Result of FASTA (omim) for
pFN21AE5446
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5446, 322 aa
1>>>pF1KE5446 322 - 322 aa - 322 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6413+/-0.000342; mu= 10.0222+/- 0.021
mean_var=118.4808+/-25.192, 0's: 0 Z-trim(118.0): 54 B-trim: 1423 in 2/47
Lambda= 0.117828
statistics sampled from 30371 (30437) to 30371 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.357), width: 16
Scan time: 7.460
The best scores are: opt bits E(85289)
NP_001128577 (OMIM: 607369) potassium channel subf ( 322) 2256 394.3 1.8e-109
XP_016866835 (OMIM: 607369) PREDICTED: potassium c ( 262) 1499 265.5 8.5e-71
NP_001128579 (OMIM: 607369) potassium channel subf ( 262) 1499 265.5 8.5e-71
NP_001128578 (OMIM: 607369) potassium channel subf ( 294) 1499 265.5 9.3e-71
NP_115491 (OMIM: 607369) potassium channel subfami ( 309) 1499 265.6 9.7e-71
XP_011513237 (OMIM: 607369) PREDICTED: potassium c ( 197) 1047 188.6 9.2e-48
NP_113648 (OMIM: 607370) potassium channel subfami ( 332) 641 119.7 8.3e-27
NP_001128583 (OMIM: 607370) potassium channel subf ( 271) 632 118.1 2e-26
NP_066984 (OMIM: 605873) potassium channel subfami ( 538) 600 112.9 1.5e-24
NP_612191 (OMIM: 605873) potassium channel subfami ( 543) 600 112.9 1.5e-24
NP_612190 (OMIM: 605873) potassium channel subfami ( 543) 600 112.9 1.5e-24
XP_011507825 (OMIM: 603219) PREDICTED: potassium c ( 370) 590 111.1 3.7e-24
XP_011507826 (OMIM: 603219) PREDICTED: potassium c ( 370) 590 111.1 3.7e-24
XP_011507824 (OMIM: 603219) PREDICTED: potassium c ( 370) 590 111.1 3.7e-24
NP_055032 (OMIM: 603219) potassium channel subfami ( 411) 590 111.1 4e-24
XP_016856738 (OMIM: 603219) PREDICTED: potassium c ( 412) 590 111.1 4e-24
NP_001017424 (OMIM: 603219) potassium channel subf ( 422) 590 111.1 4.1e-24
XP_016856737 (OMIM: 603219) PREDICTED: potassium c ( 422) 590 111.1 4.1e-24
NP_001017425 (OMIM: 603219) potassium channel subf ( 426) 590 111.1 4.1e-24
XP_005249513 (OMIM: 603493) PREDICTED: potassium c ( 496) 553 104.9 3.6e-22
NP_201567 (OMIM: 605720) potassium channel subfami ( 393) 546 103.6 6.9e-22
NP_001304019 (OMIM: 605720) potassium channel subf ( 393) 546 103.6 6.9e-22
NP_003731 (OMIM: 603493) potassium channel subfami ( 499) 545 103.5 9.3e-22
NP_002236 (OMIM: 601745) potassium channel subfami ( 336) 488 93.7 5.6e-19
XP_011535142 (OMIM: 605873) PREDICTED: potassium c ( 410) 481 92.6 1.5e-18
NP_004814 (OMIM: 603939) potassium channel subfami ( 313) 452 87.6 3.7e-17
NP_258416 (OMIM: 603940) potassium channel subfami ( 252) 364 72.6 1e-12
NP_203134 (OMIM: 603940) potassium channel subfami ( 252) 364 72.6 1e-12
NP_005705 (OMIM: 603940) potassium channel subfami ( 257) 364 72.6 1e-12
NP_203133 (OMIM: 603940) potassium channel subfami ( 307) 364 72.6 1.2e-12
NP_002237 (OMIM: 603220,615344) potassium channel ( 394) 362 72.4 1.8e-12
XP_011515404 (OMIM: 605874,612292) PREDICTED: pota ( 374) 353 70.8 5e-12
NP_001269463 (OMIM: 605874,612292) potassium chann ( 374) 353 70.8 5e-12
XP_011515403 (OMIM: 605874,612292) PREDICTED: pota ( 401) 353 70.8 5.2e-12
NP_071753 (OMIM: 607368) potassium channel subfami ( 330) 343 69.1 1.5e-11
XP_011542486 (OMIM: 601745) PREDICTED: potassium c ( 268) 263 55.4 1.5e-07
NP_071337 (OMIM: 607367) potassium channel subfami ( 408) 246 52.7 1.6e-06
NP_071338 (OMIM: 607366) potassium channel subfami ( 430) 245 52.5 1.9e-06
NP_862823 (OMIM: 613655,613656) potassium channel ( 384) 225 49.1 1.8e-05
XP_005264350 (OMIM: 603220,615344) PREDICTED: pota ( 284) 200 44.7 0.00027
XP_016869019 (OMIM: 605874,612292) PREDICTED: pota ( 264) 195 43.8 0.00046
XP_016869020 (OMIM: 605874,612292) PREDICTED: pota ( 264) 195 43.8 0.00046
XP_011515405 (OMIM: 605874,612292) PREDICTED: pota ( 291) 195 43.9 0.0005
XP_011525829 (OMIM: 603939) PREDICTED: potassium c ( 176) 191 43.0 0.00054
XP_016882995 (OMIM: 603939) PREDICTED: potassium c ( 185) 191 43.1 0.00056
XP_011525828 (OMIM: 603939) PREDICTED: potassium c ( 179) 188 42.5 0.00077
>>NP_001128577 (OMIM: 607369) potassium channel subfamil (322 aa)
initn: 2256 init1: 2256 opt: 2256 Z-score: 2086.2 bits: 394.3 E(85289): 1.8e-109
Smith-Waterman score: 2256; 100.0% identity (100.0% similar) in 322 aa overlap (1-322:1-322)
10 20 30 40 50 60
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFITPSGLLPSQEPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFITPSGLLPSQEPFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQERFRPLHPGAWKFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQERFRPLHPGAWKFW
250 260 270 280 290 300
310 320
pF1KE5 PLPLPSSNSKWAPMWLGSSAQV
::::::::::::::::::::::
NP_001 PLPLPSSNSKWAPMWLGSSAQV
310 320
>>XP_016866835 (OMIM: 607369) PREDICTED: potassium chann (262 aa)
initn: 1499 init1: 1499 opt: 1499 Z-score: 1392.0 bits: 265.5 E(85289): 8.5e-71
Smith-Waterman score: 1499; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFITPSGLLPSQEPFQ
:::::::::::::::::::::::::::::::::::::::::
XP_016 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGLRQGCGAKAAPGRRPRRGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQERFRPLHPGAWKFW
XP_016 TAARGVQVTPQDFPISKKGLGS
250 260
>>NP_001128579 (OMIM: 607369) potassium channel subfamil (262 aa)
initn: 1499 init1: 1499 opt: 1499 Z-score: 1392.0 bits: 265.5 E(85289): 8.5e-71
Smith-Waterman score: 1499; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFITPSGLLPSQEPFQ
:::::::::::::::::::::::::::::::::::::::::
NP_001 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGLRQGCGAKAAPGRRPRRGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQERFRPLHPGAWKFW
NP_001 TAARGVQVTPQDFPISKKGLGS
250 260
>>NP_001128578 (OMIM: 607369) potassium channel subfamil (294 aa)
initn: 1499 init1: 1499 opt: 1499 Z-score: 1391.3 bits: 265.5 E(85289): 9.3e-71
Smith-Waterman score: 1499; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFITPSGLLPSQEPFQ
:::::::::::::::::::::::::::::::::::::::::
NP_001 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQERFRPLHPGAWKFW
NP_001 LLGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPRPQKIPISA
250 260 270 280 290
>>NP_115491 (OMIM: 607369) potassium channel subfamily K (309 aa)
initn: 1499 init1: 1499 opt: 1499 Z-score: 1391.0 bits: 265.6 E(85289): 9.7e-71
Smith-Waterman score: 1499; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFITPSGLLPSQEPFQ
:::::::::::::::::::::::::::::::::::::::::
NP_115 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 TPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQERFRPLHPGAWKFW
NP_115 LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF
250 260 270 280 290 300
>>XP_011513237 (OMIM: 607369) PREDICTED: potassium chann (197 aa)
initn: 1064 init1: 1047 opt: 1047 Z-score: 978.5 bits: 188.6 E(85289): 9.2e-48
Smith-Waterman score: 1047; 100.0% identity (100.0% similar) in 156 aa overlap (66-221:1-156)
40 50 60 70 80 90
pF1KE5 ERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDF
::::::::::::::::::::::::::::::
XP_011 MEQFVQVIMEAWVKGVNPKGNSTNPSNWDF
10 20 30
100 110 120 130 140 150
pF1KE5 GSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE5 RWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGF
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE5 GDYVVGHPLNFITPSGLLPSQEPFQTPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLA
::::::
XP_011 GDYVVGLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDFPISKKGLGS
160 170 180 190
>>NP_113648 (OMIM: 607370) potassium channel subfamily K (332 aa)
initn: 639 init1: 406 opt: 641 Z-score: 602.3 bits: 119.7 E(85289): 8.3e-27
Smith-Waterman score: 645; 37.4% identity (67.4% similar) in 313 aa overlap (2-309:10-302)
10 20 30 40 50
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKL
: . . .: .. :::::. :: ::. .: :: .: .: .:: .:
NP_113 MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYG
..:.:.::::. :...... ...:. .:.. .:.:. . :.. .::::. ...::::::
NP_113 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
70 80 90 100 110 120
120 130 140 150 160
pF1KE5 NLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRA---HLAAIE--RWEDRPRRSQVL
::.:.: :...::.:.::.:::::.. ::.:: .. : :. :.: : ... :
NP_113 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQD-PDKARWL
130 140 150 160 170
170 180 190 200 210 220
pF1KE5 QVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFI
: . .:. : :..:..::..:::.::::..::::::::::::.::::::.: .:
NP_113 A--GSGALLS-GLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIG--MN--
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 TPSGLLPSQEPFQTPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQE
:::. . . . : : .. .. . :: ...:: . :. ..:
NP_113 ------PSQR-YPLWYKNMVSLWILFGMAWLALIIKLILSQLETPGRVCSC--CHHSSKE
240 250 260 270 280
290 300 310 320
pF1KE5 RFRPLHPGAWKFWPLPLPSSNSKWAPMWLGSSAQV
:. .:. : : :.:
NP_113 DFKS---QSWRQGPDREPESHSPQQGCYPEGPMGIIQHLEPSAHAAGCGKDS
290 300 310 320 330
>>NP_001128583 (OMIM: 607370) potassium channel subfamil (271 aa)
initn: 631 init1: 406 opt: 632 Z-score: 595.3 bits: 118.1 E(85289): 2e-26
Smith-Waterman score: 632; 43.8% identity (76.3% similar) in 224 aa overlap (2-220:10-229)
10 20 30 40 50
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKL
: . . .: .. :::::. :: ::. .: :: .: .: .:: .:
NP_001 MYRPRARAAPEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYG
..:.:.::::. :...... ...:. .:.. .:.:. . :.. .::::. ...::::::
NP_001 ELLQNFTCLDRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYG
70 80 90 100 110 120
120 130 140 150 160
pF1KE5 NLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRA---HLAAIE--RWEDRPRRSQVL
::.:.: :...::.:.::.:::::.. ::.:: .. : :. :.: : ... :
NP_001 NLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLMQQGVNHWASRLGGTWQD-PDKARWL
130 140 150 160 170
170 180 190 200 210 220
pF1KE5 QVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHPLNFI
: . .:. : :..:..::..:::.::::..::::::::::::.::::::.
NP_001 A--GSGALLS-GLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIASCLISD
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 TPSGLLPSQEPFQTPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFPLPDCNIPDQE
NP_001 TRKPNRDWQTLERTSKSSGGLLKYRFLAGHGGSHL
240 250 260 270
>>NP_066984 (OMIM: 605873) potassium channel subfamily K (538 aa)
initn: 445 init1: 277 opt: 600 Z-score: 561.7 bits: 112.9 E(85289): 1.5e-24
Smith-Waterman score: 600; 41.1% identity (76.6% similar) in 214 aa overlap (14-221:72-285)
10 20 30 40
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQS
:. .... : ::. :. .:. ::. :...
NP_066 RLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQ
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE5 RDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTN-PSNWDFGSSFFFA
.. . ::: .::....:.. .: ..: ..: ::.: :::.: :.::.::.::::
NP_066 KNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFA
110 120 130 140 150 160
110 120 130 140 150
pF1KE5 GTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFL----NHLGTGLRAHLAAIERWE
:::.:::::::.:::::.:..::..::..:::: ..: ..::: . .: .:.
NP_066 GTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVF
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE5 DRPRRSQV-LQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGD
. . ::. ..:.. ::. : .:.. .: ..:...:::. :..::. .::.:.::::
NP_066 RKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGD
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE5 YVVGHPLNFITPSGLLPSQEPFQTPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFP
.:.:
NP_066 FVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAA
290 300 310 320 330 340
>>NP_612191 (OMIM: 605873) potassium channel subfamily K (543 aa)
initn: 445 init1: 277 opt: 600 Z-score: 561.6 bits: 112.9 E(85289): 1.5e-24
Smith-Waterman score: 600; 41.1% identity (76.6% similar) in 214 aa overlap (14-221:77-290)
10 20 30 40
pF1KE5 MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQS
:. .... : ::. :. .:. ::. :...
NP_612 RLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQ
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE5 RDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTN-PSNWDFGSSFFFA
.. . ::: .::....:.. .: ..: ..: ::.: :::.: :.::.::.::::
NP_612 KNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFA
110 120 130 140 150 160
110 120 130 140 150
pF1KE5 GTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFL----NHLGTGLRAHLAAIERWE
:::.:::::::.:::::.:..::..::..:::: ..: ..::: . .: .:.
NP_612 GTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVF
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE5 DRPRRSQV-LQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGD
. . ::. ..:.. ::. : .:.. .: ..:...:::. :..::. .::.:.::::
NP_612 RKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGD
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE5 YVVGHPLNFITPSGLLPSQEPFQTPHGKPESQQIPGSFQKVSSMNVWPLSGMHSPGLAFP
.:.:
NP_612 FVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAA
290 300 310 320 330 340
322 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:50:29 2016 done: Tue Nov 8 00:50:30 2016
Total Scan time: 7.460 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]