Result of FASTA (omim) for
pFN21AE5615
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5615, 571 aa
1>>>pF1KE5615 571 - 571 aa - 571 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8602+/-0.00039; mu= 21.3275+/- 0.024
mean_var=63.0344+/-12.715, 0's: 0 Z-trim(110.9): 102 B-trim: 106 in 1/50
Lambda= 0.161542
statistics sampled from 19234 (19340) to 19234 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.227), width: 16
Scan time: 7.990
The best scores are: opt bits E(85289)
NP_001122402 (OMIM: 607577) ectonucleoside triphos ( 608) 3607 849.8 0
NP_004892 (OMIM: 607577) ectonucleoside triphospha ( 616) 3581 843.7 0
NP_065087 (OMIM: 616753) ectonucleoside triphospha ( 604) 2315 548.7 2e-155
XP_016872453 (OMIM: 601752,615683) PREDICTED: ecto ( 276) 333 86.5 1.2e-16
XP_016872452 (OMIM: 601752,615683) PREDICTED: ecto ( 288) 333 86.5 1.3e-16
NP_001157651 (OMIM: 601752,615683) ectonucleoside ( 469) 333 86.7 1.8e-16
XP_016872447 (OMIM: 601752,615683) PREDICTED: ecto ( 470) 333 86.7 1.9e-16
NP_001307845 (OMIM: 601752,615683) ectonucleoside ( 482) 333 86.7 1.9e-16
NP_001767 (OMIM: 601752,615683) ectonucleoside tri ( 510) 333 86.7 2e-16
XP_011538673 (OMIM: 601752,615683) PREDICTED: ecto ( 517) 333 86.7 2e-16
NP_001091645 (OMIM: 601752,615683) ectonucleoside ( 517) 333 86.7 2e-16
NP_001157650 (OMIM: 601752,615683) ectonucleoside ( 522) 333 86.7 2e-16
XP_016872451 (OMIM: 601752,615683) PREDICTED: ecto ( 295) 321 83.7 8.9e-16
XP_011538678 (OMIM: 601752,615683) PREDICTED: ecto ( 430) 321 83.9 1.2e-15
XP_011538676 (OMIM: 601752,615683) PREDICTED: ecto ( 469) 321 83.9 1.3e-15
XP_011538675 (OMIM: 601752,615683) PREDICTED: ecto ( 481) 321 83.9 1.3e-15
XP_011538674 (OMIM: 601752,615683) PREDICTED: ecto ( 489) 321 83.9 1.3e-15
XP_011538672 (OMIM: 601752,615683) PREDICTED: ecto ( 529) 321 83.9 1.4e-15
NP_001237 (OMIM: 602012) ectonucleoside triphospha ( 472) 278 73.9 1.3e-12
NP_982293 (OMIM: 602012) ectonucleoside triphospha ( 495) 278 73.9 1.4e-12
XP_011532568 (OMIM: 603161) PREDICTED: ectonucleos ( 283) 267 71.1 5.3e-12
NP_001278890 (OMIM: 603161) ectonucleoside triphos ( 452) 267 71.3 7.7e-12
NP_001278889 (OMIM: 603161) ectonucleoside triphos ( 529) 267 71.3 8.7e-12
NP_001239 (OMIM: 603161) ectonucleoside triphospha ( 529) 267 71.3 8.7e-12
XP_016877306 (OMIM: 603162) PREDICTED: ectonucleos ( 360) 248 66.8 1.4e-10
XP_006720389 (OMIM: 603162) PREDICTED: ectonucleos ( 381) 248 66.8 1.4e-10
XP_016877305 (OMIM: 603162) PREDICTED: ectonucleos ( 381) 248 66.8 1.4e-10
NP_001308913 (OMIM: 603162) ectonucleoside triphos ( 405) 248 66.8 1.5e-10
XP_006720388 (OMIM: 603162) PREDICTED: ectonucleos ( 407) 248 66.8 1.5e-10
NP_001317118 (OMIM: 603162) ectonucleoside triphos ( 407) 248 66.8 1.5e-10
XP_016877303 (OMIM: 603162) PREDICTED: ectonucleos ( 407) 248 66.8 1.5e-10
NP_001308916 (OMIM: 603162) ectonucleoside triphos ( 428) 248 66.8 1.6e-10
XP_016877302 (OMIM: 603162) PREDICTED: ectonucleos ( 428) 248 66.8 1.6e-10
NP_001308915 (OMIM: 603162) ectonucleoside triphos ( 428) 248 66.8 1.6e-10
NP_001308917 (OMIM: 603162) ectonucleoside triphos ( 428) 248 66.8 1.6e-10
NP_001240 (OMIM: 603162) ectonucleoside triphospha ( 428) 248 66.8 1.6e-10
XP_005268281 (OMIM: 603162) PREDICTED: ectonucleos ( 428) 248 66.8 1.6e-10
NP_001308914 (OMIM: 603162) ectonucleoside triphos ( 428) 248 66.8 1.6e-10
XP_011517514 (OMIM: 602012) PREDICTED: ectonucleos ( 392) 238 64.5 7.4e-10
NP_940987 (OMIM: 616748) ectonucleoside triphospha ( 458) 237 64.3 9.9e-10
NP_001028285 (OMIM: 616748) ectonucleoside triphos ( 495) 237 64.3 1e-09
XP_011516968 (OMIM: 616748) PREDICTED: ectonucleos ( 566) 237 64.4 1.2e-09
XP_011516967 (OMIM: 616748) PREDICTED: ectonucleos ( 603) 237 64.4 1.2e-09
NP_001309315 (OMIM: 603160) ectonucleoside triphos ( 433) 221 60.5 1.3e-08
NP_001309317 (OMIM: 603160) ectonucleoside triphos ( 437) 221 60.6 1.3e-08
NP_001309318 (OMIM: 603160) ectonucleoside triphos ( 447) 221 60.6 1.3e-08
NP_001309320 (OMIM: 603160) ectonucleoside triphos ( 450) 221 60.6 1.3e-08
NP_001309319 (OMIM: 603160) ectonucleoside triphos ( 450) 221 60.6 1.3e-08
NP_001309321 (OMIM: 603160) ectonucleoside triphos ( 453) 221 60.6 1.3e-08
NP_001309322 (OMIM: 603160) ectonucleoside triphos ( 454) 221 60.6 1.3e-08
>>NP_001122402 (OMIM: 607577) ectonucleoside triphosphat (608 aa)
initn: 3607 init1: 3607 opt: 3607 Z-score: 4538.6 bits: 849.8 E(85289): 0
Smith-Waterman score: 3607; 99.8% identity (99.8% similar) in 535 aa overlap (1-535:1-535)
10 20 30 40 50 60
pF1KE5 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEVAKNLLAEFNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEVAKNLLAEFNLG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 CDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 YGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 QCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRKIGMLII
::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 QCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAF
490 500 510 520 530 540
550 560 570
pF1KE5 PCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
NP_001 RASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAALWMEEGLP
550 560 570 580 590 600
>>NP_004892 (OMIM: 607577) ectonucleoside triphosphate d (616 aa)
initn: 3593 init1: 1903 opt: 3581 Z-score: 4505.8 bits: 843.7 E(85289): 0
Smith-Waterman score: 3581; 98.3% identity (98.3% similar) in 543 aa overlap (1-535:1-543)
10 20 30 40 50 60
pF1KE5 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKT--------EEVAKN
:::::::::::::::::::::::::::::::::::::::::::::: ::::::
NP_004 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE5 IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE5 ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL
490 500 510 520 530 540
540 550 560 570
pF1KE5 RKIGMLIIPCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
: :
NP_004 RDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAA
550 560 570 580 590 600
>>NP_065087 (OMIM: 616753) ectonucleoside triphosphate d (604 aa)
initn: 2337 init1: 2172 opt: 2315 Z-score: 2911.3 bits: 548.7 E(85289): 2e-155
Smith-Waterman score: 2315; 62.0% identity (82.4% similar) in 545 aa overlap (1-535:1-530)
10 20 30 40 50
pF1KE5 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQ-IMVISVLAAAVSLLYFSVVIIRNKYG
:.::..: : ::::.:.. :. : ::: . .... . :: . .. .:. .
NP_065 MARISFSYLCPASWYFTV-PTVSPF-----LRQRVAFLGLFFISCLLLLMLIIDFRHWSA
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 RLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLD
: ::....:::::: ..:::::..::.:::.::::::::::.::: :::::::::::::
NP_065 SLPRDRQYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 IRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCT
:.::::.: .::: ::::::: .: .::..:::. :::.::: ::: ::::::::::::
NP_065 IKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 AGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEH
::::.::: .: ::: ::. :.:..::::::.:.::::::::::::::::::::::::.:
NP_065 AGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDH
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 IEDDD-EAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVP--------KTEEVA
...: ::. :. : :.::.:::::::.: ::::::: : ::.:
NP_065 EDESDAEATQEL---------AAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAA
240 250 260 270 280
300 310 320 330 340 350
pF1KE5 KNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGL
: :::::::::::..:::::::::.:::::::: ::::::: .. .:..::::::..:::
NP_065 KILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE5 TPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQ
.:: :.::::::. . : ...:.:....:: ::. : ..:.. ..: .:.::::.::
NP_065 SPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQ
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE5 PPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYA
:: :.::::::::::.::::::::.:: :.. :.:::.:::. ::.: .:: ::..
NP_065 SPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFS
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE5 SHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFL
:::: :::::::::::::..:.:.:: :: .: .:.:: :::.:::::::::::.::::
NP_065 SHADEHRLKYQCFKSAWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFL
470 480 490 500 510 520
540 550 560 570
pF1KE5 PLRKIGMLIIPCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
::: .
NP_065 PLRDLRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAP
530 540 550 560 570 580
>>XP_016872453 (OMIM: 601752,615683) PREDICTED: ectonucl (276 aa)
initn: 386 init1: 230 opt: 333 Z-score: 419.7 bits: 86.5 E(85289): 1.2e-16
Smith-Waterman score: 393; 34.5% identity (63.5% similar) in 249 aa overlap (86-325:46-261)
60 70 80 90 100 110
pF1KE5 NKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPH
::.::::.: ::: . ...: :: .. :
XP_016 NILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKEN--
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE5 DLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLY
: ..:... : ::::.:. . .... :.. .. : : .::..:.:::.:
XP_016 DTGVVHQVEECRVKG------PGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVY
80 90 100 110 120
180 190 200 210 220
pF1KE5 ILCTAGMRILP-ESQQKA-----ILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIG
. :::::.: ::.. : ..: :.. : ::: . :..:.:..::.:.::
XP_016 LGATAGMRLLRMESEELADRVLDVVERSLSNYP--FDF----QGARIITGQEEGAYGWIT
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE5 INFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEV
::..::.: .. . .: :... ..: : ::.::.:::... ::... .
XP_016 INYLLGKF------SQKTRWFSIVPYETNN----QETFGALDLGGASTQVTF-VPQNQTI
190 200 210 220 230
290 300 310 320 330 340
pF1KE5 AK--NLLAEFNL-GCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGK
. : : .: : : : : ::. .:: .: . :
XP_016 ESPDNAL-QFRLYGKD-------YNVYTHSFLCYGKDQALWQKLAKDIQMPSAF
240 250 260 270
350 360 370 380 390 400
pF1KE5 QTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLN
>>XP_016872452 (OMIM: 601752,615683) PREDICTED: ectonucl (288 aa)
initn: 383 init1: 230 opt: 333 Z-score: 419.5 bits: 86.5 E(85289): 1.3e-16
Smith-Waterman score: 393; 34.5% identity (63.5% similar) in 249 aa overlap (86-325:58-273)
60 70 80 90 100 110
pF1KE5 NKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPH
::.::::.: ::: . ...: :: .. :
XP_016 NILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKEN--
30 40 50 60 70 80
120 130 140 150 160 170
pF1KE5 DLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLY
: ..:... : ::::.:. . .... :.. .. : : .::..:.:::.:
XP_016 DTGVVHQVEECRVKG------PGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVY
90 100 110 120 130
180 190 200 210 220
pF1KE5 ILCTAGMRILP-ESQQKA-----ILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIG
. :::::.: ::.. : ..: :.. : ::: . :..:.:..::.:.::
XP_016 LGATAGMRLLRMESEELADRVLDVVERSLSNYP--FDF----QGARIITGQEEGAYGWIT
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE5 INFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEV
::..::.: .. . .: :... ..: : ::.::.:::... ::... .
XP_016 INYLLGKF------SQKTRWFSIVPYETNN----QETFGALDLGGASTQVTF-VPQNQTI
200 210 220 230 240
290 300 310 320 330 340
pF1KE5 AK--NLLAEFNL-GCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGK
. : : .: : : : : ::. .:: .: . :
XP_016 ESPDNAL-QFRLYGKD-------YNVYTHSFLCYGKDQALWQKLAKDIQMPSAF
250 260 270 280
350 360 370 380 390 400
pF1KE5 QTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLN
>>NP_001157651 (OMIM: 601752,615683) ectonucleoside trip (469 aa)
initn: 463 init1: 230 opt: 333 Z-score: 416.5 bits: 86.7 E(85289): 1.8e-16
Smith-Waterman score: 514; 27.9% identity (57.0% similar) in 458 aa overlap (86-531:46-422)
60 70 80 90 100 110
pF1KE5 NKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPH
::.::::.: ::: . ...: :: .. :
NP_001 NILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKEN--
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE5 DLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLY
: ..:... : ::::.:. . .... :.. .. : : .::..:.:::.:
NP_001 DTGVVHQVEECRVKG------PGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVY
80 90 100 110 120
180 190 200 210 220
pF1KE5 ILCTAGMRILP-ESQQKA-----ILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIG
. :::::.: ::.. : ..: :.. : ::: . :..:.:..::.:.::
NP_001 LGATAGMRLLRMESEELADRVLDVVERSLSNYP--FDF----QGARIITGQEEGAYGWIT
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE5 INFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEV
::..::.: .. . .: :... ..: : ::.::.:::... ::... .
NP_001 INYLLGKF------SQKTRWFSIVPYETNN----QETFGALDLGGASTQVTF-VPQNQTI
190 200 210 220 230
290 300 310 320 330 340
pF1KE5 AK--NLLAEFNL-GCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGK
. : : .: : : : : ::. .:: .: . : :: :.:
NP_001 ESPDNAL-QFRLYGKD-------YNVYTHSFLCYGKDQA-----------LWQK---LAK
240 250 260
350 360 370 380 390 400
pF1KE5 QTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN--ETQTS
.::: . ..: :... :...: ..: . .: .
NP_001 ---------------------DIQQ----FEIQGIGNYQQCHQSILELFNTSYCPYSQCA
270 280 290 300
410 420 430 440 450 460
pF1KE5 LNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERF
.::.. ::.. ..: .:: ::. . . . . : :. : .:: : ..
NP_001 FNGIFLPPLQ---GDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTS-
310 320 330 340 350
470 480 490 500 510 520
pF1KE5 DRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVN-YKSLKTALQVYDKEVQWTLGAI
::. . . .: ::...... .. .:. : .. .. .. .. ... :::: .
NP_001 ----YAGVKEKYLSEY-CFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYM
360 370 380 390 400 410
530 540 550 560 570
pF1KE5 LYRTRFLPLRKIGMLIIPCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
: : ..:
NP_001 LNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDMV
420 430 440 450 460
>>XP_016872447 (OMIM: 601752,615683) PREDICTED: ectonucl (470 aa)
initn: 439 init1: 230 opt: 333 Z-score: 416.5 bits: 86.7 E(85289): 1.9e-16
Smith-Waterman score: 539; 28.6% identity (59.6% similar) in 433 aa overlap (86-501:46-432)
60 70 80 90 100 110
pF1KE5 NKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPH
::.::::.: ::: . ...: :: .. :
XP_016 NILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKEN--
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE5 DLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLY
: ..:... : ::::.:. . .... :.. .. : : .::..:.:::.:
XP_016 DTGVVHQVEECRVKG------PGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVY
80 90 100 110 120
180 190 200 210 220
pF1KE5 ILCTAGMRILP-ESQQKA-----ILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIG
. :::::.: ::.. : ..: :.. : ::: . :..:.:..::.:.::
XP_016 LGATAGMRLLRMESEELADRVLDVVERSLSNYP--FDF----QGARIITGQEEGAYGWIT
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE5 INFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEV
::..::.: .. . .: :... ..: : ::.::.:::... ::... .
XP_016 INYLLGKF------SQKTRWFSIVPYETNN----QETFGALDLGGASTQVTF-VPQNQTI
190 200 210 220 230
290 300 310 320 330 340
pF1KE5 AK--NLLAEFNL-GCDVHQTEHVYRVYVATFLGFGGNAA--RQRYED-RIFANTIQKNRL
. : : .: : : : : ::. .:: .: . : .. .: .. .: : ..
XP_016 ESPDNAL-QFRLYGKD-------YNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPC
240 250 260 270 280
350 360 370 380 390
pF1KE5 LG---KQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN-
. :.. . :. : :: . :. : . ..: :... :...: ..: .
XP_016 FHPGYKKVVNVSDL-YKTPCTK---RFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYC
290 300 310 320 330
400 410 420 430 440 450
pF1KE5 -ETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWS
.: ..::.. ::.. ..: .:: ::. . . . . : :. : .:: :
XP_016 PYSQCAFNGIFLPPLQ---GDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWE
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE5 ILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQW
.. ::. . . .: ::...... .. .:. : ..
XP_016 EIKTS-----YAGVKEKYLSEY-CFSGTYILSLLLQGYHFTADSWEHIHFIGKSTEPSSW
400 410 420 430 440
520 530 540 550 560 570
pF1KE5 TLGAILYRTRFLPLRKIGMLIIPCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
XP_016 STHEDGSLHGEYRMNPLCLLQ
450 460 470
>>NP_001307845 (OMIM: 601752,615683) ectonucleoside trip (482 aa)
initn: 439 init1: 230 opt: 333 Z-score: 416.3 bits: 86.7 E(85289): 1.9e-16
Smith-Waterman score: 539; 28.6% identity (59.6% similar) in 433 aa overlap (86-501:58-444)
60 70 80 90 100 110
pF1KE5 NKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPH
::.::::.: ::: . ...: :: .. :
NP_001 NILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKEN--
30 40 50 60 70 80
120 130 140 150 160 170
pF1KE5 DLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLY
: ..:... : ::::.:. . .... :.. .. : : .::..:.:::.:
NP_001 DTGVVHQVEECRVKG------PGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVY
90 100 110 120 130
180 190 200 210 220
pF1KE5 ILCTAGMRILP-ESQQKA-----ILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIG
. :::::.: ::.. : ..: :.. : ::: . :..:.:..::.:.::
NP_001 LGATAGMRLLRMESEELADRVLDVVERSLSNYP--FDF----QGARIITGQEEGAYGWIT
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE5 INFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEV
::..::.: .. . .: :... ..: : ::.::.:::... ::... .
NP_001 INYLLGKF------SQKTRWFSIVPYETNN----QETFGALDLGGASTQVTF-VPQNQTI
200 210 220 230 240
290 300 310 320 330 340
pF1KE5 AK--NLLAEFNL-GCDVHQTEHVYRVYVATFLGFGGNAA--RQRYED-RIFANTIQKNRL
. : : .: : : : : ::. .:: .: . : .. .: .. .: : ..
NP_001 ESPDNAL-QFRLYGKD-------YNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPC
250 260 270 280 290
350 360 370 380 390
pF1KE5 LG---KQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN-
. :.. . :. : :: . :. : . ..: :... :...: ..: .
NP_001 FHPGYKKVVNVSDL-YKTPCTK---RFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYC
300 310 320 330 340 350
400 410 420 430 440 450
pF1KE5 -ETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWS
.: ..::.. ::.. ..: .:: ::. . . . . : :. : .:: :
NP_001 PYSQCAFNGIFLPPLQ---GDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWE
360 370 380 390 400
460 470 480 490 500 510
pF1KE5 ILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQW
.. ::. . . .: ::...... .. .:. : ..
NP_001 EIKTS-----YAGVKEKYLSEY-CFSGTYILSLLLQGYHFTADSWEHIHFIGKSTEPSSW
410 420 430 440 450 460
520 530 540 550 560 570
pF1KE5 TLGAILYRTRFLPLRKIGMLIIPCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
NP_001 STHEDGSLHGEYRMNPLCLLQ
470 480
>>NP_001767 (OMIM: 601752,615683) ectonucleoside triphos (510 aa)
initn: 463 init1: 230 opt: 333 Z-score: 416.0 bits: 86.7 E(85289): 2e-16
Smith-Waterman score: 577; 28.2% identity (59.7% similar) in 464 aa overlap (86-531:46-463)
60 70 80 90 100 110
pF1KE5 NKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPH
::.::::.: ::: . ...: :: .. :
NP_001 NILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKEN--
20 30 40 50 60 70
120 130 140 150 160 170
pF1KE5 DLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLY
: ..:... : ::::.:. . .... :.. .. : : .::..:.:::.:
NP_001 DTGVVHQVEECRVKG------PGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVY
80 90 100 110 120
180 190 200 210 220
pF1KE5 ILCTAGMRILP-ESQQKA-----ILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIG
. :::::.: ::.. : ..: :.. : ::: . :..:.:..::.:.::
NP_001 LGATAGMRLLRMESEELADRVLDVVERSLSNYP--FDF----QGARIITGQEEGAYGWIT
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE5 INFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEV
::..::.: .. . .: :... ..: : ::.::.:::... ::... .
NP_001 INYLLGKF------SQKTRWFSIVPYETNN----QETFGALDLGGASTQVTF-VPQNQTI
190 200 210 220 230
290 300 310 320 330 340
pF1KE5 AK--NLLAEFNL-GCDVHQTEHVYRVYVATFLGFGGNAA--RQRYED-RIFANTIQKNRL
. : : .: : : : : ::. .:: .: . : .. .: .. .: : ..
NP_001 ESPDNAL-QFRLYGKD-------YNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPC
240 250 260 270 280
350 360 370 380 390
pF1KE5 LG---KQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN-
. :.. . :. : :: . :. : . ..: :... :...: ..: .
NP_001 FHPGYKKVVNVSDL-YKTPCTK---RFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYC
290 300 310 320 330
400 410 420 430 440 450
pF1KE5 -ETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWS
.: ..::.. ::.. ..: .:: ::. . . . . : :. : .:: :
NP_001 PYSQCAFNGIFLPPLQ---GDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWE
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE5 ILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVN-YKSLKTALQVYDKEVQ
.. ::. . . .: ::...... .. .:. : .. .. .. .. ...
NP_001 EIKTS-----YAGVKEKYLSEY-CFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAG
400 410 420 430 440
520 530 540 550 560 570
pF1KE5 WTLGAILYRTRFLPLRKIGMLIIPCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
:::: .: : ..:
NP_001 WTLGYMLNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDM
450 460 470 480 490 500
>>XP_011538673 (OMIM: 601752,615683) PREDICTED: ectonucl (517 aa)
initn: 463 init1: 230 opt: 333 Z-score: 415.9 bits: 86.7 E(85289): 2e-16
Smith-Waterman score: 577; 28.2% identity (59.7% similar) in 464 aa overlap (86-531:53-470)
60 70 80 90 100 110
pF1KE5 NKYGRLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPH
::.::::.: ::: . ...: :: .. :
XP_011 NILAILGFSSIIAVIALLAVGLTQNKALPENVKYGIVLDAGSSHTSLYIYKWPAEKEN--
30 40 50 60 70 80
120 130 140 150 160 170
pF1KE5 DLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLY
: ..:... : ::::.:. . .... :.. .. : : .::..:.:::.:
XP_011 DTGVVHQVEECRVKG------PGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVY
90 100 110 120 130
180 190 200 210 220
pF1KE5 ILCTAGMRILP-ESQQKA-----ILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIG
. :::::.: ::.. : ..: :.. : ::: . :..:.:..::.:.::
XP_011 LGATAGMRLLRMESEELADRVLDVVERSLSNYP--FDF----QGARIITGQEEGAYGWIT
140 150 160 170 180
230 240 250 260 270 280
pF1KE5 INFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEV
::..::.: .. . .: :... ..: : ::.::.:::... ::... .
XP_011 INYLLGKF------SQKTRWFSIVPYETNN----QETFGALDLGGASTQVTF-VPQNQTI
190 200 210 220 230
290 300 310 320 330 340
pF1KE5 AK--NLLAEFNL-GCDVHQTEHVYRVYVATFLGFGGNAA--RQRYED-RIFANTIQKNRL
. : : .: : : : : ::. .:: .: . : .. .: .. .: : ..
XP_011 ESPDNAL-QFRLYGKD-------YNVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPC
240 250 260 270 280
350 360 370 380 390
pF1KE5 LG---KQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN-
. :.. . :. : :: . :. : . ..: :... :...: ..: .
XP_011 FHPGYKKVVNVSDL-YKTPCTK---RFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYC
290 300 310 320 330 340
400 410 420 430 440 450
pF1KE5 -ETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWS
.: ..::.. ::.. ..: .:: ::. . . . . : :. : .:: :
XP_011 PYSQCAFNGIFLPPLQ---GDFGAFSAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWE
350 360 370 380 390 400
460 470 480 490 500 510
pF1KE5 ILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHRGFSFPVN-YKSLKTALQVYDKEVQ
.. ::. . . .: ::...... .. .:. : .. .. .. .. ...
XP_011 EIKTS-----YAGVKEKYLSEY-CFSGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAG
410 420 430 440 450
520 530 540 550 560 570
pF1KE5 WTLGAILYRTRFLPLRKIGMLIIPCSGGCPKLCCAVWQPPPYGATKHLQCAAWN
:::: .: : ..:
XP_011 WTLGYMLNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLFTVAIIGLLIFHKPSYFWKDM
460 470 480 490 500 510
571 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:10:43 2016 done: Tue Nov 8 05:10:44 2016
Total Scan time: 7.990 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]