Result of FASTA (ccds) for
pFN21AE5551
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5551, 411 aa
1>>>pF1KE5551 411 - 411 aa - 411 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8400+/-0.00108; mu= 13.7448+/- 0.065
mean_var=74.2355+/-14.669, 0's: 0 Z-trim(103.3): 62 B-trim: 75 in 1/47
Lambda= 0.148857
statistics sampled from 7293 (7347) to 7293 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.597), E-opt: 0.2 (0.226), width: 16
Scan time: 2.700
The best scores are: opt bits E(32554)
CCDS45013.1 TPTE2 gene_id:93492|Hs108|chr13 ( 411) 2771 604.9 4.3e-173
CCDS45014.1 TPTE2 gene_id:93492|Hs108|chr13 ( 522) 2400 525.3 5.2e-149
CCDS9285.1 TPTE2 gene_id:93492|Hs108|chr13 ( 445) 2395 524.2 9.4e-149
CCDS77617.1 TPTE gene_id:7179|Hs108|chr21 ( 413) 2038 447.5 1.1e-125
CCDS74773.1 TPTE gene_id:7179|Hs108|chr21 ( 513) 2038 447.6 1.3e-125
CCDS74772.1 TPTE gene_id:7179|Hs108|chr21 ( 533) 2038 447.6 1.3e-125
CCDS74771.1 TPTE gene_id:7179|Hs108|chr21 ( 551) 2038 447.6 1.4e-125
CCDS31238.1 PTEN gene_id:5728|Hs108|chr10 ( 403) 657 150.9 2e-36
CCDS5506.2 TNS3 gene_id:64759|Hs108|chr7 (1445) 417 99.6 2e-20
CCDS77528.1 TNS1 gene_id:7145|Hs108|chr2 (1714) 412 98.6 4.8e-20
CCDS77529.1 TNS1 gene_id:7145|Hs108|chr2 (1721) 412 98.6 4.8e-20
CCDS2407.1 TNS1 gene_id:7145|Hs108|chr2 (1735) 412 98.6 4.8e-20
CCDS82902.1 GAK gene_id:2580|Hs108|chr4 (1232) 404 96.8 1.2e-19
CCDS3340.1 GAK gene_id:2580|Hs108|chr4 (1311) 404 96.8 1.2e-19
CCDS8843.1 TNS2 gene_id:23371|Hs108|chr12 (1409) 337 82.5 2.9e-15
CCDS8842.1 TNS2 gene_id:23371|Hs108|chr12 (1419) 337 82.5 2.9e-15
CCDS8844.1 TNS2 gene_id:23371|Hs108|chr12 (1285) 335 82.0 3.5e-15
CCDS58005.1 DNAJC6 gene_id:9829|Hs108|chr1 ( 900) 328 80.4 7.4e-15
CCDS30739.1 DNAJC6 gene_id:9829|Hs108|chr1 ( 913) 328 80.4 7.5e-15
CCDS58004.1 DNAJC6 gene_id:9829|Hs108|chr1 ( 970) 328 80.4 7.9e-15
>>CCDS45013.1 TPTE2 gene_id:93492|Hs108|chr13 (411 aa)
initn: 2771 init1: 2771 opt: 2771 Z-score: 3221.0 bits: 604.9 E(32554): 4.3e-173
Smith-Waterman score: 2771; 99.8% identity (100.0% similar) in 411 aa overlap (1-411:1-411)
10 20 30 40 50 60
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 PTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 DLKVQVVMEKKVVFSSTSLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYY
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
CCDS45 DLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYY
310 320 330 340 350 360
370 380 390 400 410
pF1KE5 DNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DNCPFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
370 380 390 400 410
>>CCDS45014.1 TPTE2 gene_id:93492|Hs108|chr13 (522 aa)
initn: 2753 init1: 2395 opt: 2400 Z-score: 2788.8 bits: 525.3 E(32554): 5.2e-149
Smith-Waterman score: 2400; 96.7% identity (98.6% similar) in 364 aa overlap (48-411:161-522)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .:::::::::::::::::
CCDS45 GRQQYFSDLFNILDTAIIVIPLLVDVIYIFFDIKLLRNIP--RWTHLVRLLRLIILIRIF
140 150 160 170 180
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
190 200 210 220 230 240
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
250 260 270 280 290 300
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
370 380 390 400 410 420
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SLGNCSILHDIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
430 440 450 460 470 480
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
::::::::::::::::::::::::::::::::::
CCDS45 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
490 500 510 520
>--
initn: 459 init1: 372 opt: 373 Z-score: 436.2 bits: 90.0 E(32554): 5.7e-18
Smith-Waterman score: 373; 83.3% identity (95.8% similar) in 72 aa overlap (1-72:1-71)
10 20 30 40 50 60
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS45 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAM
... .... :.
CCDS45 -SKIKKIVHSIVSSFAFGIFGVFLVLLDVTLLLADLIFTDSKLYIPLEYRSISLAIGLFF
70 80 90 100 110
>>CCDS9285.1 TPTE2 gene_id:93492|Hs108|chr13 (445 aa)
initn: 2633 init1: 2395 opt: 2395 Z-score: 2784.0 bits: 524.2 E(32554): 9.4e-149
Smith-Waterman score: 2547; 88.0% identity (89.6% similar) in 443 aa overlap (3-411:3-445)
10 20 30 40 50
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSMLER----------LSKFEV
::::::::::::::::::::::::::::::::::::: .. :. .
CCDS92 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKRIFGVFLVLLDVTLLLADLIF
10 20 30 40 50 60
60 70 80
pF1KE5 EDAENVASYE------------------------WTHLVRLLRLIILIRIFHLLHQKRQL
:.. : ::::::::::::::::::::::::::
CCDS92 TDSKLYIPLEYRSISLAIGLFFLMDVLLRVFVEGWTHLVRLLRLIILIRIFHLLHQKRQL
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE5 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 EKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKH
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE5 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 RNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDLENIVA
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE5 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 IHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVETPSQNRYVG
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE5 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 YFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILH
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE5 DIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS92 DIETDKILINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNNRLCLPRNEL
370 380 390 400 410 420
390 400 410
pF1KE5 DNPHKQKAWKIYPPEFAVEILFGEK
:::::::::::::::::::::::::
CCDS92 DNPHKQKAWKIYPPEFAVEILFGEK
430 440
>>CCDS77617.1 TPTE gene_id:7179|Hs108|chr21 (413 aa)
initn: 2033 init1: 2033 opt: 2038 Z-score: 2370.2 bits: 447.5 E(32554): 1.1e-125
Smith-Waterman score: 2038; 82.7% identity (92.6% similar) in 364 aa overlap (48-411:41-402)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
CCDS77 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
20 30 40 50 60
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
CCDS77 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
CCDS77 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.:::::.
CCDS77 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
CCDS77 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
CCDS77 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
310 320 330 340 350 360
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
CCDS77 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
370 380 390 400 410
>>CCDS74773.1 TPTE gene_id:7179|Hs108|chr21 (513 aa)
initn: 2138 init1: 2033 opt: 2038 Z-score: 2368.7 bits: 447.6 E(32554): 1.3e-125
Smith-Waterman score: 2038; 82.7% identity (92.6% similar) in 364 aa overlap (48-411:141-502)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
CCDS74 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
120 130 140 150 160
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
CCDS74 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
CCDS74 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.:::::.
CCDS74 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVK
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
CCDS74 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
350 360 370 380 390 400
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
CCDS74 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
410 420 430 440 450 460
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
CCDS74 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
470 480 490 500 510
>>CCDS74772.1 TPTE gene_id:7179|Hs108|chr21 (533 aa)
initn: 2234 init1: 2033 opt: 2038 Z-score: 2368.5 bits: 447.6 E(32554): 1.3e-125
Smith-Waterman score: 2038; 82.7% identity (92.6% similar) in 364 aa overlap (48-411:161-522)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
CCDS74 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
140 150 160 170 180
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
CCDS74 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
190 200 210 220 230 240
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
CCDS74 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
250 260 270 280 290 300
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.:::::.
CCDS74 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVK
310 320 330 340 350 360
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
CCDS74 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
370 380 390 400 410 420
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
CCDS74 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
430 440 450 460 470 480
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
CCDS74 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
490 500 510 520 530
>>CCDS74771.1 TPTE gene_id:7179|Hs108|chr21 (551 aa)
initn: 2343 init1: 2033 opt: 2038 Z-score: 2368.2 bits: 447.6 E(32554): 1.4e-125
Smith-Waterman score: 2038; 82.7% identity (92.6% similar) in 364 aa overlap (48-411:179-540)
20 30 40 50 60 70
pF1KE5 PAKESPHTSEFKGAALVSPISKSMLERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIF
:... .:. .::::.::::::::.:::
CCDS74 RRQQYFSDLFNILDTAIIVILLLVDVVYIFFDIKLLRNIP--RWTHLLRLLRLIILLRIF
150 160 170 180 190 200
80 90 100 110 120 130
pF1KE5 HLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEE
::.:::::::::.:: ::::::::::::::::::::::::::::::::::::::::::.:
CCDS74 HLFHQKRQLEKLIRRRVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIKE
210 220 230 240 250 260
140 150 160 170 180 190
pF1KE5 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWM
::::::::::::::::::::::::::::::::: :::::::::::::.::::::::::::
CCDS74 VVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVVRIMIDDHNVPTLHQMVVFTKEVNEWM
270 280 290 300 310 320
200 210 220 230 240 250
pF1KE5 AQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKFQGVE
::::::::::::::: ::::::::.:::::: ::.:::::::::::.::::.:::::.
CCDS74 AQDLENIVAIHCKGGTDRTGTMVCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVK
330 340 350 360 370 380
260 270 280 290 300 310
pF1KE5 TPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSST
::::.:::.::::::::::::::::::::::.:::::: : :::.:. ::::::::.
CCDS74 TPSQKRYVAYFAQVKHLYNWNLPPRRILFIKHFIIYSIPRYVRDLKIQIEMEKKVVFSTI
390 400 410 420 430 440
320 330 340 350 360 370
pF1KE5 SLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQNN
:::.::.: .: :::.::.:.:: ::::::::::: :::: ::::: :.::..::::.::
CCDS74 SLGKCSVLDNITTDKILIDVFDGLPLYDDVKVQFFYSNLPTYYDNCSFYFWLHTSFIENN
450 460 470 480 490 500
380 390 400 410
pF1KE5 RLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:: ::.::::: ::::: .::: .::::::::::
CCDS74 RLYLPKNELDNLHKQKARRIYPSDFAVEILFGEKMTSSDVVAGSD
510 520 530 540 550
>--
initn: 413 init1: 315 opt: 327 Z-score: 382.4 bits: 80.1 E(32554): 5.6e-15
Smith-Waterman score: 327; 68.4% identity (87.3% similar) in 79 aa overlap (2-80:20-97)
10 20 30 40
pF1KE5 MNESPQTNEFKGTTEEAPAKESPHTSEFKGAALVSPISKSML
:.::::.::::.::::::::::::::::::: :::::.:.:
CCDS74 MNESPDPTDLAGVIIELGPNDSPQTSEFKGATEEAPAKESPHTSEFKGAARVSPISESVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ERLSKFEVEDAENVASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYT
::::::::::::::::. ... .... :. : :.
CCDS74 ARLSKFEVEDAENVASYD-SKIKKIVHSIVSSFAFGLFGVFLVLLDVTLILADLIFTDSK
70 80 90 100 110
110 120 130 140 150 160
pF1KE5 RDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYD
CCDS74 LYIPLEYRSISLAIALFFLMDVLLRVFVERRQQYFSDLFNILDTAIIVILLLVDVVYIFF
120 130 140 150 160 170
>>CCDS31238.1 PTEN gene_id:5728|Hs108|chr10 (403 aa)
initn: 733 init1: 588 opt: 657 Z-score: 767.5 bits: 150.9 E(32554): 2e-36
Smith-Waterman score: 737; 37.4% identity (61.5% similar) in 361 aa overlap (86-408:1-347)
60 70 80 90 100 110
pF1KE5 VASYEWTHLVRLLRLIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTE
. .....::.::::: .:::::::::.
CCDS31 MTAIIKEIVSRNKRRYQEDGFDLDLTYIYP
10 20 30
120 130 140 150 160 170
pF1KE5 RIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMI
::::.::. .. ::: :..::::::.::.:::..::::.:: :: .:. ::.. .
CCDS31 NIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPF
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE5 DDHNVPTLHEMVVFTKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEE
.::: : :. . : .....:...: ....:::::.::::::.:.:: :. :: :.:
CCDS31 EDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQE
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE5 SLYYFGERRTNKTHSNKFQGVETPSQNRYVGYFAQV--KHLYNWNLPPRRILFIKRFI--
.: ..:: :: .: .:: ::: ::: :.. . .:: . : .:: : ..
CCDS31 ALDFYGEVRTR----DK-KGVTIPSQRRYVYYYSYLLKNHL---DYRPVALLFHKMMFET
160 170 180 190 200
300 310 320 330 340 350
pF1KE5 IYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKVLINVYDGP-PLYDDVKVQ
: . : .:. . : . : ..::.: : . :: . . : :. :.::.
CCDS31 IPMFSGGTCNPQFVVCQLKVKIYSSNS-GPTR-----REDKFMYFEFPQPLPVCGDIKVE
210 220 230 240 250
360 370 380
pF1KE5 FFSSNLPKYYDNCPFFFWFNTSFI----------QNNRLC--------------------
:: .. . : :: :: :: .:. ::
CCDS31 FFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYL
260 270 280 290 300 310
390 400 410
pF1KE5 ---LPRNELDNPHKQKAWKIYPPEFAVEILFGEK
: .:.::. .:.:: . . :.: :.. :
CCDS31 VLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDH
320 330 340 350 360 370
CCDS31 YRYSDTTDSDPENEPFDEDQHTQITKV
380 390 400
>>CCDS5506.2 TNS3 gene_id:64759|Hs108|chr7 (1445 aa)
initn: 358 init1: 168 opt: 417 Z-score: 480.3 bits: 99.6 E(32554): 2e-20
Smith-Waterman score: 425; 27.7% identity (61.0% similar) in 310 aa overlap (104-408:3-298)
80 90 100 110 120 130
pF1KE5 IRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRN
.: :::::.::::::.:::.. . : .
CCDS55 MEEGHGLDLTYITERIIAVSFPAGCSEESYLH
10 20 30
140 150 160 170 180 190
pF1KE5 PIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVFTKEV
..::.:.: .:: ..: : :: ::. :: ... .. . . ..: : .: .. :
CCDS55 NLQEVTRMLKSKHGDNYLVLNL-SEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE5 NEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTHSNKF
. :. ..:...:.:::.::::: :... . . ... .:...: :. . : ...:
CCDS55 ESWLNSNLQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMK---KFYDDKV
100 110 120 130 140
260 270 280 290 300
pF1KE5 QGVETPSQNRYVGYFAQV-KHLYNWNLPPRRILFIKRFIIYSI----RGDVCDLKVQVVM
... :::.::: ... . . . : : ::.. :... : :: ... .
CCDS55 SALMQPSQKRYVQFLSGLLSGSVKMNASP---LFLHFVILHGTPNFDTGGVCRPFLKLYQ
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE5 EKKVVFSSTSLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNCPFFFW
. :..: : .. . . ... : . . : :: :. . .. . . : .
CCDS55 AMQPVYTS---GIYNVGPE-NPSRICIVIEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQ
210 220 230 240 250 260
370 380 390 400 410
pF1KE5 FNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFAVEILFGEK
:.:. .:. : . ...::: :. .: ::..:
CCDS55 FHTGAVQGYGLVFGKEDLDNASKDDR---FPDYGKVELVFSATPEKIQGSEHLYNDHGVI
270 280 290 300 310
CCDS55 VDYNTTDPLIRWDSYENLSADGEVLHTQGPVDGSLYAKVRKKSSSDPGIPGGPQAIPATN
320 330 340 350 360 370
>>CCDS77528.1 TNS1 gene_id:7145|Hs108|chr2 (1714 aa)
initn: 202 init1: 160 opt: 412 Z-score: 473.4 bits: 98.6 E(32554): 4.8e-20
Smith-Waterman score: 419; 29.4% identity (62.0% similar) in 316 aa overlap (100-408:5-304)
70 80 90 100 110 120
pF1KE5 LIILIRIFHLLHQKRQLEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQS
: .:. .:::.::::::::.::::.. .
CCDS77 MSVSRTMEDSCELDLVYVTERIIAVSFPSTANEE
10 20 30
130 140 150 160 170 180
pF1KE5 FYRNPIEEVVRFLDKKHRNHYRVYNLCSERAYDPKHFHNRVSRIMIDDHNVPTLHEMVVF
.:. ..::...: .:: ..: ..:: ::: : ..: .: .. : ..:.:... .
CCDS77 NFRSNLREVAQMLKSKHGGNYLLFNL-SERRPDITKLHAKVLEFGWPDLHTPALEKICSI
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE5 TKEVNEWMAQDLENIVAIHCKGGKGRTGTMVCALLIASEIFLTAEESLYYFGERRTNKTH
: .. :. : .:.:..: ::..:: :... : . :.: .:...: :. .: .
CCDS77 CKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRF---Y
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE5 SNKFQGVETPSQNRYVGYFAQV-KHLYNWNLPPRRILFIKRFIIYSI-----RGDVCDLK
.:. . ::: ::: ::. . . . : : ::... :...: .: :
CCDS77 EDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKP---LFLHHVIMHGIPNFESKGG-CRPF
160 170 180 190 200
310 320 330 340 350 360
pF1KE5 VQVVMEKKVVFSSTSLGNCSILHDIETDKVLINVYDGPPLYDDVKVQFFSSNLPKYYDNC
... . . :..: : .: : .:. : :.. : : :. .. . ... . .
CCDS77 LRIYQAMQPVYTS---GIYNIPGDSQTS-VCITIEPGLLLKGDILLKCYHKKFRSPARDV
210 220 230 240 250 260
370 380 390 400 410
pF1KE5 PFFFWFNTSFIQNNRLCLPRNELDNPHKQKAWKIYPPEFA-VEILFGEK
: :.: :.. . . ...::. :. . ::.. ::..:
CCDS77 IFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRF----PEYGKVEFVFSYGPEKIQGMEHLE
270 280 290 300 310
CCDS77 NGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLHGS
320 330 340 350 360 370
411 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:44:44 2016 done: Tue Nov 8 01:44:45 2016
Total Scan time: 2.700 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]