:1-479)
20 30 40 50 60 70
pF1KE5 PISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGN
::::::::::::::::::::::::::::::
XP_005 MSLVSGFVEGKDEQGRLLRRTLIRYANLGN
10 20 30
80 90 100 110 120 130
pF1KE5 VLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 LGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQ
100 110 120 130 140 150
200 210 220 230
pF1KE5 FLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKV--------------------------
::::::::::::::::::::::::::::::::::
XP_005 FLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQ
160 170 180 190 200 210
240 250 260 270 280
pF1KE5 -SLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQ
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE5 PNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNV
280 290 300 310 320 330
350 360 370 380 390 400
pF1KE5 RGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGID
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE5 TKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPL
400 410 420 430 440 450
470 480 490
pF1KE5 EQSPTNIHTTLKDHMDPYWALENRDEAHS
:::::::::::::::::::::::::::::
XP_005 EQSPTNIHTTLKDHMDPYWALENRDEAHS
460 470
>>NP_001287716 (OMIM: 153700,193220,607854,611809,613194 (525 aa)
initn: 1844 init1: 1844 opt: 1845 Z-score: 1861.3 bits: 354.0 E(85289): 6.2e-97
Smith-Waterman score: 3347; 94.9% identity (94.9% similar) in 525 aa overlap (1-498:1-525)
10 20 30 40 50 60
pF1KE5 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKV----------
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE
190 200 210 220 230 240
240 250 260 270
pF1KE5 -----------------SLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM
:::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE5 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN
430 440 450 460 470 480
460 470 480 490
pF1KE5 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAHS
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAHS
490 500 510 520
>>NP_004174 (OMIM: 153700,193220,607854,611809,613194) b (585 aa)
initn: 1844 init1: 1844 opt: 1845 Z-score: 1860.6 bits: 354.0 E(85289): 6.8e-97
Smith-Waterman score: 3347; 94.9% identity (94.9% similar) in 525 aa overlap (1-498:61-585)
10 20 30
pF1KE5 MFEKLTLYCDSYIQLIPISFVLGFYVTLVV
::::::::::::::::::::::::::::::
NP_004 LLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVTLVV
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 TRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE5 FPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSL
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE5 LNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELD
220 230 240 250 260 270
220 230 240
pF1KE5 LVVPVFTFLQFFFYVGWLKV---------------------------SLLAVDEMHQDLP
:::::::::::::::::::: :::::::::::::
NP_004 LVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLP
280 290 300 310 320 330
250 260 270 280 290 300
pF1KE5 RMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGII
340 350 360 370 380 390
310 320 330 340 350 360
pF1KE5 GRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAV
400 410 420 430 440 450
370 380 390 400 410 420
pF1KE5 DAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAK
460 470 480 490 500 510
430 440 450 460 470 480
pF1KE5 KSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDH
520 530 540 550 560 570
490
pF1KE5 MDPYWALENRDEAHS
:::::::::::::::
NP_004 MDPYWALENRDEAHS
580
>>XP_011543535 (OMIM: 153700,193220,607854,611809,613194 (383 aa)
initn: 1810 init1: 1810 opt: 1816 Z-score: 1834.2 bits: 348.5 E(85289): 2e-95
Smith-Waterman score: 1816; 95.7% identity (97.1% similar) in 280 aa overlap (223-497:24-303)
200 210 220 230 240
pF1KE5 VGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGW-----LKVSLLAVDEMHQDLPRMEP
: ..: :.::::::::::::::::::
XP_011 MNKIMQLQVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEP
10 20 30 40 50
250 260 270 280 290 300
pF1KE5 DMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFL
60 70 80 90 100 110
310 320 330 340 350 360
pF1KE5 GLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFK
120 130 140 150 160 170
370 380 390 400 410 420
pF1KE5 SAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFE
180 190 200 210 220 230
430 440 450 460 470 480
pF1KE5 LLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPY
240 250 260 270 280 290
490
pF1KE5 WALENRDEAHS
::::::. :
XP_011 WALENRSVLHLNQGHCIALCPTPASLALSLPFLHNFLGFHHCQSTLDLRPALAWGIYLAT
300 310 320 330 340 350
>>XP_016873717 (OMIM: 153700,193220,607854,611809,613194 (558 aa)
initn: 1810 init1: 1810 opt: 1816 Z-score: 1831.7 bits: 348.6 E(85289): 2.7e-95
Smith-Waterman score: 2988; 93.7% identity (93.9% similar) in 478 aa overlap (47-497:1-478)
20 30 40 50 60 70
pF1KE5 PISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGN
::::::::::::::::::::::::::::::
XP_016 MSLVSGFVEGKDEQGRLLRRTLIRYANLGN
10 20 30
80 90 100 110 120 130
pF1KE5 VLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAW
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 LGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQ
100 110 120 130 140 150
200 210 220 230
pF1KE5 FLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKV--------------------------
::::::::::::::::::::::::::::::::::
XP_016 FLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQ
160 170 180 190 200 210
240 250 260 270 280
pF1KE5 -SLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQ
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE5 PNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNV
280 290 300 310 320 330
350 360 370 380 390 400
pF1KE5 RGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGID
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE5 TKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPL
400 410 420 430 440 450
470 480 490
pF1KE5 EQSPTNIHTTLKDHMDPYWALENRDEAHS
::::::::::::::::::::::::. :
XP_016 EQSPTNIHTTLKDHMDPYWALENRSVLHLNQGHCIALCPTPASLALSLPFLHNFLGFHHC
460 470 480 490 500 510
>>NP_001132915 (OMIM: 153700,193220,607854,611809,613194 (604 aa)
initn: 1810 init1: 1810 opt: 1816 Z-score: 1831.2 bits: 348.6 E(85289): 2.9e-95
Smith-Waterman score: 3318; 94.3% identity (94.5% similar) in 524 aa overlap (1-497:1-524)
10 20 30 40 50 60
pF1KE5 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVV
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKV----------
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGE
190 200 210 220 230 240
240 250 260 270
pF1KE5 -----------------SLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM
:::::::::::::::::::::::::::::::::::::::::::
NP_001 DDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTFNISLNKEEMEFQPNQEDEEDAHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFP
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE5 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEPSAPSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEHPEVSQVRRKTVEFN
430 440 450 460 470 480
460 470 480 490
pF1KE5 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRDEAHS
::::::::::::::::::::::::::::::::::::::::. :
NP_001 LTDMPEIPENHLKEPLEQSPTNIHTTLKDHMDPYWALENRSVLHLNQGHCIALCPTPASL
490 500 510 520 530 540
NP_001 ALSLPFLHNFLGFHHCQSTLDLRPALAWGIYLATFTGILGKCSGPFLTSPWYHPEDFLGP
550 560 570 580 590 600
>>XP_011543532 (OMIM: 153700,193220,607854,611809,613194 (633 aa)
initn: 1810 init1: 1810 opt: 1816 Z-score: 1830.9 bits: 348.6 E(85289): 3e-95
Smith-Waterman score: 3318; 94.3% identity (94.5% similar) in 524 aa overlap (1-497:30-553)
10 20 30
pF1KE5 MFEKLTLYCDSYIQLIPISFVLGFYVTLVVT
:::::::::::::::::::::::::::::::
XP_011 MQAPSFGPPFNPKRDHYPSRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVTLVVT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 RWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKRF
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 PSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 NEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELDL
190 200 210 220 230 240
220 230 240
pF1KE5 VVPVFTFLQFFFYVGWLKV---------------------------SLLAVDEMHQDLPR
::::::::::::::::::: ::::::::::::::
XP_011 VVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPR
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE5 MEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGIIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGIIG
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE5 RFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAVD
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE5 AFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAKK
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE5 SFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDHM
490 500 510 520 530 540
490
pF1KE5 DPYWALENRDEAHS
:::::::::. :
XP_011 DPYWALENRSVLHLNQGHCIALCPTPASLALSLPFLHNFLGFHHCQSTLDLRPALAWGIY
550 560 570 580 590 600
>>XP_005274267 (OMIM: 153700,193220,607854,611809,613194 (664 aa)
initn: 1810 init1: 1810 opt: 1816 Z-score: 1830.6 bits: 348.6 E(85289): 3.2e-95
Smith-Waterman score: 3318; 94.3% identity (94.5% similar) in 524 aa overlap (1-497:61-584)
10 20 30
pF1KE5 MFEKLTLYCDSYIQLIPISFVLGFYVTLVV
::::::::::::::::::::::::::::::
XP_005 LLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVTLVV
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 TRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE5 FPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSL
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE5 LNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELD
220 230 240 250 260 270
220 230 240
pF1KE5 LVVPVFTFLQFFFYVGWLKV---------------------------SLLAVDEMHQDLP
:::::::::::::::::::: :::::::::::::
XP_005 LVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLP
280 290 300 310 320 330
250 260 270 280 290 300
pF1KE5 RMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGII
340 350 360 370 380 390
310 320 330 340 350 360
pF1KE5 GRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAV
400 410 420 430 440 450
370 380 390 400 410 420
pF1KE5 DAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAK
460 470 480 490 500 510
430 440 450 460 470 480
pF1KE5 KSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDH
520 530 540 550 560 570
490
pF1KE5 MDPYWALENRDEAHS
::::::::::. :
XP_005 MDPYWALENRSVLHLNQGHCIALCPTPASLALSLPFLHNFLGFHHCQSTLDLRPALAWGI
580 590 600 610 620 630
>>XP_011543531 (OMIM: 153700,193220,607854,611809,613194 (664 aa)
initn: 1810 init1: 1810 opt: 1816 Z-score: 1830.6 bits: 348.6 E(85289): 3.2e-95
Smith-Waterman score: 3318; 94.3% identity (94.5% similar) in 524 aa overlap (1-497:61-584)
10 20 30
pF1KE5 MFEKLTLYCDSYIQLIPISFVLGFYVTLVV
::::::::::::::::::::::::::::::
XP_011 LLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVTLVV
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE5 TRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKR
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE5 FPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSL
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE5 LNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELD
220 230 240 250 260 270
220 230 240
pF1KE5 LVVPVFTFLQFFFYVGWLKV---------------------------SLLAVDEMHQDLP
:::::::::::::::::::: :::::::::::::
XP_011 LVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLP
280 290 300 310 320 330
250 260 270 280 290 300
pF1KE5 RMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPNQEDEEDAHAGII
340 350 360 370 380 390
310 320 330 340 350 360
pF1KE5 GRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAV
400 410 420 430 440 450
370 380 390 400 410 420
pF1KE5 DAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPSAPSKLHSVTGIDTKDKSLKTVSSGAK
460 470 480 490 500 510
430 440 450 460 470 480
pF1KE5 KSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSFELLSESDGALMEHPEVSQVRRKTVEFNLTDMPEIPENHLKEPLEQSPTNIHTTLKDH
520 530 540 550 560 570
490
pF1KE5 MDPYWALENRDEAHS
::::::::::. :
XP_011 MDPYWALENRSVLHLNQGHCIALCPTPASLALSLPFLHNFLGFHHCQSTLDLRPALAWGI
580 590 600 610 620 630
498 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:33:24 2016 done: Tue Nov 8 05:33:25 2016
Total Scan time: 8.570 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]