Result of FASTA (omim) for
pFN21AE5568
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5568, 431 aa
1>>>pF1KE5568 431 - 431 aa - 431 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6648+/-0.000383; mu= -1.9563+/- 0.024
mean_var=246.2413+/-50.161, 0's: 0 Z-trim(121.3): 22 B-trim: 598 in 1/56
Lambda= 0.081732
statistics sampled from 37784 (37806) to 37784 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.767), E-opt: 0.2 (0.443), width: 16
Scan time: 10.240
The best scores are: opt bits E(85289)
NP_001002036 (OMIM: 608860) astacin-like metalloen ( 431) 2947 360.3 5.4e-99
XP_011509507 (OMIM: 608860) PREDICTED: astacin-lik ( 436) 2828 346.3 9.1e-95
XP_011509508 (OMIM: 608860) PREDICTED: astacin-lik ( 432) 2813 344.5 3.1e-94
XP_011509510 (OMIM: 608860) PREDICTED: astacin-lik ( 252) 1518 191.7 1.9e-48
XP_011509509 (OMIM: 608860) PREDICTED: astacin-lik ( 418) 1516 191.6 3.3e-48
NP_001295100 (OMIM: 600389) meprin A subunit beta ( 700) 464 67.7 1.1e-10
NP_005916 (OMIM: 600389) meprin A subunit beta iso ( 701) 464 67.7 1.1e-10
XP_011542919 (OMIM: 112264,614856) PREDICTED: bone ( 622) 446 65.5 4.3e-10
XP_016869227 (OMIM: 112264,614856) PREDICTED: bone ( 717) 446 65.6 4.8e-10
NP_001190 (OMIM: 112264,614856) bone morphogenetic ( 730) 446 65.6 4.9e-10
NP_036597 (OMIM: 606743) tolloid-like protein 2 pr (1015) 449 66.0 5e-10
XP_006716449 (OMIM: 112264,614856) PREDICTED: bone ( 813) 446 65.6 5.3e-10
NP_006120 (OMIM: 112264,614856) bone morphogenetic ( 986) 446 65.7 6.2e-10
NP_001191689 (OMIM: 606742,613087) tolloid-like pr ( 392) 435 64.1 7.3e-10
XP_016864059 (OMIM: 606742,613087) PREDICTED: toll ( 964) 435 64.4 1.5e-09
NP_036596 (OMIM: 606742,613087) tolloid-like prote (1013) 435 64.4 1.6e-09
XP_011512931 (OMIM: 600388) PREDICTED: meprin A su ( 705) 419 62.4 4.3e-09
NP_005579 (OMIM: 600388) meprin A subunit alpha pr ( 746) 419 62.4 4.5e-09
XP_011512930 (OMIM: 600388) PREDICTED: meprin A su ( 774) 419 62.4 4.6e-09
XP_011530516 (OMIM: 606742,613087) PREDICTED: toll ( 837) 397 59.8 3e-08
XP_011524316 (OMIM: 600389) PREDICTED: meprin A su ( 577) 317 50.3 1.5e-05
XP_011524315 (OMIM: 600389) PREDICTED: meprin A su ( 628) 315 50.1 1.9e-05
>>NP_001002036 (OMIM: 608860) astacin-like metalloendope (431 aa)
initn: 2947 init1: 2947 opt: 2947 Z-score: 1898.2 bits: 360.3 E(85289): 5.4e-99
Smith-Waterman score: 2947; 99.5% identity (100.0% similar) in 431 aa overlap (1-431:1-431)
10 20 30 40 50 60
pF1KE5 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSVMHYGR
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_001 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHAHSTGR
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_001 LAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 RQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCV
370 380 390 400 410 420
430
pF1KE5 PRNHFKGMSED
:::::::::::
NP_001 PRNHFKGMSED
430
>>XP_011509507 (OMIM: 608860) PREDICTED: astacin-like me (436 aa)
initn: 2828 init1: 2828 opt: 2828 Z-score: 1822.3 bits: 346.3 E(85289): 9.1e-95
Smith-Waterman score: 2828; 99.3% identity (99.8% similar) in 417 aa overlap (15-431:20-436)
10 20 30 40 50
pF1KE5 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDI
:: ::::::::::::::::::::::::::::::::::::::
XP_011 MSCCLVSPVGAPGICVCPCLSGPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 PAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 SRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 GRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSV
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_011 GRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 MHYGRLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHA
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 MHYGRLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 HSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 AEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPAL
370 380 390 400 410 420
420 430
pF1KE5 PGGCVPRNHFKGMSED
::::::::::::::::
XP_011 PGGCVPRNHFKGMSED
430
>>XP_011509508 (OMIM: 608860) PREDICTED: astacin-like me (432 aa)
initn: 2812 init1: 2812 opt: 2813 Z-score: 1812.8 bits: 344.5 E(85289): 3.1e-94
Smith-Waterman score: 2813; 98.3% identity (99.0% similar) in 420 aa overlap (12-431:13-432)
10 20 30 40 50
pF1KE5 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAIN
: :. :::::::::::::::::::::::::::::::::::::::::
XP_011 MGPSSLRKTSSGLPLILHYGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAIN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 QGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 ILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 VLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSVMHYG
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_011 VLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 RLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHAHSTG
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_011 RLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 RSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEAS
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 ARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGC
370 380 390 400 410 420
420 430
pF1KE5 VPRNHFKGMSED
::::::::::::
XP_011 VPRNHFKGMSED
430
>>XP_011509510 (OMIM: 608860) PREDICTED: astacin-like me (252 aa)
initn: 1518 init1: 1518 opt: 1518 Z-score: 990.9 bits: 191.7 E(85289): 1.9e-48
Smith-Waterman score: 1518; 98.7% identity (99.6% similar) in 227 aa overlap (15-241:20-246)
10 20 30 40 50
pF1KE5 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDI
:: ::::::::::::::::::::::::::::::::::::::
XP_011 MSCCLVSPVGAPGICVCPCLSGPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 PAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 SRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 GRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSV
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_011 GRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 MHYGRLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHA
:::::.
XP_011 MHYGRVPCPQHW
250
>>XP_011509509 (OMIM: 608860) PREDICTED: astacin-like me (418 aa)
initn: 1589 init1: 1516 opt: 1516 Z-score: 986.5 bits: 191.6 E(85289): 3.3e-48
Smith-Waterman score: 2655; 95.0% identity (95.4% similar) in 417 aa overlap (15-431:20-418)
10 20 30 40 50
pF1KE5 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDI
:: ::::::::::::::::::::::::::::::::::::::
XP_011 MSCCLVSPVGAPGICVCPCLSGPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 PAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 SRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 GRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSV
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
XP_011 GRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 MHYGRLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHA
:::: :::::::::::::::::::.::::::::::::::::::
XP_011 MHYG------------------SVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHA
250 260 270 280
300 310 320 330 340 350
pF1KE5 HSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLS
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE5 AEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPAL
350 360 370 380 390 400
420 430
pF1KE5 PGGCVPRNHFKGMSED
::::::::::::::::
XP_011 PGGCVPRNHFKGMSED
410
>>NP_001295100 (OMIM: 600389) meprin A subunit beta isof (700 aa)
initn: 462 init1: 186 opt: 464 Z-score: 312.9 bits: 67.7 E(85289): 1.1e-10
Smith-Waterman score: 501; 37.8% identity (63.8% similar) in 254 aa overlap (41-284:20-258)
20 30 40 50 60
pF1KE5 VLGLLSLPGVILGAPLASSCAGACGTSFPDGL-TPEGTQASG--DKDIPAINQGLILEET
:: :::. ...: :.:: ::.:: :.
NP_001 MDLWNLSWFLFLDALLVISGLATPENFDVDGGMDQDIFDINEGLGLD--
10 20 30 40
70 80 90 100 110 120
pF1KE5 PESSFLIEGDII--RPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALA
:.:::: : . . . . .:: .:..: .. . .. :::.:.
NP_001 -----LFEGDIRLDRAQIRNSIIGEKYRWPH------TIPYVLEDSLEMNAKGVILNAFE
50 60 70 80 90
130 140 150 160 170 180
pF1KE5 EFERSTCIRFVTYQDQRDFISIIPMYGCFSSVG-RSGGMQVVSLAPTCLQKGRGIVLHEL
... .::: : . . ..::.. ::.:::: : : : .:.. .: . . : ::.
NP_001 RYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRIAT--VQHEF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 MHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSR---SSNMLTPYDYSSVMHYGRL
.:.::::::..:.::: :.:. :..:: : : :: :... .::::.:::::..
NP_001 LHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 AFSRRGLPTITPLWAPSVH-IGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHAHSTGR
::. :::. . :::: ..: ::. .. :::.:: :
NP_001 AFQNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
NP_001 MIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAVLESRTLYP
280 290 300 310 320 330
>>NP_005916 (OMIM: 600389) meprin A subunit beta isoform (701 aa)
initn: 462 init1: 186 opt: 464 Z-score: 312.9 bits: 67.7 E(85289): 1.1e-10
Smith-Waterman score: 501; 37.8% identity (63.8% similar) in 254 aa overlap (41-284:20-258)
20 30 40 50 60
pF1KE5 VLGLLSLPGVILGAPLASSCAGACGTSFPDGL-TPEGTQASG--DKDIPAINQGLILEET
:: :::. ...: :.:: ::.:: :.
NP_005 MDLWNLSWFLFLDALLVISGLATPENFDVDGGMDQDIFDINEGLGLD--
10 20 30 40
70 80 90 100 110 120
pF1KE5 PESSFLIEGDII--RPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALA
:.:::: : . . . . .:: .:..: .. . .. :::.:.
NP_005 -----LFEGDIRLDRAQIRNSIIGEKYRWPH------TIPYVLEDSLEMNAKGVILNAFE
50 60 70 80 90
130 140 150 160 170 180
pF1KE5 EFERSTCIRFVTYQDQRDFISIIPMYGCFSSVG-RSGGMQVVSLAPTCLQKGRGIVLHEL
... .::: : . . ..::.. ::.:::: : : : .:.. .: . . : ::.
NP_005 RYRLKTCIDFKPWAGETNYISVFKGSGCWSSVGNRRVGKQELSIGANCDRIAT--VQHEF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 MHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSR---SSNMLTPYDYSSVMHYGRL
.:.::::::..:.::: :.:. :..:: : : :: :... .::::.:::::..
NP_005 LHALGFWHEQSRSDRDDYVRIMWDRILSGREHNFNTYSDDISDSLNVPYDYTSVMHYSKT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 AFSRRGLPTITPLWAPSVH-IGQRWNLSASDITRVLQLYGCSPSGPRPRGRGSHAHSTGR
::. :::. . :::: ..: ::. .. :::.:: :
NP_005 AFQNGTEPTIVTRISDFEDVIGQRMDFSDSDLLKLNQLYNCSSSLSFMDSCSFELENVCG
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
NP_005 MIQSSGDNADWQRVSQVPRGPESDHSNMGQCQGSGFFMHFDSSSVNVGATAVLESRTLYP
280 290 300 310 320 330
>>XP_011542919 (OMIM: 112264,614856) PREDICTED: bone mor (622 aa)
initn: 398 init1: 245 opt: 446 Z-score: 302.2 bits: 65.5 E(85289): 4.3e-10
Smith-Waterman score: 449; 38.1% identity (64.1% similar) in 231 aa overlap (94-300:130-351)
70 80 90 100 110 120
pF1KE5 LEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEA
:: .::. ::...... .: :. .:
XP_011 TNGQPQRGACGRWRGRSRSRRAATSRPERVWP---DGVI--PFVIGGNFTGSQRAVFRQA
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 LAEFERSTCIRFVTYQDQRDFISII--PMYGCFSSVGR-SGGMQVVSLAPTCLQKGRGIV
. ..:. ::. :. :. ..: . : :: : ::: .:: :..:.. .: . :::
XP_011 MRHWEKHTCVTFLERTDEDSYIVFTYRPC-GCCSYVGRRGGGPQAISIGKNCDK--FGIV
160 170 180 190 200 210
190 200 210 220 230
pF1KE5 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLT---PYDYSSVMH
.::: ::.:::::::: ::::.. . ..: :: : ::.: . ... . ::..:.::
XP_011 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH
220 230 240 250 260 270
240 250 260 270 280
pF1KE5 YGRLAFSRRG--LPTITPLW-APSVH--IGQRWNLSASDITRVLQLYGCSPSG-------
:.: .::: : : ::.: . . .:. :::: :: .::... .:: : :
XP_011 YARNTFSR-GIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDST
280 290 300 310 320 330
290 300 310 320 330
pF1KE5 -----PR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGP
:. : : ..: : . :
XP_011 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA
340 350 360 370 380 390
>>XP_016869227 (OMIM: 112264,614856) PREDICTED: bone mor (717 aa)
initn: 398 init1: 245 opt: 446 Z-score: 301.3 bits: 65.6 E(85289): 4.8e-10
Smith-Waterman score: 449; 38.1% identity (64.1% similar) in 231 aa overlap (94-300:130-351)
70 80 90 100 110 120
pF1KE5 LEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEA
:: .::. ::...... .: :. .:
XP_016 TNGQPQRGACGRWRGRSRSRRAATSRPERVWP---DGVI--PFVIGGNFTGSQRAVFRQA
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 LAEFERSTCIRFVTYQDQRDFISII--PMYGCFSSVGR-SGGMQVVSLAPTCLQKGRGIV
. ..:. ::. :. :. ..: . : :: : ::: .:: :..:.. .: . :::
XP_016 MRHWEKHTCVTFLERTDEDSYIVFTYRPC-GCCSYVGRRGGGPQAISIGKNCDK--FGIV
160 170 180 190 200 210
190 200 210 220 230
pF1KE5 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLT---PYDYSSVMH
.::: ::.:::::::: ::::.. . ..: :: : ::.: . ... . ::..:.::
XP_016 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH
220 230 240 250 260 270
240 250 260 270 280
pF1KE5 YGRLAFSRRG--LPTITPLW-APSVH--IGQRWNLSASDITRVLQLYGCSPSG-------
:.: .::: : : ::.: . . .:. :::: :: .::... .:: : :
XP_016 YARNTFSR-GIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDST
280 290 300 310 320 330
290 300 310 320 330
pF1KE5 -----PR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGP
:. : : ..: : . :
XP_016 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA
340 350 360 370 380 390
>>NP_001190 (OMIM: 112264,614856) bone morphogenetic pro (730 aa)
initn: 398 init1: 245 opt: 446 Z-score: 301.2 bits: 65.6 E(85289): 4.9e-10
Smith-Waterman score: 449; 38.1% identity (64.1% similar) in 231 aa overlap (94-300:130-351)
70 80 90 100 110 120
pF1KE5 LEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEA
:: .::. ::...... .: :. .:
NP_001 TNGQPQRGACGRWRGRSRSRRAATSRPERVWP---DGVI--PFVIGGNFTGSQRAVFRQA
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 LAEFERSTCIRFVTYQDQRDFISII--PMYGCFSSVGR-SGGMQVVSLAPTCLQKGRGIV
. ..:. ::. :. :. ..: . : :: : ::: .:: :..:.. .: . :::
NP_001 MRHWEKHTCVTFLERTDEDSYIVFTYRPC-GCCSYVGRRGGGPQAISIGKNCDK--FGIV
160 170 180 190 200 210
190 200 210 220 230
pF1KE5 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSRSSNMLT---PYDYSSVMH
.::: ::.:::::::: ::::.. . ..: :: : ::.: . ... . ::..:.::
NP_001 VHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMH
220 230 240 250 260 270
240 250 260 270 280
pF1KE5 YGRLAFSRRG--LPTITPLW-APSVH--IGQRWNLSASDITRVLQLYGCSPSG-------
:.: .::: : : ::.: . . .:. :::: :: .::... .:: : :
NP_001 YARNTFSR-GIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDST
280 290 300 310 320 330
290 300 310 320 330
pF1KE5 -----PR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGP
:. : : ..: : . :
NP_001 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA
340 350 360 370 380 390
431 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:55:10 2016 done: Tue Nov 8 01:55:11 2016
Total Scan time: 10.240 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]