Result of FASTA (omim) for
pFN21AE5452
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5452, 351 aa
1>>>pF1KE5452 351 - 351 aa - 351 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8679+/-0.000417; mu= 13.9091+/- 0.026
mean_var=130.2398+/-27.811, 0's: 0 Z-trim(115.2): 295 B-trim: 1273 in 2/53
Lambda= 0.112383
statistics sampled from 25197 (25572) to 25197 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.3), width: 16
Scan time: 6.290
The best scores are: opt bits E(85289)
NP_115737 (OMIM: 606929) THO complex subunit 3 [Ho ( 351) 2440 407.3 2.7e-113
XP_016865474 (OMIM: 606929) PREDICTED: THO complex ( 263) 1840 309.8 4.2e-84
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 338 66.6 1.2e-10
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 338 66.6 1.3e-10
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 311 62.0 2e-09
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 311 62.1 2.2e-09
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 305 61.1 4.4e-09
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 305 61.2 4.7e-09
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 290 58.6 2.1e-08
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 288 58.3 2.7e-08
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 288 58.4 3e-08
XP_011543873 (OMIM: 300196) PREDICTED: F-box-like/ ( 526) 289 58.7 3.3e-08
NP_001132939 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 289 58.7 3.3e-08
NP_001132940 (OMIM: 300196) F-box-like/WD repeat-c ( 526) 289 58.7 3.3e-08
NP_001132938 (OMIM: 300196) F-box-like/WD repeat-c ( 577) 289 58.8 3.6e-08
NP_005638 (OMIM: 300196) F-box-like/WD repeat-cont ( 577) 289 58.8 3.6e-08
NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 279 57.0 9e-08
XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 279 57.1 1e-07
XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 279 57.1 1e-07
NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 279 57.1 1e-07
XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 279 57.1 1e-07
NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 279 57.1 1e-07
XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 279 57.1 1e-07
NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 279 57.1 1e-07
XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 279 57.1 1e-07
XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 279 57.1 1e-07
NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 271 55.8 2.5e-07
NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 271 55.8 2.5e-07
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 271 55.8 2.5e-07
XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536) 271 55.8 2.6e-07
XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 271 55.8 2.6e-07
XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 271 55.8 2.7e-07
XP_016860389 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 267 54.9 2.9e-07
XP_016860390 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 267 54.9 2.9e-07
XP_016860391 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 267 54.9 2.9e-07
XP_011510137 (OMIM: 612173) PREDICTED: sperm-assoc ( 323) 267 54.9 2.9e-07
XP_016860387 (OMIM: 612173) PREDICTED: sperm-assoc ( 390) 267 55.0 3.3e-07
XP_016860385 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 267 55.1 3.9e-07
XP_016860386 (OMIM: 612173) PREDICTED: sperm-assoc ( 512) 267 55.1 3.9e-07
XP_011510124 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 267 55.1 4e-07
XP_011510125 (OMIM: 612173) PREDICTED: sperm-assoc ( 528) 267 55.1 4e-07
XP_011510123 (OMIM: 612173) PREDICTED: sperm-assoc ( 537) 267 55.1 4e-07
XP_011510121 (OMIM: 612173) PREDICTED: sperm-assoc ( 577) 267 55.2 4.2e-07
XP_011510116 (OMIM: 612173) PREDICTED: sperm-assoc ( 600) 267 55.2 4.3e-07
NP_078808 (OMIM: 612173) sperm-associated antigen ( 631) 267 55.2 4.5e-07
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 259 53.9 1.1e-06
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 259 53.9 1.1e-06
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 259 53.9 1.1e-06
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 259 54.0 1.1e-06
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 259 54.0 1.1e-06
>>NP_115737 (OMIM: 606929) THO complex subunit 3 [Homo s (351 aa)
initn: 2440 init1: 2440 opt: 2440 Z-score: 2155.1 bits: 407.3 E(85289): 2.7e-113
Smith-Waterman score: 2440; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KE5 MAVPAAAMGPSALGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MAVPAAAMGPSALGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DKTIRIWDVRTTKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DKTIRIWDVRTTKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 FKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 FKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 TGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDK
250 260 270 280 290 300
310 320 330 340 350
pF1KE5 LWEVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LWEVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
310 320 330 340 350
>>XP_016865474 (OMIM: 606929) PREDICTED: THO complex sub (263 aa)
initn: 1840 init1: 1840 opt: 1840 Z-score: 1630.9 bits: 309.8 E(85289): 4.2e-84
Smith-Waterman score: 1840; 99.6% identity (100.0% similar) in 263 aa overlap (89-351:1-263)
60 70 80 90 100 110
pF1KE5 HSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTA
.:::::::::::::::::::::::::::::
XP_016 MVKENNYRGHGDSVDQLCWHPSNPDLFVTA
10 20 30
120 130 140 150 160 170
pF1KE5 SGDKTIRIWDVRTTKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGDKTIRIWDVRTTKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE5 EQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKY
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE5 FATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETG
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE5 DKLWEVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKLWEVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
220 230 240 250 260
>>NP_001186706 (OMIM: 614784,615973) POC1 centriolar pro (436 aa)
initn: 374 init1: 128 opt: 338 Z-score: 312.1 bits: 66.6 E(85289): 1.2e-10
Smith-Waterman score: 338; 29.9% identity (61.9% similar) in 278 aa overlap (43-309:50-317)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
:: : :: ::.: :.:: .: ::. ::.
NP_001 VVTSVQFSPHGNLLASASRDRTVRLWIPDKRG--KFSEFKAHTAPVRSVDFSADGQFLAT
20 30 40 50 60 70
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: ::. .:. . ..:.. . :: : : : . : :: :.:. : ::::.:::.
NP_001 ASEDKSIKVWSMYRQRFLY-SLYR-HTHWVR--CAKFS-PDGRLIVSCSEDKTIKIWDTT
80 90 100 110 120 130
140 150 160 170 180
pF1KE5 TTKCIATV-NTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .. : . ..:.: :: ...:..: :..... . : . :: :
NP_001 NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCI
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ....: ..::. : . . ....: . . ..:. :. ::.:.::. :
NP_001 SFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE5 SLW--DVDELVCVRCFSRLDWPVRTLSFSHDGKML---ASASEDHFIDIAEVETGDKLW-
:: . ::: : . ... . .. : :. ..: . . : . :: . ::
NP_001 LLWRTNFDELHC-KGLTKRN--LKRLHFDSPPHLLDIYPRTPHPHEEKVETVEINPKLEV
260 270 280 290 300
310 320 330 340 350
pF1KE5 -EVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
..: .:
NP_001 IDLQISTPPVMDILSFDSTTTTETSGRTLPDKGEEACGYFLNPSLMSPECLPTTTKKKTE
310 320 330 340 350 360
>>NP_758440 (OMIM: 614784,615973) POC1 centriolar protei (478 aa)
initn: 402 init1: 128 opt: 338 Z-score: 311.7 bits: 66.6 E(85289): 1.3e-10
Smith-Waterman score: 338; 29.9% identity (61.9% similar) in 278 aa overlap (43-309:92-359)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
:: : :: ::.: :.:: .: ::. ::.
NP_758 VVTSVQFSPHGNLLASASRDRTVRLWIPDKRG--KFSEFKAHTAPVRSVDFSADGQFLAT
70 80 90 100 110
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: ::. .:. . ..:.. . :: : : : . : :: :.:. : ::::.:::.
NP_758 ASEDKSIKVWSMYRQRFLY-SLYR-HTHWVR--CAKFS-PDGRLIVSCSEDKTIKIWDTT
120 130 140 150 160 170
140 150 160 170 180
pF1KE5 TTKCIATV-NTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .. : . ..:.: :: ...:..: :..... . : . :: :
NP_758 NKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCI
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ....: ..::. : . . ....: . . ..:. :. ::.:.::. :
NP_758 SFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQV
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE5 SLW--DVDELVCVRCFSRLDWPVRTLSFSHDGKML---ASASEDHFIDIAEVETGDKLW-
:: . ::: : . ... . .. : :. ..: . . : . :: . ::
NP_758 LLWRTNFDELHC-KGLTKRN--LKRLHFDSPPHLLDIYPRTPHPHEEKVETVEINPKLEV
300 310 320 330 340 350
310 320 330 340 350
pF1KE5 -EVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
..: .:
NP_758 IDLQISTPPVMDILSFDSTTTTETSGRTLPDKGEEACGYFLNPSLMSPECLPTTTKKKTE
360 370 380 390 400 410
>>XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 cen (321 aa)
initn: 232 init1: 87 opt: 311 Z-score: 290.0 bits: 62.0 E(85289): 2e-09
Smith-Waterman score: 311; 27.9% identity (62.1% similar) in 269 aa overlap (43-306:55-308)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
.:.: . : ::.: :.:: . ::. ...
XP_016 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: :::..:. ...... . : . : : . : :: :.:.:: :::...::
XP_016 ASDDKTVKVWATHRQKFLF--SLSQHINWVR--CAKFS-PDGRLIVSASDDKTVKLWDKS
90 100 110 120 130
140 150 160 170 180
pF1KE5 TTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .: .. . . :.: ::... :..: :..::: . :.. :: .
XP_016 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGL
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ..... ..::. : . . ....: . . :. :.:::.:..: :
XP_016 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE5 SLWDVD-ELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCE
.: . ..: ... : ::. : :.. .: :... . : ::: ::
XP_016 MVWKSNFDIVDHGEVTKVPRPPATLASSM-GNLTVSILEQRL-----TLTEDKL--KQCL
260 270 280 290 300
310 320 330 340 350
pF1KE5 SPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
XP_016 ENQQLIMQRATP
310 320
>>NP_001155052 (OMIM: 614783,614813) POC1 centriolar pro (359 aa)
initn: 232 init1: 87 opt: 311 Z-score: 289.5 bits: 62.1 E(85289): 2.2e-09
Smith-Waterman score: 311; 27.9% identity (62.1% similar) in 269 aa overlap (43-306:93-346)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
.:.: . : ::.: :.:: . ::. ...
NP_001 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: :::..:. ...... . : . : : . : :: :.:.:: :::...::
NP_001 ASDDKTVKVWATHRQKFLF--SLSQHINWVR--CAKFS-PDGRLIVSASDDKTVKLWDKS
130 140 150 160 170
140 150 160 170 180
pF1KE5 TTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .: .. . . :.: ::... :..: :..::: . :.. :: .
NP_001 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGL
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ..... ..::. : . . ....: . . :. :.:::.:..: :
NP_001 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE5 SLWDVD-ELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCE
.: . ..: ... : ::. : :.. .: :... . : ::: ::
NP_001 MVWKSNFDIVDHGEVTKVPRPPATLASSM-GNLTVSILEQRL-----TLTEDKL--KQCL
300 310 320 330 340
310 320 330 340 350
pF1KE5 SPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
NP_001 ENQQLIMQRATP
350
>>NP_001155053 (OMIM: 614783,614813) POC1 centriolar pro (369 aa)
initn: 232 init1: 87 opt: 305 Z-score: 284.1 bits: 61.1 E(85289): 4.4e-09
Smith-Waterman score: 305; 27.7% identity (63.4% similar) in 238 aa overlap (43-275:55-285)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
.:.: . : ::.: :.:: . ::. ...
NP_001 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT
30 40 50 60 70 80
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: :::..:. ...... . : . : : . : :: :.:.:: :::...::
NP_001 ASDDKTVKVWATHRQKFL--FSLSQHINWVR--CAKFS-PDGRLIVSASDDKTVKLWDKS
90 100 110 120 130
140 150 160 170 180
pF1KE5 TTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .: .. . . :.: ::... :..: :..::: . :.. :: .
NP_001 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGL
140 150 160 170 180 190
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ..... ..::. : . . ....: . . :. :.:::.:..: :
NP_001 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE5 SLWDVD-ELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCE
.: . ..: ... : ::. :
NP_001 MVWKSNFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSV
260 270 280 290 300 310
>>NP_056241 (OMIM: 614783,614813) POC1 centriolar protei (407 aa)
initn: 232 init1: 87 opt: 305 Z-score: 283.6 bits: 61.2 E(85289): 4.7e-09
Smith-Waterman score: 305; 27.7% identity (63.4% similar) in 238 aa overlap (43-275:93-323)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
.:.: . : ::.: :.:: . ::. ...
NP_056 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: :::..:. ...... . : . : : . : :: :.:.:: :::...::
NP_056 ASDDKTVKVWATHRQKFL--FSLSQHINWVR--CAKFS-PDGRLIVSASDDKTVKLWDKS
130 140 150 160 170
140 150 160 170 180
pF1KE5 TTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .: .. . . :.: ::... :..: :..::: . :.. :: .
NP_056 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGL
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ..... ..::. : . . ....: . . :. :.:::.:..: :
NP_056 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQV
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE5 SLWDVD-ELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCE
.: . ..: ... : ::. :
NP_056 MVWKSNFDIVDHGEVTKVPRPPATLASSMGNLPEVDFPVPPGRGRSVESVQSQPQEPVSV
300 310 320 330 340 350
>>XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 cen (300 aa)
initn: 232 init1: 87 opt: 290 Z-score: 272.0 bits: 58.6 E(85289): 2.1e-08
Smith-Waterman score: 291; 27.5% identity (64.4% similar) in 222 aa overlap (43-260:93-299)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
.:.: . : ::.: :.:: . ::. ...
XP_011 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: :::..:. ...... . : . : : . : :: :.:.:: :::...::
XP_011 ASDDKTVKVWATHRQKFL--FSLSQHINWVR--CAKFS-PDGRLIVSASDDKTVKLWDKS
130 140 150 160 170
140 150 160 170 180
pF1KE5 TTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .: .. . . :.: ::... :..: :..::: . :.. :: .
XP_011 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGL
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ..... ..::. : . . ....: . . :. :.:::.:..:
XP_011 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSD---
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE5 SLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCES
....:.:
XP_011 -----EQVICARP
300
>>XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 cen (326 aa)
initn: 232 init1: 87 opt: 288 Z-score: 269.8 bits: 58.3 E(85289): 2.7e-08
Smith-Waterman score: 288; 28.5% identity (65.7% similar) in 207 aa overlap (43-245:93-292)
20 30 40 50 60 70
pF1KE5 LGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLAS
.:.: . : ::.: :.:: . ::. ...
XP_011 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE5 GSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPD--LFVTASGDKTIRIWDVR
.: :::..:. ...... . : . : : . : :: :.:.:: :::...::
XP_011 ASDDKTVKVWATHRQKFL--FSLSQHINWVR--CAKFS-PDGRLIVSASDDKTVKLWDKS
130 140 150 160 170
140 150 160 170 180
pF1KE5 TTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFE-VNEI
. .:. . .: .. . . :.: ::... :..: :..::: . :.. :: .
XP_011 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGL
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE5 SWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALV
:.. ..:... ..... ..::. : . . ....: . . :. :.:::.:..:
XP_011 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQT
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE5 SLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCES
XP_011 VSILEQRLTLTEDKLKQCLENQQLIMQRATP
300 310 320
351 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:54:21 2016 done: Tue Nov 8 00:54:22 2016
Total Scan time: 6.290 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]