Result of FASTA (omim) for
pFN21AE5301
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5301, 260 aa
1>>>pF1KE5301 260 - 260 aa - 260 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.2894+/-0.000269; mu= 21.3514+/- 0.017
mean_var=64.3201+/-13.146, 0's: 0 Z-trim(120.2): 10 B-trim: 1947 in 1/56
Lambda= 0.159919
statistics sampled from 35211 (35221) to 35211 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.413), width: 16
Scan time: 5.790
The best scores are: opt bits E(85289)
NP_665813 (OMIM: 606898) voltage-dependent calcium ( 260) 1760 413.8 1.6e-115
XP_006723379 (OMIM: 606898) PREDICTED: voltage-dep ( 189) 1207 286.1 3.3e-77
NP_665814 (OMIM: 606898) voltage-dependent calcium ( 214) 919 219.7 3.6e-57
NP_114103 (OMIM: 606898) voltage-dependent calcium ( 189) 752 181.1 1.3e-45
NP_000718 (OMIM: 114209) voltage-dependent calcium ( 222) 559 136.6 3.7e-32
>>NP_665813 (OMIM: 606898) voltage-dependent calcium cha (260 aa)
initn: 1760 init1: 1760 opt: 1760 Z-score: 2195.1 bits: 413.8 E(85289): 1.6e-115
Smith-Waterman score: 1760; 100.0% identity (100.0% similar) in 260 aa overlap (1-260:1-260)
10 20 30 40 50 60
pF1KE5 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 TTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 SGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLL
190 200 210 220 230 240
250 260
pF1KE5 LTLPSWPWGSLCPKRGHRAT
::::::::::::::::::::
NP_665 LTLPSWPWGSLCPKRGHRAT
250 260
>>XP_006723379 (OMIM: 606898) PREDICTED: voltage-depende (189 aa)
initn: 1204 init1: 1204 opt: 1207 Z-score: 1507.2 bits: 286.1 E(85289): 3.3e-77
Smith-Waterman score: 1207; 97.8% identity (98.9% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KE5 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 SGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLL
:. .:
XP_006 SASQMLPAI
>>NP_665814 (OMIM: 606898) voltage-dependent calcium cha (214 aa)
initn: 1460 init1: 918 opt: 919 Z-score: 1147.5 bits: 219.7 E(85289): 3.6e-57
Smith-Waterman score: 1372; 82.3% identity (82.3% similar) in 260 aa overlap (1-260:1-214)
10 20 30 40 50 60
pF1KE5 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGL
:::::::::::::::
NP_665 TTGENARIFQRTTKK---------------------------------------------
130
190 200 210 220 230 240
pF1KE5 SGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 -GLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLL
140 150 160 170 180 190
250 260
pF1KE5 LTLPSWPWGSLCPKRGHRAT
::::::::::::::::::::
NP_665 LTLPSWPWGSLCPKRGHRAT
200 210
>>NP_114103 (OMIM: 606898) voltage-dependent calcium cha (189 aa)
initn: 1294 init1: 752 opt: 752 Z-score: 939.9 bits: 181.1 E(85289): 1.3e-45
Smith-Waterman score: 1156; 72.7% identity (72.7% similar) in 260 aa overlap (1-260:1-189)
10 20 30 40 50 60
pF1KE5 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFF
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 FWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPG----------
70 80 90 100 110
130 140 150 160 170 180
pF1KE5 TTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGL
NP_114 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE5 SGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 -GLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLL
120 130 140 150 160
250 260
pF1KE5 LTLPSWPWGSLCPKRGHRAT
::::::::::::::::::::
NP_114 LTLPSWPWGSLCPKRGHRAT
170 180
>>NP_000718 (OMIM: 114209) voltage-dependent calcium cha (222 aa)
initn: 584 init1: 328 opt: 559 Z-score: 698.4 bits: 136.6 E(85289): 3.7e-32
Smith-Waterman score: 559; 39.7% identity (72.6% similar) in 219 aa overlap (38-252:8-215)
10 20 30 40 50 60
pF1KE5 LQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTEFWVELNT
::...:. .: .::. .: :. :. :.
NP_000 MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSP
10 20 30
70 80 90 100 110 120
pF1KE5 YKANGSAVCEAAHLGLWKACTKRLWQADVPVDRD-TCGPAELPGEANCTYFKFFTTGENA
. . ...:::::.:::. :::: .:.: . :::: :::: ::.::. :. ::..
NP_000 HMEHHNTTCEAAHFGLWRICTKR-----IPMDDSKTCGPITLPGEKNCSYFRHFNPGESS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 RIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLLL
.::. ::.:: ...::.::...:. . :: ::... :.: ..::: ... ....:: .:
NP_000 EIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCIL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 VSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSW
::.::.:.::. .. . . . : ::::..:. .: ..:.::. .::..::
NP_000 VSVEVMRQSVKRMI-----DSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRM
160 170 180 190 200
250 260
pF1KE5 P---WGSLCPKRGHRAT
: : : :
NP_000 PRNPWES-CMDAEPEH
210 220
260 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 07:28:33 2016 done: Tue Nov 8 07:28:34 2016
Total Scan time: 5.790 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]