Result of FASTA (omim) for
pFN21AE5278
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5278, 235 aa
1>>>pF1KE5278 235 - 235 aa - 235 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8006+/-0.000298; mu= 12.4521+/- 0.019
mean_var=90.0541+/-18.044, 0's: 0 Z-trim(119.4): 141 B-trim: 439 in 1/58
Lambda= 0.135152
statistics sampled from 33132 (33299) to 33132 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.39), width: 16
Scan time: 6.830
The best scores are: opt bits E(85289)
NP_542178 (OMIM: 616776) dual specificity protein ( 235) 1604 322.1 5.2e-88
NP_001307407 (OMIM: 616776) dual specificity prote ( 232) 1557 312.9 2.9e-85
XP_016883146 (OMIM: 616776) PREDICTED: dual specif ( 298) 1000 204.4 1.8e-52
XP_016883145 (OMIM: 616776) PREDICTED: dual specif ( 311) 999 204.2 2.1e-52
XP_016883143 (OMIM: 616776) PREDICTED: dual specif ( 335) 999 204.2 2.2e-52
NP_001307408 (OMIM: 616776) dual specificity prote ( 295) 953 195.2 1e-49
XP_016883144 (OMIM: 616776) PREDICTED: dual specif ( 332) 952 195.1 1.3e-49
NP_001012662 (OMIM: 616776) dual specificity prote ( 132) 895 183.7 1.4e-46
NP_817130 (OMIM: 616776) dual specificity protein ( 132) 895 183.7 1.4e-46
NP_001273484 (OMIM: 616778) dual specificity prote ( 205) 687 143.3 3.1e-34
NP_064570 (OMIM: 616778) dual specificity protein ( 184) 686 143.0 3.3e-34
XP_011513059 (OMIM: 616778) PREDICTED: dual specif ( 145) 412 89.5 3.3e-18
XP_016866551 (OMIM: 616778) PREDICTED: dual specif ( 124) 411 89.3 3.3e-18
XP_005261425 (OMIM: 611446) PREDICTED: dual specif ( 188) 310 69.7 3.9e-12
NP_001291723 (OMIM: 611446) dual specificity prote ( 188) 310 69.7 3.9e-12
XP_011528222 (OMIM: 611446) PREDICTED: dual specif ( 188) 310 69.7 3.9e-12
XP_016884117 (OMIM: 611446) PREDICTED: dual specif ( 188) 310 69.7 3.9e-12
XP_006724211 (OMIM: 611446) PREDICTED: dual specif ( 188) 310 69.7 3.9e-12
NP_001291724 (OMIM: 611446) dual specificity prote ( 188) 310 69.7 3.9e-12
XP_011528223 (OMIM: 611446) PREDICTED: dual specif ( 188) 310 69.7 3.9e-12
NP_689724 (OMIM: 611446) dual specificity protein ( 188) 310 69.7 3.9e-12
XP_016884116 (OMIM: 611446) PREDICTED: dual specif ( 188) 310 69.7 3.9e-12
NP_009138 (OMIM: 608867) dual specificity protein ( 482) 311 70.2 7.1e-12
NP_543152 (OMIM: 611437) dual specificity protein ( 217) 306 69.0 7.5e-12
XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625) 306 69.3 1.7e-11
XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625) 306 69.3 1.7e-11
NP_004411 (OMIM: 602038) dual specificity protein ( 625) 306 69.3 1.7e-11
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 300 68.0 2.6e-11
XP_016873431 (OMIM: 606780) PREDICTED: protein pho ( 559) 297 67.5 5.3e-11
NP_060327 (OMIM: 606780) protein phosphatase Sling ( 659) 297 67.6 6e-11
XP_016883149 (OMIM: 616776) PREDICTED: dual specif ( 232) 290 65.9 6.8e-11
XP_016883148 (OMIM: 616776) PREDICTED: dual specif ( 232) 290 65.9 6.8e-11
XP_016883150 (OMIM: 616776) PREDICTED: dual specif ( 232) 290 65.9 6.8e-11
XP_016883147 (OMIM: 616776) PREDICTED: dual specif ( 232) 290 65.9 6.8e-11
XP_016883151 (OMIM: 616776) PREDICTED: dual specif ( 232) 290 65.9 6.8e-11
NP_009171 (OMIM: 604835) dual specificity protein ( 340) 292 66.4 7e-11
XP_011535410 (OMIM: 615814) PREDICTED: serine/thre ( 199) 287 65.2 9.1e-11
NP_660294 (OMIM: 615814) serine/threonine/tyrosine ( 223) 287 65.3 1e-10
NP_001124173 (OMIM: 615814) serine/threonine/tyros ( 223) 287 65.3 1e-10
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 288 65.8 2e-10
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 288 65.8 2e-10
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 288 65.8 2e-10
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 288 65.8 2e-10
XP_005257034 (OMIM: 606618) PREDICTED: dual specif ( 198) 271 62.1 7.9e-10
XP_011522536 (OMIM: 606618) PREDICTED: dual specif ( 198) 271 62.1 7.9e-10
NP_008957 (OMIM: 606618) dual specificity protein ( 198) 271 62.1 7.9e-10
NP_071359 (OMIM: 300678) dual specificity protein ( 190) 267 61.3 1.3e-09
NP_004408 (OMIM: 600714) dual specificity protein ( 367) 268 61.7 1.9e-09
NP_004409 (OMIM: 603068) dual specificity protein ( 314) 265 61.1 2.5e-09
XP_016859035 (OMIM: 603068) PREDICTED: dual specif ( 342) 265 61.1 2.7e-09
>>NP_542178 (OMIM: 616776) dual specificity protein phos (235 aa)
initn: 1604 init1: 1604 opt: 1604 Z-score: 1701.1 bits: 322.1 E(85289): 5.2e-88
Smith-Waterman score: 1604; 99.6% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
130 140 150 160 170 180
190 200 210 220 230
pF1KE5 TSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_542 TSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
190 200 210 220 230
>>NP_001307407 (OMIM: 616776) dual specificity protein p (232 aa)
initn: 1556 init1: 1556 opt: 1557 Z-score: 1651.6 bits: 312.9 E(85289): 2.9e-85
Smith-Waterman score: 1557; 98.7% identity (99.6% similar) in 232 aa overlap (5-235:1-232)
10 20 30 40 50
pF1KE5 MGNGMTK-VLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
::. ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 ATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 ATSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_001 ATSASSAGPHSAASEGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
180 190 200 210 220 230
>>XP_016883146 (OMIM: 616776) PREDICTED: dual specificit (298 aa)
initn: 1000 init1: 1000 opt: 1000 Z-score: 1063.2 bits: 204.4 E(85289): 1.8e-52
Smith-Waterman score: 1000; 98.0% identity (98.7% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
::::::::::::::::::::::::: :.
XP_016 TRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAAL
130 140 150 160 170 180
>>XP_016883145 (OMIM: 616776) PREDICTED: dual specificit (311 aa)
initn: 1016 init1: 998 opt: 999 Z-score: 1061.8 bits: 204.2 E(85289): 2.1e-52
Smith-Waterman score: 999; 88.4% identity (91.9% similar) in 172 aa overlap (1-170:1-171)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQL--EERFGESPFRDEEELRALLPLCKRCRQG
::::::::::::::::::::::::: . :.. : : : .. .:::
XP_016 TRPIANPNPGFRQQLEEFGWASSQKDGSGFATEDEDKEWPHRLAQQ-GSLLPPILLQALW
130 140 150 160 170
180 190 200 210 220 230
pF1KE5 SATSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
XP_016 LTTGARHRTSKTSGAQCPPMTSATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAER
180 190 200 210 220 230
>>XP_016883143 (OMIM: 616776) PREDICTED: dual specificit (335 aa)
initn: 998 init1: 998 opt: 999 Z-score: 1061.4 bits: 204.2 E(85289): 2.2e-52
Smith-Waterman score: 999; 88.4% identity (91.9% similar) in 172 aa overlap (1-170:1-171)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQL--EERFGESPFRDEEELRALLPLCKRCRQG
::::::::::::::::::::::::: . :.. : : : .. .:::
XP_016 TRPIANPNPGFRQQLEEFGWASSQKDGSGFATEDEDKEWPHRLAQQ-GSLLPPILLQALW
130 140 150 160 170
180 190 200 210 220 230
pF1KE5 SATSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
XP_016 LTTGARHRTSKTSGAQCPPMTSATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAER
180 190 200 210 220 230
>>NP_001307408 (OMIM: 616776) dual specificity protein p (295 aa)
initn: 952 init1: 952 opt: 953 Z-score: 1013.7 bits: 195.2 E(85289): 1e-49
Smith-Waterman score: 953; 96.6% identity (97.9% similar) in 146 aa overlap (5-149:1-146)
10 20 30 40 50
pF1KE5 MGNGMTK-VLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
::. ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 ATRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGS
:::::::::::::::::::::::::: :.
NP_001 ATRPIANPNPGFRQQLEEFGWASSQKGARHRTSKTSGAQCPPMTSATCLLAARVALLSAA
120 130 140 150 160 170
>>XP_016883144 (OMIM: 616776) PREDICTED: dual specificit (332 aa)
initn: 950 init1: 950 opt: 952 Z-score: 1011.9 bits: 195.1 E(85289): 1.3e-49
Smith-Waterman score: 952; 87.0% identity (91.1% similar) in 169 aa overlap (5-170:1-168)
10 20 30 40 50
pF1KE5 MGNGMTK-VLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
::. ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEGVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTP
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 ATRPIANPNPGFRQQLEEFGWASSQKLRRQL--EERFGESPFRDEEELRALLPLCKRCRQ
:::::::::::::::::::::::::: . :.. : : : .. .:::
XP_016 ATRPIANPNPGFRQQLEEFGWASSQKDGSGFATEDEDKEWPHRLAQQ-GSLLPPILLQAL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 GSATSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
XP_016 WLTTGARHRTSKTSGAQCPPMTSATCLLAARVALLSAALVREATGRTAQRCRLSPRAAAE
180 190 200 210 220 230
>>NP_001012662 (OMIM: 616776) dual specificity protein p (132 aa)
initn: 895 init1: 895 opt: 895 Z-score: 957.5 bits: 183.7 E(85289): 1.4e-46
Smith-Waterman score: 895; 99.2% identity (100.0% similar) in 132 aa overlap (104-235:1-132)
80 90 100 110 120 130
pF1KE5 IHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQ
::::::::::::::::::::::::::::::
NP_001 MTVTGLGWRDVLEAIKATRPIANPNPGFRQ
10 20 30
140 150 160 170 180 190
pF1KE5 QLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAAS
40 50 60 70 80 90
200 210 220 230
pF1KE5 EGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
:::.::::::::::::::::::::::::::::::::::::::
NP_001 EGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
100 110 120 130
>>NP_817130 (OMIM: 616776) dual specificity protein phos (132 aa)
initn: 895 init1: 895 opt: 895 Z-score: 957.5 bits: 183.7 E(85289): 1.4e-46
Smith-Waterman score: 895; 99.2% identity (100.0% similar) in 132 aa overlap (104-235:1-132)
80 90 100 110 120 130
pF1KE5 IHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRPIANPNPGFRQ
::::::::::::::::::::::::::::::
NP_817 MTVTGLGWRDVLEAIKATRPIANPNPGFRQ
10 20 30
140 150 160 170 180 190
pF1KE5 QLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 QLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSATSASSAGPHSAAS
40 50 60 70 80 90
200 210 220 230
pF1KE5 EGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
:::.::::::::::::::::::::::::::::::::::::::
NP_817 EGTVQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
100 110 120 130
>>NP_001273484 (OMIM: 616778) dual specificity protein p (205 aa)
initn: 686 init1: 686 opt: 687 Z-score: 735.6 bits: 143.3 E(85289): 3.1e-34
Smith-Waterman score: 687; 53.9% identity (80.3% similar) in 178 aa overlap (1-178:1-176)
10 20 30 40 50 60
pF1KE5 MGNGMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHESPQPLLQDITYLRIPVADTPE
:::::.:.:::::.::: ::.: .::..::.:::.:.:.: .:.:. . :: ::.::.:
NP_001 MGNGMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEGVKYLCIPAADSPS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VPIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKA
. .:::: :.::: ::: : .:::::.::.:::.:.: ::.:::: .::.:.:....:
NP_001 QNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSA
: :::: ::..::.:: .. :. :.:..::::..: :: . .: : .::
NP_001 GRSCANPNVGFQRQLQEFEKHEVHQYRQWLKEEYGESPLQDAEEAKNILG--KYKEQGRT
130 140 150 160 170
190 200 210 220 230
pF1KE5 TSASSAGPHSAASEGTLQRLVPRTPREAHRPLPLLARVKQTFSCLPRCLSRKGGK
NP_001 EPQPGARRWSSFPALAPLTYDNYTTET
180 190 200
235 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:21:30 2016 done: Mon Nov 7 23:21:31 2016
Total Scan time: 6.830 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]