FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE5429, 335 aa
  1>>>pF1KE5429 335 - 335 aa - 335 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4864+/-0.000851; mu= 14.9192+/- 0.051
 mean_var=64.0261+/-12.848, 0's: 0 Z-trim(106.1): 23  B-trim: 0 in 0/50
 Lambda= 0.160286
 statistics sampled from 8767 (8777) to 8767 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.27), width:  16
 Scan time:  2.290

The best scores are:                                      opt bits E(32554)
CCDS2246.1 METAP1D gene_id:254042|Hs108|chr2       ( 335) 2289 538.0 4.1e-153
CCDS47110.1 METAP1 gene_id:23173|Hs108|chr4        ( 386)  844 203.9 1.8e-52


>>CCDS2246.1 METAP1D gene_id:254042|Hs108|chr2            (335 aa)
 initn: 2289 init1: 2289 opt: 2289  Z-score: 2862.4  bits: 538.0 E(32554): 4.1e-153
Smith-Waterman score: 2289; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335)

               10        20        30        40        50        60
pF1KE5 MAAPSGVHLLVRRGSHRIFSSPLNHIYLHKQSSSQQRRNFFFRRQRDISHSIVLPAAVSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 MAAPSGVHLLVRRGSHRIFSSPLNHIYLHKQSSSQQRRNFFFRRQRDISHSIVLPAAVSS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE5 AHPVPKHIKKPDYVTTGIVPDWGDSIEVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 AHPVPKHIKKPDYVTTGIVPDWGDSIEVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE5 TEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 TEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE5 VYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDEAIAACRAGAPFSVIGNTISHITHQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 VYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDEAIAACRAGAPFSVIGNTISHITHQ
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE5 NGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDLPMEEGMAFTIEPIITEGSPEFKVLEDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 NGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDLPMEEGMAFTIEPIITEGSPEFKVLEDA
              250       260       270       280       290       300

              310       320       330     
pF1KE5 WTVVSLDNQRSAQFEHTVLITSRGAQILTKLPHEA
       :::::::::::::::::::::::::::::::::::
CCDS22 WTVVSLDNQRSAQFEHTVLITSRGAQILTKLPHEA
              310       320       330     

>>CCDS47110.1 METAP1 gene_id:23173|Hs108|chr4             (386 aa)
 initn: 811 init1: 595 opt: 844  Z-score: 1055.5  bits: 203.9 E(32554): 1.8e-52
Smith-Waterman score: 844; 47.1% identity (75.7% similar) in 276 aa overlap (63-330:98-373)

             40        50        60        70          80          
pF1KE5 SSQQRRNFFFRRQRDISHSIVLPAAVSSAHPVPKHIKKPDYVT--TGIVPDW----GDS-
                                     :::..:..:::.    :.  .     : : 
CCDS47 TVEGDINTDPWAGYRYTGKLRPHYPLMPTRPVPSYIQRPDYADHPLGMSESEQALKGTSQ
        70        80        90       100       110       120       

          90       100       110       120       130       140     
pF1KE5 IEVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMTTEEIDALVHREIISHNAYPSPLGYG
       :.. . ..:.:.. .:.:::.:: .:.  .:  .::::::  ::   :..: :::::.: 
CCDS47 IKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACIARNCYPSPLNYY
       130       140       150       160       170       180       

         150       160       170       180       190       200     
pF1KE5 GFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDECGKK
       .:::: :::::.:.:::::: ::::.:::.:.:.:.: :::::: .:::.::.::. ..:
CCDS47 NFPKSCCTSVNEVICHGIPDRRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDDGARK
       190       200       210       220       230       240       

         210       220       230       240       250       260     
pF1KE5 LVEVARRCRDEAIAACRAGAPFSVIGNTISHITHQNGFQVCPHFVGHGIGSYFHGHPEIW
       ::... .:  .:: : . :. .  .:: :.. .. :::.:   . :::: . ::  :.. 
CCDS47 LVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTAPNVP
       250       260       270       280       290       300       

         270        280       290       300       310       320    
pF1KE5 HHANDSDLP-MEEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEHTVLITSRG
       :.:... .  :. : .:::::.: ::. . ..  :.::.:. :..::::::::.:.:. :
CCDS47 HYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLVTDTG
       310       320       330       340       350       360       

          330             
pF1KE5 AQILTKLPHEA        
        .:::.             
CCDS47 CEILTRRLDSARPHFMSQF
       370       380      




335 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 00:41:03 2016 done: Tue Nov  8 00:41:03 2016
 Total Scan time:  2.290 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]