Result of FASTA (omim) for
pFN21AE5520
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5520, 464 aa
1>>>pF1KE5520 464 - 464 aa - 464 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2471+/-0.000408; mu= 17.7872+/- 0.025
mean_var=69.7109+/-14.047, 0's: 0 Z-trim(110.9): 160 B-trim: 71 in 1/52
Lambda= 0.153612
statistics sampled from 19167 (19344) to 19167 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.59), E-opt: 0.2 (0.227), width: 16
Scan time: 5.440
The best scores are: opt bits E(85289)
NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 3128 702.8 4.9e-202
XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424) 2872 646.1 5.5e-185
NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457) 2504 564.5 2.1e-160
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 2391 539.5 7.1e-153
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 2387 538.6 1.3e-152
XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465) 2365 533.7 4e-151
XP_011530569 (OMIM: 600421) PREDICTED: glycine rec ( 313) 2076 469.6 5.5e-132
XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452) 2030 459.5 8.6e-129
NP_001112358 (OMIM: 305990) glycine receptor subun ( 452) 2030 459.5 8.6e-129
NP_001112357 (OMIM: 305990) glycine receptor subun ( 452) 2024 458.1 2.2e-128
NP_002054 (OMIM: 305990) glycine receptor subunit ( 452) 2024 458.1 2.2e-128
XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436) 2022 457.7 2.9e-128
XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436) 2022 457.7 2.9e-128
XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436) 2022 457.7 2.9e-128
NP_001278929 (OMIM: 138491,149400) glycine recepto ( 366) 1977 447.7 2.5e-125
XP_011530570 (OMIM: 600421) PREDICTED: glycine rec ( 269) 1811 410.8 2.3e-114
XP_016884918 (OMIM: 305990) PREDICTED: glycine rec ( 363) 1696 385.4 1.4e-106
XP_016884917 (OMIM: 305990) PREDICTED: glycine rec ( 363) 1696 385.4 1.4e-106
NP_001165413 (OMIM: 305990) glycine receptor subun ( 363) 1696 385.4 1.4e-106
NP_001159532 (OMIM: 138492,614619) glycine recepto ( 497) 1218 279.6 1.4e-74
NP_000815 (OMIM: 138492,614619) glycine receptor s ( 497) 1218 279.6 1.4e-74
XP_016863524 (OMIM: 138492,614619) PREDICTED: glyc ( 303) 1040 240.0 6.9e-63
NP_001159533 (OMIM: 138492,614619) glycine recepto ( 303) 1040 240.0 6.9e-63
XP_016863523 (OMIM: 138492,614619) PREDICTED: glyc ( 399) 1033 238.5 2.5e-62
NP_000802 (OMIM: 137143) gamma-aminobutyric acid r ( 453) 978 226.3 1.3e-58
NP_000806 (OMIM: 137163,613060) gamma-aminobutyric ( 452) 965 223.5 9.7e-58
XP_011539496 (OMIM: 137163,613060) PREDICTED: gamm ( 465) 965 223.5 9.9e-58
XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 963 223.0 1.3e-57
XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 963 223.0 1.3e-57
NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 963 223.0 1.3e-57
NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 963 223.0 1.3e-57
XP_016856425 (OMIM: 137163,613060) PREDICTED: gamm ( 687) 965 223.6 1.4e-57
NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 943 218.6 2.9e-56
NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 940 217.9 4.7e-56
NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474) 940 217.9 4.7e-56
NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512) 940 218.0 5e-56
NP_001121117 (OMIM: 137160,611136,615744) gamma-am ( 456) 939 217.7 5.3e-56
NP_001121116 (OMIM: 137160,611136,615744) gamma-am ( 456) 939 217.7 5.3e-56
NP_001121115 (OMIM: 137160,611136,615744) gamma-am ( 456) 939 217.7 5.3e-56
NP_001121120 (OMIM: 137160,611136,615744) gamma-am ( 456) 939 217.7 5.3e-56
NP_000797 (OMIM: 137160,611136,615744) gamma-amino ( 456) 939 217.7 5.3e-56
NP_002034 (OMIM: 137162) gamma-aminobutyric acid r ( 465) 939 217.7 5.4e-56
NP_055026 (OMIM: 602729) gamma-aminobutyric acid r ( 440) 937 217.2 7e-56
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 934 216.6 1.2e-55
NP_000799 (OMIM: 305660) gamma-aminobutyric acid r ( 492) 929 215.5 2.6e-55
NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 928 215.3 3e-55
NP_001243632 (OMIM: 137161) gamma-aminobutyric aci ( 462) 927 215.0 3.4e-55
NP_002033 (OMIM: 137161) gamma-aminobutyric acid r ( 479) 927 215.1 3.5e-55
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 925 214.6 4.6e-55
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 921 213.7 8.7e-55
>>NP_006520 (OMIM: 600421) glycine receptor subunit alph (464 aa)
initn: 3128 init1: 3128 opt: 3128 Z-score: 3748.1 bits: 702.8 E(85289): 4.9e-202
Smith-Waterman score: 3128; 100.0% identity (100.0% similar) in 464 aa overlap (1-464:1-464)
10 20 30 40 50 60
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
370 380 390 400 410 420
430 440 450 460
pF1KE5 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
::::::::::::::::::::::::::::::::::::::::::::
NP_006 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
430 440 450 460
>>XP_016864119 (OMIM: 600421) PREDICTED: glycine recepto (424 aa)
initn: 2872 init1: 2872 opt: 2872 Z-score: 3442.1 bits: 646.1 E(85289): 5.5e-185
Smith-Waterman score: 2872; 100.0% identity (100.0% similar) in 424 aa overlap (41-464:1-424)
20 30 40 50 60 70
pF1KE5 VSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPV
::::::::::::::::::::::::::::::
XP_016 MSPSDFLDKLMGRTSGYDARIRPNFKGPPV
10 20 30
80 90 100 110 120 130
pF1KE5 NVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPD
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 LFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE5 SFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLE
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE5 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE5 SYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE5 DMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDT
340 350 360 370 380 390
440 450 460
pF1KE5 ISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
::::::::::::::::::::::::::::::::::
XP_016 ISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
400 410 420
>>NP_001139512 (OMIM: 138491,149400) glycine receptor su (457 aa)
initn: 2457 init1: 2320 opt: 2504 Z-score: 3000.8 bits: 564.5 E(85289): 2.1e-160
Smith-Waterman score: 2504; 81.5% identity (93.2% similar) in 455 aa overlap (14-462:9-457)
10 20 30 40 50 60
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
.:.::. ...::.:.::...::: :::::::::::::::::::::
NP_001 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDAR
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
::::::::::::.::::::::::::::::::::::::::.::::::::.:::::::::::
NP_001 IRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
:::::::::::::::::::.:::.::::::::: .:::::::::.::::.::::::::::
NP_001 SMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
::::::::::::::::::::::::... ::::.:::::::.:::::::::::::::::::
NP_001 DVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
::::.:::::::::::::::::::::::::::.:::::::::::::.:::::::::::::
NP_001 TCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::... ..
NP_001 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHH-KS
300 310 320 330 340 350
370 380 390 400 410
pF1KE5 FALEKFYRFSDMDDEVRESRFSFTAYGMGP-CLQAKDGMTPKGPNHPVQVMP-----KSP
:. : ..::. :.::.:.:::::: :::::::.. :: :. . : :::
NP_001 PMLNLF-----QEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSP
360 370 380 390 400
420 430 440 450 460
pF1KE5 DEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
.::::.::.:::::: ::: ::.::::::.:::.::::.:.::.:.:
NP_001 EEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
410 420 430 440 450
>>NP_001036008 (OMIM: 600421) glycine receptor subunit a (449 aa)
initn: 2385 init1: 2385 opt: 2391 Z-score: 2865.6 bits: 539.5 E(85289): 7.1e-153
Smith-Waterman score: 2991; 96.8% identity (96.8% similar) in 464 aa overlap (1-464:1-449)
10 20 30 40 50 60
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNK---
310 320 330 340 350
370 380 390 400 410 420
pF1KE5 FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------DDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
360 370 380 390 400
430 440 450 460
pF1KE5 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
410 420 430 440
>>NP_000162 (OMIM: 138491,149400) glycine receptor subun (449 aa)
initn: 2457 init1: 2136 opt: 2387 Z-score: 2860.8 bits: 538.6 E(85289): 1.3e-152
Smith-Waterman score: 2494; 81.3% identity (91.9% similar) in 455 aa overlap (14-462:9-449)
10 20 30 40 50 60
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
.:.::. ...::.:.::...::: :::::::::::::::::::::
NP_000 MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDAR
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
::::::::::::.::::::::::::::::::::::::::.::::::::.:::::::::::
NP_000 IRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
:::::::::::::::::::.:::.::::::::: .:::::::::.::::.::::::::::
NP_000 SMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPM
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
::::::::::::::::::::::::... ::::.:::::::.:::::::::::::::::::
NP_000 DVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
::::.:::::::::::::::::::::::::::.:::::::::::::.:::::::::::::
NP_000 TCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::... :
NP_000 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKE-
300 310 320 330 340 350
370 380 390 400 410
pF1KE5 FALEKFYRFSDMDDEVRESRFSFTAYGMGP-CLQAKDGMTPKGPNHPVQVMP-----KSP
::. :.::.:.:::::: :::::::.. :: :. . : :::
NP_000 -------------DEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSP
360 370 380 390 400
420 430 440 450 460
pF1KE5 DEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
.::::.::.:::::: ::: ::.::::::.:::.::::.:.::.:.:
NP_000 EEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
410 420 430 440
>>XP_016864838 (OMIM: 138491,149400) PREDICTED: glycine (465 aa)
initn: 2435 init1: 2114 opt: 2365 Z-score: 2834.2 bits: 533.7 E(85289): 4e-151
Smith-Waterman score: 2472; 82.4% identity (92.0% similar) in 448 aa overlap (21-462:32-465)
10 20 30 40 50
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKL
.::::.:.::...::: :::::::::::
XP_016 GIQPNLEPTLIKGNLYQHEKEPSLTFCSPLFLLSLAASKEAEAARSAPKPMSPSDFLDKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 MGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE
::::::::::::::::::::::.::::::::::::::::::::::::::.::::::::.:
XP_016 MGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLS
:::::::::::::::::::::::::::::.:::.::::::::: .:::::::::.::::.
XP_016 YPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 CPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRY
::::::::::::::::::::::::::::::::::... ::::.:::::::.:::::::::
XP_016 CPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 CTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGI
::::::::::::::.:::::::::::::::::::::::::::.:::::::::::::.:::
XP_016 CTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 TTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRF
310 320 330 340 350 360
360 370 380 390 400
pF1KE5 RRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGP-CLQAKDGMTPKGPNHPVQV
::::... : ::. :.::.:.:::::: :::::::.. :: :. .
XP_016 RRKRRHHKE--------------DEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTT
370 380 390 400
410 420 430 440 450 460
pF1KE5 MP-----KSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
: :::.::::.::.:::::: ::: ::.::::::.:::.::::.:.::.:.:
XP_016 NPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIVRREDVHNQ
410 420 430 440 450 460
>>XP_011530569 (OMIM: 600421) PREDICTED: glycine recepto (313 aa)
initn: 2122 init1: 2076 opt: 2076 Z-score: 2490.6 bits: 469.6 E(85289): 5.5e-132
Smith-Waterman score: 2076; 99.4% identity (100.0% similar) in 311 aa overlap (1-311:1-311)
10 20 30 40 50 60
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
:::::::::..
XP_011 SGSRASLPKANVS
310
>>XP_016884916 (OMIM: 305990) PREDICTED: glycine recepto (452 aa)
initn: 2388 init1: 2015 opt: 2030 Z-score: 2433.2 bits: 459.5 E(85289): 8.6e-129
Smith-Waterman score: 2387; 78.8% identity (88.8% similar) in 457 aa overlap (9-462:10-452)
10 20 30 40 50
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDA
: . .:.. . .. ... :... : .::::::::::::::::::
XP_016 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLD
::::::::::::::::::::::::::::::::::::::::.::: :::::::::::::::
XP_016 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 PSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFP
:::::::::::::::::::::::.:::::::::: :::.:::::::::::::::::::::
XP_016 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 MDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGK
:::::: ::::::::::::::::: ...:::::::::::::.:::::.: ::::::::::
XP_016 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRR--KRKNK
:::::::::::::::::::::::::::::.:::::::::::::::::.::.:: ::.::
XP_016 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 TEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKG-PNHPVQVMPKSPDE
: : .:::::.:..:::: :::.::: . :. : .:. ::. :
XP_016 EE--------------DVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDA
370 380 390 400
420 430 440 450 460
pF1KE5 MRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
..: :.::::.::::::: :::::::::::::. :::.::::.:..
XP_016 IKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
410 420 430 440 450
>>NP_001112358 (OMIM: 305990) glycine receptor subunit a (452 aa)
initn: 2388 init1: 2015 opt: 2030 Z-score: 2433.2 bits: 459.5 E(85289): 8.6e-129
Smith-Waterman score: 2387; 78.8% identity (88.8% similar) in 457 aa overlap (9-462:10-452)
10 20 30 40 50
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDA
: . .:.. . .. ... :... : .::::::::::::::::::
NP_001 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLD
::::::::::::::::::::::::::::::::::::::::.::: :::::::::::::::
NP_001 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 PSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFP
:::::::::::::::::::::::.:::::::::: :::.:::::::::::::::::::::
NP_001 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 MDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGK
:::::: ::::::::::::::::: ...:::::::::::::.:::::.: ::::::::::
NP_001 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRR--KRKNK
:::::::::::::::::::::::::::::.:::::::::::::::::.::.:: ::.::
NP_001 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 TEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKG-PNHPVQVMPKSPDE
: : .:::::.:..:::: :::.::: . :. : .:. ::. :
NP_001 EE--------------DVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDA
370 380 390 400
420 430 440 450 460
pF1KE5 MRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
..: :.::::.::::::: :::::::::::::. :::.::::.:..
NP_001 IKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
410 420 430 440 450
>>NP_001112357 (OMIM: 305990) glycine receptor subunit a (452 aa)
initn: 2382 init1: 2009 opt: 2024 Z-score: 2426.0 bits: 458.1 E(85289): 2.2e-128
Smith-Waterman score: 2381; 78.3% identity (88.8% similar) in 457 aa overlap (9-462:10-452)
10 20 30 40 50
pF1KE5 MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDA
: . .:.. . .. ... :... : .::::::::::::::::::
NP_001 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLD
::::::::::::::::::::::::..::::::::::::::.::: :::::::::::::::
NP_001 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 PSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFP
:::::::::::::::::::::::.:::::::::: :::.:::::::::::::::::::::
NP_001 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 MDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGK
:::::: ::::::::::::::::: ...:::::::::::::.:::::.: ::::::::::
NP_001 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 FTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE5 SSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRR--KRKNK
:::::::::::::::::::::::::::::.:::::::::::::::::.::.:: ::.::
NP_001 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE5 TEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKG-PNHPVQVMPKSPDE
: : .:::::.:..:::: :::.::: . :. : .:. ::. :
NP_001 EE--------------DVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDA
370 380 390 400
420 430 440 450 460
pF1KE5 MRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
..: :.::::.::::::: :::::::::::::. :::.::::.:..
NP_001 IKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK
410 420 430 440 450
464 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:26:23 2016 done: Tue Nov 8 01:26:24 2016
Total Scan time: 5.440 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]