Result of FASTA (omim) for
pFN21AE5212
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5212, 185 aa
1>>>pF1KE5212 185 - 185 aa - 185 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0311+/-0.000413; mu= 8.4869+/- 0.025
mean_var=76.4991+/-15.517, 0's: 0 Z-trim(112.3): 147 B-trim: 401 in 1/52
Lambda= 0.146638
statistics sampled from 20942 (21126) to 20942 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.248), width: 16
Scan time: 4.960
The best scores are: opt bits E(85289)
NP_004081 (OMIM: 600183) dual specificity protein ( 185) 1217 266.9 1.3e-71
NP_001007272 (OMIM: 613191) dual specificity prote ( 188) 465 107.8 1e-23
NP_001307772 (OMIM: 613191) dual specificity prote ( 198) 430 100.4 1.8e-21
XP_011538158 (OMIM: 613191) PREDICTED: dual specif ( 198) 430 100.4 1.8e-21
XP_011538156 (OMIM: 613191) PREDICTED: dual specif ( 198) 430 100.4 1.8e-21
XP_011538157 (OMIM: 613191) PREDICTED: dual specif ( 198) 430 100.4 1.8e-21
XP_005269947 (OMIM: 613191) PREDICTED: dual specif ( 198) 430 100.4 1.8e-21
NP_057448 (OMIM: 613191) dual specificity protein ( 198) 430 100.4 1.8e-21
XP_016871802 (OMIM: 613191) PREDICTED: dual specif ( 246) 430 100.5 2.2e-21
NP_001007273 (OMIM: 613191) dual specificity prote ( 248) 430 100.5 2.2e-21
XP_005269944 (OMIM: 613191) PREDICTED: dual specif ( 291) 430 100.5 2.6e-21
NP_001007274 (OMIM: 613191) dual specificity prote ( 291) 430 100.5 2.6e-21
NP_001307771 (OMIM: 613191) dual specificity prote ( 291) 430 100.5 2.6e-21
XP_011538155 (OMIM: 613191) PREDICTED: dual specif ( 327) 430 100.5 2.8e-21
XP_005269941 (OMIM: 613191) PREDICTED: dual specif ( 334) 430 100.5 2.9e-21
XP_005269940 (OMIM: 613191) PREDICTED: dual specif ( 417) 430 100.6 3.5e-21
XP_011529426 (OMIM: 300134) PREDICTED: dual specif ( 384) 285 69.9 5.6e-12
NP_001386 (OMIM: 300134) dual specificity protein ( 384) 285 69.9 5.6e-12
NP_001305432 (OMIM: 300134) dual specificity prote ( 384) 285 69.9 5.6e-12
XP_011529425 (OMIM: 300134) PREDICTED: dual specif ( 415) 285 69.9 6e-12
NP_009138 (OMIM: 608867) dual specificity protein ( 482) 283 69.5 9.2e-12
NP_001938 (OMIM: 602749) dual specificity protein ( 419) 278 68.4 1.7e-11
NP_001937 (OMIM: 602748,615269) dual specificity p ( 381) 268 66.3 6.8e-11
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 251 62.7 8.2e-10
XP_011535410 (OMIM: 615814) PREDICTED: serine/thre ( 199) 240 60.2 2.3e-09
NP_660294 (OMIM: 615814) serine/threonine/tyrosine ( 223) 240 60.3 2.6e-09
NP_001124173 (OMIM: 615814) serine/threonine/tyros ( 223) 240 60.3 2.6e-09
XP_011542730 (OMIM: 602747) PREDICTED: dual specif ( 303) 236 59.5 6e-09
NP_476499 (OMIM: 602747) dual specificity protein ( 303) 236 59.5 6e-09
NP_001385 (OMIM: 602747) dual specificity protein ( 394) 236 59.5 7.6e-09
NP_004408 (OMIM: 600714) dual specificity protein ( 367) 233 58.9 1.1e-08
NP_543152 (OMIM: 611437) dual specificity protein ( 217) 225 57.1 2.2e-08
NP_004409 (OMIM: 603068) dual specificity protein ( 314) 225 57.1 3.1e-08
XP_016859035 (OMIM: 603068) PREDICTED: dual specif ( 342) 225 57.2 3.4e-08
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 218 55.8 1.7e-07
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 218 55.8 1.7e-07
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 218 55.8 1.7e-07
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 218 55.8 1.7e-07
XP_005253545 (OMIM: 607175) PREDICTED: dual specif ( 517) 206 53.2 7.9e-07
XP_016875477 (OMIM: 607175) PREDICTED: dual specif ( 517) 206 53.2 7.9e-07
NP_071359 (OMIM: 300678) dual specificity protein ( 190) 195 50.7 1.6e-06
NP_009171 (OMIM: 604835) dual specificity protein ( 340) 191 50.0 4.9e-06
XP_011528222 (OMIM: 611446) PREDICTED: dual specif ( 188) 187 49.0 5.2e-06
XP_011528223 (OMIM: 611446) PREDICTED: dual specif ( 188) 187 49.0 5.2e-06
NP_001291723 (OMIM: 611446) dual specificity prote ( 188) 187 49.0 5.2e-06
XP_006724211 (OMIM: 611446) PREDICTED: dual specif ( 188) 187 49.0 5.2e-06
NP_001291724 (OMIM: 611446) dual specificity prote ( 188) 187 49.0 5.2e-06
NP_689724 (OMIM: 611446) dual specificity protein ( 188) 187 49.0 5.2e-06
XP_005261425 (OMIM: 611446) PREDICTED: dual specif ( 188) 187 49.0 5.2e-06
XP_016884116 (OMIM: 611446) PREDICTED: dual specif ( 188) 187 49.0 5.2e-06
>>NP_004081 (OMIM: 600183) dual specificity protein phos (185 aa)
initn: 1217 init1: 1217 opt: 1217 Z-score: 1406.6 bits: 266.9 E(85289): 1.3e-71
Smith-Waterman score: 1217; 100.0% identity (100.0% similar) in 185 aa overlap (1-185:1-185)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
130 140 150 160 170 180
pF1KE5 GKLKP
:::::
NP_004 GKLKP
>>NP_001007272 (OMIM: 613191) dual specificity protein p (188 aa)
initn: 432 init1: 331 opt: 465 Z-score: 546.7 bits: 107.8 E(85289): 1e-23
Smith-Waterman score: 465; 44.3% identity (73.9% similar) in 176 aa overlap (8-182:20-187)
10 20 30 40
pF1KE5 MSGSFELSVQDLNDLLSDG-SGCYSLPSQPCNEVTPRIYVGNASVAQD
:. .:..:: : :.: . .:: : ...:.:..:..
NP_001 MAETSLPELGGEDKATPCPSILELEELLRAGKSSCSRV-----DEVWPNLFIGDAATANN
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 IPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAAD
.: :::::::::::. . .. . . .:: :...:::. :.: .:..:::: :::
NP_001 RFELWKLGITHVLNAAH--KGLYCQGGPDFY-GSSVSYLGVPAHDLPDFDISAYFSSAAD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 FIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFL
:: .:: ...::::: : ::: :::.::::..:......:. :::.: . :: :::
NP_001 FIHRALNTPGAKVLVHCVVGVSRSATLVLAYLMLHQRLSLRQAVITVRQHRWVFPNRGFL
120 130 140 150 160 170
170 180
pF1KE5 AQLCQLNDRLAKEGKLKP
:::.:...: :.
NP_001 HQLCRLDQQLRGAGQS
180
>>NP_001307772 (OMIM: 613191) dual specificity protein p (198 aa)
initn: 410 init1: 301 opt: 430 Z-score: 506.3 bits: 100.4 E(85289): 1.8e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:47-194)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
NP_001 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
NP_001 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
NP_001 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
140 150 160 170 180 190
pF1KE5 GKLKP
NP_001 TGRF
>>XP_011538158 (OMIM: 613191) PREDICTED: dual specificit (198 aa)
initn: 410 init1: 301 opt: 430 Z-score: 506.3 bits: 100.4 E(85289): 1.8e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:47-194)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
XP_011 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
XP_011 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
XP_011 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
140 150 160 170 180 190
pF1KE5 GKLKP
XP_011 TGRF
>>XP_011538156 (OMIM: 613191) PREDICTED: dual specificit (198 aa)
initn: 410 init1: 301 opt: 430 Z-score: 506.3 bits: 100.4 E(85289): 1.8e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:47-194)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
XP_011 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
XP_011 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
XP_011 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
140 150 160 170 180 190
pF1KE5 GKLKP
XP_011 TGRF
>>XP_011538157 (OMIM: 613191) PREDICTED: dual specificit (198 aa)
initn: 410 init1: 301 opt: 430 Z-score: 506.3 bits: 100.4 E(85289): 1.8e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:47-194)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
XP_011 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
XP_011 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
XP_011 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
140 150 160 170 180 190
pF1KE5 GKLKP
XP_011 TGRF
>>XP_005269947 (OMIM: 613191) PREDICTED: dual specificit (198 aa)
initn: 410 init1: 301 opt: 430 Z-score: 506.3 bits: 100.4 E(85289): 1.8e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:47-194)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
XP_005 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
XP_005 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
XP_005 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
140 150 160 170 180 190
pF1KE5 GKLKP
XP_005 TGRF
>>NP_057448 (OMIM: 613191) dual specificity protein phos (198 aa)
initn: 410 init1: 301 opt: 430 Z-score: 506.3 bits: 100.4 E(85289): 1.8e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:47-194)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
NP_057 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
NP_057 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
NP_057 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
140 150 160 170 180 190
pF1KE5 GKLKP
NP_057 TGRF
>>XP_016871802 (OMIM: 613191) PREDICTED: dual specificit (246 aa)
initn: 427 init1: 301 opt: 430 Z-score: 504.8 bits: 100.5 E(85289): 2.2e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:95-242)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
XP_016 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
XP_016 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
XP_016 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
190 200 210 220 230 240
pF1KE5 GKLKP
XP_016 TGRF
>>NP_001007273 (OMIM: 613191) dual specificity protein p (248 aa)
initn: 410 init1: 301 opt: 430 Z-score: 504.8 bits: 100.5 E(85289): 2.2e-21
Smith-Waterman score: 430; 47.3% identity (76.0% similar) in 150 aa overlap (31-180:97-244)
10 20 30 40 50 60
pF1KE5 MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
.:: : ...:.: .:.: :: .::::::.
NP_001 AVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYAARDKSKLIQLGITHVV
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE5 NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
::: :. ..:.:.:.::. .. : ::.:.:. :.::.:: .: .: ::. .:::
NP_001 NAAAGK--FQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVARYIRAALSVPQGRV
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE5 LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
:::: : ::: :::.:.::. ..: . :.. :. .:.: ::.::: :: :..::..:
NP_001 LVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGFLRQLQVLDNRLGRE
190 200 210 220 230 240
pF1KE5 GKLKP
NP_001 TGRF
185 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:33:18 2016 done: Mon Nov 7 22:33:19 2016
Total Scan time: 4.960 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]