Result of FASTA (ccds) for
pFN21AE5566
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5566, 439 aa
1>>>pF1KE5566 439 - 439 aa - 439 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2383+/-0.000923; mu= 12.3006+/- 0.056
mean_var=74.4507+/-15.321, 0's: 0 Z-trim(106.2): 20 B-trim: 19 in 2/50
Lambda= 0.148641
statistics sampled from 8829 (8837) to 8829 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.271), width: 16
Scan time: 2.870
The best scores are: opt bits E(32554)
CCDS55001.1 UBR2 gene_id:23304|Hs108|chr6 ( 439) 3002 653.3 1.4e-187
CCDS4870.1 UBR2 gene_id:23304|Hs108|chr6 (1755) 2846 619.9 6e-177
CCDS10091.1 UBR1 gene_id:197131|Hs108|chr15 (1749) 1433 316.9 9.8e-86
CCDS2238.2 UBR3 gene_id:130507|Hs108|chr2 (1888) 306 75.3 5.9e-13
>>CCDS55001.1 UBR2 gene_id:23304|Hs108|chr6 (439 aa)
initn: 3002 init1: 3002 opt: 3002 Z-score: 3481.1 bits: 653.3 E(32554): 1.4e-187
Smith-Waterman score: 3002; 100.0% identity (100.0% similar) in 439 aa overlap (1-439:1-439)
10 20 30 40 50 60
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
370 380 390 400 410 420
430
pF1KE5 IFTVPSLFSISAGRSGSPL
:::::::::::::::::::
CCDS55 IFTVPSLFSISAGRSGSPL
430
>>CCDS4870.1 UBR2 gene_id:23304|Hs108|chr6 (1755 aa)
initn: 2846 init1: 2846 opt: 2846 Z-score: 3290.3 bits: 619.9 E(32554): 6e-177
Smith-Waterman score: 2846; 96.7% identity (98.8% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 EDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 CVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 VHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 QVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTKPLKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 QVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLSDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLSVQ
::::::::::::::::::::::::::::::::::::..:: :.. :::.: ::. ::::
CCDS48 KLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYQQLQRDFMEDDHERAVSVTALSVQ
370 380 390 400 410 420
430
pF1KE5 IFTVPSLFSISAGRSGSPL
.::.:.:
CCDS48 FFTAPTLARMLITEENLMSIIIKTFMDHLRHRDAQGRFQFERYTALQAFKFRRVQSLILD
430 440 450 460 470 480
>>CCDS10091.1 UBR1 gene_id:197131|Hs108|chr15 (1749 aa)
initn: 1332 init1: 870 opt: 1433 Z-score: 1652.7 bits: 316.9 E(32554): 9.8e-86
Smith-Waterman score: 1433; 48.8% identity (78.9% similar) in 412 aa overlap (17-427:18-427)
10 20 30 40 50
pF1KE5 MASELEPEVQAIDRSLLECSAEEIAGKWLQATDLTREVYQHLAHYVPKIYCRGPNPFPQ
: . ...:. : : .:. .:::. ::.:: .: .
CCDS10 MADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 KEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDP
:.. .: .. :.:::: :::: . . ::.... .::::::: :: ::::::::.::
CCDS10 KQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGA-FQLCGRVFKSGETTYSCRDCAIDP
70 80 90 100 110
120 130 140 150 160 170
pF1KE5 TCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHELNTSEIEEEEDP
::::::.:: :.:..:::.: :: :::::::::::::: ::.: .:: . . .: .
CCDS10 TCVLCMDCFQDSVHKNHRYKMHTSTGGGFCDCGDTEAWKTGPFCVNHEPGRAGTIKE-NS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 LVHLSEDVIARTYNIFAITFRYAVEILTWEKESELPADLEMVEKSDTYYCMLFNDEVHTY
:.:.::... .:: ...:.::. ::.:.::: .:.. ::.. :::.::::: :.:
CCDS10 RCPLNEEVIVQARKIFPSVIKYVVEMTIWEEEKELPPELQIREKNERYYCVLFNDEHHSY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 EQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTK-PL
..:::.::.:..: :: .:..:..:::.:. : . :..:: : .. .. ::
CCDS10 DHVIYSLQRALDCELAEAQLHTTAIDKEGRRAVKAGAYAACQEAKEDIKSHSENVSQHPL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 KVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDGLRRILCQVGLQEGPDGENSSLVDRLMLS
.:.:.:: :.:::.:.:.: ::...:..::. .:.:.::. :.: ::.:: :..::::
CCDS10 HVEVLHSEIMAHQKFALRLGSWMNKIMSYSSDFRQIFCQACLREEPDSENPCLISRLMLW
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 DSKLWKGARSVYHQLFMSSLLMDLKYKKLFAVRFAKNYERLQSDYVTDDHDREFSVADLS
:.::.::::.. :.:..::..:...::::::..:.: :..::..:..::::: .:.. ::
CCDS10 DAKLYKGARKILHELIFSSFFMEMEYKKLFAMEFVKYYKQLQKEYISDDHDRSISITALS
360 370 380 390 400 410
420 430
pF1KE5 VQIFTVPSLFSISAGRSGSPL
::.::::.:
CCDS10 VQMFTVPTLARHLIEEQNVISVITETLLEVLPEYLDRNNKFNFQGYSQDKLGRVYAVICD
420 430 440 450 460 470
>>CCDS2238.2 UBR3 gene_id:130507|Hs108|chr2 (1888 aa)
initn: 257 init1: 257 opt: 306 Z-score: 346.0 bits: 75.3 E(32554): 5.9e-13
Smith-Waterman score: 308; 24.7% identity (54.2% similar) in 373 aa overlap (73-423:91-452)
50 60 70 80 90
pF1KE5 AHYVPKIYCRGPNPFPQKEDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANK---PSHLC
.:: : . :. .. : . :. ::
CCDS22 AERPLAAAAGGEDAAAAGGGGGPGAAEEEALEWCKCLLAGGGGYDEFCAAVRAYDPAALC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 GRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKE
: :. .. .: :: :...: :: ::: . : : . : : .:: :::::... .:
CCDS22 GLVWTANFVAYRCRTCGISPCMSLCAECFHQGDHTGHDFNMFRSQAGGACDCGDSNVMRE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 GPYCQKHEL-NTSEIEEEEDPLVHLSEDVIARTYNIFAITFR--YAVEILTWEKESELPA
. .:..:.. ..:.: :. .:: :. : . .: : .:..:
CCDS22 SGFCKRHQIKSSSNIPCVPKDLLMMSEFVLPRFIFCLIQYLREGYNEPAADGPSEKDLNK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 DLEMVEKSDTYYCML--FNDEVHTY-EQVIYTLQKAVNCTQKEAIGFATTVDRDGRR---
:...: . .. : .. ... ::. . :. . :. ..: . : .. ..
CCDS22 VLQLLEPQISFLEDLTKMGGAMRSVLTQVLTNQQNYKDLTS--GLGENACVKKSHEKYLI
250 260 270 280 290
280 290 300 310 320 330
pF1KE5 SVRYGDFQYCEQAKSVIVRNTSRQTKPLKVQVMHSSIVAHQNFGLKLLSWLGSIIGYSDG
... . . : :. :.. : :. : :: . : : ..: : . : :.:
CCDS22 ALKSSGLTYPEDKLVYGVQEPSAGTSSLAVQ---GFIGATGTLGQVDSSDEDDQDG-SQG
300 310 320 330 340 350
340 350 360 370 380
pF1KE5 LRRILCQVGLQEGPDGENSSLVDRL----MLSDSKLWKGARSVYHQL--FMSSLLMDLKY
: . .: :. : ...:..: : .: . .: ... :. ..: : .:
CCDS22 LGK-RKRVKLSSGT--KDQSIMDVLKHKSFLEELLFWTIKYEFPQKMVTFLLNMLPDQEY
360 370 380 390 400 410
390 400 410 420 430
pF1KE5 KKLFAVRFAKNY----ERLQSDYVTDDHDREFSVADLSVQIFTVPSLFSISAGRSGSPL
: :. :...: . :.... .: . . .. .:::.:.
CCDS22 KVAFTKTFVQHYAFIMKTLKKSHESDTMSNR--IVHISVQLFSNEELARQVTEECQLLDI
420 430 440 450 460
CCDS22 MVTVLLYMMESCLIKSELQDEENSLHVVVNCGEALLKNNTYWPLVSDFINILSHQSVAKR
470 480 490 500 510 520
439 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:53:48 2016 done: Tue Nov 8 01:53:49 2016
Total Scan time: 2.870 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]