Result of FASTA (ccds) for
pFN21AE5441
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5441, 317 aa
1>>>pF1KE5441 317 - 317 aa - 317 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3718+/-0.000636; mu= 15.5719+/- 0.038
mean_var=68.8401+/-13.734, 0's: 0 Z-trim(111.1): 177 B-trim: 18 in 1/51
Lambda= 0.154580
statistics sampled from 11962 (12147) to 11962 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.373), width: 16
Scan time: 2.740
The best scores are: opt bits E(32554)
CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 ( 317) 2241 508.3 3.2e-144
CCDS10476.1 PRSS27 gene_id:83886|Hs108|chr16 ( 290) 995 230.4 1.3e-60
CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 ( 280) 855 199.1 3.3e-51
CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 ( 343) 823 192.1 5.4e-49
CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 ( 321) 772 180.7 1.4e-45
CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 802) 737 173.1 6.5e-43
CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 811) 737 173.1 6.6e-43
CCDS10431.1 TPSAB1 gene_id:7177|Hs108|chr16 ( 275) 723 169.7 2.3e-42
CCDS58452.1 PRSS36 gene_id:146547|Hs108|chr16 ( 752) 725 170.4 3.9e-42
CCDS58453.1 PRSS36 gene_id:146547|Hs108|chr16 ( 850) 725 170.4 4.4e-42
CCDS32436.1 PRSS36 gene_id:146547|Hs108|chr16 ( 855) 725 170.4 4.4e-42
CCDS10478.1 PRSS21 gene_id:10942|Hs108|chr16 ( 314) 712 167.3 1.4e-41
CCDS47145.1 PRSS48 gene_id:345062|Hs108|chr4 ( 328) 667 157.3 1.6e-38
CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059) 670 158.2 2.6e-38
CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 659 155.5 6.5e-38
CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 659 155.5 6.9e-38
CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 659 155.6 7e-38
CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 454) 656 154.9 1.1e-37
CCDS1563.1 PRSS38 gene_id:339501|Hs108|chr1 ( 326) 654 154.4 1.2e-37
CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 ( 638) 650 153.6 3.7e-37
CCDS3847.1 F11 gene_id:2160|Hs108|chr4 ( 625) 647 153.0 5.8e-37
CCDS32993.1 HPN gene_id:3249|Hs108|chr19 ( 417) 621 147.1 2.3e-35
CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 492) 617 146.2 4.9e-35
CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 529) 617 146.2 5.2e-35
CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019) 610 144.8 2.7e-34
CCDS8487.1 ST14 gene_id:6768|Hs108|chr11 ( 855) 603 143.2 6.8e-34
CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 589 140.0 4e-33
CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 589 140.0 4.2e-33
CCDS14101.1 ACR gene_id:49|Hs108|chr22 ( 421) 587 139.5 4.5e-33
CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 586 139.3 6.7e-33
CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 ( 717) 583 138.7 1.3e-32
CCDS219.1 CELA3B gene_id:23436|Hs108|chr1 ( 270) 574 136.5 2.3e-32
CCDS3369.1 HGFAC gene_id:3083|Hs108|chr4 ( 655) 578 137.6 2.6e-32
CCDS75098.1 HGFAC gene_id:3083|Hs108|chr4 ( 662) 578 137.6 2.6e-32
CCDS220.1 CELA3A gene_id:10136|Hs108|chr1 ( 270) 568 135.1 5.8e-32
CCDS3709.1 PRSS12 gene_id:8492|Hs108|chr4 ( 875) 574 136.8 6.1e-32
CCDS157.1 CELA2A gene_id:63036|Hs108|chr1 ( 269) 562 133.8 1.5e-31
CCDS44881.1 TMPRSS12 gene_id:283471|Hs108|chr12 ( 348) 560 133.4 2.5e-31
CCDS10432.1 TPSD1 gene_id:23430|Hs108|chr16 ( 242) 558 132.9 2.5e-31
CCDS75122.1 CORIN gene_id:10699|Hs108|chr4 ( 938) 558 133.2 7.7e-31
CCDS3477.1 CORIN gene_id:10699|Hs108|chr4 (1042) 558 133.2 8.4e-31
CCDS156.1 CTRC gene_id:11330|Hs108|chr1 ( 268) 545 130.0 2e-30
CCDS73602.1 F7 gene_id:2155|Hs108|chr13 ( 382) 544 129.9 3.2e-30
CCDS9529.1 F7 gene_id:2155|Hs108|chr13 ( 444) 544 129.9 3.6e-30
CCDS9528.1 F7 gene_id:2155|Hs108|chr13 ( 466) 544 129.9 3.8e-30
CCDS73251.1 OVCH2 gene_id:341277|Hs108|chr11 ( 565) 544 130.0 4.4e-30
CCDS2745.1 PRSS50 gene_id:29122|Hs108|chr3 ( 385) 538 128.5 8.1e-30
CCDS34302.1 F12 gene_id:2161|Hs108|chr5 ( 615) 529 126.6 4.8e-29
CCDS46816.1 PRSS42 gene_id:339906|Hs108|chr3 ( 293) 525 125.6 4.8e-29
CCDS30605.1 CELA2B gene_id:51032|Hs108|chr1 ( 269) 524 125.3 5.2e-29
>>CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 (317 aa)
initn: 2241 init1: 2241 opt: 2241 Z-score: 2702.6 bits: 508.3 E(32554): 3.2e-144
Smith-Waterman score: 2241; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE5 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 WPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 WPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 VGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 DSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 DSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQG
250 260 270 280 290 300
310
pF1KE5 GGALRAPSQGSGAAARS
:::::::::::::::::
CCDS10 GGALRAPSQGSGAAARS
310
>>CCDS10476.1 PRSS27 gene_id:83886|Hs108|chr16 (290 aa)
initn: 978 init1: 374 opt: 995 Z-score: 1201.4 bits: 230.4 E(32554): 1.3e-60
Smith-Waterman score: 995; 49.1% identity (75.4% similar) in 285 aa overlap (21-301:10-288)
10 20 30 40 50 60
pF1KE5 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE
:::: ... : . :::.:..:::.:::.:. ..:
CCDS10 MRRPAAVPLLLLLC----FGSQRAKAATACGRPRMLNRMVGGQDTQEGE
10 20 30 40
70 80 90 100 110 120
pF1KE5 WPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQK
::: ::::.::.: :.:::.. .::.::::::. : .. :..::::: :: .:: ...
CCDS10 WPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFR-NTSETSLYQVLLGARQLVQPGPHAMY
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 VGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGW
. : :: .:.:. .. ::.:::.:: . :.. .::.:::: :. . . .::..::
CCDS10 ARVRQVESNPLYQ-GTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGW
110 120 130 140 150 160
190 200 210 220 230
pF1KE5 GSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGA--GQGP--ITEDMLCAGYLEGERD
:: .. ::.:. :::: :::::. :. :: . . : : : .::::::. ::..:
CCDS10 GSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKD
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 ACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRG
:: :::::::.: : .:: ::.::::::::..::::::: ..::..:...:. .:..
CCDS10 ACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIHRIIPKLQFQP
230 240 250 260 270 280
300 310
pF1KE5 RAQGGGALRAPSQGSGAAARS
::
CCDS10 ARLGGQK
290
>>CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 (280 aa)
initn: 856 init1: 298 opt: 855 Z-score: 1032.9 bits: 199.1 E(32554): 3.3e-51
Smith-Waterman score: 855; 45.9% identity (71.9% similar) in 281 aa overlap (11-286:3-275)
10 20 30 40 50 60
pF1KE5 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE
: .:: . ::::. : . .: . :::.:.. .:.:::.:. :.:
CCDS42 MRGVSCLQV---LLLLVLGAAGTQGRKSA--ACGQPRMSSRIVGGRDGRDGE
10 20 30 40
70 80 90 100 110 120
pF1KE5 WPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQK
::: .:::. :.: :.:::.. .::.:::::: : . : ::: .::. . :. .
CCDS42 WPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRR-ALPAEYRVRLGALRLGSTSPRTLS
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 VGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGW
: : : : :: ..:: .:.::..:.: . .: :: :.::: . . ::.: : ..::
CCDS42 VPVRRVLLPPDYS-EDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGW
110 120 130 140 150 160
190 200 210 220 230
pF1KE5 GSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDM-----LCAGYLEGER
::.. :::::. . :: ..::..::..:. :: :: . : .: . ::::: .:..
CCDS42 GSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGA-DVPQAERIVLPGSLCAGYPQGHK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE5 DACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLR
::: ::::::: : .:.:.:.:..:::.::: :::::: :.... :..
CCDS42 DACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
230 240 250 260 270 280
300 310
pF1KE5 GRAQGGGALRAPSQGSGAAARS
>>CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 (343 aa)
initn: 841 init1: 335 opt: 823 Z-score: 993.0 bits: 192.1 E(32554): 5.4e-49
Smith-Waterman score: 823; 43.9% identity (67.8% similar) in 289 aa overlap (10-295:7-291)
10 20 30 40 50 60
pF1KE5 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE
:: : ::. . :: :. ..:. : :: : :..:: ... ..
CCDS45 MAQKGVLGPGQLGAVAILLYLGLLRSGTGAEGAEAP-CGVAPQ-ARITGGSSAVAGQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 WPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQK
::: ::: .:.: :.:::.. .::..::::: .. .: . : ::: :: . . ..
CCDS45 WPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEA-YEVKLGAHQLDSYSEDAKV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 VGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGW
. . ::: : .::. .::::..: : : ::. . ::::: :. .: . :: ..::
CCDS45 STLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGLHCTVTGW
120 130 140 150 160 170
190 200 210 220 230
pF1KE5 GSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAG-QGP--ITEDMLCAGYLEGERDA
: . .: : :. ::.:.::.:. :.:. :: : . : . :::.::::.:: .::
CCDS45 GHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 CLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGR
: ::::::: : :.: : :.::.:::..:. ::::::: :.. ::... : .: :
CCDS45 CQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWIQSKVTELQPRVV
240 250 260 270 280 290
300 310
pF1KE5 AQGGGALRAPSQGSGAAARS
CCDS45 PQTQESQPDSNLCGSHLAFSSAPAQGLLRPILFLPLGLALGLLSPWLSEH
300 310 320 330 340
>>CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 (321 aa)
initn: 711 init1: 266 opt: 772 Z-score: 932.0 bits: 180.7 E(32554): 1.4e-45
Smith-Waterman score: 772; 42.4% identity (67.0% similar) in 276 aa overlap (15-287:3-267)
10 20 30 40 50
pF1KE5 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLN---RVVGGEDST
::. ::::: .. . : . :.::.:: . :.:::. .
CCDS10 MALGACGLLLLLAVPGV--SLRT-LQPGCGRPQVSDAGGRIVGGHAAP
10 20 30 40
60 70 80 90 100 110
pF1KE5 DSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSR
. ::: .:.. .: :.::::. .::.::::::. .::. ..: :: ..
CCDS10 AGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSD-YQVHLGELEITLSPHF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 SQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWI
: : . : : . :. .:::::.: . .: :.::.:::.:: . :. .::.
CCDS10 ST---VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 SGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDA
.::: ..: ::: : .:...:: ..:.:.: . : : : . . ::::: .: ::
CCDS10 TGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDY-PGPGGSILQPDMLCA---RGPGDA
170 180 190 200 210
240 250 260 270 280 290
pF1KE5 CLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGR
: ::::::.:::.:::. :: .::::::.. :::::: . :. .:...
CCDS10 CQDDSGGPLVCQVNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSES
220 230 240 250 260 270
300 310
pF1KE5 AQGGGALRAPSQGSGAAARS
CCDS10 GYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
280 290 300 310 320
>>CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 (802 aa)
initn: 585 init1: 344 opt: 737 Z-score: 883.9 bits: 173.1 E(32554): 6.5e-43
Smith-Waterman score: 737; 42.7% identity (70.8% similar) in 253 aa overlap (41-289:559-801)
20 30 40 50 60 70
pF1KE5 GGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKN
:: .:.::: :...:::: .:.:
CCDS74 CEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVR
530 540 550 560 570 580
80 90 100 110 120
pF1KE5 GTHHCAGSLLTSRWVITAAHCFK-DNLNKPYLFSVLLG-AWQLGN-PGSRSQKVGVAWVE
: : :.:.:...::::::::::. :.. . :..:.:: .:: . :: : ::. .
CCDS74 GRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLL-
590 600 610 620 630 640
130 140 150 160 170 180
pF1KE5 PHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGV
:: : ... :.::..:.. . : : :.::: : . :. ::::.:::....:
CCDS74 -HP-YHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG
650 660 670 680 690 700
190 200 210 220 230 240
pF1KE5 PLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLM
:. . .:::. : .: ...::..: . .: :::::: .:..::: :::::::.
CCDS74 PISN--ALQKVDVQLIPQDLCSEVY-----RYQVTPRMLCAGYRKGKKDACQGDSGGPLV
710 720 730 740 750
250 260 270 280 290 300
pF1KE5 CQ-VDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRA
:. ..: :.:::..::: ::.. : ::: ... ::....:
CCDS74 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
760 770 780 790 800
310
pF1KE5 PSQGSGAAARS
>>CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 (811 aa)
initn: 585 init1: 344 opt: 737 Z-score: 883.8 bits: 173.1 E(32554): 6.6e-43
Smith-Waterman score: 737; 42.7% identity (70.8% similar) in 253 aa overlap (41-289:568-810)
20 30 40 50 60 70
pF1KE5 GGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKN
:: .:.::: :...:::: .:.:
CCDS13 CEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVR
540 550 560 570 580 590
80 90 100 110 120
pF1KE5 GTHHCAGSLLTSRWVITAAHCFK-DNLNKPYLFSVLLG-AWQLGN-PGSRSQKVGVAWVE
: : :.:.:...::::::::::. :.. . :..:.:: .:: . :: : ::. .
CCDS13 GRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLL-
600 610 620 630 640 650
130 140 150 160 170 180
pF1KE5 PHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGV
:: : ... :.::..:.. . : : :.::: : . :. ::::.:::....:
CCDS13 -HP-YHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG
660 670 680 690 700 710
190 200 210 220 230 240
pF1KE5 PLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLM
:. . .:::. : .: ...::..: . .: :::::: .:..::: :::::::.
CCDS13 PISN--ALQKVDVQLIPQDLCSEVY-----RYQVTPRMLCAGYRKGKKDACQGDSGGPLV
720 730 740 750 760
250 260 270 280 290 300
pF1KE5 CQ-VDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRA
:. ..: :.:::..::: ::.. : ::: ... ::....:
CCDS13 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
770 780 790 800 810
310
pF1KE5 PSQGSGAAARS
>>CCDS10431.1 TPSAB1 gene_id:7177|Hs108|chr16 (275 aa)
initn: 599 init1: 273 opt: 723 Z-score: 874.0 bits: 169.7 E(32554): 2.3e-42
Smith-Waterman score: 723; 40.3% identity (66.9% similar) in 278 aa overlap (20-289:3-271)
10 20 30 40 50 60
pF1KE5 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE
.::::: .. :.: . :: :. : .:::... :.
CCDS10 MLNLLLLALPVL--ASRAYAAPAPGQALQRVGIVGGQEAPRSK
10 20 30 40
70 80 90 100 110
pF1KE5 WPWIVSIQKNGT---HHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSR
::: ::.. .: : :.:::. .::.::::: ... . : : .: .
CCDS10 WPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLY---YQ
50 60 70 80 90
120 130 140 150 160 170
pF1KE5 SQKVGVAWVEPHP-VYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCW
.: . :. . :: :. . : :::::..::. .. : .: . :: :: .::. ::
CCDS10 DQLLPVSRIIVHPQFYTAQIG--ADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCW
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE5 ISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGP----ITEDMLCAGYLE
..:::.... :: : :...::::.....:. : :: : . .:::::: .
CCDS10 VTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--N
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE5 GERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGV
.::.: :::::::.:.:.:.:: ::..:::::::. ::::.: .. . .:... :
CCDS10 TRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKK
220 230 240 250 260 270
300 310
pF1KE5 QLRGRAQGGGALRAPSQGSGAAARS
CCDS10 P
>>CCDS58452.1 PRSS36 gene_id:146547|Hs108|chr16 (752 aa)
initn: 711 init1: 298 opt: 725 Z-score: 869.9 bits: 170.4 E(32554): 3.9e-42
Smith-Waterman score: 725; 41.3% identity (68.3% similar) in 259 aa overlap (41-291:38-292)
20 30 40 50 60 70
pF1KE5 GGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKN
::.:. :.::: .. . ::: ::....
CCDS58 PLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHG
10 20 30 40 50 60
80 90 100 110 120
pF1KE5 GTHHCAGSLLTSRWVITAAHCFKDN--LNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEP
: : :.:::.. ::..::::: : :. .:::::. . .: . .. .:: .
CCDS58 GGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 HPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVP
:: : . ::.::.:: ... : :.::: :: .. .: :: .:::..:.. :
CCDS58 PANYSQVELG-ADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGP------ITEDMLCAGYLEGERDACLGDS
:: : .::.... .. .:. :: . :: : :::::: ::.::.: :::
CCDS58 LPLPWVLQEVELRLLGEATCQCLY---SQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 GGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGG
::::.:. : :. ::: :.: ::..::::::. .......:... :.:
CCDS58 GGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQP
250 260 270 280 290 300
310
pF1KE5 ALRAPSQGSGAAARS
CCDS58 QKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPAS
310 320 330 340 350 360
>--
initn: 343 init1: 120 opt: 419 Z-score: 501.0 bits: 102.2 E(32554): 1.4e-21
Smith-Waterman score: 419; 30.9% identity (57.7% similar) in 246 aa overlap (53-294:326-559)
30 40 50 60 70 80
pF1KE5 LLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTS
:. . ::: .... :.. : :.:..
CCDS58 GPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSE
300 310 320 330 340 350
90 100 110 120 130 140
pF1KE5 RWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADI
::.. : :: : :. : ::.. : :: . :: . : :: ... :.
CCDS58 SWVLAPASCFLDP-NSSDSPPRDLDAWRVLLP-SRPRAERVARLVQHENASWDNAS--DL
360 370 380 390 400 410
150 160 170 180 190 200
pF1KE5 ALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPI
::..:. ...: :.::: .. :...: .. :: : : : .: :.. .
CCDS58 ALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGR---GEPALGPGAL--LEAEL
420 430 440 450 460
210 220 230 240 250
pF1KE5 IDSEVCSHLYWRGAGQGPITED---MLCAGYLEGER-DACLGDSGGPLMCQVDGAWLLAG
. . : :: : .. :. : :: .: : :. .: .:: :.:: .:.:.:::
CCDS58 LGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAG
470 480 490 500 510 520
260 270 280 290 300 310
pF1KE5 IISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS
: .. :: :: ... :..: :. ....:. :
CCDS58 IRDFPSGCL---RPRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHT
530 540 550 560 570 580
CCDS58 EHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYI
590 600 610 620 630 640
>>CCDS58453.1 PRSS36 gene_id:146547|Hs108|chr16 (850 aa)
initn: 711 init1: 298 opt: 725 Z-score: 869.1 bits: 170.4 E(32554): 4.4e-42
Smith-Waterman score: 725; 41.3% identity (68.3% similar) in 259 aa overlap (41-291:38-292)
20 30 40 50 60 70
pF1KE5 GGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKN
::.:. :.::: .. . ::: ::....
CCDS58 PLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQVSLHHG
10 20 30 40 50 60
80 90 100 110 120
pF1KE5 GTHHCAGSLLTSRWVITAAHCFKDN--LNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEP
: : :.:::.. ::..::::: : :. .:::::. . .: . .. .:: .
CCDS58 GGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 HPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVP
:: : . ::.::.:: ... : :.::: :: .. .: :: .:::..:.. :
CCDS58 PANYSQVELG-ADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGP------ITEDMLCAGYLEGERDACLGDS
:: : .::.... .. .:. :: . :: : :::::: ::.::.: :::
CCDS58 LPLPWVLQEVELRLLGEATCQCLY---SQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 GGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGG
::::.:. : :. ::: :.: ::..::::::. .......:... :.:
CCDS58 GGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVATYEAWIREQVMGSEPGPAFPTQP
250 260 270 280 290 300
310
pF1KE5 ALRAPSQGSGAAARS
CCDS58 QKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPAS
310 320 330 340 350 360
>--
initn: 374 init1: 120 opt: 404 Z-score: 482.2 bits: 98.8 E(32554): 1.5e-20
Smith-Waterman score: 404; 30.6% identity (57.1% similar) in 245 aa overlap (53-294:326-554)
30 40 50 60 70 80
pF1KE5 LLASTAILNAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTS
:. . ::: .... :.. : :.:..
CCDS58 GPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQVMVPGSRPCHGALVSE
300 310 320 330 340 350
90 100 110 120 130 140
pF1KE5 RWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADI
::.. : :: : :. : ::.. : :: . :: . : :: ... :.
CCDS58 SWVLAPASCFLDP-NSSDSPPRDLDAWRVLLP-SRPRAERVARLVQHENASWDNAS--DL
360 370 380 390 400 410
150 160 170 180 190 200
pF1KE5 ALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPI
::..:. ...: :.::: .. :...: .. :: : : : .: :.. .
CCDS58 ALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARWGR---GEPALGPGAL--LEAEL
420 430 440 450 460
210 220 230 240 250
pF1KE5 IDSEVCSHLYWRGAGQGPITED---MLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGI
. . : :: : .. :. : :: .: : :.. :: :.:: .:.:.::::
CCDS58 LGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEN----DSRWSLLCQEEGTWFLAGI
470 480 490 500 510 520
260 270 280 290 300 310
pF1KE5 ISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS
.. :: :: ... :..: :. ....:. :
CCDS58 RDFPSGCL---RPRAFFPLQTHGPWISHVTRGAYLEDQLAWDWGPDGEETETQTCPPHTE
530 540 550 560 570
CCDS58 HGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIE
580 590 600 610 620 630
>--
initn: 339 init1: 119 opt: 357 Z-score: 425.5 bits: 88.4 E(32554): 2.2e-17
Smith-Waterman score: 361; 29.9% identity (56.4% similar) in 234 aa overlap (61-289:596-802)
40 50 60 70 80 90
pF1KE5 NAARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAH
:::.. .. : . :.: ::. ::..:.:
CCDS58 GEETETQTCPPHTEHGACGLRLEAAPVGVLWPWLAEVHVAGDRVCTGILLAPGWVLAATH
570 580 590 600 610 620
100 110 120 130 140
pF1KE5 CF--KDNLNKPYLFSVLLG-AWQLGNP-GSRSQKVGVAWVEPHPVYSWKEGACADIALVR
: . . ::. : :: : . : : . ... .. :. . : .::..
CCDS58 CVLRPGSTTVPYI-EVYLGRAGASSLPQGHQVSRLVISIRLPQHL-----GLRPPLALLE
630 640 650 660 670
150 160 170 180 190 200
pF1KE5 LERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSE
: .. : .::::: :.: ::.. ::. :: :: ::. : :. ..
CCDS58 LSSRVEPSPSALPICLHPAGI--PPGASCWVLGWKEPQDRVPVAAA-------VSILTQR
680 690 700 710 720 730
210 220 230 240 250 260
pF1KE5 VCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQV-DGAWLLAGIISWGEG
.:. :: :: . ::. : ::... : :. ::.::. .:.:.:.:. :
CCDS58 ICDCLY-----QGILPPGTLCVLYAEGQENRCEMTSAPPLLCQMTEGSWILVGMAVQG--
740 750 760 770 780
270 280 290 300 310
pF1KE5 CAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARS
.: .. ... ...:. . :
CCDS58 ----SRE-LFAAIGPEEAWISQTVGEANFLPPSGSPHWPTGGSNLCPPELAKASGSPHAV
790 800 810 820 830
317 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:47:39 2016 done: Tue Nov 8 00:47:40 2016
Total Scan time: 2.740 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]