Result of FASTA (omim) for
pFN21AE5551
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5551, 411 aa
1>>>pF1KE5551 411 - 411 aa - 411 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8859+/-0.00049; mu= 14.0001+/- 0.030
mean_var=91.1798+/-18.833, 0's: 0 Z-trim(110.1): 137 B-trim: 579 in 2/48
Lambda= 0.134315
statistics sampled from 18262 (18412) to 18262 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.216), width: 16
Scan time: 7.890
The best scores are: opt bits E(85289)
NP_001135440 (OMIM: 606791) phosphatidylinositol 3 ( 411) 2771 547.8 1.8e-155
NP_954863 (OMIM: 606791) phosphatidylinositol 3,4, ( 522) 2400 476.0 9.6e-134
NP_570141 (OMIM: 606791) phosphatidylinositol 3,4, ( 445) 2395 475.0 1.7e-133
NP_001277153 (OMIM: 604336) putative tyrosine-prot ( 413) 2043 406.7 5.3e-113
NP_954869 (OMIM: 604336) putative tyrosine-protein ( 513) 2043 406.8 6.3e-113
NP_954868 (OMIM: 604336) putative tyrosine-protein ( 533) 2043 406.8 6.5e-113
NP_954870 (OMIM: 604336) putative tyrosine-protein ( 551) 2043 406.8 6.7e-113
NP_001258779 (OMIM: 606791) phosphatidylinositol 3 ( 193) 1327 267.7 1.7e-71
NP_001291646 (OMIM: 153480,155600,158350,176807,18 ( 576) 669 140.6 9.8e-33
NP_000305 (OMIM: 153480,155600,158350,176807,18847 ( 403) 657 138.1 3.7e-32
NP_073585 (OMIM: 606825) tensin-3 [Homo sapiens] (1445) 417 92.0 1e-17
XP_011513783 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 417 92.0 1e-17
XP_011513785 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 417 92.0 1e-17
XP_011513784 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 417 92.0 1e-17
XP_011513782 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 417 92.0 1e-17
XP_016868028 (OMIM: 606825) PREDICTED: tensin-3 is (1445) 417 92.0 1e-17
XP_011513781 (OMIM: 606825) PREDICTED: tensin-3 is (1488) 417 92.0 1e-17
XP_011513780 (OMIM: 606825) PREDICTED: tensin-3 is (1534) 417 92.0 1.1e-17
XP_016868026 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 417 92.0 1.1e-17
XP_011513779 (OMIM: 606825) PREDICTED: tensin-3 is (1548) 417 92.0 1.1e-17
XP_016868027 (OMIM: 606825) PREDICTED: tensin-3 is (1559) 417 92.0 1.1e-17
XP_011513778 (OMIM: 606825) PREDICTED: tensin-3 is (1561) 417 92.0 1.1e-17
NP_001294952 (OMIM: 600076) tensin-1 isoform 3 [Ho (1714) 412 91.1 2.3e-17
XP_011510025 (OMIM: 600076) PREDICTED: tensin-1 is (1714) 412 91.1 2.3e-17
NP_001294951 (OMIM: 600076) tensin-1 isoform 2 [Ho (1721) 412 91.1 2.3e-17
XP_016860297 (OMIM: 600076) PREDICTED: tensin-1 is (1727) 412 91.1 2.3e-17
NP_072174 (OMIM: 600076) tensin-1 isoform 1 [Homo (1735) 412 91.1 2.3e-17
XP_016860296 (OMIM: 600076) PREDICTED: tensin-1 is (1802) 412 91.1 2.4e-17
XP_016860301 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 412 91.1 2.4e-17
XP_016860300 (OMIM: 600076) PREDICTED: tensin-1 is (1808) 412 91.1 2.4e-17
XP_016860295 (OMIM: 600076) PREDICTED: tensin-1 is (1815) 412 91.1 2.4e-17
XP_016860294 (OMIM: 600076) PREDICTED: tensin-1 is (1824) 412 91.1 2.4e-17
XP_011510017 (OMIM: 600076) PREDICTED: tensin-1 is (1831) 412 91.1 2.4e-17
XP_011510015 (OMIM: 600076) PREDICTED: tensin-1 is (1839) 412 91.1 2.4e-17
XP_011510014 (OMIM: 600076) PREDICTED: tensin-1 is (1844) 412 91.1 2.4e-17
XP_016860293 (OMIM: 600076) PREDICTED: tensin-1 is (1852) 412 91.1 2.4e-17
XP_016860292 (OMIM: 600076) PREDICTED: tensin-1 is (1867) 412 91.1 2.4e-17
XP_016860291 (OMIM: 600076) PREDICTED: tensin-1 is (1880) 412 91.1 2.4e-17
XP_016860290 (OMIM: 600076) PREDICTED: tensin-1 is (1895) 412 91.1 2.5e-17
XP_016860299 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 412 91.1 2.5e-17
XP_016860298 (OMIM: 600076) PREDICTED: tensin-1 is (1896) 412 91.1 2.5e-17
XP_016863484 (OMIM: 602052) PREDICTED: cyclin-G-as (1131) 404 89.4 4.8e-17
XP_016863483 (OMIM: 602052) PREDICTED: cyclin-G-as (1197) 404 89.4 5e-17
XP_011511736 (OMIM: 602052) PREDICTED: cyclin-G-as (1219) 404 89.4 5.1e-17
XP_016863482 (OMIM: 602052) PREDICTED: cyclin-G-as (1219) 404 89.4 5.1e-17
NP_001305063 (OMIM: 602052) cyclin-G-associated ki (1232) 404 89.5 5.1e-17
XP_005272327 (OMIM: 602052) PREDICTED: cyclin-G-as (1236) 404 89.5 5.1e-17
XP_016863481 (OMIM: 602052) PREDICTED: cyclin-G-as (1246) 404 89.5 5.2e-17
XP_011511734 (OMIM: 602052) PREDICTED: cyclin-G-as (1267) 404 89.5 5.2e-17
XP_011511733 (OMIM: 602052) PREDICTED: cyclin-G-as (1272) 404 89.5 5.2e-17
>>NP_001135440 (OMIM: 606791) phosphatidylinositol 3,4,5 (411 aa)
initn: 2771 init1: 2771 opt: 2771 Z-score: 2912.1 bits: 547.8 E(85289): 1.8e-155
Smith-Waterman score: 2771; 99.8% identity (100.0% similar) in 411 aa overlap (1-411:1-411)
10 20 30 40 50 60
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DLKVQVVMEKKVVFSSTSLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYY
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 DLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYY
310 320 330 340 350 360
370 380 390 400 410
pF1KE5 DNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
370 380 390 400 410
>>NP_954863 (OMIM: 606791) phosphatidylinositol 3,4,5-tr (522 aa)
initn: 2753 init1: 2395 opt: 2400 Z-score: 2522.1 bits: 476.0 E(85289): 9.6e-134
Smith-Waterman score: 2400; 96.7% identity (98.6% similar) in 364 aa overlap (48-411:161-522)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .:::::::::::::::::
NP_954 GRQQYFSDLFNILDTAIIVIPLLVDVIYIFFDIKLLRNIP--RWTHLVRLLRLIILIRIF
140 150 160 170 180
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
190 200 210 220 230 240
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
250 260 270 280 290 300
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
370 380 390 400 410 420
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_954 SLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
430 440 450 460 470 480
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
::::::::::::::::::::::::::::::::::
NP_954 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
490 500 510 520
>--
initn: 459 init1: 372 opt: 373 Z-score: 399.3 bits: 83.2 E(85289): 1.7e-15
Smith-Waterman score: 373; 83.3% identity (95.8% similar) in 72 aa overlap (1-72:1-71)
10 20 30 40 50 60
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_954 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
... .... :.
NP_954 -SKIKKIVHSIVSSFAFGIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFF
70 80 90 100 110
>>NP_570141 (OMIM: 606791) phosphatidylinositol 3,4,5-tr (445 aa)
initn: 2633 init1: 2395 opt: 2395 Z-score: 2517.9 bits: 475.0 E(85289): 1.7e-133
Smith-Waterman score: 2547; 88.0% identity (89.6% similar) in 443 aa overlap (3-411:3-445)
10 20 30 40 50
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLER----------LSKFEV
::::::::::::::::::::::::::::::::::::: .. :. .
NP_570 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRIFGVFLVLLDVTLLLADLIF
10 20 30 40 50 60
60 70 80
pF1KE5 EDAENVASYE------------------------WTHLVRLLRLIILIRIFHLLHQKRQL
:.. : ::::::::::::::::::::::::::
NP_570 TDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGWTHLVRLLRLIILIRIFHLLHQKRQL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE5 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE5 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE5 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE5 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE5 DIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_570 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL
370 380 390 400 410 420
390 400 410
pF1KE5 DNPHKQKAWKIYPPEFAVEILFGEK
:::::::::::::::::::::::::
NP_570 DNPHKQKAWKIYPPEFAVEILFGEK
430 440
>>NP_001277153 (OMIM: 604336) putative tyrosine-protein (413 aa)
initn: 2038 init1: 2038 opt: 2043 Z-score: 2149.7 bits: 406.7 E(85289): 5.3e-113
Smith-Waterman score: 2043; 83.0% identity (92.6% similar) in 364 aa overlap (48-411:41-402)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
NP_001 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
20 30 40 50 60
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
NP_001 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
NP_001 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.::::::
NP_001 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
NP_001 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
NP_001 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
310 320 330 340 350 360
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
NP_001 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
370 380 390 400 410
>>NP_954869 (OMIM: 604336) putative tyrosine-protein pho (513 aa)
initn: 2143 init1: 2038 opt: 2043 Z-score: 2148.4 bits: 406.8 E(85289): 6.3e-113
Smith-Waterman score: 2043; 83.0% identity (92.6% similar) in 364 aa overlap (48-411:141-502)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
NP_954 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
120 130 140 150 160
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
NP_954 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
NP_954 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.::::::
NP_954 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
NP_954 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
350 360 370 380 390 400
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
NP_954 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
410 420 430 440 450 460
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
NP_954 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
470 480 490 500 510
>>NP_954868 (OMIM: 604336) putative tyrosine-protein pho (533 aa)
initn: 2239 init1: 2038 opt: 2043 Z-score: 2148.1 bits: 406.8 E(85289): 6.5e-113
Smith-Waterman score: 2043; 83.0% identity (92.6% similar) in 364 aa overlap (48-411:161-522)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
NP_954 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
140 150 160 170 180
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
NP_954 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
190 200 210 220 230 240
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
NP_954 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
250 260 270 280 290 300
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.::::::
NP_954 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
NP_954 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
370 380 390 400 410 420
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
NP_954 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
430 440 450 460 470 480
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
NP_954 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
490 500 510 520 530
>--
initn: 335 init1: 215 opt: 218 Z-score: 236.9 bits: 53.2 E(85289): 1.9e-06
Smith-Waterman score: 218; 47.5% identity (76.2% similar) in 80 aa overlap (1-80:1-79)
10 20 30 40 50 60
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
:::::. ... :. : ..::.:::::::. .: ..:.: ::::::::::::::::.
NP_954 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESVLARLSKFEVEDAENVASYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
... .... :. : :.
NP_954 -SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSKLYIPLEYRSISLAIALFF
70 80 90 100 110
>>NP_954870 (OMIM: 604336) putative tyrosine-protein pho (551 aa)
initn: 2348 init1: 2038 opt: 2043 Z-score: 2147.9 bits: 406.8 E(85289): 6.7e-113
Smith-Waterman score: 2043; 83.0% identity (92.6% similar) in 364 aa overlap (48-411:179-540)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
NP_954 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
150 160 170 180 190 200
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
NP_954 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
210 220 230 240 250 260
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
NP_954 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
270 280 290 300 310 320
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.::::::
NP_954 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVE
330 340 350 360 370 380
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
NP_954 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
390 400 410 420 430 440
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
NP_954 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
450 460 470 480 490 500
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
NP_954 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
510 520 530 540 550
>--
initn: 413 init1: 315 opt: 327 Z-score: 350.8 bits: 74.3 E(85289): 8.4e-13
Smith-Waterman score: 327; 68.4% identity (87.3% similar) in 79 aa overlap (2-80:20-97)
10 20 30 40
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSML
:.::::.::::.::::::::::::::::::: :::::.:.:
NP_954 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYT
::::::::::::::::. ... .... :. : :.
NP_954 ARLSKFEVEDAENVASYD-SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSK
70 80 90 100 110
110 120 130 140 150 160
pF1KE5 RDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYD
NP_954 LYIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFF
120 130 140 150 160 170
>>NP_001258779 (OMIM: 606791) phosphatidylinositol 3,4,5 (193 aa)
initn: 1327 init1: 1327 opt: 1327 Z-score: 1404.6 bits: 267.7 E(85289): 1.7e-71
Smith-Waterman score: 1327; 99.5% identity (100.0% similar) in 193 aa overlap (219-411:1-193)
190 200 210 220 230 240
pF1KE5 FTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKT
::::::::::::::::::::::::::::::
NP_001 MVCALLIASEIFLTAEESLYYFGERRTNKT
10 20 30
250 260 270 280 290 300
pF1KE5 HSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVM
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE5 EKKVVFSSTSLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFW
::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::
NP_001 EKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFW
100 110 120 130 140 150
370 380 390 400 410
pF1KE5 FNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:::::::::::::::::::::::::::::::::::::::::::
NP_001 FNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
160 170 180 190
>>NP_001291646 (OMIM: 153480,155600,158350,176807,188470 (576 aa)
initn: 733 init1: 588 opt: 669 Z-score: 708.7 bits: 140.6 E(85289): 9.8e-33
Smith-Waterman score: 750; 32.8% identity (59.2% similar) in 451 aa overlap (6-408:84-520)
10 20 30
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVS
........ . : : : ..: : : ..
NP_001 IQGPGPVLNLPSAAAAPPVARAPEAAGGGSRSEDYSSSPHSAAAAARPLAAEEKQAQSLQ
60 70 80 90 100 110
40 50 60 70 80
pF1KE5 PISK---SMLERLSKFEVEDAENVASYEWTHLVRLLR-------LIILIRIFHLLHQKRQ
: :. : . .. ..... .. . .:. :. . : . :. .
NP_001 PSSSRRSSHYPAAVQSQAAAERGASATAKSRAISILQKKPRHQQLLPSLSSFFFSHRLPD
120 130 140 150 160 170
90 100 110 120 130 140
pF1KE5 LEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKK
. .....::.::::: .:::::::::. ::::.::. .. ::: :..::::::.:
NP_001 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSK
180 190 200 210 220 230
150 160 170 180 190 200
pF1KE5 HRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIV
:.:::..::::.:: :: .:. ::.. ..::: : :. . : .....:...: ....
NP_001 HKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVA
240 250 260 270 280 290
210 220 230 240 250 260
pF1KE5 AIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYV
:::::.::::::.:.:: :. :: :.:.: ..:: :: .: .:: ::: :::
NP_001 AIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRT----RDK-KGVTIPSQRRYV
300 310 320 330 340
270 280 290 300 310 320
pF1KE5 GYFAQV--KHLYNWNLPPRRILFIKRFI--IYSIRGDVCDLKVQVVMEKKVVFSSTSLGN
:.. . .:: . : .:: : .. : . : .:. . : . : ..::.: :
NP_001 YYYSYLLKNHL---DYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNS-GP
350 360 370 380 390 400
330 340 350 360 370
pF1KE5 CSILHDIETDKVLINVYDGP-PLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFI------
. :: . . : :. :.::.:: .. . : :: :: ::
NP_001 TR-----REDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEET
410 420 430 440 450
380 390 400
pF1KE5 ----QNNRLC-----------------------LPRNELDNPHKQKAWKIYPPEFAVEIL
.:. :: : .:.::. .:.:: . . :.: :..
NP_001 SEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLY
460 470 480 490 500 510
410
pF1KE5 FGEK
:
NP_001 FTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
520 530 540 550 560 570
>>NP_000305 (OMIM: 153480,155600,158350,176807,188470,27 (403 aa)
initn: 733 init1: 588 opt: 657 Z-score: 698.4 bits: 138.1 E(85289): 3.7e-32
Smith-Waterman score: 737; 37.4% identity (61.5% similar) in 361 aa overlap (86-408:1-347)
60 70 80 90 100 110
pF1KE5 VASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTE
. .....::.::::: .:::::::::.
NP_000 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP
10 20 30
120 130 140 150 160 170
pF1KE5 RIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMI
::::.::. .. ::: :..::::::.::.:::..::::.:: :: .:. ::.. .
NP_000 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE5 DDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEE
.::: : :. . : .....:...: ....:::::.::::::.:.:: :. :: :.:
NP_000 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE5 SLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV--KHLYNWNLPPRRILFIKRFI--
.: ..:: :: .: .:: ::: ::: :.. . .:: . : .:: : ..
NP_000 ALDFYGEVRTR----DK-KGVTIPSQRRYVYYYSYLLKNHL---DYRPVALLFHKMMFET
160 170 180 190 200
300 310 320 330 340 350
pF1KE5 IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKVLINVYDGP-PLYDDVKVQ
: . : .:. . : . : ..::.: : . :: . . : :. :.::.
NP_000 IPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTR-----REDKFMYFEFPQPLPVCGDIKVE
210 220 230 240 250
360 370 380
pF1KE5 FFSSNLPKYYDNCPFFFWFNTSFI----------QNNRLC--------------------
:: .. . : :: :: :: .:. ::
NP_000 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL
260 270 280 290 300 310
390 400 410
pF1KE5 ---LPRNELDNPHKQKAWKIYPPEFAVEILFGEK
: .:.::. .:.:: . . :.: :.. :
NP_000 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH
320 330 340 350 360 370
NP_000 YRYSDTTDSDPENEPFDEDQHTQITKV
380 390 400
411 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:44:45 2016 done: Tue Nov 8 01:44:46 2016
Total Scan time: 7.890 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]