Result of FASTA (ccds) for
pFN21AE5234
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5234, 211 aa
1>>>pF1KE5234 211 - 211 aa - 211 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5580+/-0.000843; mu= 11.4870+/- 0.050
mean_var=68.0375+/-13.326, 0's: 0 Z-trim(106.8): 67 B-trim: 90 in 1/48
Lambda= 0.155489
statistics sampled from 9112 (9189) to 9112 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.282), width: 16
Scan time: 1.400
The best scores are: opt bits E(32554)
CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 1431 329.9 7.3e-91
CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 656 156.0 1.4e-38
CCDS31223.1 DUPD1 gene_id:338599|Hs108|chr10 ( 220) 584 139.9 1.2e-33
CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 ( 198) 567 136.0 1.5e-32
CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 ( 248) 568 136.3 1.6e-32
CCDS30932.1 DUSP27 gene_id:92235|Hs108|chr1 (1158) 486 118.2 2.1e-26
CCDS11469.1 DUSP3 gene_id:1845|Hs108|chr17 ( 185) 408 100.3 7.9e-22
CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 307 77.7 5.5e-15
CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 ( 314) 308 78.0 7e-15
CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 296 75.4 5.4e-14
CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 293 74.7 8.3e-14
CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 282 72.1 2.5e-13
CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 282 72.1 2.8e-13
CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 284 72.6 2.8e-13
CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 284 72.7 3.6e-13
CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX ( 384) 283 72.5 4.1e-13
CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 273 70.3 3.1e-12
CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 270 69.6 3.8e-12
CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 263 67.8 4.9e-12
CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 255 66.1 2.1e-11
CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 251 65.2 3.8e-11
CCDS55882.1 SSH1 gene_id:54434|Hs108|chr12 ( 692) 257 66.7 3.9e-11
CCDS53825.1 SSH1 gene_id:54434|Hs108|chr12 ( 703) 257 66.7 3.9e-11
CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 256 66.5 4.4e-11
CCDS9121.1 SSH1 gene_id:54434|Hs108|chr12 (1049) 257 66.8 5.5e-11
CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX ( 190) 244 63.6 9.6e-11
>>CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 (211 aa)
initn: 1431 init1: 1431 opt: 1431 Z-score: 1744.7 bits: 329.9 E(32554): 7.3e-91
Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 211 aa overlap (1-211:1-211)
10 20 30 40 50 60
pF1KE5 MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 HADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 HADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS60 SPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIK
130 140 150 160 170 180
190 200 210
pF1KE5 KVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
:::::::::::::::::::::::::::::::
CCDS60 KVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
190 200 210
>>CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 (188 aa)
initn: 641 init1: 431 opt: 656 Z-score: 805.9 bits: 156.0 E(32554): 1.4e-38
Smith-Waterman score: 656; 58.9% identity (83.3% similar) in 168 aa overlap (41-206:17-183)
20 30 40 50 60 70
pF1KE5 MTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTACNHADEVWPGLY
: ...:::.:: .::..:...:::::.:.
CCDS53 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLF
10 20 30 40
80 90 100 110 120
pF1KE5 LGDQDMANNRRELRRLGITHVLNASHSRW--RGTPEAYEGLGIRYLGVEAHDSPAFDMSI
.:: :::: :: .:::::::::.:. .: :. : : .. :::: ::: : ::.:
CCDS53 IGDAATANNRFELWKLGITHVLNAAHKGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 HFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGI
.:..:::::::::. ::.:.::::.::::::::::::::::...:.: .:. :..:: .
CCDS53 YFSSAADFIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWV
110 120 130 140 150 160
190 200 210
pF1KE5 IPNRGFLRQLLALDRRLRQGLEA
.::::::.:: ::..::
CCDS53 FPNRGFLHQLCRLDQQLRGAGQS
170 180
>>CCDS31223.1 DUPD1 gene_id:338599|Hs108|chr10 (220 aa)
initn: 574 init1: 360 opt: 584 Z-score: 717.6 bits: 139.9 E(32554): 1.2e-33
Smith-Waterman score: 584; 49.5% identity (74.7% similar) in 194 aa overlap (17-207:14-202)
10 20 30 40 50
pF1KE5 MCPGNWLWASMTFMARFSRSSSRSP-VRTRGTLEEMPTVQHPFLNVFELERLLYTGKTAC
.: .. :: .. .: :.. : : ..::::::.. :.
CCDS31 MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCT---P--GAFELERLFWKGSPQY
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWR--GTPEAYEGLGIRYLGVE
.:..:::: ::.::. : .: .:.. :.::::::.:.:: :. :. . :.: :::
CCDS31 THVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVE
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 AHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVE
: : :.::.:. : :: :: ::::. .::::::..: ::::::::::::... .:::.
CCDS31 ADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVD
120 130 140 150 160 170
180 190 200 210
pF1KE5 AIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
::..: .: ..::::::.:: ::..: :
CCDS31 AIQQVAKNRCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL
180 190 200 210 220
>>CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 (198 aa)
initn: 553 init1: 399 opt: 567 Z-score: 697.7 bits: 136.0 E(32554): 1.5e-32
Smith-Waterman score: 567; 48.2% identity (74.9% similar) in 195 aa overlap (14-205:1-191)
10 20 30 40 50
pF1KE5 MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTAC-
: ..... : : . .:... : : : : :.:::.. ..:
CCDS73 MDSLQKQDLRRP-KIHGAVQASP-YQPPTLA--SLQRLLWVRQAATL
10 20 30 40
60 70 80 90 100 110
pF1KE5 NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEA--YEGLGIRYLGVE
:: :::::.:.::: : .. .: .::::::.::. .... : :.:....: :.:
CCDS73 NHIDEVWPSLFLGDAYAARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE5 AHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVE
: :.: ::.:..: .: .:. ::: : :..:::::.:::::::::::.::. ...::::
CCDS73 ADDNPFFDLSVYFLPVARYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVE
110 120 130 140 150 160
180 190 200 210
pF1KE5 AIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
::. :. ::.: :: :::::: .:: ::
CCDS73 AIQTVQAHRNICPNSGFLRQLQVLDNRLGRETGRF
170 180 190
>>CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 (248 aa)
initn: 675 init1: 399 opt: 568 Z-score: 697.4 bits: 136.3 E(32554): 1.6e-32
Smith-Waterman score: 568; 46.3% identity (73.7% similar) in 205 aa overlap (7-205:41-241)
10 20 30
pF1KE5 MCPGNWLWASMTF---MARFSRSSSRSPVRTRGTLE
.: .. . : ..... : : . .:...
CCDS31 GEDKATPCPSILELEELLRAGKSSCSRVDEVWPNLFIGDAMDSLQKQDLRRP-KIHGAVQ
20 30 40 50 60
40 50 60 70 80 90
pF1KE5 EMPTVQHPFLNVFELERLLYTGKTAC-NHADEVWPGLYLGDQDMANNRRELRRLGITHVL
: : : : :.:::.. ..: :: :::::.:.::: : .. .: .::::::.
CCDS31 ASP-YQPPTLA--SLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 NASHSRWRGTPEA--YEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILV
::. .... : :.:....: :.:: :.: ::.:..: .: .:. ::: : :..::
CCDS31 NAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRVLV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 HCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLE
:::.:::::::::::.::. ...::::::. :. ::.: :: :::::: .:: ::
CCDS31 HCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRETG
190 200 210 220 230 240
pF1KE5 A
CCDS31 RF
>>CCDS30932.1 DUSP27 gene_id:92235|Hs108|chr1 (1158 aa)
initn: 469 init1: 338 opt: 486 Z-score: 587.6 bits: 118.2 E(32554): 2.1e-26
Smith-Waterman score: 486; 42.9% identity (73.1% similar) in 182 aa overlap (27-205:99-278)
10 20 30 40 50
pF1KE5 MCPGNWLWASMTFMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGK
:.: ... . : :..:.: : .
CCDS30 ELKPPGVRADAECPGMLESAEQLLVEDLYNRVREKMDDTSLYNTPC--VLDLQRALVQDR
70 80 90 100 110 120
60 70 80 90 100 110
pF1KE5 TAC--NHADEVWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGT-PEAYEGLGIRY
:..:::::.........: :. .:.::::::.:::.:. : :: : :: :.:
CCDS30 QEAPWNEVDEVWPNVFIAEKSVAVNKGRLKRLGITHILNAAHGTGVYTGPEFYTGLEIQY
130 140 150 160 170 180
120 130 140 150 160 170
pF1KE5 LGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHL
::::. : : :.: ::. :..:. .:: ::.:: .:.::::.::.::::..:..
CCDS30 LGVEVDDFPEVDISQHFRKASEFLDEALLTYRGKVLVSSEMGISRSAVLVVAYLMIFHNM
190 200 210 220 230 240
180 190 200 210
pF1KE5 TLVEAIKKVKDHRGIIPNRGFLRQLLALDRRLRQGLEA
...::. :. .:.: ::.:::.:: :...:
CCDS30 AILEALMTVRKKRAIYPNEGFLKQLRELNEKLMEEREEDYGREGGSAEAEEGEGTGSMLG
250 260 270 280 290 300
CCDS30 ARVHALTVEEEDDSASHLSGSSLGKATQASKPLTLIDEEEEEKLYEQWKKGQGLLSDKVP
310 320 330 340 350 360
>>CCDS11469.1 DUSP3 gene_id:1845|Hs108|chr17 (185 aa)
initn: 416 init1: 321 opt: 408 Z-score: 505.4 bits: 100.3 E(32554): 7.9e-22
Smith-Waterman score: 412; 42.0% identity (70.5% similar) in 176 aa overlap (43-208:7-181)
20 30 40 50 60
pF1KE5 FMARFSRSSSRSPVRTRGTLEEMPTVQHPFLNVFELERLLYTGKTAC-----NHADEVWP
:.: .:. :: : ..: . .:: :
CCDS11 MSGSFELSVQDLNDLLSDG-SGCYSLPSQPCNEVTP
10 20 30
70 80 90 100 110 120
pF1KE5 GLYLGDQDMANNRRELRRLGITHVLNASHSR----WRGTPEAYEGLGIRYLGVEAHDSPA
.:.:. ..:.. .:..:::::::::...: . . :. :: :::..:.:.
CCDS11 RIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 FDMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVK
:..: .:. ::::: .::.: .:..:::: : ::: :::.::::. ... . :.. :.
CCDS11 FNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVR
100 110 120 130 140 150
190 200 210
pF1KE5 DHRGIIPNRGFLRQLLALDRRL-RQGLEA
..: : :: ::: :: :. :: ..:
CCDS11 QNREIGPNDGFLAQLCQLNDRLAKEGKLKP
160 170 180
>>CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 (198 aa)
initn: 253 init1: 157 opt: 307 Z-score: 382.5 bits: 77.7 E(32554): 5.5e-15
Smith-Waterman score: 307; 41.3% identity (68.5% similar) in 143 aa overlap (64-205:29-165)
40 50 60 70 80 90
pF1KE5 EMPTVQHPFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLN
.. .:.:: ..:.::. :. ::: ..:
CCDS11 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVN
10 20 30 40 50
100 110 120 130 140 150
pF1KE5 ASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCA
:. :. .. ..:. : : : ....:.:.:: :: ..:. : :::::
CCDS11 ATIE----IPN-FNWPQFEYVKVPLADMPHAPIGLYFDTVADKIH-SVSRKHGATLVHCA
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE5 VGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGII-PNRGFLRQLLALDRRLRQGLEA
.:::::::: .:::: .:.. :.:: . :: .: .: :: :: :::. .:.:
CCDS11 AGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVK
120 130 140 150 160 170
CCDS11 MVQTPYGIVPDVYEKESRHLMPYWGI
180 190
>>CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 (314 aa)
initn: 280 init1: 163 opt: 308 Z-score: 380.6 bits: 78.0 E(32554): 7e-15
Smith-Waterman score: 308; 40.6% identity (69.2% similar) in 143 aa overlap (64-205:175-311)
40 50 60 70 80 90
pF1KE5 EMPTVQHPFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLN
:. : :.::. . ... . :. ::: :::
CCDS20 EAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLN
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 ASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCA
.: : :. .::: .:: .. ..:. ..: :: : :: ... ::..::::
CCDS20 VSAS----CPNHFEGL-FRYKSIPVEDNQMVEISAWFQEAIGFIDW-VKNSGGRVLVHCQ
210 220 230 240 250
160 170 180 190 200 210
pF1KE5 VGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGII-PNRGFLRQLLALDRRLRQGLEA
.:.:::::. ::::: ... : ::. ::..::.: :: .:. ::: .. ..
CCDS20 AGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
260 270 280 290 300 310
>>CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 (384 aa)
initn: 244 init1: 149 opt: 296 Z-score: 364.7 bits: 75.4 E(32554): 5.4e-14
Smith-Waterman score: 296; 40.6% identity (65.7% similar) in 143 aa overlap (64-205:181-317)
40 50 60 70 80 90
pF1KE5 EMPTVQHPFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRRELRRLGITHVLN
:. : ::::. :.. . : : :: .::
CCDS75 IESERALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLN
160 170 180 190 200 210
100 110 120 130 140 150
pF1KE5 ASHSRWRGTPEAYEGLGIRYLGVEAHDSPAFDMSIHFQTAADFIHRALSQPGGKILVHCA
.: : : :: . ..: . ..:: . :.: ::: : ::: . . :::.::::
CCDS75 VS----RRTSEAC-ATHLHYKWIPVEDSHTADISSHFQEAIDFID-CVREKGGKVLVHCE
220 230 240 250 260
160 170 180 190 200 210
pF1KE5 VGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRGII-PNRGFLRQLLALDRRLRQGLEA
.:.::: :. .:::: ... : ::. .:..:... :: ::. ::: . ..
CCDS75 AGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNP
270 280 290 300 310 320
CCDS75 QPPSCQGEAAGSSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC
330 340 350 360 370 380
211 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:45:11 2016 done: Mon Nov 7 22:45:11 2016
Total Scan time: 1.400 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]