Result of FASTA (omim) for
pFN21AE5511
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5511, 408 aa
1>>>pF1KE5511 408 - 408 aa - 408 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3438+/-0.000383; mu= 16.7043+/- 0.024
mean_var=68.3617+/-13.967, 0's: 0 Z-trim(112.6): 73 B-trim: 0 in 0/54
Lambda= 0.155120
statistics sampled from 21532 (21608) to 21532 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.253), width: 16
Scan time: 7.090
The best scores are: opt bits E(85289)
NP_071337 (OMIM: 607367) potassium channel subfami ( 408) 2738 622.0 8.3e-178
NP_071338 (OMIM: 607366) potassium channel subfami ( 430) 1732 396.9 5.1e-110
NP_002237 (OMIM: 603220,615344) potassium channel ( 394) 306 77.7 5.6e-14
XP_011515404 (OMIM: 605874,612292) PREDICTED: pota ( 374) 285 73.0 1.4e-12
NP_001269463 (OMIM: 605874,612292) potassium chann ( 374) 285 73.0 1.4e-12
XP_011515403 (OMIM: 605874,612292) PREDICTED: pota ( 401) 285 73.0 1.5e-12
NP_002236 (OMIM: 601745) potassium channel subfami ( 336) 273 70.3 8.2e-12
NP_066984 (OMIM: 605873) potassium channel subfami ( 538) 259 67.3 1.1e-10
NP_612190 (OMIM: 605873) potassium channel subfami ( 543) 259 67.3 1.1e-10
NP_612191 (OMIM: 605873) potassium channel subfami ( 543) 259 67.3 1.1e-10
NP_001304019 (OMIM: 605720) potassium channel subf ( 393) 257 66.7 1.1e-10
NP_201567 (OMIM: 605720) potassium channel subfami ( 393) 257 66.7 1.1e-10
NP_001128579 (OMIM: 607369) potassium channel subf ( 262) 246 64.2 4.4e-10
XP_016866835 (OMIM: 607369) PREDICTED: potassium c ( 262) 246 64.2 4.4e-10
NP_001128578 (OMIM: 607369) potassium channel subf ( 294) 246 64.2 4.8e-10
NP_115491 (OMIM: 607369) potassium channel subfami ( 309) 246 64.2 5e-10
NP_001128577 (OMIM: 607369) potassium channel subf ( 322) 246 64.2 5.2e-10
XP_011507825 (OMIM: 603219) PREDICTED: potassium c ( 370) 242 63.4 1.1e-09
XP_011507826 (OMIM: 603219) PREDICTED: potassium c ( 370) 242 63.4 1.1e-09
XP_011507824 (OMIM: 603219) PREDICTED: potassium c ( 370) 242 63.4 1.1e-09
NP_055032 (OMIM: 603219) potassium channel subfami ( 411) 242 63.4 1.2e-09
XP_016856738 (OMIM: 603219) PREDICTED: potassium c ( 412) 242 63.4 1.2e-09
NP_001017424 (OMIM: 603219) potassium channel subf ( 422) 242 63.4 1.2e-09
XP_016856737 (OMIM: 603219) PREDICTED: potassium c ( 422) 242 63.4 1.2e-09
NP_001017425 (OMIM: 603219) potassium channel subf ( 426) 242 63.4 1.2e-09
NP_071753 (OMIM: 607368) potassium channel subfami ( 330) 230 60.7 6.3e-09
NP_001128583 (OMIM: 607370) potassium channel subf ( 271) 194 52.5 1.4e-06
NP_113648 (OMIM: 607370) potassium channel subfami ( 332) 194 52.6 1.7e-06
XP_005264350 (OMIM: 603220,615344) PREDICTED: pota ( 284) 193 52.3 1.7e-06
XP_011513237 (OMIM: 607369) PREDICTED: potassium c ( 197) 189 51.3 2.4e-06
NP_004814 (OMIM: 603939) potassium channel subfami ( 313) 191 51.9 2.6e-06
XP_011515405 (OMIM: 605874,612292) PREDICTED: pota ( 291) 186 50.8 5.3e-06
XP_016869020 (OMIM: 605874,612292) PREDICTED: pota ( 264) 184 50.3 6.6e-06
XP_016869019 (OMIM: 605874,612292) PREDICTED: pota ( 264) 184 50.3 6.6e-06
XP_011535142 (OMIM: 605873) PREDICTED: potassium c ( 410) 179 49.3 2.1e-05
XP_011525828 (OMIM: 603939) PREDICTED: potassium c ( 179) 173 47.7 2.6e-05
XP_016883492 (OMIM: 607368) PREDICTED: potassium c ( 218) 159 44.7 0.00027
XP_006715298 (OMIM: 603493) PREDICTED: potassium c ( 317) 156 44.1 0.00059
NP_258416 (OMIM: 603940) potassium channel subfami ( 252) 154 43.6 0.00067
NP_203134 (OMIM: 603940) potassium channel subfami ( 252) 154 43.6 0.00067
NP_005705 (OMIM: 603940) potassium channel subfami ( 257) 154 43.6 0.00068
NP_203133 (OMIM: 603940) potassium channel subfami ( 307) 154 43.6 0.00079
XP_005249513 (OMIM: 603493) PREDICTED: potassium c ( 496) 156 44.2 0.00086
NP_003731 (OMIM: 603493) potassium channel subfami ( 499) 156 44.2 0.00086
>>NP_071337 (OMIM: 607367) potassium channel subfamily K (408 aa)
initn: 2738 init1: 2738 opt: 2738 Z-score: 3313.2 bits: 622.0 E(85289): 8.3e-178
Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 SRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 QCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 GDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGCCP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 QCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANKASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANKASL
310 320 330 340 350 360
370 380 390 400
pF1KE5 AILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR
::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR
370 380 390 400
>>NP_071338 (OMIM: 607366) potassium channel subfamily K (430 aa)
initn: 1794 init1: 1392 opt: 1732 Z-score: 2096.1 bits: 396.9 E(85289): 5.1e-110
Smith-Waterman score: 1732; 65.5% identity (84.5% similar) in 400 aa overlap (12-408:31-430)
10 20 30 40
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSAL
:::::..::.:::::: :::..::.:::::
NP_071 MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ELAHERQAKQRWEERLANFSRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAF
: : .:. :: : ::: .:.... :::.:::::: : ::.:.: .:::::: :::
NP_071 ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 YFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCH
::::::::::::::::::::::: ::: ::: ::..:::::::::::.:...:.::..:.
NP_071 YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 QRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEG
.::::: : :: . .. :.:::::::::::.:.::: ..:.::::::::: .::
NP_071 ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 WSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISI
:.: ::::::::.:::::::::::::.: :..:::::..::.:::.::::::::::::::
NP_071 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI
250 260 270 280 290 300
290 300 310 320 330
pF1KE5 LIKQSLNWILRKMDSGCCPQC--QRGLLRSRRNVVMPGSVRNRCNISIETDGVA-ESDTD
:::: :::.:::.. :: .: : .:::.. ::: : .. .: .: .::..
NP_071 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 GRRLSGEMISMKDLLAANKASLAILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMN
:::::::.:::.:: :.::.:::.::::::: ::: :... . .:.: :::::::..:::
NP_071 GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN
370 380 390 400 410 420
400
pF1KE5 NRLAETSGDR
:::::::..:
NP_071 NRLAETSASR
430
>>NP_002237 (OMIM: 603220,615344) potassium channel subf (394 aa)
initn: 325 init1: 183 opt: 306 Z-score: 372.0 bits: 77.7 E(85289): 5.6e-14
Smith-Waterman score: 450; 31.7% identity (61.7% similar) in 287 aa overlap (13-296:1-258)
10 20 30 40 50 60
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF
....:.: : : . ::: :::::.::: : .:: : : ..
NP_002 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQEL
10 20 30 40
70 80 90 100 110
pF1KE5 SRGHNLSRDELRGFLRHYEEATRAGIRVDNVRP--RWDFTGAFYFVGTVVSTIGFGMTTP
.:::. : ::: :. .:. . .: :.:.:::. ::..:::.: ..:
NP_002 RARYNLSQG---G----YEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 ATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKD
.: :::.: .::.:.: :...:. . ::. :.. :... .. ::. .
NP_002 STDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADV-------
110 120 130 140 150
180 190 200 210 220 230
pF1KE5 AGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTI
:.: .. . .. : ... : ..: .. : :..:.. :.::....::
NP_002 -------SMA----NMVLIGFFSCISTL---CIGAAAFSHYEHWTFFQAYYYCFITLTTI
160 170 180 190 200
240 250 260 270 280 290
pF1KE5 GFGDLVSSQNAH-YESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSG
:::: :. :. . ..: : .::.:: :. : ...:.. .: ...: .: :.
NP_002 GFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV-VLRFMTMNAEDEKRDAE
210 220 230 240 250
300 310 320 330 340 350
pF1KE5 CCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANK
NP_002 HRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSRE
260 270 280 290 300 310
>>XP_011515404 (OMIM: 605874,612292) PREDICTED: potassiu (374 aa)
initn: 358 init1: 166 opt: 285 Z-score: 346.9 bits: 73.0 E(85289): 1.4e-12
Smith-Waterman score: 421; 29.6% identity (61.5% similar) in 270 aa overlap (13-279:1-242)
10 20 30 40 50 60
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF
....:.: : : . ::: :::::.::: :: . ... . . .
XP_011 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRI
10 20 30 40
70 80 90 100 110
pF1KE5 SRGHNLSRDELRGF--LRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTP
. .:.: .. : . . : :::.. : :.:.:::. ::..:::.: ..:
XP_011 KGKYNISSEDYRQLELVILQSEPHRAGVQ-------WKFAGSFYFAITVITTIGYGHAAP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 ATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKD
.: .:: : .::...: :...:. . ::. :.. :..: .. : . .:..
XP_011 GTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVT
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 AGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTI
.: .. : ... : ..: .. : ::.: . :.::....::
XP_011 VG------------------FFSCMGTL---CIGAAAFSQCEEWSFFHAYYYCFITLTTI
170 180 190 200
240 250 260 270 280 290
pF1KE5 GFGDLVSSQN-AHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSG
:::: :. :. . ... :: .:..::.:. : ...:..
XP_011 GFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEE
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE5 CCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANK
XP_011 RASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCTCYRSQDYGGRSVAPQNSFSA
270 280 290 300 310 320
>>NP_001269463 (OMIM: 605874,612292) potassium channel s (374 aa)
initn: 358 init1: 166 opt: 285 Z-score: 346.9 bits: 73.0 E(85289): 1.4e-12
Smith-Waterman score: 421; 29.6% identity (61.5% similar) in 270 aa overlap (13-279:1-242)
10 20 30 40 50 60
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF
....:.: : : . ::: :::::.::: :: . ... . . .
NP_001 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRI
10 20 30 40
70 80 90 100 110
pF1KE5 SRGHNLSRDELRGF--LRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTP
. .:.: .. : . . : :::.. : :.:.:::. ::..:::.: ..:
NP_001 KGKYNISSEDYRQLELVILQSEPHRAGVQ-------WKFAGSFYFAITVITTIGYGHAAP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 ATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKD
.: .:: : .::...: :...:. . ::. :.. :..: .. : . .:..
NP_001 GTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVT
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 AGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTI
.: .. : ... : ..: .. : ::.: . :.::....::
NP_001 VG------------------FFSCMGTL---CIGAAAFSQCEEWSFFHAYYYCFITLTTI
170 180 190 200
240 250 260 270 280 290
pF1KE5 GFGDLVSSQN-AHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSG
:::: :. :. . ... :: .:..::.:. : ...:..
NP_001 GFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEE
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE5 CCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANK
NP_001 RASLAGNRNSMVIHIPEEPRPSRPRYKADVPDLQSVCSCTCYRSQDYGGRSVAPQNSFSA
270 280 290 300 310 320
>>XP_011515403 (OMIM: 605874,612292) PREDICTED: potassiu (401 aa)
initn: 336 init1: 166 opt: 285 Z-score: 346.5 bits: 73.0 E(85289): 1.5e-12
Smith-Waterman score: 423; 27.7% identity (57.1% similar) in 357 aa overlap (13-357:1-323)
10 20 30 40 50 60
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANF
....:.: : : . ::: :::::.::: :: . ... . . .
XP_011 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRI
10 20 30 40
70 80 90 100 110
pF1KE5 SRGHNLSRDELRGF--LRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTP
. .:.: .. : . . : :::.. : :.:.:::. ::..:::.: ..:
XP_011 KGKYNISSEDYRQLELVILQSEPHRAGVQ-------WKFAGSFYFAITVITTIGYGHAAP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 ATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKD
.: .:: : .::...: :...:. . ::. :.. :..: .. : . .:..
XP_011 GTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVT
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 AGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTI
.: .. : ... : ..: .. : ::.: . :.::....::
XP_011 VG------------------FFSCMGTL---CIGAAAFSQCEEWSFFHAYYYCFITLTTI
170 180 190 200
240 250 260 270 280 290
pF1KE5 GFGDLVSSQN-AHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSG
:::: :. :. . ... :: .:..::.:. : ...:.. .: ..: .. :.
XP_011 GFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLV-VLRFLTMNSEDERRDAE
210 220 230 240 250
300 310 320 330 340
pF1KE5 CCPQCQRGLLRSRRNVVM------PGSVRNR---CNISIETDGVAESDTDGRRLSGEMIS
.:. : . :: .. : : : :... . : : :: . :
XP_011 -----ERASLAGNRNSMVIHIPEEPRPSRPRGTNCTFKRGVRGCWVSLPKPNTASGFLPS
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE5 MKDLLAANKASLAILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMNNRLAETSGDR
. :: :..
XP_011 QVDLCCAGRMLYSFPYTTVGMVQLHIDRKPRETLDVRVPASPSGSFGTWPPQSSSTRSRD
320 330 340 350 360 370
>>NP_002236 (OMIM: 601745) potassium channel subfamily K (336 aa)
initn: 357 init1: 181 opt: 273 Z-score: 333.1 bits: 70.3 E(85289): 8.2e-12
Smith-Waterman score: 375; 31.4% identity (63.2% similar) in 258 aa overlap (20-269:25-257)
10 20 30 40 50
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEE
::.:. : :::. ::.:::..:: .: .:. ..
NP_002 MLQSLAGSSCVRLVERHRSAWCFGFLVLGYL--LYLVFGAVVFSSVELPYEDLLRQELRK
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 RLANFSRGHN-LSRDELRGFLRHYEEATRAGIRV-DNVRPRW--DFTGAFYFVGTVVSTI
: . :. ::...:. :: . ::. :. : .:. : :::.:..:..::.::
NP_002 LKRRFLEEHECLSEQQLEQFLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGAL
:.: :.: . ::: : :.:...: :.::.. ..: ::. .. :: .:
NP_002 GYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQR-ITV-----------HVTRRPVL
120 130 140 150 160
180 190 200 210 220
pF1KE5 PQESLKDAGQCEVDSLAGWKPSVYYVMLILCTASILISCC---ASAMYTPIEG-WSYFDS
.. :.. .: .. . . . .:: .:... .: :....:
NP_002 -YFHIR----------WGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSVLEDDWNFLES
170 180 190 200 210
230 240 250 260 270 280
pF1KE5 LYFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSL
.::::...::::.:: : ... . . . ::... ..:.:.
NP_002 FYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVLETFCELHELKK
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE5 NWILRKMDSGCCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMI
NP_002 FRKMFYVKKDKDEDQVHIIEHDQLSFSSITDQAAGMKEDQKQNEPFVATQSSACVDGPAN
280 290 300 310 320 330
>>NP_066984 (OMIM: 605873) potassium channel subfamily K (538 aa)
initn: 329 init1: 167 opt: 259 Z-score: 313.1 bits: 67.3 E(85289): 1.1e-10
Smith-Waterman score: 363; 29.1% identity (60.9% similar) in 261 aa overlap (26-279:78-318)
10 20 30 40 50
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEE
..:.::. :. :: ::: : . :.
NP_066 RATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIAL
50 60 70 80 90 100
60 70 80 90 100 110
pF1KE5 RLANFSRGH-NLSRDELRGFLRHYEEATRAGIR----VDNVRPRWDFTGAFYFVGTVVST
. :.: : : .: .::. ...: .: ::. .: .::. .::.:.:::..:
NP_066 EKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITT
110 120 130 140 150 160
120 130 140 150 160
pF1KE5 IGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQR--QLRRR
::.: .:.: ::::: :.:.. : : .:...: . .. :. . : .. :.
NP_066 IGYGNIAPSTEGGKIFCILYAIFG----IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRK
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE5 GALPQESLKDAGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSL
. : ... : ..:.. .. :.. .... ::::. ..:.
NP_066 KQVSQTKIR----------------VISTILFILAGCIVFVTIPAVIFKYIEGWTALESI
230 240 250 260
230 240 250 260 270 280
pF1KE5 YFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLN
:: :...:.::::.:.. :: . . :. . .::.:. . .....:
NP_066 YFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSK
270 280 290 300 310 320
290 300 310 320 330 340
pF1KE5 WILRKMDSGCCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMIS
NP_066 KTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAH
330 340 350 360 370 380
>>NP_612190 (OMIM: 605873) potassium channel subfamily K (543 aa)
initn: 329 init1: 167 opt: 259 Z-score: 313.1 bits: 67.3 E(85289): 1.1e-10
Smith-Waterman score: 363; 29.1% identity (60.9% similar) in 261 aa overlap (26-279:83-323)
10 20 30 40 50
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEE
..:.::. :. :: ::: : . :.
NP_612 RATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIAL
60 70 80 90 100 110
60 70 80 90 100 110
pF1KE5 RLANFSRGH-NLSRDELRGFLRHYEEATRAGIR----VDNVRPRWDFTGAFYFVGTVVST
. :.: : : .: .::. ...: .: ::. .: .::. .::.:.:::..:
NP_612 EKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITT
120 130 140 150 160 170
120 130 140 150 160
pF1KE5 IGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQR--QLRRR
::.: .:.: ::::: :.:.. : : .:...: . .. :. . : .. :.
NP_612 IGYGNIAPSTEGGKIFCILYAIFG----IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRK
180 190 200 210 220
170 180 190 200 210 220
pF1KE5 GALPQESLKDAGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSL
. : ... : ..:.. .. :.. .... ::::. ..:.
NP_612 KQVSQTKIR----------------VISTILFILAGCIVFVTIPAVIFKYIEGWTALESI
230 240 250 260 270
230 240 250 260 270 280
pF1KE5 YFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLN
:: :...:.::::.:.. :: . . :. . .::.:. . .....:
NP_612 YFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSK
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE5 WILRKMDSGCCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMIS
NP_612 KTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAH
340 350 360 370 380 390
>>NP_612191 (OMIM: 605873) potassium channel subfamily K (543 aa)
initn: 329 init1: 167 opt: 259 Z-score: 313.1 bits: 67.3 E(85289): 1.1e-10
Smith-Waterman score: 363; 29.1% identity (60.9% similar) in 261 aa overlap (26-279:83-323)
10 20 30 40 50
pF1KE5 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEE
..:.::. :. :: ::: : . :.
NP_612 RATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIAL
60 70 80 90 100 110
60 70 80 90 100 110
pF1KE5 RLANFSRGH-NLSRDELRGFLRHYEEATRAGIR----VDNVRPRWDFTGAFYFVGTVVST
. :.: : : .: .::. ...: .: ::. .: .::. .::.:.:::..:
NP_612 EKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITT
120 130 140 150 160 170
120 130 140 150 160
pF1KE5 IGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQR--QLRRR
::.: .:.: ::::: :.:.. : : .:...: . .. :. . : .. :.
NP_612 IGYGNIAPSTEGGKIFCILYAIFG----IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRK
180 190 200 210 220
170 180 190 200 210 220
pF1KE5 GALPQESLKDAGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEGWSYFDSL
. : ... : ..:.. .. :.. .... ::::. ..:.
NP_612 KQVSQTKIR----------------VISTILFILAGCIVFVTIPAVIFKYIEGWTALESI
230 240 250 260 270
230 240 250 260 270 280
pF1KE5 YFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLN
:: :...:.::::.:.. :: . . :. . .::.:. . .....:
NP_612 YFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSK
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE5 WILRKMDSGCCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMIS
NP_612 KTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAH
340 350 360 370 380 390
408 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:21:20 2016 done: Tue Nov 8 01:21:21 2016
Total Scan time: 7.090 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]