Result of FASTA (omim) for
pFN21AE5564
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5564, 424 aa
1>>>pF1KE5564 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8799+/-0.000394; mu= 20.5575+/- 0.024
mean_var=80.2918+/-16.973, 0's: 0 Z-trim(112.8): 78 B-trim: 53 in 1/52
Lambda= 0.143133
statistics sampled from 21840 (21917) to 21840 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.257), width: 16
Scan time: 6.570
The best scores are: opt bits E(85289)
NP_002546 (OMIM: 114480,211980,268210,602631) solu ( 424) 2714 570.3 3.1e-162
NP_899056 (OMIM: 114480,211980,268210,602631) solu ( 424) 2714 570.3 3.1e-162
NP_001302430 (OMIM: 114480,211980,268210,602631) s ( 509) 2714 570.4 3.6e-162
XP_011518444 (OMIM: 114480,211980,268210,602631) P ( 379) 1837 389.2 9.5e-108
XP_011518443 (OMIM: 114480,211980,268210,602631) P ( 386) 1837 389.2 9.6e-108
NP_001302431 (OMIM: 114480,211980,268210,602631) s ( 326) 1605 341.2 2.3e-93
NP_001139541 (OMIM: 610977) major facilitator supe ( 455) 237 58.9 3.1e-08
NP_001111 (OMIM: 610977) major facilitator superfa ( 455) 237 58.9 3.1e-08
NP_439896 (OMIM: 613361) MFS-type transporter SLC1 ( 456) 231 57.6 7.3e-08
XP_005247984 (OMIM: 610977) PREDICTED: major facil ( 480) 228 57.0 1.2e-07
XP_016865725 (OMIM: 613361) PREDICTED: MFS-type tr ( 409) 205 52.2 2.8e-06
NP_001289572 (OMIM: 612107,616063) solute carrier ( 430) 184 47.9 5.9e-05
NP_071365 (OMIM: 612107,616063) solute carrier fam ( 436) 184 47.9 5.9e-05
>>NP_002546 (OMIM: 114480,211980,268210,602631) solute c (424 aa)
initn: 2714 init1: 2714 opt: 2714 Z-score: 3033.5 bits: 570.3 E(85289): 3.1e-162
Smith-Waterman score: 2714; 99.8% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KE5 MQGARAPRDQGQSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIA
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MQGARAPRDQGRSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 FASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 QCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 PRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 HFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 DTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRK
370 380 390 400 410 420
pF1KE5 DKVR
::::
NP_002 DKVR
>>NP_899056 (OMIM: 114480,211980,268210,602631) solute c (424 aa)
initn: 2714 init1: 2714 opt: 2714 Z-score: 3033.5 bits: 570.3 E(85289): 3.1e-162
Smith-Waterman score: 2714; 99.8% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KE5 MQGARAPRDQGQSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIA
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 MQGARAPRDQGRSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 FGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 FASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 FASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 QCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 QCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 PRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 PRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 HFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 HFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 DTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_899 DTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRK
370 380 390 400 410 420
pF1KE5 DKVR
::::
NP_899 DKVR
>>NP_001302430 (OMIM: 114480,211980,268210,602631) solut (509 aa)
initn: 2714 init1: 2714 opt: 2714 Z-score: 3032.5 bits: 570.4 E(85289): 3.6e-162
Smith-Waterman score: 2714; 99.8% identity (100.0% similar) in 424 aa overlap (1-424:86-509)
10 20 30
pF1KE5 MQGARAPRDQGQSPGRMSALGRSSVILLTY
:::::::::::.::::::::::::::::::
NP_001 PLPGSTGLLPPAPPASCLDLSWVSLLRLSRMQGARAPRDQGRSPGRMSALGRSSVILLTY
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 VLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARA
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE5 ALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE5 AALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAK
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE5 TDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQ
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE5 LEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFH
360 370 380 390 400 410
340 350 360 370 380 390
pF1KE5 FCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLYRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLYRS
420 430 440 450 460 470
400 410 420
pF1KE5 FGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
::::::::::::::::::::::::::::::::::
NP_001 FGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
480 490 500
>>XP_011518444 (OMIM: 114480,211980,268210,602631) PREDI (379 aa)
initn: 1837 init1: 1837 opt: 1837 Z-score: 2055.4 bits: 389.2 E(85289): 9.5e-108
Smith-Waterman score: 1837; 99.7% identity (100.0% similar) in 288 aa overlap (1-288:86-373)
10 20 30
pF1KE5 MQGARAPRDQGQSPGRMSALGRSSVILLTY
:::::::::::.::::::::::::::::::
XP_011 PLPGSTGLLPPAPPASCLDLSWVSLLRLSRMQGARAPRDQGRSPGRMSALGRSSVILLTY
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 VLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARA
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE5 ALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE5 AALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAK
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE5 TDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQ
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE5 LEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFH
::::::::::::::::::
XP_011 LEAAQAGYLMSFFGLLQMGPWQMR
360 370
>>XP_011518443 (OMIM: 114480,211980,268210,602631) PREDI (386 aa)
initn: 1837 init1: 1837 opt: 1837 Z-score: 2055.3 bits: 389.2 E(85289): 9.6e-108
Smith-Waterman score: 1837; 99.7% identity (100.0% similar) in 288 aa overlap (1-288:86-373)
10 20 30
pF1KE5 MQGARAPRDQGQSPGRMSALGRSSVILLTY
:::::::::::.::::::::::::::::::
XP_011 PLPGSTGLLPPAPPASCLDLSWVSLLRLSRMQGARAPRDQGRSPGRMSALGRSSVILLTY
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 VLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARA
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE5 ALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERP
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE5 AALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAK
240 250 260 270 280 290
220 230 240 250 260 270
pF1KE5 TDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQ
300 310 320 330 340 350
280 290 300 310 320 330
pF1KE5 LEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFH
::::::::::::::::::
XP_011 LEAAQAGYLMSFFGLLQMAKVPALQGPWQMR
360 370 380
>>NP_001302431 (OMIM: 114480,211980,268210,602631) solut (326 aa)
initn: 2087 init1: 1582 opt: 1605 Z-score: 1797.3 bits: 341.2 E(85289): 2.3e-93
Smith-Waterman score: 1895; 76.7% identity (76.9% similar) in 424 aa overlap (1-424:1-326)
10 20 30 40 50 60
pF1KE5 MQGARAPRDQGQSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIA
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQGARAPRDQGRSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLL
:::::::::::::::::::::
NP_001 FGYLQTTFGVLQLLGGPVFGR---------------------------------------
70 80
130 140 150 160 170 180
pF1KE5 FASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGI
:
NP_001 -----------------------------------------------------------I
190 200 210 220 230 240
pF1KE5 QCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDV
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE5 PRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSS
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE5 HFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTS
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE5 DTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRK
270 280 290 300 310 320
pF1KE5 DKVR
::::
NP_001 DKVR
>>NP_001139541 (OMIM: 610977) major facilitator superfam (455 aa)
initn: 84 init1: 58 opt: 237 Z-score: 268.8 bits: 58.9 E(85289): 3.1e-08
Smith-Waterman score: 262; 25.3% identity (55.3% similar) in 387 aa overlap (57-422:84-453)
30 40 50 60 70 80
pF1KE5 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
.:. :: : ..:.:::.: .:. : .:
NP_001 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE5 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
NP_001 LGRRPVMLLCLMGVATSYAVWATSRSFA-----AFLASRLIGGISKGNVSLSTAIVADLG
120 130 140 150 160
150 160 170 180 190 200
pF1KE5 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
NP_001 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
170 180 190 200 210 220
210 220 230 240 250
pF1KE5 STKGAKTDAQAP-LPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--F
. : .:: . : : .. :: . .:::. : : ...: :: :
NP_001 TLPLEK---RAPSIALGFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYF
230 240 250 260 270 280
260 270 280 290 300
pF1KE5 MVMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVL-
. .: :... . ::. . : : .. ..:: . . :: .. : . ::
NP_001 LYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRI--HPGGEVAA
290 300 310 320 330
310 320 330 340 350 360
pF1KE5 LRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVT--DSMLIKAVSTSDTGTM
.. ..:... . : ..: :. . : . :..:. . :: .:.. : .. ::.
NP_001 VKRALLLLVPAFLLIGWGRSLPVLGLGL--LLYSFAAAVVVPCLSSVVAGYGSPGQKGTV
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE5 LGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
.: :. : :. :: :.. .: :. . . .. : ...: . .: . :
NP_001 MGTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
400 410 420 430 440 450
>>NP_001111 (OMIM: 610977) major facilitator superfamily (455 aa)
initn: 84 init1: 58 opt: 237 Z-score: 268.8 bits: 58.9 E(85289): 3.1e-08
Smith-Waterman score: 262; 25.3% identity (55.3% similar) in 387 aa overlap (57-422:84-453)
30 40 50 60 70 80
pF1KE5 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
.:. :: : ..:.:::.: .:. : .:
NP_001 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE5 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
NP_001 LGRRPVMLLCLMGVATSYAVWATSRSFA-----AFLASRLIGGISKGNVSLSTAIVADLG
120 130 140 150 160
150 160 170 180 190 200
pF1KE5 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
NP_001 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
170 180 190 200 210 220
210 220 230 240 250
pF1KE5 STKGAKTDAQAP-LPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--F
. : .:: . : : .. :: . .:::. : : ...: :: :
NP_001 TLPLEK---RAPSIALGFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYF
230 240 250 260 270 280
260 270 280 290 300
pF1KE5 MVMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVL-
. .: :... . ::. . : : .. ..:: . . :: .. : . ::
NP_001 LYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRI--HPGGEVAA
290 300 310 320 330
310 320 330 340 350 360
pF1KE5 LRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVT--DSMLIKAVSTSDTGTM
.. ..:... . : ..: :. . : . :..:. . :: .:.. : .. ::.
NP_001 VKRALLLLVPAFLLIGWGRSLPVLGLGL--LLYSFAAAVVVPCLSSVVAGYGSPGQKGTV
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE5 LGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
.: :. : :. :: :.. .: :. . . .. : ...: . .: . :
NP_001 MGTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
400 410 420 430 440 450
>>NP_439896 (OMIM: 613361) MFS-type transporter SLC18B1 (456 aa)
initn: 208 init1: 96 opt: 231 Z-score: 262.1 bits: 57.6 E(85289): 7.3e-08
Smith-Waterman score: 261; 23.9% identity (56.7% similar) in 427 aa overlap (1-400:7-411)
10 20 30 40
pF1KE5 MQGARAPRDQ------GQSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIV-
..: ::: . :..:: .: : .:..: . ::. .: .::.
NP_439 MEALGDLEGPRAPGGDDPAGSAGETPGWLS---REQVFVL--ISAASVNLGSMMCYSILG
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 PYLSR---KLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYL
:.. . : : .. .:.. :....::.. ::: . . ::. .. ..... .. .
NP_439 PFFPKEAEKKGASNTIIGMIFGCFALFELLASLVFGNYLVHIGAKFMFVAGMFVSGGVTI
60 70 80 90 100 110
110 120 130 140 150
pF1KE5 LLAAASS-PALPG-VYLLFASRLPGALMHTLPAAQMVITDLSA---PEERPAALGRLGLC
:... . : : . . : :. :. .. ::. . ... : :.. ..:: :
NP_439 LFGVLDRVPDGPVFIAMCFLVRVMDAV--SFAAAMTASSSILAKAFPNNVATVLGSLETF
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE5 FGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPG
:.:.::: .:: : ...: . : :. . ..:: . :.. .: . . : .
NP_439 SGLGLILGPPVGGFLYQSFGYEVPFIVLGCVVLLMVPLNMYILPNYESDPGEHSFWKLIA
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE5 GPRASV--FDLKAIASLLRLPDVPRIFLVKVASNCPTG------LFMVMFSIISMDFFQL
:.... : .....: . . : ..: : :.: : :.. :: .: :
NP_439 LPKVGLIAFVINSLSSCFGFLDPTLSLFVLEKFNLPAGYVGLVFLGMALSYAISSPLFGL
240 250 260 270 280 290
280 290 300 310 320
pF1KE5 EAAQAGYLMSFFGLL-QMVTQG--LVIGQLSS-HFSEEVLLRASVLVFIVVGLAMAWMSS
. . : ... .. ...: : ...: . :.. .. : ::...: ::. : ::
NP_439 LSDKRPPLRKWLLVFGNLITAGCYMLLGPVPILHIKSQLWLL--VLILVVSGLS-AGMSI
300 310 320 330 340 350
330 340 350 360 370 380
pF1KE5 VFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLL
. : : . :. . .. . ...:: : . :: ... . .:::.::.:
NP_439 IPTF----PEI------LSCAHENGFEEGLST--LGLVSGLFSAMWSIGAFMGPTLGGFL
360 370 380 390
390 400 410 420
pF1KE5 YRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
:...: . .:
NP_439 YEKIGFEWAAAIQGLWALISGLAMGLFYLLEYSRRKRSKSQNILSTEEERTTLLPNET
400 410 420 430 440 450
>>XP_005247984 (OMIM: 610977) PREDICTED: major facilitat (480 aa)
initn: 84 init1: 58 opt: 228 Z-score: 258.5 bits: 57.0 E(85289): 1.2e-07
Smith-Waterman score: 253; 26.4% identity (55.7% similar) in 348 aa overlap (57-383:84-414)
30 40 50 60 70 80
pF1KE5 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
.:. :: : ..:.:::.: .:. : .:
XP_005 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE5 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
XP_005 LGRRPVMLLCLMGVATSYAVWATSRSFAA-----FLASRLIGGISKGNVSLSTAIVADLG
120 130 140 150 160
150 160 170 180 190 200
pF1KE5 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
XP_005 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
170 180 190 200 210 220
210 220 230 240 250
pF1KE5 STKGAKTDAQAP-LPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--F
. : .:: . : : .. :: . .:::. : : ...: :: :
XP_005 TLPLEK---RAPSIALGFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYF
230 240 250 260 270 280
260 270 280 290 300
pF1KE5 MVMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVL-
. .: :... . ::. . : : .. ..:: . . :: .. : . ::
XP_005 LYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRI--HPGGEVAA
290 300 310 320 330
310 320 330 340 350 360
pF1KE5 LRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVT--DSMLIKAVSTSDTGTM
.. ..:... . : ..: :. . : . :..:. . :: .:.. : .. ::.
XP_005 VKRALLLLVPAFLLIGWGRSLPVLGLGL--LLYSFAAAVVVPCLSSVVAGYGSPGQKGTV
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE5 LGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
.: :. : :. :: :
XP_005 MGTLRSLGALARAAGPLVAASGEGAGWCWGRLGAKHLPSPPKCQPPRGLGDATVSPQCTG
400 410 420 430 440 450
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:52:20 2016 done: Tue Nov 8 01:52:21 2016
Total Scan time: 6.570 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]