Result of FASTA (ccds) for
pFN21AE5332
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5332, 290 aa
1>>>pF1KE5332 290 - 290 aa - 290 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7114+/-0.00117; mu= 13.2810+/- 0.070
mean_var=95.7358+/-19.414, 0's: 0 Z-trim(104.1): 103 B-trim: 343 in 1/49
Lambda= 0.131080
statistics sampled from 7640 (7749) to 7640 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.238), width: 16
Scan time: 2.320
The best scores are: opt bits E(32554)
CCDS6464.1 CD274 gene_id:29126|Hs108|chr9 ( 290) 1903 370.5 8e-103
CCDS59118.1 CD274 gene_id:29126|Hs108|chr9 ( 176) 1049 208.8 2.3e-54
CCDS10251.1 CD276 gene_id:80381|Hs108|chr15 ( 316) 416 89.3 3.8e-18
CCDS32288.1 CD276 gene_id:80381|Hs108|chr15 ( 534) 412 88.8 9.6e-18
CCDS6465.1 PDCD1LG2 gene_id:80380|Hs108|chr9 ( 273) 366 79.8 2.4e-15
>>CCDS6464.1 CD274 gene_id:29126|Hs108|chr9 (290 aa)
initn: 1903 init1: 1903 opt: 1903 Z-score: 1959.4 bits: 370.5 E(32554): 8e-103
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 290 aa overlap (1-290:1-290)
10 20 30 40 50 60
pF1KE5 MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 DKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 ADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 TTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 TTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTH
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 LVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEET
250 260 270 280 290
>>CCDS59118.1 CD274 gene_id:29126|Hs108|chr9 (176 aa)
initn: 1049 init1: 1049 opt: 1049 Z-score: 1089.5 bits: 208.8 E(32554): 2.3e-54
Smith-Waterman score: 1049; 99.4% identity (100.0% similar) in 161 aa overlap (130-290:16-176)
100 110 120 130 140 150
pF1KE5 QITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEG
.:::::::::::::::::::::::::::::
CCDS59 MRIFAVFIFMTYWHLLNAPYNKINQRILVVDPVTSEHELTCQAEG
10 20 30 40
160 170 180 190 200 210
pF1KE5 YPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 YPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEEN
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE5 HTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 HTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNS
110 120 130 140 150 160
280 290
pF1KE5 KKQSDTHLEET
:::::::::::
CCDS59 KKQSDTHLEET
170
>>CCDS10251.1 CD276 gene_id:80381|Hs108|chr15 (316 aa)
initn: 311 init1: 180 opt: 416 Z-score: 439.2 bits: 89.3 E(32554): 3.8e-18
Smith-Waterman score: 416; 30.2% identity (59.3% similar) in 285 aa overlap (13-288:22-300)
10 20 30 40 50
pF1KE5 MRIFAVFIFMTYWH-LLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDL
: : .:. : ::.: :. :.. :. :.: : ..:
CCDS10 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 AALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAG
: : . :.. : . :.::. . . : :.: .:. :. : :. :::.:.. :.. : :
CCDS10 AQLNLIWQLTDTK--QLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEG
70 80 90 100 110
120 130 140 150 160
pF1KE5 VYRCMISYGGADYKRITVKVNAPYNKI------NQRILVVDPVTSEHELTCQA-EGYPKA
. :..: ....: :::.: :. . : :: .::.. .:::.:
CCDS10 SFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVT----ITCSSYRGYPEA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE5 EVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAE
::.: ... :.:..::.. :. ::.: :.::. .: . : : ... .
CCDS10 EVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 LVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQ-
..: :.. ::. : :.. :. : :::.:. . . . .. : .: ... .
CCDS10 VTITGQPMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDGEGEG
240 250 260 270 280 290
290
pF1KE5 SDTHLEET
: : :.
CCDS10 SKTALQPLKHSDSKEDDGQEIA
300 310
>>CCDS32288.1 CD276 gene_id:80381|Hs108|chr15 (534 aa)
initn: 443 init1: 180 opt: 412 Z-score: 432.0 bits: 88.8 E(32554): 9.6e-18
Smith-Waterman score: 412; 30.1% identity (59.5% similar) in 279 aa overlap (18-288:246-518)
10 20 30 40
pF1KE5 MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQ
: : ::.: :. :.. :..:.: :
CCDS32 GTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPG
220 230 240 250 260 270
50 60 70 80 90 100
pF1KE5 LDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQ
..:: : . :.. : . :.::. . . : :.: .:. :. : :. :::.:.. :..
CCDS32 FSLAQLNLIWQLTDTK--QLVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVA
280 290 300 310 320 330
110 120 130 140 150 160
pF1KE5 DAGVYRCMISYGGADYKRITVKVNAPYNKI------NQRILVVDPVTSEHELTCQA-EGY
: : . :..: ....: :::.: :. . : :: .::.. .::
CCDS32 DEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVT----ITCSSYRGY
340 350 360 370 380
170 180 190 200 210 220
pF1KE5 PKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENH
:.:::.: ... :.:..::.. :. ::.: :.::. .: . : : ...
CCDS32 PEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDA
390 400 410 420 430 440
230 240 250 260 270 280
pF1KE5 TAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSK
. ..: :.. ::. : :.. :. : :::.:. . . . .. : .: ...
CCDS32 HGSVTITGQPMTFPPEALWVTVGLSVCLIALLVALAFVCWRKIKQSCEEENAGAEDQDGE
450 460 470 480 490 500
290
pF1KE5 KQ-SDTHLEET
. : : :.
CCDS32 GEGSKTALQPLKHSDSKEDDGQEIA
510 520 530
>--
initn: 247 init1: 145 opt: 374 Z-score: 393.2 bits: 81.6 E(32554): 1.4e-15
Smith-Waterman score: 374; 31.6% identity (60.0% similar) in 225 aa overlap (13-228:22-240)
10 20 30 40 50
pF1KE5 MRIFAVFIFMTYWH-LLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDL
: : .:. : ::.: :. :.. :. :.: : ..:
CCDS32 MLRRRGSPGMGVHVGAALGALWFCLTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 AALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAG
: : . :.. : . :.::. . . : :.: .:. :. : :. :::.:.. :.. : :
CCDS32 AQLNLIWQLTDTK--QLVHSFAEGQDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEG
70 80 90 100 110
120 130 140 150 160
pF1KE5 VYRCMISYGGADYKRITVKVNAPYNKI------NQRILVVDPVTSEHELTCQA-EGYPKA
. :..: ....: :::.: :. . : :: .::.. .:::.:
CCDS32 SFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVT----ITCSSYQGYPEA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE5 EVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRR-LDPEENHTA
::.: ... :.:..::.. :. ::.: : ::. .: . : : . .. :..
CCDS32 EVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSS
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE5 ELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQ
. :.
CCDS32 VTITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLV
240 250 260 270 280 290
>>CCDS6465.1 PDCD1LG2 gene_id:80380|Hs108|chr9 (273 aa)
initn: 362 init1: 208 opt: 366 Z-score: 388.9 bits: 79.8 E(32554): 2.4e-15
Smith-Waterman score: 494; 38.6% identity (65.4% similar) in 280 aa overlap (14-288:15-268)
10 20 30 40 50
pF1KE5 MRIFAVFIFMTYWHLLNA-FTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWE
: . : :::::::.::..:.:::.:.::.: . ....:.:. .
CCDS64 MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITAS--
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 MEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISY
.: : :.: : .:.:: ::..:: ::.:...: .:...: : :.:.: :
CCDS64 ------LQKV--ENDT----SPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIY
60 70 80 90 100
120 130 140 150 160 170
pF1KE5 GGA-DYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSG
: : ::: .:.::.: : ::: .:: : : :.: :::::: ::: ::: : . .:
CCDS64 GVAWDYKYLTLKVKASYRKINTHILKV-PETDEVELTCQATGYPLAEVSWPN-----VSV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE5 KTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNE
..:..:. : :..:::.::.. .. : :.: ..:. ::.. . : .
CCDS64 PANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFW-----NTHVRELTLASIDLQSQMEP
170 180 190 200 210
240 250 260 270 280 290
pF1KE5 RTHLVILGAILL--CLGVALTFIFRLRKGRMMDVKKC-GIQDTNSKKQSDTHLEET
::: . : :.. :. .:. :: . : . .: . .::... . :. :
CCDS64 RTHPTWLLHIFIPFCI-IAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI
220 230 240 250 260 270
290 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:51:28 2016 done: Mon Nov 7 23:51:28 2016
Total Scan time: 2.320 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]