Result of FASTA (omim) for
pFN21AE5576
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5576, 390 aa
1>>>pF1KE5576 390 - 390 aa - 390 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4640+/-0.000476; mu= 9.7922+/- 0.030
mean_var=282.7037+/-62.743, 0's: 0 Z-trim(117.8): 168 B-trim: 1461 in 1/55
Lambda= 0.076280
statistics sampled from 29892 (30108) to 29892 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.353), width: 16
Scan time: 5.890
The best scores are: opt bits E(85289)
NP_065096 (OMIM: 400026,415000) deleted in azoospe ( 558) 2480 286.7 9.1e-77
NP_001005785 (OMIM: 400026,415000) deleted in azoo ( 534) 2468 285.4 2.2e-76
XP_011529785 (OMIM: 400003,415000) PREDICTED: dele ( 529) 2461 284.6 3.8e-76
XP_011529784 (OMIM: 400003,415000) PREDICTED: dele ( 694) 2461 284.8 4.4e-76
NP_004072 (OMIM: 400003,415000) deleted in azoospe ( 744) 2461 284.8 4.6e-76
NP_065097 (OMIM: 400027,415000) deleted in azoospe ( 438) 2447 282.9 9.8e-76
NP_001005786 (OMIM: 400026,415000) deleted in azoo ( 366) 2252 261.4 2.6e-69
NP_001342 (OMIM: 601486) deleted in azoospermia-li ( 295) 1077 131.9 1.9e-30
NP_001177740 (OMIM: 601486) deleted in azoospermia ( 315) 1070 131.2 3.4e-30
NP_149019 (OMIM: 606165) protein boule-like isofor ( 283) 332 49.9 8.9e-06
NP_001271291 (OMIM: 606165) protein boule-like iso ( 289) 332 49.9 9e-06
XP_006712778 (OMIM: 606165) PREDICTED: protein bou ( 291) 332 49.9 9.1e-06
NP_932074 (OMIM: 606165) protein boule-like isofor ( 295) 332 49.9 9.1e-06
XP_016860262 (OMIM: 606165) PREDICTED: protein bou ( 220) 323 48.8 1.5e-05
XP_011509996 (OMIM: 606165) PREDICTED: protein bou ( 305) 323 49.0 1.8e-05
XP_011509995 (OMIM: 606165) PREDICTED: protein bou ( 313) 323 49.0 1.9e-05
XP_011509994 (OMIM: 606165) PREDICTED: protein bou ( 317) 323 49.0 1.9e-05
NP_001271290 (OMIM: 606165) protein boule-like iso ( 339) 323 49.0 2e-05
XP_005259588 (OMIM: 607430) PREDICTED: DAZ-associa ( 406) 250 41.1 0.0057
XP_011526208 (OMIM: 607430) PREDICTED: DAZ-associa ( 549) 250 41.3 0.0068
>>NP_065096 (OMIM: 400026,415000) deleted in azoospermia (558 aa)
initn: 2469 init1: 2469 opt: 2480 Z-score: 1499.2 bits: 286.7 E(85289): 9.1e-77
Smith-Waterman score: 2480; 98.1% identity (98.4% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 PAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMP
:::::::::::::::::::::::::::::::::::::::::: ::::::::. :::::
NP_065 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAF
310 320 330 340 350 360
370 380 390
pF1KE5 PQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
: :
NP_065 PAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTT
370 380 390 400 410 420
>--
initn: 1305 init1: 1305 opt: 1305 Z-score: 800.4 bits: 157.4 E(85289): 7.7e-38
Smith-Waterman score: 1305; 92.7% identity (97.4% similar) in 193 aa overlap (198-390:366-558)
170 180 190 200 210 220
pF1KE5 YSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVT
: ::::::::::::::: ::::: ::::::
NP_065 FPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVT
340 350 360 370 380 390
230 240 250 260 270 280
pF1KE5 AGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQA
.::::::::::::::::.:::::.::::.:::::: ::::::::::::.:::::::::::
NP_065 TGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQA
400 410 420 430 440 450
290 300 310 320 330 340
pF1KE5 FPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVT
:::::.:::::.::::.::::::::::::.:: :::::::::::::::::::::::::::
NP_065 FPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVT
460 470 480 490 500 510
350 360 370 380 390
pF1KE5 TGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
:::::::::::::::::::::::::::::::::::::::::::
NP_065 TGYQFHVYNYQMPPQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
520 530 540 550
>>NP_001005785 (OMIM: 400026,415000) deleted in azoosper (534 aa)
initn: 2457 init1: 2457 opt: 2468 Z-score: 1492.3 bits: 285.4 E(85289): 2.2e-76
Smith-Waterman score: 2468; 97.5% identity (98.1% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 PAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMP
::::::::::::::::::::::::::::::::::::::::.: :::::::. :::::
NP_001 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAF
310 320 330 340 350 360
370 380 390
pF1KE5 PQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
: :
NP_001 PAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTT
370 380 390 400 410 420
>--
initn: 1159 init1: 1159 opt: 1159 Z-score: 713.7 bits: 141.3 E(85289): 5.1e-33
Smith-Waterman score: 1159; 93.5% identity (98.8% similar) in 169 aa overlap (222-390:366-534)
200 210 220 230 240 250
pF1KE5 YPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVA
::::::.::::::::::::::::.:::::.
NP_001 FPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVT
340 350 360 370 380 390
260 270 280 290 300 310
pF1KE5 TGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQA
::::.:::::: ::::::::::::.::::::::::::::::.:::::.::::.:::::::
NP_001 TGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQA
400 410 420 430 440 450
320 330 340 350 360 370
pF1KE5 FPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRN
:::::.:: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRN
460 470 480 490 500 510
380 390
pF1KE5 LWTEAYKWWYLVCLIQRRD
:::::::::::::::::::
NP_001 LWTEAYKWWYLVCLIQRRD
520 530
>>XP_011529785 (OMIM: 400003,415000) PREDICTED: deleted (529 aa)
initn: 2450 init1: 2450 opt: 2461 Z-score: 1488.1 bits: 284.6 E(85289): 3.8e-76
Smith-Waterman score: 2683; 94.2% identity (94.2% similar) in 413 aa overlap (2-390:117-529)
10 20 30
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE5 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
390 400 410 420 430 440
340 350 360
pF1KE5 NYQAFPAYP------------------------NSAVQVTTGYQFHVYNYQMPPQCPVGE
::::::::: :::::::::::::::::::::::::::
XP_011 NYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGE
450 460 470 480 490 500
370 380 390
pF1KE5 QRRNLWTEAYKWWYLVCLIQRRD
:::::::::::::::::::::::
XP_011 QRRNLWTEAYKWWYLVCLIQRRD
510 520
>--
initn: 807 init1: 807 opt: 807 Z-score: 504.4 bits: 102.6 E(85289): 2.3e-21
Smith-Waterman score: 807; 100.0% identity (100.0% similar) in 116 aa overlap (51-166:1-116)
30 40 50 60 70 80
pF1KE5 SSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSK
::::::::::::::::::::::::::::::
XP_011 MDETEIGSCFGRYGSVKEVKIITNRTGVSK
10 20 30
90 100 110 120 130 140
pF1KE5 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 NVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAF
::::::::::::::::::::::::::
XP_011 NVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEG
100 110 120 130 140 150
>>XP_011529784 (OMIM: 400003,415000) PREDICTED: deleted (694 aa)
initn: 2450 init1: 2450 opt: 2461 Z-score: 1486.9 bits: 284.8 E(85289): 4.4e-76
Smith-Waterman score: 2683; 94.2% identity (94.2% similar) in 413 aa overlap (2-390:282-694)
10 20 30
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
260 270 280 290 300 310
40 50 60 70 80 90
pF1KE5 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
320 330 340 350 360 370
100 110 120 130 140 150
pF1KE5 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
380 390 400 410 420 430
160 170 180 190 200 210
pF1KE5 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
440 450 460 470 480 490
220 230 240 250 260 270
pF1KE5 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
500 510 520 530 540 550
280 290 300 310 320 330
pF1KE5 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
560 570 580 590 600 610
340 350 360
pF1KE5 NYQAFPAYP------------------------NSAVQVTTGYQFHVYNYQMPPQCPVGE
::::::::: :::::::::::::::::::::::::::
XP_011 NYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGE
620 630 640 650 660 670
370 380 390
pF1KE5 QRRNLWTEAYKWWYLVCLIQRRD
:::::::::::::::::::::::
XP_011 QRRNLWTEAYKWWYLVCLIQRRD
680 690
>--
initn: 1118 init1: 1118 opt: 1118 Z-score: 688.2 bits: 137.0 E(85289): 1.4e-31
Smith-Waterman score: 1118; 100.0% identity (100.0% similar) in 165 aa overlap (2-166:117-281)
10 20 30
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
XP_011 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
:::::::::::::::
XP_011 LQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGG
270 280 290 300 310 320
>--
initn: 807 init1: 807 opt: 807 Z-score: 503.2 bits: 102.7 E(85289): 2.7e-21
Smith-Waterman score: 807; 100.0% identity (100.0% similar) in 116 aa overlap (51-166:1-116)
30 40 50 60 70 80
pF1KE5 SSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSK
::::::::::::::::::::::::::::::
XP_011 MDETEIGSCFGRYGSVKEVKIITNRTGVSK
10 20 30
90 100 110 120 130 140
pF1KE5 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 NVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAF
::::::::::::::::::::::::::
XP_011 NVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEG
100 110 120 130 140 150
>>NP_004072 (OMIM: 400003,415000) deleted in azoospermia (744 aa)
initn: 2450 init1: 2450 opt: 2461 Z-score: 1486.6 bits: 284.8 E(85289): 4.6e-76
Smith-Waterman score: 2683; 94.2% identity (94.2% similar) in 413 aa overlap (2-390:332-744)
10 20 30
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWV
::::::::::::::::::::::::::::::
NP_004 PQFQNVWRNPNTETYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWV
310 320 330 340 350 360
40 50 60 70 80 90
pF1KE5 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDV
370 380 390 400 410 420
100 110 120 130 140 150
pF1KE5 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DVQKIVGSQIHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETY
430 440 450 460 470 480
160 170 180 190 200 210
pF1KE5 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LQPQITPNPVTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVY
490 500 510 520 530 540
220 230 240 250 260 270
pF1KE5 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSP
550 560 570 580 590 600
280 290 300 310 320 330
pF1KE5 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVY
610 620 630 640 650 660
340 350 360
pF1KE5 NYQAFPAYP------------------------NSAVQVTTGYQFHVYNYQMPPQCPVGE
::::::::: :::::::::::::::::::::::::::
NP_004 NYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGE
670 680 690 700 710 720
370 380 390
pF1KE5 QRRNLWTEAYKWWYLVCLIQRRD
:::::::::::::::::::::::
NP_004 QRRNLWTEAYKWWYLVCLIQRRD
730 740
>--
initn: 1142 init1: 1126 opt: 1147 Z-score: 705.1 bits: 140.2 E(85289): 1.5e-32
Smith-Waterman score: 1147; 94.4% identity (98.9% similar) in 180 aa overlap (1-180:1-179)
10 20 30 40 50 60
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::. .: :..:...:.
NP_004 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQS-AANPETPNSTIS
130 140 150 160 170
190 200 210 220 230 240
pF1KE5 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
NP_004 REASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYGSVKEVKIITN
180 190 200 210 220 230
>--
initn: 1038 init1: 1038 opt: 1038 Z-score: 640.3 bits: 128.2 E(85289): 6.3e-29
Smith-Waterman score: 1038; 100.0% identity (100.0% similar) in 152 aa overlap (15-166:180-331)
10 20 30 40
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFV
::::::::::::::::::::::::::::::
NP_004 TYLQPQITPNPVTQHVQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFV
150 160 170 180 190 200
50 60 70 80 90 100
pF1KE5 GGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFH
210 220 230 240 250 260
110 120 130 140 150 160
pF1KE5 GKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQH
270 280 290 300 310 320
170 180 190 200 210 220
pF1KE5 VQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPF
::
NP_004 VQSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSC
330 340 350 360 370 380
>>NP_065097 (OMIM: 400027,415000) deleted in azoospermia (438 aa)
initn: 2436 init1: 2436 opt: 2447 Z-score: 1480.6 bits: 282.9 E(85289): 9.8e-76
Smith-Waterman score: 2489; 87.9% identity (88.4% similar) in 422 aa overlap (1-374:1-422)
10 20 30 40 50 60
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260
pF1KE5 PAYPNSPFQVATGYQFPVYNYQ--P-----------------------------------
:::::::::::::::::::::: :
NP_065 PAYPNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVAT
250 260 270 280 290 300
270 280 290 300 310
pF1KE5 -----------FPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAF
:::::.:: :::.::::::::::::::::::::::::::::::::::::
NP_065 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQAF
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE5 PAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 PAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMPPQCPVGEQRRNL
370 380 390 400 410 420
380 390
pF1KE5 WTEAYKWWYLVCLIQRRD
::
NP_065 WTEAYKWWYLVCLIQRRD
430
>>NP_001005786 (OMIM: 400026,415000) deleted in azoosper (366 aa)
initn: 2241 init1: 2241 opt: 2252 Z-score: 1365.5 bits: 261.4 E(85289): 2.6e-69
Smith-Waterman score: 2471; 92.1% identity (93.3% similar) in 390 aa overlap (1-390:1-366)
10 20 30 40 50 60
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 PAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVAT
::::.:::::.::::.:::::: ::::::::::::.::::::::::::::::.:::::
NP_001 PAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFPAYPSSPFQV--
250 260 270 280 290
310 320 330 340 350 360
pF1KE5 GYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMP
::::::::::::::::::::::::::::::::::::::
NP_001 ----------------------TTGYQLPVYNYQAFPAYPNSAVQVTTGYQFHVYNYQMP
300 310 320 330
370 380 390
pF1KE5 PQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
::::::::::::::::::::::::::::::
NP_001 PQCPVGEQRRNLWTEAYKWWYLVCLIQRRD
340 350 360
>>NP_001342 (OMIM: 601486) deleted in azoospermia-like i (295 aa)
initn: 1061 init1: 1061 opt: 1077 Z-score: 667.6 bits: 131.9 E(85289): 1.9e-30
Smith-Waterman score: 1077; 82.7% identity (90.8% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCF
::.::::::::::::::::::::::.:::..::::::.::::::::::.::::::: : :
NP_001 MSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQIHFHGKKLKLGPAIRKQKLC
.::::::::::::.::::::::::::: ::::::::: :::.:::::::::::::::.::
NP_001 ARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQHVQAYSAYPHSPGQVIT
: :::::::: : :::::::::: :::::::.:: : ::.::.:::: .::.:: ::::
NP_001 AYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNPITQYVQAYPTYPNSPVQVIT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAF
: :: ::::: : .:
NP_001 GYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSG
190 200 210 220 230 240
>>NP_001177740 (OMIM: 601486) deleted in azoospermia-lik (315 aa)
initn: 1054 init1: 1054 opt: 1070 Z-score: 663.1 bits: 131.2 E(85289): 3.4e-30
Smith-Waterman score: 1070; 82.6% identity (90.8% similar) in 195 aa overlap (2-196:22-216)
10 20 30 40
pF1KE5 MSAANPETPNSTISREASTQSSSAAASQGWVLPEGKIVPN
:.::::::::::::::::::::::.:::..::::::.::
NP_001 MAAPSCGGDRKARLTPSLPHESTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 TVFVGGIDARMDETEIGSCFGRYGSVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIVGSQ
::::::::.::::::: : :.::::::::::::.::::::::::::: ::::::::: ::
NP_001 TVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 IHFHGKKLKLGPAIRKQKLCARHVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNP
:.:::::::::::::::.::: :::::::: : :::::::::: :::::::.:: : ::
NP_001 INFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 VTQHVQAYSAYPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQPFPAYP
.::.:::: .::.:: ::::: :: ::::: : .:
NP_001 ITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 RSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQL
NP_001 PGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCLFNPENRLRNSVVTQDDYFKDK
250 260 270 280 290 300
>>NP_149019 (OMIM: 606165) protein boule-like isoform 2 (283 aa)
initn: 437 init1: 257 opt: 332 Z-score: 224.7 bits: 49.9 E(85289): 8.9e-06
Smith-Waterman score: 337; 35.7% identity (60.2% similar) in 196 aa overlap (35-224:28-208)
10 20 30 40 50 60
pF1KE5 NPETPNSTISREASTQSSSAAASQGWVLPEGKIVPNTVFVGGIDARMDETEIGSCFGRYG
: ..:: .:::::: . .:... . :..::
NP_149 MQTDSLSPSPNPVSPVPLNNPTSAPRYGTVIPNRIFVGGIDFKTNESDLRKFFSQYG
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 SVKEVKIITNRTGVSKGYGFVSFVNDVDVQKIV--GSQIHFHGKKLKLGPAIRKQKLCAR
:::::::...:.:::::::::.: .. :.:::. . ..... :::..:::::::..
NP_149 SVKEVKIVNDRAGVSKGYGFVTFETQEDAQKILQEAEKLNYKDKKLNIGPAIRKQQVGI-
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 HVQPRPLVVNPPPPPQFQNVWRNPNTETYLQPQITPNPVTQ-HVQAYSAYPHSPGQVITG
:: .. : .. : . : : :. :. .. : : .
NP_149 ---PRSSIM-PAAGTMYL-------TTSTGYPYTYHNGVAYFHTPEVTSVP-PPWPSRSV
120 130 140 150 160
190 200 210 220 230
pF1KE5 CQLLVYNYQEYPTYPDSAFQVTTGYQLPVYNYQ---PFPAYPRSPFQVTAGYQLPVYNYQ
:. :. : : .:.:: : :: ..: : :. .::
NP_149 CSSPVMVAQPIYQQPAYHYQATTQY-LP-GQWQWSVPQPSASSAPFLYLQPSEVIYQPVE
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 AFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQV
NP_149 IAQDGGCVPPPLSLMETSVPEPYSDHGVQATYHQVYAPSAITMPAPVMQPEPIKTVWSIH
230 240 250 260 270 280
390 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:00:03 2016 done: Tue Nov 8 02:00:04 2016
Total Scan time: 5.890 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]