Result of FASTA (omim) for
pFN21AE5563
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5563, 412 aa
1>>>pF1KE5563 412 - 412 aa - 412 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1377+/-0.000417; mu= 13.3049+/- 0.026
mean_var=100.5529+/-20.637, 0's: 0 Z-trim(113.3): 412 B-trim: 456 in 1/54
Lambda= 0.127902
statistics sampled from 22147 (22603) to 22147 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.265), width: 16
Scan time: 8.200
The best scores are: opt bits E(85289)
NP_570897 (OMIM: 602853) receptor-type tyrosine-pr ( 412) 2744 517.2 3e-146
NP_001193945 (OMIM: 602853) receptor-type tyrosine ( 451) 2744 517.2 3.2e-146
NP_001193944 (OMIM: 602853) receptor-type tyrosine ( 545) 2744 517.3 3.7e-146
XP_011536917 (OMIM: 602853) PREDICTED: receptor-ty ( 649) 2744 517.3 4.3e-146
NP_002840 (OMIM: 602853) receptor-type tyrosine-pr ( 657) 2744 517.3 4.3e-146
NP_001265168 (OMIM: 176879) tyrosine-protein phosp ( 509) 1362 262.2 2.1e-69
NP_001035059 (OMIM: 176879) tyrosine-protein phosp ( 533) 1362 262.2 2.1e-69
NP_001265165 (OMIM: 176879) tyrosine-protein phosp ( 533) 1362 262.2 2.1e-69
NP_001265167 (OMIM: 176879) tyrosine-protein phosp ( 541) 1362 262.3 2.2e-69
NP_116170 (OMIM: 176879) tyrosine-protein phosphat ( 565) 1362 262.3 2.2e-69
NP_008837 (OMIM: 176879) tyrosine-protein phosphat ( 565) 1362 262.3 2.2e-69
NP_542155 (OMIM: 176889) tyrosine-protein phosphat ( 399) 1293 249.4 1.2e-65
NP_001186726 (OMIM: 176889) tyrosine-protein phosp ( 434) 1293 249.5 1.2e-65
NP_002823 (OMIM: 176889) tyrosine-protein phosphat ( 465) 1293 249.5 1.3e-65
XP_016857425 (OMIM: 176889) PREDICTED: tyrosine-pr ( 464) 1280 247.1 6.8e-65
XP_016857426 (OMIM: 176889) PREDICTED: tyrosine-pr ( 359) 1276 246.3 9.3e-65
XP_011518713 (OMIM: 176879) PREDICTED: tyrosine-pr ( 553) 1227 237.3 6.9e-62
XP_011508121 (OMIM: 176889) PREDICTED: tyrosine-pr ( 511) 1175 227.7 5e-59
XP_011508122 (OMIM: 176889) PREDICTED: tyrosine-pr ( 400) 1172 227.1 6.1e-59
XP_016857424 (OMIM: 176889) PREDICTED: tyrosine-pr ( 510) 1162 225.3 2.6e-58
XP_011508124 (OMIM: 176889) PREDICTED: tyrosine-pr ( 354) 1057 205.8 1.3e-52
XP_011508123 (OMIM: 176889) PREDICTED: tyrosine-pr ( 354) 1057 205.8 1.3e-52
XP_016873929 (OMIM: 176879) PREDICTED: tyrosine-pr ( 527) 823 162.8 1.8e-39
XP_016873930 (OMIM: 176879) PREDICTED: tyrosine-pr ( 490) 819 162.0 2.9e-39
XP_016873928 (OMIM: 176879) PREDICTED: tyrosine-pr ( 663) 819 162.1 3.7e-39
XP_016873927 (OMIM: 176879) PREDICTED: tyrosine-pr ( 680) 819 162.1 3.7e-39
XP_016873926 (OMIM: 176879) PREDICTED: tyrosine-pr ( 687) 819 162.1 3.8e-39
XP_016873925 (OMIM: 176879) PREDICTED: tyrosine-pr ( 695) 819 162.1 3.8e-39
XP_016873924 (OMIM: 176879) PREDICTED: tyrosine-pr ( 719) 819 162.1 3.9e-39
XP_016873923 (OMIM: 176879) PREDICTED: tyrosine-pr ( 719) 819 162.1 3.9e-39
XP_011508125 (OMIM: 176889) PREDICTED: tyrosine-pr ( 311) 659 132.4 1.6e-30
XP_011508126 (OMIM: 176889) PREDICTED: tyrosine-pr ( 235) 654 131.4 2.4e-30
NP_109593 (OMIM: 600579,614196) receptor-type tyro ( 377) 636 128.2 3.4e-29
NP_109595 (OMIM: 600579,614196) receptor-type tyro ( 377) 636 128.2 3.4e-29
NP_109594 (OMIM: 600579,614196) receptor-type tyro ( 405) 636 128.2 3.6e-29
NP_109596 (OMIM: 600579,614196) receptor-type tyro ( 405) 636 128.2 3.6e-29
NP_002839 (OMIM: 600579,614196) receptor-type tyro (1188) 636 128.5 8.5e-29
NP_109592 (OMIM: 600579,614196) receptor-type tyro (1216) 636 128.5 8.6e-29
XP_016883102 (OMIM: 608712) PREDICTED: receptor-ty (1436) 637 128.8 8.7e-29
NP_008981 (OMIM: 608712) receptor-type tyrosine-pr (1441) 637 128.8 8.7e-29
XP_016883101 (OMIM: 608712) PREDICTED: receptor-ty (1455) 637 128.8 8.7e-29
NP_573400 (OMIM: 608712) receptor-type tyrosine-pr (1460) 637 128.8 8.8e-29
NP_563578 (OMIM: 151460,608971,609532) receptor-ty (1145) 617 125.0 9.4e-28
XP_006711537 (OMIM: 151460,608971,609532) PREDICTE (1192) 617 125.0 9.7e-28
XP_006711536 (OMIM: 151460,608971,609532) PREDICTE (1240) 617 125.0 1e-27
XP_006711535 (OMIM: 151460,608971,609532) PREDICTE (1258) 617 125.0 1e-27
NP_002829 (OMIM: 151460,608971,609532) receptor-ty (1306) 617 125.1 1e-27
XP_016866637 (OMIM: 602545) PREDICTED: receptor-ty (1368) 615 124.7 1.4e-27
NP_001278913 (OMIM: 602545) receptor-type tyrosine (1439) 615 124.7 1.4e-27
NP_002835 (OMIM: 602545) receptor-type tyrosine-pr (1440) 615 124.7 1.4e-27
>>NP_570897 (OMIM: 602853) receptor-type tyrosine-protei (412 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2746.7 bits: 517.2 E(85289): 3e-146
Smith-Waterman score: 2744; 99.8% identity (100.0% similar) in 412 aa overlap (1-412:1-412)
10 20 30 40 50 60
pF1KE5 MILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSMVQPEQAPKVLNVVVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 MILYRLKERFQLSLRQDKEKNQEIHLSPITLQPALSEAKTVHSMVQPEQAPKVLNVVVDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QGRGAPEIRATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTPREK
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 QGRGAPEIKATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLGNIEPFVSIPTPREK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 VAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEIDIPRHGTKNRYKTIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 PNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMINTVDDFWQMVWQEDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 PVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 PVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIRNLVLKQGSHTQHVK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 HYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 HYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGPVVVHCSAGIGRTGCFIATSIGC
310 320 330 340 350 360
370 380 390 400 410
pF1KE5 QQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 QQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLYESRLSAETVQ
370 380 390 400 410
>>NP_001193945 (OMIM: 602853) receptor-type tyrosine-pro (451 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2746.1 bits: 517.2 E(85289): 3.2e-146
Smith-Waterman score: 2744; 99.8% identity (100.0% similar) in 412 aa overlap (1-412:40-451)
10 20 30
pF1KE5 MILYRLKERFQLSLRQDKEKNQEIHLSPIT
::::::::::::::::::::::::::::::
NP_001 QHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPIT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQE
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_001 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
370 380 390 400 410 420
400 410
pF1KE5 QYEFVHHALCLYESRLSAETVQ
::::::::::::::::::::::
NP_001 QYEFVHHALCLYESRLSAETVQ
430 440 450
>>NP_001193944 (OMIM: 602853) receptor-type tyrosine-pro (545 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2745.0 bits: 517.3 E(85289): 3.7e-146
Smith-Waterman score: 2744; 99.8% identity (100.0% similar) in 412 aa overlap (1-412:134-545)
10 20 30
pF1KE5 MILYRLKERFQLSLRQDKEKNQEIHLSPIT
::::::::::::::::::::::::::::::
NP_001 QHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPIT
110 120 130 140 150 160
40 50 60 70 80 90
pF1KE5 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQE
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_001 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQE
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE5 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE5 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
290 300 310 320 330 340
220 230 240 250 260 270
pF1KE5 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
350 360 370 380 390 400
280 290 300 310 320 330
pF1KE5 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
410 420 430 440 450 460
340 350 360 370 380 390
pF1KE5 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
470 480 490 500 510 520
400 410
pF1KE5 QYEFVHHALCLYESRLSAETVQ
::::::::::::::::::::::
NP_001 QYEFVHHALCLYESRLSAETVQ
530 540
>>XP_011536917 (OMIM: 602853) PREDICTED: receptor-type t (649 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2743.9 bits: 517.3 E(85289): 4.3e-146
Smith-Waterman score: 2744; 99.8% identity (100.0% similar) in 412 aa overlap (1-412:238-649)
10 20 30
pF1KE5 MILYRLKERFQLSLRQDKEKNQEIHLSPIT
::::::::::::::::::::::::::::::
XP_011 QHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPIT
210 220 230 240 250 260
40 50 60 70 80 90
pF1KE5 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQE
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
XP_011 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQE
270 280 290 300 310 320
100 110 120 130 140 150
pF1KE5 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
330 340 350 360 370 380
160 170 180 190 200 210
pF1KE5 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
390 400 410 420 430 440
220 230 240 250 260 270
pF1KE5 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
450 460 470 480 490 500
280 290 300 310 320 330
pF1KE5 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
510 520 530 540 550 560
340 350 360 370 380 390
pF1KE5 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
570 580 590 600 610 620
400 410
pF1KE5 QYEFVHHALCLYESRLSAETVQ
::::::::::::::::::::::
XP_011 QYEFVHHALCLYESRLSAETVQ
630 640
>>NP_002840 (OMIM: 602853) receptor-type tyrosine-protei (657 aa)
initn: 2744 init1: 2744 opt: 2744 Z-score: 2743.8 bits: 517.3 E(85289): 4.3e-146
Smith-Waterman score: 2744; 99.8% identity (100.0% similar) in 412 aa overlap (1-412:246-657)
10 20 30
pF1KE5 MILYRLKERFQLSLRQDKEKNQEIHLSPIT
::::::::::::::::::::::::::::::
NP_002 QHEADKIWSKEGFYAVVIFLSIFVIIVTCLMILYRLKERFQLSLRQDKEKNQEIHLSPIT
220 230 240 250 260 270
40 50 60 70 80 90
pF1KE5 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQE
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_002 LQPALSEAKTVHSMVQPEQAPKVLNVVVDPQGRGAPEIKATTATSVCPSPFKMKPIGLQE
280 290 300 310 320 330
100 110 120 130 140 150
pF1KE5 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RRGSNVSLTLDMSSLGNIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQS
340 350 360 370 380 390
160 170 180 190 200 210
pF1KE5 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EFMEIPMNFVDPKEIDIPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGY
400 410 420 430 440 450
220 230 240 250 260 270
pF1KE5 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGKEKAFIATQGPMINTVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKV
460 470 480 490 500 510
280 290 300 310 320 330
pF1KE5 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVLVISVNECDNYTIRNLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDR
520 530 540 550 560 570
340 350 360 370 380 390
pF1KE5 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LASQGRGPVVVHCSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSE
580 590 600 610 620 630
400 410
pF1KE5 QYEFVHHALCLYESRLSAETVQ
::::::::::::::::::::::
NP_002 QYEFVHHALCLYESRLSAETVQ
640 650
>>NP_001265168 (OMIM: 176879) tyrosine-protein phosphata (509 aa)
initn: 1316 init1: 870 opt: 1362 Z-score: 1367.2 bits: 262.2 E(85289): 2.1e-69
Smith-Waterman score: 1362; 60.1% identity (80.2% similar) in 338 aa overlap (78-410:173-507)
50 60 70 80 90 100
pF1KE5 EQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLG-
:. . .: .:::::::::::::::: . :
NP_001 EKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGC
150 160 170 180 190 200
110 120 130 140 150 160
pF1KE5 NIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEID
: : : . .:::. : ::: ::::.: .:.. . . :::.::.::::::::::: :
NP_001 NEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYD
210 220 230 240 250 260
170 180 190 200 210 220
pF1KE5 IPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMIN
:: ::::::::::: ::::: . : ::.::::::::::.:.::..::::::...
NP_001 IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS
270 280 290 300 310 320
230 240 250 260 270 280
pF1KE5 TVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIR
:: :::.::::: .:.:::::...: ::::. ::::.. : ::. : .: . ..: .:
NP_001 TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLR
330 340 350 360 370 380
290 300 310 320 330 340
pF1KE5 NLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGP----VVVH
. ::.:.. . .::::.:::::.:::: : :::.:. .::: :.: .:: ..::
NP_001 LISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE---AAQQEGPHCAPIIVH
390 400 410 420 430
350 360 370 380 390 400
pF1KE5 CSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLY
:::::::::::::::: ::::..::::: :. .::::.:::::.:: :::.::::.. ::
NP_001 CSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY
440 450 460 470 480 490
410
pF1KE5 ESRLSAETVQ
:..:: ..
NP_001 EKQLSHQSPE
500
>>NP_001035059 (OMIM: 176879) tyrosine-protein phosphata (533 aa)
initn: 1316 init1: 870 opt: 1362 Z-score: 1366.9 bits: 262.2 E(85289): 2.1e-69
Smith-Waterman score: 1362; 60.1% identity (80.2% similar) in 338 aa overlap (78-410:197-531)
50 60 70 80 90 100
pF1KE5 EQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLG-
:. . .: .:::::::::::::::: . :
NP_001 EKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGC
170 180 190 200 210 220
110 120 130 140 150 160
pF1KE5 NIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEID
: : : . .:::. : ::: ::::.: .:.. . . :::.::.::::::::::: :
NP_001 NEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYD
230 240 250 260 270 280
170 180 190 200 210 220
pF1KE5 IPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMIN
:: ::::::::::: ::::: . : ::.::::::::::.:.::..::::::...
NP_001 IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS
290 300 310 320 330 340
230 240 250 260 270 280
pF1KE5 TVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIR
:: :::.::::: .:.:::::...: ::::. ::::.. : ::. : .: . ..: .:
NP_001 TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLR
350 360 370 380 390 400
290 300 310 320 330 340
pF1KE5 NLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGP----VVVH
. ::.:.. . .::::.:::::.:::: : :::.:. .::: :.: .:: ..::
NP_001 LISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE---AAQQEGPHCAPIIVH
410 420 430 440 450 460
350 360 370 380 390 400
pF1KE5 CSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLY
:::::::::::::::: ::::..::::: :. .::::.:::::.:: :::.::::.. ::
NP_001 CSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY
470 480 490 500 510 520
410
pF1KE5 ESRLSAETVQ
:..:: ..
NP_001 EKQLSHQSPE
530
>>NP_001265165 (OMIM: 176879) tyrosine-protein phosphata (533 aa)
initn: 1316 init1: 870 opt: 1362 Z-score: 1366.9 bits: 262.2 E(85289): 2.1e-69
Smith-Waterman score: 1362; 60.1% identity (80.2% similar) in 338 aa overlap (78-410:197-531)
50 60 70 80 90 100
pF1KE5 EQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLG-
:. . .: .:::::::::::::::: . :
NP_001 EKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGC
170 180 190 200 210 220
110 120 130 140 150 160
pF1KE5 NIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEID
: : : . .:::. : ::: ::::.: .:.. . . :::.::.::::::::::: :
NP_001 NEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYD
230 240 250 260 270 280
170 180 190 200 210 220
pF1KE5 IPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMIN
:: ::::::::::: ::::: . : ::.::::::::::.:.::..::::::...
NP_001 IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS
290 300 310 320 330 340
230 240 250 260 270 280
pF1KE5 TVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIR
:: :::.::::: .:.:::::...: ::::. ::::.. : ::. : .: . ..: .:
NP_001 TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLR
350 360 370 380 390 400
290 300 310 320 330 340
pF1KE5 NLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGP----VVVH
. ::.:.. . .::::.:::::.:::: : :::.:. .::: :.: .:: ..::
NP_001 LISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE---AAQQEGPHCAPIIVH
410 420 430 440 450 460
350 360 370 380 390 400
pF1KE5 CSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLY
:::::::::::::::: ::::..::::: :. .::::.:::::.:: :::.::::.. ::
NP_001 CSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY
470 480 490 500 510 520
410
pF1KE5 ESRLSAETVQ
:..:: ..
NP_001 EKQLSHQSPE
530
>>NP_001265167 (OMIM: 176879) tyrosine-protein phosphata (541 aa)
initn: 1316 init1: 870 opt: 1362 Z-score: 1366.8 bits: 262.3 E(85289): 2.2e-69
Smith-Waterman score: 1362; 60.1% identity (80.2% similar) in 338 aa overlap (78-410:205-539)
50 60 70 80 90 100
pF1KE5 EQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLG-
:. . .: .:::::::::::::::: . :
NP_001 EKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGC
180 190 200 210 220 230
110 120 130 140 150 160
pF1KE5 NIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEID
: : : . .:::. : ::: ::::.: .:.. . . :::.::.::::::::::: :
NP_001 NEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYD
240 250 260 270 280 290
170 180 190 200 210 220
pF1KE5 IPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMIN
:: ::::::::::: ::::: . : ::.::::::::::.:.::..::::::...
NP_001 IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS
300 310 320 330 340 350
230 240 250 260 270 280
pF1KE5 TVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIR
:: :::.::::: .:.:::::...: ::::. ::::.. : ::. : .: . ..: .:
NP_001 TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLR
360 370 380 390 400 410
290 300 310 320 330 340
pF1KE5 NLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGP----VVVH
. ::.:.. . .::::.:::::.:::: : :::.:. .::: :.: .:: ..::
NP_001 LISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE---AAQQEGPHCAPIIVH
420 430 440 450 460 470
350 360 370 380 390 400
pF1KE5 CSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLY
:::::::::::::::: ::::..::::: :. .::::.:::::.:: :::.::::.. ::
NP_001 CSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY
480 490 500 510 520 530
410
pF1KE5 ESRLSAETVQ
:..:: ..
NP_001 EKQLSHQSPE
540
>>NP_116170 (OMIM: 176879) tyrosine-protein phosphatase (565 aa)
initn: 1316 init1: 870 opt: 1362 Z-score: 1366.5 bits: 262.3 E(85289): 2.2e-69
Smith-Waterman score: 1362; 60.1% identity (80.2% similar) in 338 aa overlap (78-410:229-563)
50 60 70 80 90 100
pF1KE5 EQAPKVLNVVVDPQGRGAPEIRATTATSVCPSPFKMKPIGLQERRGSNVSLTLDMSSLG-
:. . .: .:::::::::::::::: . :
NP_116 EKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGC
200 210 220 230 240 250
110 120 130 140 150 160
pF1KE5 NIEPFVSIPTPREKVAMEYLQSASRILTRSQLRDVVASSHLLQSEFMEIPMNFVDPKEID
: : : . .:::. : ::: ::::.: .:.. . . :::.::.::::::::::: :
NP_116 NEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYD
260 270 280 290 300 310
170 180 190 200 210 220
pF1KE5 IPRHGTKNRYKTILPNPLSRVCLRPKNVTDSLSTYINANYIRGYSGKEKAFIATQGPMIN
:: ::::::::::: ::::: . : ::.::::::::::.:.::..::::::...
NP_116 IPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVS
320 330 340 350 360 370
230 240 250 260 270 280
pF1KE5 TVDDFWQMVWQEDSPVIVMITKLKEKNEKCVLYWPEKRGIYGKVEVLVISVNECDNYTIR
:: :::.::::: .:.:::::...: ::::. ::::.. : ::. : .: . ..: .:
NP_116 TVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLR
380 390 400 410 420 430
290 300 310 320 330 340
pF1KE5 NLVLKQGSHTQHVKHYWYTSWPDHKTPDSAQPLLQLMLDVEEDRLASQGRGP----VVVH
. ::.:.. . .::::.:::::.:::: : :::.:. .::: :.: .:: ..::
NP_116 LISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE---AAQQEGPHCAPIIVH
440 450 460 470 480 490
350 360 370 380 390 400
pF1KE5 CSAGIGRTGCFIATSIGCQQLKEEGVVDALSIVCQLRMDRGGMVQTSEQYEFVHHALCLY
:::::::::::::::: ::::..::::: :. .::::.:::::.:: :::.::::.. ::
NP_116 CSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLY
500 510 520 530 540 550
410
pF1KE5 ESRLSAETVQ
:..:: ..
NP_116 EKQLSHQSPE
560
412 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:50:36 2016 done: Tue Nov 8 04:50:37 2016
Total Scan time: 8.200 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]