Result of FASTA (omim) for
pFN21AE5225
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5225, 250 aa
1>>>pF1KE5225 250 - 250 aa - 250 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6307+/-0.00033; mu= 6.9711+/- 0.021
mean_var=175.1575+/-34.290, 0's: 0 Z-trim(121.7): 6 B-trim: 0 in 0/57
Lambda= 0.096908
statistics sampled from 38744 (38750) to 38744 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.454), width: 16
Scan time: 5.480
The best scores are: opt bits E(85289)
NP_001019195 (OMIM: 128230,233910,600225) GTP cycl ( 250) 1673 244.9 9.8e-65
NP_000152 (OMIM: 128230,233910,600225) GTP cyclohy ( 250) 1673 244.9 9.8e-65
NP_001019241 (OMIM: 128230,233910,600225) GTP cycl ( 233) 1413 208.6 8.2e-54
NP_001019242 (OMIM: 128230,233910,600225) GTP cycl ( 213) 1407 207.7 1.4e-53
XP_016876707 (OMIM: 128230,233910,600225) PREDICTE ( 152) 875 133.2 2.6e-31
>>NP_001019195 (OMIM: 128230,233910,600225) GTP cyclohyd (250 aa)
initn: 1673 init1: 1673 opt: 1673 Z-score: 1283.1 bits: 244.9 E(85289): 9.8e-65
Smith-Waterman score: 1673; 100.0% identity (100.0% similar) in 250 aa overlap (1-250:1-250)
10 20 30 40 50 60
pF1KE5 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKT
190 200 210 220 230 240
250
pF1KE5 REEFLTLIRS
::::::::::
NP_001 REEFLTLIRS
250
>>NP_000152 (OMIM: 128230,233910,600225) GTP cyclohydrol (250 aa)
initn: 1673 init1: 1673 opt: 1673 Z-score: 1283.1 bits: 244.9 E(85289): 9.8e-65
Smith-Waterman score: 1673; 100.0% identity (100.0% similar) in 250 aa overlap (1-250:1-250)
10 20 30 40 50 60
pF1KE5 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKT
190 200 210 220 230 240
250
pF1KE5 REEFLTLIRS
::::::::::
NP_000 REEFLTLIRS
250
>>NP_001019241 (OMIM: 128230,233910,600225) GTP cyclohyd (233 aa)
initn: 1407 init1: 1407 opt: 1413 Z-score: 1087.1 bits: 208.6 E(85289): 8.2e-54
Smith-Waterman score: 1413; 94.6% identity (96.9% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE5 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKT
:::::::::::::::::::::::::::::. .:.. . :
NP_001 VQERLTKQIAVAITEALRPAGVGVVVEATKSNKYNKGLSPLLSSCHLFVAILK
190 200 210 220 230
250
pF1KE5 REEFLTLIRS
>>NP_001019242 (OMIM: 128230,233910,600225) GTP cyclohyd (213 aa)
initn: 1407 init1: 1407 opt: 1407 Z-score: 1083.1 bits: 207.7 E(85289): 1.4e-53
Smith-Waterman score: 1407; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209)
10 20 30 40 50 60
pF1KE5 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEKGPVRAPAEKPRGARCSNGFPERDPPRPGPSRPAEKPPRPEAKSAQPADGWKGERPRS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDNELNLPNLAAAYSSILSSLGENPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFDEDHDEMVIVKDIDMFSMCEHHLVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VQERLTKQIAVAITEALRPAGVGVVVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKT
:::::::::::::::::::::::::::::
NP_001 VQERLTKQIAVAITEALRPAGVGVVVEATSAEP
190 200 210
>>XP_016876707 (OMIM: 128230,233910,600225) PREDICTED: G (152 aa)
initn: 875 init1: 875 opt: 875 Z-score: 683.1 bits: 133.2 E(85289): 2.6e-31
Smith-Waterman score: 875; 100.0% identity (100.0% similar) in 136 aa overlap (115-250:17-152)
90 100 110 120 130 140
pF1KE5 NPQRQGLLKTPWRAASAMQFFTKGYQETISDVLNDAIFDEDHDEMVIVKDIDMFSMCEHH
::::::::::::::::::::::::::::::
XP_016 MFGFMLILAKFSKFCLDVLNDAIFDEDHDEMVIVKDIDMFSMCEHH
10 20 30 40
150 160 170 180 190 200
pF1KE5 LVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVPFVGKVHIGYLPNKQVLGLSKLARIVEIYSRRLQVQERLTKQIAVAITEALRPAGVGV
50 60 70 80 90 100
210 220 230 240 250
pF1KE5 VVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVEATHMCMVMRGVQKMNSKTVTSTMLGVFREDPKTREEFLTLIRS
110 120 130 140 150
250 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:40:32 2016 done: Mon Nov 7 22:40:33 2016
Total Scan time: 5.480 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]