Result of FASTA (ccds) for
pFN21AE5206
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5206, 251 aa
1>>>pF1KE5206 251 - 251 aa - 251 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7131+/-0.000849; mu= 11.9405+/- 0.051
mean_var=66.5607+/-13.244, 0's: 0 Z-trim(106.5): 21 B-trim: 12 in 1/50
Lambda= 0.157205
statistics sampled from 8997 (9017) to 8997 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.277), width: 16
Scan time: 1.900
The best scores are: opt bits E(32554)
CCDS4914.1 CLIC5 gene_id:53405|Hs108|chr6 ( 251) 1655 384.1 4.8e-107
CCDS47438.1 CLIC5 gene_id:53405|Hs108|chr6 ( 410) 1566 364.0 8.9e-101
CCDS59022.1 CLIC5 gene_id:53405|Hs108|chr6 ( 205) 1298 303.1 9.5e-83
CCDS256.1 CLIC4 gene_id:25932|Hs108|chr1 ( 253) 1278 298.6 2.7e-81
CCDS13638.1 CLIC6 gene_id:54102|Hs108|chr21 ( 686) 1215 284.5 1.3e-76
CCDS82669.1 CLIC6 gene_id:54102|Hs108|chr21 ( 704) 1194 279.7 3.6e-75
CCDS14767.1 CLIC2 gene_id:1193|Hs108|chrX ( 247) 1086 255.1 3.3e-68
CCDS4719.1 CLIC1 gene_id:1192|Hs108|chr6 ( 241) 1020 240.1 1e-63
CCDS7021.1 CLIC3 gene_id:9022|Hs108|chr9 ( 236) 771 183.6 1e-46
>>CCDS4914.1 CLIC5 gene_id:53405|Hs108|chr6 (251 aa)
initn: 1655 init1: 1655 opt: 1655 Z-score: 2035.2 bits: 384.1 E(32554): 4.8e-107
Smith-Waterman score: 1655; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251)
10 20 30 40 50 60
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 LTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELA
190 200 210 220 230 240
250
pF1KE5 YADVAKRLSRS
:::::::::::
CCDS49 YADVAKRLSRS
250
>>CCDS47438.1 CLIC5 gene_id:53405|Hs108|chr6 (410 aa)
initn: 1563 init1: 1563 opt: 1566 Z-score: 1922.7 bits: 364.0 E(32554): 8.9e-101
Smith-Waterman score: 1566; 97.9% identity (98.4% similar) in 243 aa overlap (9-251:168-410)
10 20 30
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRL
: .::: :::::::::::::::::::::
CCDS47 PSSFTIQHSKAFSTTKYSCYSDAEGLEEKEGAHMNPEIYLFVKAGIDGESIGNCPFSQRL
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE5 FMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTP
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE5 EKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPE
260 270 280 290 300 310
160 170 180 190 200 210
pF1KE5 EIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 EIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYL
320 330 340 350 360 370
220 230 240 250
pF1KE5 KNAYARDEFTNTCAADSEIELAYADVAKRLSRS
:::::::::::::::::::::::::::::::::
CCDS47 KNAYARDEFTNTCAADSEIELAYADVAKRLSRS
380 390 400 410
>>CCDS59022.1 CLIC5 gene_id:53405|Hs108|chr6 (205 aa)
initn: 1298 init1: 1298 opt: 1298 Z-score: 1599.1 bits: 303.1 E(32554): 9.5e-83
Smith-Waterman score: 1298; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 LTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELA
::::::::::::::::
CCDS59 LTLADCNLLPKLHVVKEQVPLKGMI
190 200
>>CCDS256.1 CLIC4 gene_id:25932|Hs108|chr1 (253 aa)
initn: 1304 init1: 1253 opt: 1278 Z-score: 1573.1 bits: 298.6 E(32554): 2.7e-81
Smith-Waterman score: 1278; 74.7% identity (89.3% similar) in 253 aa overlap (1-250:1-253)
10 20 30 40 50
pF1KE5 MTDSATANG---DDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLK
:. : :: .:..: :::::::: :::::::::::::::::::::::::.:::::::
CCDS25 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 RKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGID
::::::.::::::::::.:::..::::::::::::::.: : :: ::. :: ::::::.:
CCDS25 RKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 IFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLD
::.::::::::.. . : :::::: :.:.:::.:::.:::.::: :. . : : :::::
CCDS25 IFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFLD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 GDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEI
:.:.::::::::::::.::.:::::::.::: ::::.:::: :::.:::::::: .:.:.
CCDS25 GNEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKEV
190 200 210 220 230 240
240 250
pF1KE5 ELAYADVAKRLSRS
:.::.::::::..
CCDS25 EIAYSDVAKRLTK
250
>>CCDS13638.1 CLIC6 gene_id:54102|Hs108|chr21 (686 aa)
initn: 1265 init1: 1206 opt: 1215 Z-score: 1488.9 bits: 284.5 E(32554): 1.3e-76
Smith-Waterman score: 1215; 74.0% identity (90.5% similar) in 242 aa overlap (7-248:446-685)
10 20 30
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQ
: :...: : :::::: ::::::::::::
CCDS13 HLAEEGPAEGSGEAARVNGRREDGEASEPRALGQEHD--ITLFVKAGYDGESIGNCPFSQ
420 430 440 450 460 470
40 50 60 70 80 90
pF1KE5 RLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETL
:::::::::::.:::::::::::::::.::::::.:::.::.:.:::::::::::::: :
CCDS13 RLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKL
480 490 500 510 520 530
100 110 120 130 140 150
pF1KE5 TPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPL
.: .::::...: :::.:: :.:.::::.:::::.. : :..: :::.:::.:::.::
CCDS13 APPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPL
540 550 560 570 580 590
160 170 180 190 200 210
pF1KE5 PEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWR
:.:::: . . : :::::::::::::::::::::..::::::::....:.::::.::
CCDS13 PDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWR
600 610 620 630 640 650
220 230 240 250
pF1KE5 YLKNAYARDEFTNTCAADSEIELAYADVAKRLSRS
::.:::::::::::: ::.::: ::.:::::.
CCDS13 YLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK
660 670 680
>>CCDS82669.1 CLIC6 gene_id:54102|Hs108|chr21 (704 aa)
initn: 1241 init1: 1182 opt: 1194 Z-score: 1463.0 bits: 279.7 E(32554): 3.6e-75
Smith-Waterman score: 1194; 72.4% identity (89.7% similar) in 243 aa overlap (6-248:462-703)
10 20 30
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFS
:: : .: :. ...:: :::::::::::
CCDS82 VNGRREDGEASEPRALGQEHDITLFVKVKLTALGCSR-IAIKKYLRAGYDGESIGNCPFS
440 450 460 470 480 490
40 50 60 70 80 90
pF1KE5 QRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEET
::::::::::::.:::::::::::::::.::::::.:::.::.:.::::::::::::::
CCDS82 QRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEK
500 510 520 530 540 550
100 110 120 130 140 150
pF1KE5 LTPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTP
:.: .::::...: :::.:: :.:.::::.:::::.. : :..: :::.:::.:::.:
CCDS82 LAPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSP
560 570 580 590 600 610
160 170 180 190 200 210
pF1KE5 LPEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLW
::.:::: . . : :::::::::::::::::::::..::::::::....:.::::.:
CCDS82 LPDEIDAYSTEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIW
620 630 640 650 660 670
220 230 240 250
pF1KE5 RYLKNAYARDEFTNTCAADSEIELAYADVAKRLSRS
:::.:::::::::::: ::.::: ::.:::::.
CCDS82 RYLNNAYARDEFTNTCPADQEIEHAYSDVAKRMK
680 690 700
>>CCDS14767.1 CLIC2 gene_id:1193|Hs108|chrX (247 aa)
initn: 1147 init1: 1082 opt: 1086 Z-score: 1337.9 bits: 255.1 E(32554): 3.3e-68
Smith-Waterman score: 1086; 65.6% identity (86.7% similar) in 241 aa overlap (9-249:7-247)
10 20 30 40 50 60
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
: . ::::::::::: :::::::::: :::::::::::: :::::::. :::
CCDS14 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKP
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
.:..:::::.::::..: ..::: :::::::.::.: .::.:. :..:: .: ..:.
CCDS14 EELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
:::::::::... : .:..: : .:.::::::::: .::: .. : ::: :::::.
CCDS14 KFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 LTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELA
::::::.:::::...:..:::::..:::::..:.::::.:::::.:::.:: :.::: .
CCDS14 LTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENT
180 190 200 210 220 230
250
pF1KE5 YADVAKRLSRS
::.:::. :
CCDS14 YANVAKQKS
240
>>CCDS4719.1 CLIC1 gene_id:1192|Hs108|chr6 (241 aa)
initn: 1021 init1: 994 opt: 1020 Z-score: 1257.2 bits: 240.1 E(32554): 1e-63
Smith-Waterman score: 1020; 64.9% identity (84.5% similar) in 239 aa overlap (11-248:3-240)
10 20 30 40 50 60
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
...:..::::::: :: .::::::::::::.::::::.::::::: ::.
CCDS47 MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRT
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
...: :: . ::: .. .:.::.:::::::: .: : .:::::: . ::::::.:::.
CCDS47 ETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFA
60 70 80 90 100 110
130 140 150 160 170
pF1KE5 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKG-SRRKFLDGD
::::::::.. : ::.:: :::: ::.::..:::::.: .: .::.: :.::::::.
CCDS47 KFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVD-ETSAEDEGVSQRKFLDGN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 ELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIEL
::::::::::::::.:..: ::::.. :: . :. :::.:::::.::..:: : ::::
CCDS47 ELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIEL
180 190 200 210 220 230
240 250
pF1KE5 AYADVAKRLSRS
:: .::: :
CCDS47 AYEQVAKALK
240
>>CCDS7021.1 CLIC3 gene_id:9022|Hs108|chr9 (236 aa)
initn: 793 init1: 521 opt: 771 Z-score: 952.1 bits: 183.6 E(32554): 1e-46
Smith-Waterman score: 771; 52.0% identity (77.3% similar) in 229 aa overlap (13-241:3-229)
10 20 30 40 50 60
pF1KE5 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
. ...:::::. ::::.:.:: :::::.: :::: :..:::: .:.:
CCDS70 MAETKLQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSP
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
:...:::.. :.: ...:.:::. .::.:::::: : .:.:: ..::::::: :.:
CCDS70 DVLKDFAPGSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFH
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
::::.::: .. :: . : .:: .::.:: .:: .:. .. . . :::.:::::.
CCDS70 KFSAFIKNPVPAQDEALYQQLLRALARLDSYLRAPLEHELAGEP--QLRESRRRFLDGDR
120 130 140 150 160
190 200 210 220 230 240
pF1KE5 LTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELA
::::::.::::::.: : ..:. ::::. :. ::: .:. . :: :: ..:: :
CCDS70 LTLADCSLLPKLHIVDTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAA
170 180 190 200 210 220
250
pF1KE5 YADVAKRLSRS
:
CCDS70 YRPAVHPR
230
251 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:30:10 2016 done: Mon Nov 7 22:30:10 2016
Total Scan time: 1.900 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]