Result of FASTA (omim) for
pFN21AE5366
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5366, 190 aa
1>>>pF1KE5366 190 - 190 aa - 190 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0211+/-0.000365; mu= 14.4440+/- 0.023
mean_var=64.3858+/-12.191, 0's: 0 Z-trim(113.6): 20 B-trim: 0 in 0/51
Lambda= 0.159838
statistics sampled from 22929 (22946) to 22929 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.269), width: 16
Scan time: 4.430
The best scores are: opt bits E(85289)
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 1253 297.4 9.2e-81
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 1251 296.9 1.3e-80
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1064 253.8 1.2e-67
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1037 247.6 9e-66
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1033 246.7 1.7e-65
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1001 239.3 2.8e-63
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 995 237.9 7.4e-63
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 994 237.7 8.7e-63
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 985 235.6 3.7e-62
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 985 235.6 3.7e-62
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 958 229.4 2.7e-60
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 939 225.0 5.7e-59
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 917 219.9 1.9e-57
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 667 162.3 4.5e-40
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 383 96.8 2.4e-20
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 310 79.9 2.6e-15
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 162 45.8 5.3e-05
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 1253 init1: 1253 opt: 1253 Z-score: 1571.0 bits: 297.4 E(85289): 9.2e-81
Smith-Waterman score: 1253; 99.5% identity (100.0% similar) in 190 aa overlap (1-190:1-190)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MMASPFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
130 140 150 160 170 180
190
pF1KE5 NLQERLRRKE
::::::::::
NP_008 NLQERLRRKE
190
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 1251 init1: 1251 opt: 1251 Z-score: 1568.5 bits: 296.9 E(85289): 1.3e-80
Smith-Waterman score: 1251; 100.0% identity (100.0% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
::::::::::
NP_076 NLQERLRRKE
180
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1064 init1: 1064 opt: 1064 Z-score: 1335.4 bits: 253.8 E(85289): 1.2e-67
Smith-Waterman score: 1064; 84.1% identity (94.2% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: ::.:::.::::.::: ::::::::.::::.::::::..:::.:::: ::: :::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
::::::::::::::: :::::::.::: ::::.::::::.::: ::::: ::::::::::
NP_002 GFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
:::.::: : .:::::.::::.:.:::.::::::::::::::::::::::::::.:::.
NP_002 EACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSA
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
::::::::::
NP_002 NLQERLRRKE
180
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1037 init1: 1037 opt: 1037 Z-score: 1301.8 bits: 247.6 E(85289): 9e-66
Smith-Waterman score: 1037; 84.7% identity (90.5% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: ::::::.:::::::::::: ::::.:::: .:::.:::::: ::: ::: :::::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
:::::::::::::: :::::::.::: ::::.:::::.:::: ::::. ::::::::::
NP_066 RFPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::::: :: ::::: ::::::.:::.::::::::::::::::::::::::::.: :
NP_066 EACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSR
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
::::::::::
NP_066 NLQERLRRKE
180
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1092 init1: 1033 opt: 1033 Z-score: 1296.8 bits: 246.7 E(85289): 1.7e-65
Smith-Waterman score: 1033; 82.0% identity (91.5% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: ::::.:.::::::::::::::.: .::::.:::::::.::: :::: ::: :::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
:::::::::::::: :::::::..:: ::::.::.::::::: ::.:: ::.::.:::
NP_002 EFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::.:: : :::::: ::::::::::.:::::: :::::::::::::::::::::.::
NP_002 EACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFST
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
:::.:::::.
NP_002 NLQKRLRRKD
180
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1001 init1: 1001 opt: 1001 Z-score: 1256.9 bits: 239.3 E(85289): 2.8e-63
Smith-Waterman score: 1001; 81.0% identity (91.5% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: :.:::...::: :: ::::::::.:::: :::.:.:::::.:::: ::: :::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
::::::::::::::: :::::::.::: ::::.::::::.:...::.:: ::: ::::::
NP_002 GFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::.:: : ::::::.::::::::::.::::::::::::::::::::::::::.:::
NP_002 EACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSK
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
.::::::::
NP_002 IFQERLRRKE
180
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1010 init1: 995 opt: 995 Z-score: 1249.5 bits: 237.9 E(85289): 7.4e-63
Smith-Waterman score: 995; 79.9% identity (92.1% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: :.:::...::: :: ::::::::.:::: :::.:.:::::.::: ::: :::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
:::.:::::.::::: :::::::.::: ::::.:.::::::...::.:: ::::::::::
NP_066 GFPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::.:: : :::::: ::::::.:::.::::::::::::::::::::::::::::.::
NP_066 EACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFST
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
:::.:::::.
NP_066 NLQKRLRRKD
180
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 992 init1: 650 opt: 994 Z-score: 1248.2 bits: 237.7 E(85289): 8.7e-63
Smith-Waterman score: 994; 82.0% identity (89.4% similar) in 189 aa overlap (2-190:1-188)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: ::::..:.:::::::::.:::::.:::: .:::::::::: ::: ::: :::::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
::::::: ::::::: .: ::::.::::::::.:::::::::: ::::: ::::::::::
NP_000 GFPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::.: : :::::. ::::::.:::.:::::: :::::::::::::::::::.::::
NP_000 EACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLST
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
:::: :: ::
NP_000 NLQESLRSKE
180
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1005 init1: 985 opt: 985 Z-score: 1237.0 bits: 235.6 E(85289): 3.7e-62
Smith-Waterman score: 985; 78.8% identity (92.1% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: :.:::...::: :: ::::::::.:::: :::.:.:::::.:::: ::: :::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
:.::::::::::::. :::::::.::: ::::.:.::::::...::.:: ::::::::.:
NP_067 GLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::.:: . :::::: ::::::.:::.::::::::::::::::::::::::::::.::
NP_067 EACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFST
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
:::. ::::.
NP_067 NLQKILRRKD
180
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1000 init1: 985 opt: 985 Z-score: 1237.0 bits: 235.6 E(85289): 3.7e-62
Smith-Waterman score: 985; 78.8% identity (91.5% similar) in 189 aa overlap (2-190:1-189)
10 20 30 40 50 60
pF1KE5 MMASPFALLMVLVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDF
:: :.:::...::: :: ::::::::.:::: :::.:.::.::.:::: ::: :::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
.::::::::::::: :::::::.::: ::::.:.::::::...::.:: ::::::::::
NP_002 RIPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 EACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLST
::::.:: : :::::: ::::::.:::.:::::: :.:::::::::::::::::::.::
NP_002 EACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFST
120 130 140 150 160 170
190
pF1KE5 NLQERLRRKE
:::.:::::.
NP_002 NLQKRLRRKD
180
190 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:09:10 2016 done: Tue Nov 8 00:09:10 2016
Total Scan time: 4.430 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]