Result of FASTA (omim) for
pFN21AE5262
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5262, 179 aa
1>>>pF1KE5262 179 - 179 aa - 179 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8867+/-0.0003; mu= 15.2171+/- 0.019
mean_var=60.5044+/-12.675, 0's: 0 Z-trim(116.6): 24 B-trim: 1623 in 2/53
Lambda= 0.164885
statistics sampled from 27947 (27971) to 27947 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.328), width: 16
Scan time: 4.080
The best scores are: opt bits E(85289)
NP_945192 (OMIM: 600312) 7,8-dihydro-8-oxoguanine ( 179) 1254 306.1 2e-83
NP_945190 (OMIM: 600312) 7,8-dihydro-8-oxoguanine ( 179) 1254 306.1 2e-83
NP_945187 (OMIM: 600312) 7,8-dihydro-8-oxoguanine ( 179) 1254 306.1 2e-83
NP_002443 (OMIM: 600312) 7,8-dihydro-8-oxoguanine ( 156) 1086 266.1 1.9e-71
NP_945186 (OMIM: 600312) 7,8-dihydro-8-oxoguanine ( 156) 1086 266.1 1.9e-71
NP_945191 (OMIM: 600312) 7,8-dihydro-8-oxoguanine ( 156) 1086 266.1 1.9e-71
NP_945188 (OMIM: 600312) 7,8-dihydro-8-oxoguanine ( 156) 1086 266.1 1.9e-71
NP_060753 (OMIM: 615792,616903) probable 8-oxo-dGT ( 164) 162 46.3 2.9e-05
NP_001287670 (OMIM: 609232) peroxisomal NADH pyrop ( 444) 147 43.0 0.00078
XP_005272154 (OMIM: 609232) PREDICTED: peroxisomal ( 444) 147 43.0 0.00078
NP_113626 (OMIM: 609232) peroxisomal NADH pyrophos ( 462) 147 43.0 0.00081
XP_005272152 (OMIM: 609232) PREDICTED: peroxisomal ( 462) 147 43.0 0.00081
NP_001291674 (OMIM: 615792,616903) probable 8-oxo- ( 145) 140 41.0 0.001
>>NP_945192 (OMIM: 600312) 7,8-dihydro-8-oxoguanine trip (179 aa)
initn: 1254 init1: 1254 opt: 1254 Z-score: 1618.7 bits: 306.1 E(85289): 2e-83
Smith-Waterman score: 1254; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
130 140 150 160 170
>>NP_945190 (OMIM: 600312) 7,8-dihydro-8-oxoguanine trip (179 aa)
initn: 1254 init1: 1254 opt: 1254 Z-score: 1618.7 bits: 306.1 E(85289): 2e-83
Smith-Waterman score: 1254; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
130 140 150 160 170
>>NP_945187 (OMIM: 600312) 7,8-dihydro-8-oxoguanine trip (179 aa)
initn: 1254 init1: 1254 opt: 1254 Z-score: 1618.7 bits: 306.1 E(85289): 2e-83
Smith-Waterman score: 1254; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
130 140 150 160 170
>>NP_002443 (OMIM: 600312) 7,8-dihydro-8-oxoguanine trip (156 aa)
initn: 1086 init1: 1086 opt: 1086 Z-score: 1403.6 bits: 266.1 E(85289): 1.9e-71
Smith-Waterman score: 1086; 100.0% identity (100.0% similar) in 156 aa overlap (24-179:1-156)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
:::::::::::::::::::::::::::::::::::::
NP_002 MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
10 20 30
70 80 90 100 110 120
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
40 50 60 70 80 90
130 140 150 160 170
pF1KE5 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
100 110 120 130 140 150
>>NP_945186 (OMIM: 600312) 7,8-dihydro-8-oxoguanine trip (156 aa)
initn: 1086 init1: 1086 opt: 1086 Z-score: 1403.6 bits: 266.1 E(85289): 1.9e-71
Smith-Waterman score: 1086; 100.0% identity (100.0% similar) in 156 aa overlap (24-179:1-156)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
:::::::::::::::::::::::::::::::::::::
NP_945 MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
10 20 30
70 80 90 100 110 120
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
40 50 60 70 80 90
130 140 150 160 170
pF1KE5 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
100 110 120 130 140 150
>>NP_945191 (OMIM: 600312) 7,8-dihydro-8-oxoguanine trip (156 aa)
initn: 1086 init1: 1086 opt: 1086 Z-score: 1403.6 bits: 266.1 E(85289): 1.9e-71
Smith-Waterman score: 1086; 100.0% identity (100.0% similar) in 156 aa overlap (24-179:1-156)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
:::::::::::::::::::::::::::::::::::::
NP_945 MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
10 20 30
70 80 90 100 110 120
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
40 50 60 70 80 90
130 140 150 160 170
pF1KE5 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
100 110 120 130 140 150
>>NP_945188 (OMIM: 600312) 7,8-dihydro-8-oxoguanine trip (156 aa)
initn: 1086 init1: 1086 opt: 1086 Z-score: 1403.6 bits: 266.1 E(85289): 1.9e-71
Smith-Waterman score: 1086; 100.0% identity (100.0% similar) in 156 aa overlap (24-179:1-156)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
:::::::::::::::::::::::::::::::::::::
NP_945 MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
10 20 30
70 80 90 100 110 120
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVE
40 50 60 70 80 90
130 140 150 160 170
pF1KE5 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_945 SDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
100 110 120 130 140 150
>>NP_060753 (OMIM: 615792,616903) probable 8-oxo-dGTP di (164 aa)
initn: 154 init1: 119 opt: 162 Z-score: 215.4 bits: 46.3 E(85289): 2.9e-05
Smith-Waterman score: 162; 27.5% identity (57.7% similar) in 149 aa overlap (18-161:9-150)
10 20 30 40 50 60
pF1KE5 MSGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGG
:. :: .:.. . : .:. :::: .: . ::: .. ::
NP_060 MTASAQPRGRRPG-VGVGVVVTSC--KHPRCVLLGKRKGSVGAGSFQLPGG
10 20 30 40
70 80 90 100 110
pF1KE5 KVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGT-PV
... ::: :. :.:: ::..: . .: ...: :. . . : .. .. :
NP_060 HLEFGETWEECAQRETWEEAALHLKNVH-FASVVNSFIEKENYHYVTILMKGEVDVTHDS
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 ESDEMRP----CWFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLRE
: ...: : . .:.... : :. .. : :.. . ::
NP_060 EPKNVEPEKNESW---EWVPWEELPPLDQLFWGLRCLKEQGYDPFKEDLNHLVGYKGNHL
110 120 130 140 150 160
pF1KE5 VDTV
>>NP_001287670 (OMIM: 609232) peroxisomal NADH pyrophosp (444 aa)
initn: 130 init1: 93 opt: 147 Z-score: 189.8 bits: 43.0 E(85289): 0.00078
Smith-Waterman score: 147; 31.8% identity (61.8% similar) in 110 aa overlap (32-134:308-409)
10 20 30 40 50
pF1KE5 SGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQ--RVLLGMKKRGFGAGRWNGFG
.. :..:. . ::: .:: : : .. ..
NP_001 GGYKRLCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKR-FPPGMFTCLA
280 290 300 310 320 330
60 70 80 90 100 110
pF1KE5 GKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELM--DVHVFCTDSIQGT
: .. ::::::..:::..::::. :::.. . . .: : .. . : .:
NP_001 GFIEPGETIEDAVRREVEEESGV------KVGHVQY-VACQPWPMPSSLMIGCLALAVST
340 350 360 370 380
120 130 140 150 160 170
pF1KE5 PVESD--EMRPC-WFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLR
.. : :.. :: .:.
NP_001 EIKVDKNEIEDARWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
390 400 410 420 430 440
>>XP_005272154 (OMIM: 609232) PREDICTED: peroxisomal NAD (444 aa)
initn: 130 init1: 93 opt: 147 Z-score: 189.8 bits: 43.0 E(85289): 0.00078
Smith-Waterman score: 147; 31.8% identity (61.8% similar) in 110 aa overlap (32-134:308-409)
10 20 30 40 50
pF1KE5 SGISPQQMGEPEGSWSGKNPGTMGASRLYTLVLVLQPQ--RVLLGMKKRGFGAGRWNGFG
.. :..:. . ::: .:: : : .. ..
XP_005 GGYKRLCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKR-FPPGMFTCLA
280 290 300 310 320 330
60 70 80 90 100 110
pF1KE5 GKVQEGETIEDGARRELQEESGLTVDALHKVGQIVFEFVGEPELM--DVHVFCTDSIQGT
: .. ::::::..:::..::::. :::.. . . .: : .. . : .:
XP_005 GFIEPGETIEDAVRREVEEESGV------KVGHVQY-VACQPWPMPSSLMIGCLALAVST
340 350 360 370 380
120 130 140 150 160 170
pF1KE5 PVESD--EMRPC-WFQLDQIPFKDMWPDDSYWFPLLLQKKKFHGYFKFQGQDTILDYTLR
.. : :.. :: .:.
XP_005 EIKVDKNEIEDARWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
390 400 410 420 430 440
179 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:59:17 2016 done: Mon Nov 7 22:59:17 2016
Total Scan time: 4.080 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]