Result of FASTA (omim) for
pFN21AE5554
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5554, 429 aa
1>>>pF1KE5554 429 - 429 aa - 429 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0757+/-0.000309; mu= 6.3232+/- 0.019
mean_var=166.8273+/-34.413, 0's: 0 Z-trim(121.7): 18 B-trim: 2168 in 1/57
Lambda= 0.099298
statistics sampled from 38671 (38696) to 38671 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.454), width: 16
Scan time: 9.160
The best scores are: opt bits E(85289)
NP_110403 (OMIM: 606750) Z-DNA-binding protein 1 i ( 429) 2934 431.9 1.6e-120
NP_001153889 (OMIM: 606750) Z-DNA-binding protein ( 428) 2916 429.3 9.3e-120
XP_011527359 (OMIM: 606750) PREDICTED: Z-DNA-bindi ( 405) 2483 367.2 4.2e-101
NP_001153890 (OMIM: 606750) Z-DNA-binding protein ( 354) 2362 349.9 6.2e-96
XP_011527360 (OMIM: 606750) PREDICTED: Z-DNA-bindi ( 357) 1992 296.9 5.7e-80
NP_001153891 (OMIM: 606750) Z-DNA-binding protein ( 248) 1507 227.3 3.5e-59
XP_016883575 (OMIM: 606750) PREDICTED: Z-DNA-bindi ( 245) 1134 173.8 4.2e-43
NP_001310895 (OMIM: 606750) Z-DNA-binding protein ( 173) 935 145.2 1.2e-34
>>NP_110403 (OMIM: 606750) Z-DNA-binding protein 1 isofo (429 aa)
initn: 2934 init1: 2934 opt: 2934 Z-score: 2284.9 bits: 431.9 E(85289): 1.6e-120
Smith-Waterman score: 2934; 99.5% identity (100.0% similar) in 429 aa overlap (1-429:1-429)
10 20 30 40 50 60
pF1KE5 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRFLKDN
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_110 TSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TWGTLVDPWGPQDIHMERSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_110 TWGTLVDPWGPQDIHMEQSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 ASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 ASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 GEDAGRRPADTQSRSHFPRDIGQPITPSHSKLTPKLETMTLGNRSHKAAEGSHYVDEASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_110 GEDAGRRPADTQSRSHFPRDIGQPITPSHSKLTPKLETMTLGNRSHKAAEGSHYVDEASH
370 380 390 400 410 420
pF1KE5 EGSWWGGGI
:::::::::
NP_110 EGSWWGGGI
>>NP_001153889 (OMIM: 606750) Z-DNA-binding protein 1 is (428 aa)
initn: 1811 init1: 1811 opt: 2916 Z-score: 2271.0 bits: 429.3 E(85289): 9.3e-120
Smith-Waterman score: 2916; 99.3% identity (99.8% similar) in 429 aa overlap (1-429:1-428)
10 20 30 40 50 60
pF1KE5 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRFLKDN
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_001 TSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRP-DSGRRAKSASII
130 140 150 160 170
190 200 210 220 230 240
pF1KE5 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 TWGTLVDPWGPQDIHMERSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
NP_001 TWGTLVDPWGPQDIHMEQSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 ASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 GEDAGRRPADTQSRSHFPRDIGQPITPSHSKLTPKLETMTLGNRSHKAAEGSHYVDEASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEDAGRRPADTQSRSHFPRDIGQPITPSHSKLTPKLETMTLGNRSHKAAEGSHYVDEASH
360 370 380 390 400 410
pF1KE5 EGSWWGGGI
:::::::::
NP_001 EGSWWGGGI
420
>>XP_011527359 (OMIM: 606750) PREDICTED: Z-DNA-binding p (405 aa)
initn: 2483 init1: 2483 opt: 2483 Z-score: 1936.1 bits: 367.2 E(85289): 4.2e-101
Smith-Waterman score: 2487; 93.0% identity (94.3% similar) in 402 aa overlap (1-391:1-402)
10 20 30 40 50 60
pF1KE5 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRFLKDN
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_011 TSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TWGTLVDPWGPQDIHMERSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_011 TWGTLVDPWGPQDIHMEQSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 ASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEP
310 320 330 340 350 360
370 380 390 400
pF1KE5 GEDAGRRPAD-------TQSRSHFPRDIGQPI----TPSHSKLTPKLETMTLGNRSHKAA
::::: : : .:: : : .. : :: ::
XP_011 GEDAGPLGAPCTCDTCRTGTRSAFLRTQAMSIWEHGLPSSSKGSL
370 380 390 400
410 420
pF1KE5 EGSHYVDEASHEGSWWGGGI
>>NP_001153890 (OMIM: 606750) Z-DNA-binding protein 1 is (354 aa)
initn: 2362 init1: 2362 opt: 2362 Z-score: 1843.3 bits: 349.9 E(85289): 6.2e-96
Smith-Waterman score: 2362; 99.4% identity (100.0% similar) in 343 aa overlap (87-429:12-354)
60 70 80 90 100 110
pF1KE5 KVSLTSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRF
:.::::::::::::::::::::::::::::
NP_001 MAQAPADPGREAERPQQHAATIPETPGPQFSQQREEDIYRF
10 20 30 40
120 130 140 150 160 170
pF1KE5 LKDNGPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKDNGPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKS
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE5 ASIIYQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASIIYQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAP
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE5 GDSSTWGTLVDPWGPQDIHMERSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATA
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_001 GDSSTWGTLVDPWGPQDIHMEQSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATA
170 180 190 200 210 220
300 310 320 330 340 350
pF1KE5 AGPEASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGPEASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSG
230 240 250 260 270 280
360 370 380 390 400 410
pF1KE5 EGEPGEDAGRRPADTQSRSHFPRDIGQPITPSHSKLTPKLETMTLGNRSHKAAEGSHYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGEPGEDAGRRPADTQSRSHFPRDIGQPITPSHSKLTPKLETMTLGNRSHKAAEGSHYVD
290 300 310 320 330 340
420
pF1KE5 EASHEGSWWGGGI
:::::::::::::
NP_001 EASHEGSWWGGGI
350
>>XP_011527360 (OMIM: 606750) PREDICTED: Z-DNA-binding p (357 aa)
initn: 1990 init1: 1990 opt: 1992 Z-score: 1556.8 bits: 296.9 E(85289): 5.7e-80
Smith-Waterman score: 1992; 96.4% identity (98.0% similar) in 304 aa overlap (1-304:1-303)
10 20 30 40 50 60
pF1KE5 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRFLKDN
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_011 TSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TWGTLVDPWGPQDIHMERSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
:::::::::::::::::.:::::::::::::::::::::::::::::::::: . : .
XP_011 TWGTLVDPWGPQDIHMEQSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVFQCS-GKQ
250 260 270 280 290
310 320 330 340 350 360
pF1KE5 ASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEP
:. :
XP_011 AAEERGAESQRKTLTSRSAGRDQWGRPTAGSVEQKDASQTAQQHERSLCHCCRPRSFV
300 310 320 330 340 350
>>NP_001153891 (OMIM: 606750) Z-DNA-binding protein 1 is (248 aa)
initn: 1532 init1: 1503 opt: 1507 Z-score: 1183.5 bits: 227.3 E(85289): 3.5e-59
Smith-Waterman score: 1507; 92.0% identity (94.4% similar) in 250 aa overlap (1-250:1-244)
10 20 30 40 50 60
pF1KE5 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRFLKDN
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_001 TSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
::::::::::::::::::::::::::::::::::::::::::::.. :. : : ..
NP_001 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGKS-----PKRAQG-GD
190 200 210 220 230
250 260 270 280 290 300
pF1KE5 TWGTLVDPWGPQDIHMERSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPE
: :: :
NP_001 LGGEPPDPLGGGKG
240
>>XP_016883575 (OMIM: 606750) PREDICTED: Z-DNA-binding p (245 aa)
initn: 1157 init1: 1134 opt: 1134 Z-score: 894.8 bits: 173.8 E(85289): 4.2e-43
Smith-Waterman score: 1134; 98.8% identity (99.4% similar) in 171 aa overlap (1-171:1-171)
10 20 30 40 50 60
pF1KE5 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRFLKDN
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 TSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASII
:::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 GPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEASGGPTDNSLQG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSS
XP_016 LPGGRGVLARLTRDSFLEAWPKVCSCRRPVNGTEVAHSQCSQLWGAGISLSLGMVFFEHF
190 200 210 220 230 240
>>NP_001310895 (OMIM: 606750) Z-DNA-binding protein 1 is (173 aa)
initn: 1040 init1: 925 opt: 935 Z-score: 742.9 bits: 145.2 E(85289): 1.2e-34
Smith-Waterman score: 935; 87.8% identity (91.5% similar) in 164 aa overlap (87-250:12-169)
60 70 80 90 100 110
pF1KE5 KVSLTSPATWCLGGTDPEGEGPAELALSSPAKRPQQHAATIPETPGPQFSQQREEDIYRF
:.::::::::::::::::::::::::::::
NP_001 MAQAPADPGREAERPQQHAATIPETPGPQFSQQREEDIYRF
10 20 30 40
120 130 140 150 160 170
pF1KE5 LKDNGPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKDNGPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKS
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE5 ASIIYQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAP
::::::::::::::::::::::::::::::::::::::::::::::::.. :. :
NP_001 ASIIYQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGKS-----PKRAQ
110 120 130 140 150
240 250 260 270 280 290
pF1KE5 GDSSTWGTLVDPWGPQDIHMERSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATA
: .. : :: :
NP_001 G-GDLGGEPPDPLGGGKG
160 170
429 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:46:29 2016 done: Tue Nov 8 01:46:30 2016
Total Scan time: 9.160 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]