FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5451, 350 aa
  1>>>pF1KE5451 350 - 350 aa - 350 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3593+/-0.000844; mu= 16.7210+/- 0.051
 mean_var=75.6037+/-14.712, 0's: 0 Z-trim(107.5): 16  B-trim: 0 in 0/53
 Lambda= 0.147504
 statistics sampled from 9611 (9616) to 9611 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.295), width:  16
 Scan time:  2.400

The best scores are:                                      opt bits E(32554)
CCDS3620.1 NUDT9 gene_id:53343|Hs108|chr4          ( 350) 2371 513.8 8.5e-146
CCDS3621.1 NUDT9 gene_id:53343|Hs108|chr4          ( 300) 2059 447.4 7.3e-126
CCDS13710.1 TRPM2 gene_id:7226|Hs108|chr21         (1503)  388 92.3 2.9e-18
CCDS82681.1 TRPM2 gene_id:7226|Hs108|chr21         (1553)  388 92.3   3e-18


>>CCDS3620.1 NUDT9 gene_id:53343|Hs108|chr4               (350 aa)
 initn: 2371 init1: 2371 opt: 2371  Z-score: 2731.0  bits: 513.8 E(32554): 8.5e-146
Smith-Waterman score: 2371; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)

               10        20        30        40        50        60
pF1KE5 MAGRLLGKALAAVSLSLALASVTIRSSRCRGIQAFRNSFSSSWFHLNTNVMSGSNGSKEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 MAGRLLGKALAAVSLSLALASVTIRSSRCRGIQAFRNSFSSSWFHLNTNVMSGSNGSKEN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 SHNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 SHNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE5 DSSGNKIMHPVSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 DSSGNKIMHPVSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE5 KTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 KTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLML
              250       260       270       280       290       300

              310       320       330       340       350
pF1KE5 EAGDDAGKVKWVDINDKLKLYASHSQFIKLVAEKRDAHWSEDSEADCHAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 EAGDDAGKVKWVDINDKLKLYASHSQFIKLVAEKRDAHWSEDSEADCHAL
              310       320       330       340       350

>>CCDS3621.1 NUDT9 gene_id:53343|Hs108|chr4               (300 aa)
 initn: 2059 init1: 2059 opt: 2059  Z-score: 2373.1  bits: 447.4 E(32554): 7.3e-126
Smith-Waterman score: 2059; 100.0% identity (100.0% similar) in 300 aa overlap (51-350:1-300)

               30        40        50        60        70        80
pF1KE5 SVTIRSSRCRGIQAFRNSFSSSWFHLNTNVMSGSNGSKENSHNKARTSPYPGSKVERSQV
                                     ::::::::::::::::::::::::::::::
CCDS36                               MSGSNGSKENSHNKARTSPYPGSKVERSQV
                                             10        20        30

               90       100       110       120       130       140
pF1KE5 PNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNFSPKFNEKDGHVERKSKNGLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 PNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNFSPKFNEKDGHVERKSKNGLY
               40        50        60        70        80        90

              150       160       170       180       190       200
pF1KE5 EIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKRDSSGNKIMHPVSGKHILQFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 EIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKRDSSGNKIMHPVSGKHILQFV
              100       110       120       130       140       150

              210       220       230       240       250       260
pF1KE5 AIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQKTSAEKREIEEKLHKLFSQD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 AIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQKTSAEKREIEEKLHKLFSQD
              160       170       180       190       200       210

              270       280       290       300       310       320
pF1KE5 HLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLMLEAGDDAGKVKWVDINDKLKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 HLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLMLEAGDDAGKVKWVDINDKLKL
              220       230       240       250       260       270

              330       340       350
pF1KE5 YASHSQFIKLVAEKRDAHWSEDSEADCHAL
       ::::::::::::::::::::::::::::::
CCDS36 YASHSQFIKLVAEKRDAHWSEDSEADCHAL
              280       290       300

>>CCDS13710.1 TRPM2 gene_id:7226|Hs108|chr21              (1503 aa)
 initn: 520 init1: 296 opt: 388  Z-score: 441.4  bits: 92.3 E(32554): 2.9e-18
Smith-Waterman score: 558; 36.6% identity (60.6% similar) in 287 aa overlap (59-339:1236-1503)

       30        40        50        60        70        80        
pF1KE5 CRGIQAFRNSFSSSWFHLNTNVMSGSNGSKENSHNKARTSPYPGSKVERSQVPNEKVGWL
                                     .. : .::   ::.  : :  :::::: : 
CCDS13 EADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNEKVPWE
        1210      1220      1230      1240      1250      1260     

       90       100       110         120       130       140      
pF1KE5 VEWQDYKPVEYTAVSVLAGPRWADPQIS--ESNFSPKFNEKDGHVERKSKNGLYEIENGR
       .:.  : :  :::    :.    ::. .  :   . ..:  ::  .:.: .: : .. : 
CCDS13 TEFLIYDPPFYTAERKDAAA--MDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQAGL
        1270      1280        1290      1300      1310      1320   

        150       160       170       180       190       200      
pF1KE5 PRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKRDSSGNKIMHPVSGKHILQFVAIKRKD
       : :: ::::: ::: :. .::::.  :..:::.:. .:    . .  :..:. ...:   
CCDS13 PLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSI--KKMLEVLVVKLPL
          1330      1340      1350      1360        1370      1380 

        210       220       230       240       250       260      
pF1KE5 CGEWAIPGGMVDPGEKISATLKREFGEEALNSLQKTSAEKREIEEKLHKLFSQDHLVIYK
         .::.:::  .::: .   ::: . .:   :.           :.: :      . .::
CCDS13 SEHWALPGGSREPGEMLPRKLKRILRQEHWPSF-----------ENLLKC----GMEVYK
            1390      1400      1410                 1420          

        270       280         290         300       310       320  
pF1KE5 GYVDDPRNTDNAWMETEAVNYH--DETGEIMDNLM--LEAGDDAGKVKWVDINDKLKLYA
       ::.::::::::::.:: ::. :  :..   .. :   :.: :......:  .. .. :::
CCDS13 GYMDDPRNTDNAWIETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYA
       1430      1440      1450      1460      1470      1480      

            330       340       350
pF1KE5 SHSQFIKLVAEKRDAHWSEDSEADCHAL
       .:. ... .: .  ::.           
CCDS13 NHKTLLQKAAAEFGAHY           
       1490      1500              

>>CCDS82681.1 TRPM2 gene_id:7226|Hs108|chr21              (1553 aa)
 initn: 520 init1: 296 opt: 388  Z-score: 441.2  bits: 92.3 E(32554): 3e-18
Smith-Waterman score: 558; 36.6% identity (60.6% similar) in 287 aa overlap (59-339:1286-1553)

       30        40        50        60        70        80        
pF1KE5 CRGIQAFRNSFSSSWFHLNTNVMSGSNGSKENSHNKARTSPYPGSKVERSQVPNEKVGWL
                                     .. : .::   ::.  : :  :::::: : 
CCDS82 EADVPTLASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNEKVPWE
        1260      1270      1280      1290      1300      1310     

       90       100       110         120       130       140      
pF1KE5 VEWQDYKPVEYTAVSVLAGPRWADPQIS--ESNFSPKFNEKDGHVERKSKNGLYEIENGR
       .:.  : :  :::    :.    ::. .  :   . ..:  ::  .:.: .: : .. : 
CCDS82 TEFLIYDPPFYTAERKDAAA--MDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQAGL
        1320      1330        1340      1350      1360      1370   

        150       160       170       180       190       200      
pF1KE5 PRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKRDSSGNKIMHPVSGKHILQFVAIKRKD
       : :: ::::: ::: :. .::::.  :..:::.:. .:    . .  :..:. ...:   
CCDS82 PLNPMGRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSI--KKMLEVLVVKLPL
          1380      1390      1400      1410        1420      1430 

        210       220       230       240       250       260      
pF1KE5 CGEWAIPGGMVDPGEKISATLKREFGEEALNSLQKTSAEKREIEEKLHKLFSQDHLVIYK
         .::.:::  .::: .   ::: . .:   :.           :.: :      . .::
CCDS82 SEHWALPGGSREPGEMLPRKLKRILRQEHWPSF-----------ENLLKC----GMEVYK
            1440      1450      1460                 1470          

        270       280         290         300       310       320  
pF1KE5 GYVDDPRNTDNAWMETEAVNYH--DETGEIMDNLM--LEAGDDAGKVKWVDINDKLKLYA
       ::.::::::::::.:: ::. :  :..   .. :   :.: :......:  .. .. :::
CCDS82 GYMDDPRNTDNAWIETVAVSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYA
       1480      1490      1500      1510      1520      1530      

            330       340       350
pF1KE5 SHSQFIKLVAEKRDAHWSEDSEADCHAL
       .:. ... .: .  ::.           
CCDS82 NHKTLLQKAAAEFGAHY           
       1540      1550              




350 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 00:53:47 2016 done: Tue Nov  8 00:53:47 2016
 Total Scan time:  2.400 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]